Stock 129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

FESA Number


Strain Name

129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

Mutation Strain Type


Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plat<tm1Mlg> MGI:1857288 Plat MGI:97610 8

Phenotypic Description



Displaying 181 - 190 of 240 Stock Publications
Pubmed ID Authors Title Journal
9453565 Chapman S Specific neurochemical derangements of brain projecting neurons in apolipoprotein E-deficient mice. J Neurochem (1 998) 70:708-14
16043658 Heller EA Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation (2 005) 112:578-86
9245700 Keidar S The angiotensin-II receptor antagonist, losartan, inhibits LDL lipid peroxidation and atherosclerosis in apolipoprotein E-deficient mice. Biochem Biophys Res Commun (1 997) 236:622-5
8274468 Nakashima Y ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler Thromb (1 994) 14:133-40
22952653 Schurgers LJ Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype. PLoS One (2 012) 7:e43229
10336088 Veinbergs I Synaptic alterations in apolipoprotein E knockout mice. Neuroscience (1 999) 91:401-3
18689793 Zhang QJ Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc Res (2 008) 80:191-9
10559390 Chen ZL Neuronal death and blood-brain barrier breakdown after excitotoxic injury are independent processes. J Neurosci (1 999) 19:9813-20
10502816 Heymans S Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nat Med (1 999) 5:1135-42
17936515 Lee SR Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia. Neuroscience (2 007) 150:50-7




Genetic Status


Background Strain Name


Background Strain MGI ID



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