Stock 129-Foxa2<tm1Jrt>/H

FESA Number


Strain Name


Mutation Strain Type


Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Foxa2<tm1Jrt> MGI:1857725 Foxa2 MGI:1347476 2

Phenotypic Description

Homozygous lethal at day 8 of gestation. This mouse strain has a pre-disposition to develop mis-aligned jaws which leads to over grown teeth.


Displaying 11 - 17 of 17 Stock Publications
Pubmed ID Authors Title Journal
10642791 Klingensmith J Neural induction and patterning in the mouse in the absence of the node and its derivatives. Dev Biol (1 999) 216:535-49
9825865 Manova K Apoptosis in mouse embryos: elevated levels in pregastrulae and in the distal anterior region of gastrulae of normal and mutant mice. Dev Dyn (1 998) 213:293-308
23651855 Nowotschin S The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. Genes Dev (2 013) 27:997-1002
10498685 Perea-Gómez A HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development (1 999) 126:4499-511
9598342 Varlet I Nodal signaling and axis formation in the mouse. Cold Spring Harb Symp Quant Biol (1 997) 62:105-13
12865419 Wolfrum C Role of Foxa-2 in adipocyte metabolism and differentiation. J Clin Invest (2 003) 112:345-56
18061569 Yamanaka Y Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Dev Cell (2 007) 13:884-96





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