Stock

FESA Number

2900

Strain Name

129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plg<tm1Jld> MGI:1857291 Plg MGI:97620 17

Phenotypic Description

Rectal prolapse. Shortened life span in homozygotes.

Orphanet Disorders

Publications

Displaying 91 - 100 of 171 Stock Publications
Pubmed ID Authors Title Journal
12213722 Jormsjö S Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice. Am J Pathol (2 002) 161:939-45
7498401 Masliah E Neurodegeneration in the central nervous system of apoE-deficient mice. Exp Neurol (1 995) 136:107-22
9483513 Robertson TA Age-related congophilic inclusions in the brains of apolipoprotein E-deficient mice. Neuroscience (1 998) 82:171-80
18988889 Thorp E Brief report: increased apoptosis in advanced atherosclerotic lesions of Apoe-/- mice lacking macrophage Bcl-2. Arterioscler Thromb Vasc Biol (2 009) 29:169-72
12431986 Yamauchi T Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis. J Biol Chem (2 003) 278:2461-8
12857855 Chen ZL The hippocampal laminin matrix is dynamic and critical for neuronal survival. Mol Biol Cell (2 003) 14:2665-76
15841177 Liu Z Synergy between a plasminogen cascade and MMP-9 in autoimmune disease. J Clin Invest (2 005) 115:879-87
16818777 Renckens R Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice. J Immunol (2 006) 177:1189-96
19147818 Zhang C The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain. Am J Pathol (2 009) 174:586-94
11592107 Calara F Spontaneous plaque rupture and secondary thrombosis in apolipoprotein E-deficient and LDL receptor-deficient mice. J Pathol (2 001) 195:257-63

Pages

Orphanet Categories

Rare systemic or rheumatologic disease
Rare eye disease

EMMA ID

EM:02065

Genetic Status

GMO

Background Strain Name

129

Background Strain MGI ID

MGI:2160041

Contact/Order

For more information or to order stocks, Contact us