Stock 129(B6)-Thy1<tm1Rjmo>/H

FESA Number

5729

Strain Name

129(B6)-Thy1<tm1Rjmo>/H

Mutation Strain Type

Attribution

Institution name Depositor / Originator Name
Unknown Institution Originator Retained
Unknown Institution Depositor Retained

Phenotypic Description

Nervous system: reduced long term potentiation (J:31610). Strong inhibition of LTP in the dentate gyrus but not in CA1, however spatial learning as assessed in the watermaze is unimpaired. Respiratory system: pulmonary fibrosis (J:99951). Marked increase in severity of lung fibrosis and more extensive collagen deposition in response to intratracheal bleomycin, compared to controls.

Publications

EMMA ID

EM:07002

Genetic Status

GMO

Background Strain Name

129S/SvEv

Background Strain MGI ID

MGI:3050593

Strain Sanitary Status

None (however, the unit does not exclude MNV and Helicobacter).

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