Stock

FESA Number

2900

Strain Name

129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plg<tm1Jld> MGI:1857291 Plg MGI:97620 17

Phenotypic Description

Rectal prolapse. Shortened life span in homozygotes.

Orphanet Disorders

Publications

Displaying 141 - 150 of 171 Stock Publications
Pubmed ID Authors Title Journal
14709993 Samara GJ The effects of the plasminogen pathway on scar tissue formation. Laryngoscope (2 004) 114:46-9
11597942 Dansky HM Adhesion of monocytes to arterial endothelium and initiation of atherosclerosis are critically dependent on vascular cell adhesion molecule-1 gene dosage. Arterioscler Thromb Vasc Biol (2 001) 21:1662-7
21521871 Herman-Edelstein M Dedifferentiation of immortalized human podocytes in response to transforming growth factor-?: a model for diabetic podocytopathy. Diabetes (2 011) 60:1779-88
11090485 Kliffen M The APO(*)E3-Leiden mouse as an animal model for basal laminar deposit. Br J Ophthalmol (2 000) 84:1415-9
9507996 Neuzil J Radical-induced lipoprotein and plasma lipid oxidation in normal and apolipoprotein E gene knockout (apoE-/-) mice: apoE-/- mouse as a model for testing the role of tocopherol-mediated peroxidation in atherogenesis. J Lipid Res (1 998) 39:354-68
10725355 Sehayek E Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: studies in C57BL/6 apolipoprotein E knockout mice. Proc Natl Acad Sci U S A (2 000) 97:3433-7
9682819 Veinbergs I Altered long-term potentiation in the hippocampus of apolipoprotein E-deficient mice. Neurosci Lett (1 998) 249:71-4
17097058 Zhuge X Protection of atherogenesis in thromboxane A2 receptor-deficient mice is not associated with thromboxane A2 receptor in bone marrow-derived cells. Biochem Biophys Res Commun (2 006) 351:865-71
10903997 Drew AF Plasminogen is a critical determinant of vascular remodeling in mice. Circ Res (2 000) 87:133-9
18042398 Minor KH Plasminogen activator induction facilitates recovery of respiratory function following spinal cord injury. Mol Cell Neurosci (2 008) 37:143-52

Pages

Orphanet Categories

Rare systemic or rheumatologic disease
Rare eye disease

EMMA ID

EM:02065

Genetic Status

GMO

Background Strain Name

129

Background Strain MGI ID

MGI:2160041

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