Stock 129-Tgfbr2<tm1Roes>/RoesH

FESA Number

1534

Strain Name

129-Tgfbr2<tm1Roes>/RoesH

MGI ID

MGI:3045693

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified

Attribution

Institution name Depositor / Originator Name
University College London Originator Retained
University College London Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Tgfbr2<tm1Roes> MGI:3045693 Tgfbr2 MGI:98729 9

Orphanet Disorders

OrphaNet ID Name Url
144 Hereditary nonpolyposis colon cancer http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=144
284 973 Marfan syndrome type 2 http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=284973
60 030 Loeys-Dietz syndrome type 1 http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=60030
91 387 Familial thoracic aortic aneurysm and aortic dissection http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=91387

Publications

Displaying 1 - 9 of 9 Stock Publications
Pubmed ID Authors Title Journal
15322193 Borsutzky S TGF-beta receptor signaling is critical for mucosal IgA responses. J Immunol (2 004) 173:3305-9
11070163 Cazac BB TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo. Immunity (2 000) 13:443-51
16914667 D'Antonio M TGFbeta type II receptor signaling controls Schwann cell death and proliferation in developing nerves. J Neurosci (2 006) 26:8417-27
18474727 Hauri-Hohl MM TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution. Blood (2 008) 112:626-34
20176743 Lucas T Differential roles of macrophages in diverse phases of skin repair. J Immunol (2 010) 184:3964-77
20144786 Nishimura EK Key roles for transforming growth factor beta in melanocyte stem cell maintenance. Cell Stem Cell (2 010) 6:130-40
23929912 Odaka C TGF-? type II receptor expression in thymic epithelial cells inhibits the development of Hassall's corpuscles in mice. Int Immunol (2 013) 25:633-42
23856251 Pickup MW Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-?-deficient mouse mammary carcinomas. Cancer Res (2 013) 73:5336-46
12773615 Roes J Redirection of B cell responsiveness by transforming growth factor beta receptor. Proc Natl Acad Sci U S A (2 003) 100:7241-6

Orphanet Categories

Rare gastroenterologic disease
Rare oncologic disease
Rare gynecologic or obstetric disease
Rare surgical thoracic disease
Rare systemic or rheumatologic disease
Rare circulatory system disease

EMMA ID

EM:00174

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