Stock 129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]
FESA Number
2900
Strain Name
129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]
Mutation Strain Type
Attribution
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Apoe<tm1Bres> | MGI:2137814 | Apoe | MGI:88057 | 7 |
| Plg<tm1Jld> | MGI:1857291 | Plg | MGI:97620 | 17 |
Phenotypic Description
Rectal prolapse. Shortened life span in homozygotes.
Orphanet Disorders
| OrphaNet ID | Name | Url |
|---|---|---|
| 722 | Hypoplasminogenemia | http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=722 |
| 97 231 | Ligneous conjunctivitis | http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=97231 |
Publications
Displaying 81 - 90 of 171 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 10720491 | Maor I | Oxidized monocyte-derived macrophages in aortic atherosclerotic lesion from apolipoprotein E-deficient mice and from human carotid artery contain lipid peroxides and oxysterols. | Biochem Biophys Res Commun (2 000) 269:775-80 |
| 15567863 | Ricci R | Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. | Science (2 004) 306:1558-61 |
| 14976060 | Tan MH | Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis. | Blood (2 004) 104:11-8 |
| 21889487 | Xu S | Tanshinone II-A attenuates and stabilizes atherosclerotic plaques in apolipoprotein-E knockout mice fed a high cholesterol diet. | Arch Biochem Biophys (2 011) 515:72-9 |
| 10559390 | Chen ZL | Neuronal death and blood-brain barrier breakdown after excitotoxic injury are independent processes. | J Neurosci (1 999) 19:9813-20 |
| 10642175 | List K | Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice. | Biochemistry (2 000) 39:508-15 |
| 11733368 | Pohl JF | Plasminogen deficiency leads to impaired lobular reorganization and matrix accumulation after chronic liver injury. | Am J Pathol (2 001) 159:2179-86 |
| 12070304 | Yepes M | Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent. | J Clin Invest (2 002) 109:1571-8 |
| 8816744 | Bourassa PA | Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice. | Proc Natl Acad Sci U S A (1 996) 93:10022-7 |
| 14525797 | Hayek T | Tissue angiotensin-converting-enzyme (ACE) deficiency leads to a reduction in oxidative stress and in atherosclerosis: studies in ACE-knockout mice type 2. | Arterioscler Thromb Vasc Biol (2 003) 23:2090-6 |
Pages
Orphanet Categories
Rare systemic or rheumatologic disease
Rare eye disease
EMMA ID
EM:02065
Genetic Status
GMO
Background Strain Name
129
Background Strain MGI ID
MGI:2160041
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