Stock 129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]
FESA Number
2900
Strain Name
129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]
Mutation Strain Type
Attribution
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Apoe<tm1Bres> | MGI:2137814 | Apoe | MGI:88057 | 7 |
| Plg<tm1Jld> | MGI:1857291 | Plg | MGI:97620 | 17 |
Phenotypic Description
Rectal prolapse. Shortened life span in homozygotes.
Orphanet Disorders
| OrphaNet ID | Name | Url |
|---|---|---|
| 722 | Hypoplasminogenemia | http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=722 |
| 97 231 | Ligneous conjunctivitis | http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=97231 |
Publications
Displaying 91 - 100 of 171 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 12213722 | Jormsjö S | Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice. | Am J Pathol (2 002) 161:939-45 |
| 7498401 | Masliah E | Neurodegeneration in the central nervous system of apoE-deficient mice. | Exp Neurol (1 995) 136:107-22 |
| 9483513 | Robertson TA | Age-related congophilic inclusions in the brains of apolipoprotein E-deficient mice. | Neuroscience (1 998) 82:171-80 |
| 18988889 | Thorp E | Brief report: increased apoptosis in advanced atherosclerotic lesions of Apoe-/- mice lacking macrophage Bcl-2. | Arterioscler Thromb Vasc Biol (2 009) 29:169-72 |
| 12431986 | Yamauchi T | Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. | J Biol Chem (2 003) 278:2461-8 |
| 12857855 | Chen ZL | The hippocampal laminin matrix is dynamic and critical for neuronal survival. | Mol Biol Cell (2 003) 14:2665-76 |
| 15841177 | Liu Z | Synergy between a plasminogen cascade and MMP-9 in autoimmune disease. | J Clin Invest (2 005) 115:879-87 |
| 16818777 | Renckens R | Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice. | J Immunol (2 006) 177:1189-96 |
| 19147818 | Zhang C | The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain. | Am J Pathol (2 009) 174:586-94 |
| 11592107 | Calara F | Spontaneous plaque rupture and secondary thrombosis in apolipoprotein E-deficient and LDL receptor-deficient mice. | J Pathol (2 001) 195:257-63 |
Pages
Orphanet Categories
Rare systemic or rheumatologic disease
Rare eye disease
EMMA ID
EM:02065
Genetic Status
GMO
Background Strain Name
129
Background Strain MGI ID
MGI:2160041
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