Stock 129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

FESA Number


Strain Name

129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

Mutation Strain Type


Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plat<tm1Mlg> MGI:1857288 Plat MGI:97610 8

Phenotypic Description



Displaying 141 - 150 of 240 Stock Publications
Pubmed ID Authors Title Journal
19416717 Thorp E Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. Cell Metab (2 009) 9:474-81
10559023 Yang R Hypertension and endothelial dysfunction in apolipoprotein E knockout mice. Arterioscler Thromb Vasc Biol (1 999) 19:2762-8
8133887 Carmeliet P Physiological consequences of loss of plasminogen activator gene function in mice. Nature (1 994) 368:419-24
20639453 Hao S tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling. Am J Pathol (2 010) 177:1164-75
10891445 Kawasaki T Vascular release of plasminogen activator inhibitor-1 impairs fibrinolysis during acute arterial thrombosis in mice. Blood (2 000) 96:153-60
12486171 Lu W Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis. J Neurosci (2 002) 22:10781-9
18000864 Nolin WB tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2. Glia (2 008) 56:177-89
12657615 Rakic JM Mice without uPA, tPA, or plasminogen genes are resistant to experimental choroidal neovascularization. Invest Ophthalmol Vis Sci (2 003) 44:1732-9
23236466 Shen Y Mice deficient in urokinase-type plasminogen activator have delayed healing of tympanic membrane perforations. PLoS One (2 012) 7:e51303
14617754 Yepes M Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. J Clin Invest (2 003) 112:1533-40




Genetic Status


Background Strain Name


Background Strain MGI ID



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