Stock

FESA Number

2900

Strain Name

129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plg<tm1Jld> MGI:1857291 Plg MGI:97620 17

Phenotypic Description

Rectal prolapse. Shortened life span in homozygotes.

Orphanet Disorders

Publications

Displaying 61 - 70 of 171 Stock Publications
Pubmed ID Authors Title Journal
21042583 Stein S ApoE-/- PGC-1?-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis. PLoS One (2 010) 5:e13539
9486990 Xiao Q Fibrinogen deficiency is compatible with the development of atherosclerosis in mice. J Clin Invest (1 998) 101:1184-94
15985536 Cheng Q The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice. Blood (2 005) 106:3055-7
21326869 Juncker-Jensen A Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice. PLoS One (2 011) 6:e16954
16330749 Pawlak R Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus. Proc Natl Acad Sci U S A (2 005) 102:18201-6
15364412 Tucker HM Plasmin deficiency does not alter endogenous murine amyloid beta levels in mice. Neurosci Lett (2 004) 368:285-9
18197246 Bhasin JM Sex specific gene regulation and expression QTLs in mouse macrophages from a strain intercross. PLoS One (2 008) 3:e1435
8710189 Gordon I Derangement in stress response of apolipoprotein E-deficient mice. Neurosci Lett (1 996) 206:212-4
16702468 Johnson JL Suppression of atherosclerotic plaque progression and instability by tissue inhibitor of metalloproteinase-2: involvement of macrophage migration and apoptosis. Circulation (2 006) 113:2435-44
11498466 Lutgens E Compensatory enlargement and stenosis develop in apoE(-/-) and apoE*3-Leiden transgenic mice. Arterioscler Thromb Vasc Biol (2 001) 21:1359-65

Pages

Orphanet Categories

Rare systemic or rheumatologic disease
Rare eye disease

EMMA ID

EM:02065

Genetic Status

GMO

Background Strain Name

129

Background Strain MGI ID

MGI:2160041

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