Stock 129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

FESA Number

2897

Strain Name

129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plat<tm1Mlg> MGI:1857288 Plat MGI:97610 8

Phenotypic Description

None.

Publications

Displaying 131 - 140 of 240 Stock Publications
Pubmed ID Authors Title Journal
11934869 Lu W Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator. Development (2 002) 129:2043-50
21383198 Noel M Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice. Proc Natl Acad Sci U S A (2 011) 108:5069-74
20156421 Pothakos K Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice. Brain Res (2 010) 1326:135-42
17301181 Sheehan JJ Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. J Neurosci (2 007) 27:1738-45
21486949 Yao Y Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption. J Cell Sci (2 011) 124:1486-95
11592107 Calara F Spontaneous plaque rupture and secondary thrombosis in apolipoprotein E-deficient and LDL receptor-deficient mice. J Pathol (2 001) 195:257-63
7802634 Hayek T Role of HDL apolipoprotein E in cellular cholesterol efflux: studies in apo E knockout transgenic mice. Biochem Biophys Res Commun (1 994) 205:1072-8
21372295 Katsume A Early inflammatory reactions in atherosclerosis are induced by proline-rich tyrosine kinase/reactive oxygen species-mediated release of tumor necrosis factor-alpha and subsequent activation of the p21Cip1/Ets-1/p300 system. Arterioscler Thromb Vasc Biol (2 011) 31:1084-92
8550828 Masucci-Magoulas L Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels. J Clin Invest (1 996) 97:154-61
11705823 Rong JX Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content. Circulation (2 001) 104:2447-52

Pages

EMMA ID

EM:02063

Genetic Status

GMO

Background Strain Name

129

Background Strain MGI ID

MGI:2160041

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