Stock

FESA Number

2897

Strain Name

129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plat<tm1Mlg> MGI:1857288 Plat MGI:97610 8

Phenotypic Description

None.

Publications

Displaying 171 - 180 of 240 Stock Publications
Pubmed ID Authors Title Journal
11421580 Veinbergs I Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E. Exp Neurol (2 001) 170:15-26
12860569 Yuan Z Immunoglobulin treatment suppresses atherosclerosis in apolipoprotein E-deficient mice via the Fc portion. Am J Physiol Heart Circ Physiol (2 003) 285:H899-906
19114596 Chen ZL Proteolytic fragments of laminin promote excitotoxic neurodegeneration by up-regulation of the KA1 subunit of the kainate receptor. J Cell Biol (2 008) 183:1299-1313
15631996 Heymans S Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice. Am J Pathol (2 005) 166:15-25
15451307 Kumada M Endogenous tissue type plasminogen activator facilitates NMDA-induced retinal damage. Toxicol Appl Pharmacol (2 004) 200:48-53
19181855 Maiya R Tissue plasminogen activator modulates the cellular and behavioral response to cocaine. Proc Natl Acad Sci U S A (2 009) 106:1983-8
9119016 Ny A Studies of mice lacking plasminogen activator gene function suggest that plasmin production prior to ovulation exceeds the amount needed for optimal ovulation efficiency. Eur J Biochem (1 997) 244:487-93
17114493 Renckens R Plasminogen activator inhibitor type-1-deficient mice have an enhanced IFN-gamma response to lipopolysaccharide and staphylococcal enterotoxin B. J Immunol (2 006) 177:8171-6
11404420 Siconolfi LB Mice lacking tPA, uPA, or plasminogen genes showed delayed functional recovery after sciatic nerve crush. J Neurosci (2 001) 21:4348-55
19147818 Zhang C The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain. Am J Pathol (2 009) 174:586-94

Pages

EMMA ID

EM:02063

Genetic Status

GMO

Background Strain Name

129

Background Strain MGI ID

MGI:2160041

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