Stock 129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

FESA Number


Strain Name

129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - mutant strain


Institution name Depositor / Originator Name
University of Bristol Originator Retained
University of Bristol Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plat<tm1Mlg> MGI:1857288 Plat MGI:97610 8

Phenotypic Description



Displaying 1 - 10 of 240 Stock Publications
Pubmed ID Authors Title Journal
10192911 Adan Y Concentration of serum lipids and aortic lesion size in female and male apo E-deficient mice fed docosahexaenoic acid. Biosci Biotechnol Biochem (1 999) 63:309-13
10484545 Deckert V Impairment of endothelium-dependent arterial relaxation by high-fat feeding in ApoE-deficient mice: toward normalization by human ApoA-I expression. Circulation (1 999) 100:1230-5
11160157 Hodgin JB Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice. J Clin Invest (2 001) 107:333-40
16100042 Lee K Alterations in internal elastic lamina permeability as a function of age and anatomical site precede lesion development in apolipoprotein E-null mice. Circ Res (2 005) 97:450-6
8527231 Plump AS Apolipoprotein E and the apolipoprotein E-deficient mouse. Annu Rev Nutr (1 995) 15:495-518
21571684 Shim J Genetic susceptibility of the arterial wall is an important determinant of atherosclerosis in C57BL/6 and FVB/N mouse strains. Arterioscler Thromb Vasc Biol (2 011) 31:1814-20
20952520 Wang B miR-200a Prevents renal fibrogenesis through repression of TGF-?2 expression. Diabetes (2 011) 60:280-7
10961882 Bdeir K Urokinase mediates fibrinolysis in the pulmonary microvasculature. Blood (2 000) 96:1820-6
23939410 Cops EJ Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait. Exp Neurol (2 013) 249:8-19
19461880 Hovius JW The urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferi. PLoS Pathog (2 009) 5:e1000447




Genetic Status


Background Strain Name


Background Strain MGI ID



For more information or to order stocks, Contact us