Imprinting Regions

Region Uniparental Duplication Proximal Breakpoint Distal Breakpoint Effects Loci
prox 2 MatDp(prox2) cent T11H Feotal/placental growth retardation, postnatal viable Gatm, Sfmbt2
prox 2 PatDp(prox2) cent T11H Normal feotal growth, placental overgrowth, postnatal viable Gatm, Sfmbt2
dist 2 MatDp(dist2) T2Wa T28H Hypoactive, lethal Nespas, Gnas
dist 2 PatDp(dist2) T2Wa T28H Hyperactive, oedematous, lethal Nespas, Gnas
dist 2 MatDp(dist2) T11H T26H? Hypoactive, lethal
dist 2 PatDp(dist2) T11H T26H? Hyperactive, oedematous, lethal
dist 2 MatDp(dist2) T26H T2Wa decreased cerebellar folding Nnat, Blcap
prox 6 MatDp(prox6) centromere to A3.2 cent T77H early embryonic lethality Sgce, Asb4, Dlx5, Calcr, Peg10, Ppp1r9a, Pon2, Pon3, Tfpi2, Casd1
prox 6 MatDp(prox6) A3.2 - to C2 T77H T6Ad Foetal growth retardation Copg2, Copg2os2, Nap1l5, Klf14, Mest, Copg2os1, Mir335
prox 6 PatDp (prox6) A3.2 - to C2 T77H T6Ad Foetal overgrowth Copg2, Copg2os2, Nap1l5, Klf14, Mest, Copg2os1, Mir335
prox 7 MatDp(prox7) cent T40Ad Foetal/Placental growth retardation, viable Peg3, Zim1, Usp29, Zim3, Zfp264, Zim2
cent 7 MatDp(cent7) Is1Ct T9H postnatal lethality. PWS Snrpn, Mkrn3, Mkrn3os, Ipw, Ube3a, Ndn, Snurf, Magel2, Snord116, Snord64, Snord115, Peg12, Atp10a
cent 7 PatDp(cent7) T43Ad / T30Ad T9H postnatal growth / viability / behaviour. AS Snrpn, Mkrn3, Mkrn3os, Ipw, Ube3a, Ndn, Snurf, Magel2, Snord116, Snord64, Snord115, Peg12, Atp10a
dist 7 MatDp(dist7) T65H ter late foetal lethality Ins2, H19, Igf2, Ascl2, Cdkn1c, Phlda2, Kcnq1, Igf2os, Cd81, Tssc4, Osbpl5, AF313042, Nap1l4, Th, Tspan32, Slc22a18, Tnfrsf23, Dhcr7, Kcnq1ot1
dist 7 PatDp(dist7) T65H ter early embryonic lethality Ins2, H19, Igf2, Ascl2, Cdkn1c, Phlda2, Kcnq1, Igf2os, Cd81, Tssc4, Osbpl5, AF313042, Nap1l4, Th, Tspan32, Slc22a18, Tnfrsf23, Dhcr7, Kcnq1ot1
dist 9 MatDp(dist9) T45H ter postnatal growth retardation Rasgrf1, Mir184
prox 11 MatDp(prox11) cent T41Ad Feotal/placental growth retardation Ddc, Grb10, Cobl, Zrsr1, Commd1
prox 11 PatDp(prox11) cent T41Ad Feotal/placental overgrowth Ddc, Grb10, Cobl, Zrsr1, Commd1
dist 12 MatDp(dist12) T52H ter (Del75H) late embryonic/neonatal lethality, & reduced growth Dlk1, Meg3, Rtl1, AF357428, AF357341, Dio3, Mir376b, Mir154, Mir337, Mir433, Mir411, Mir127, Mir380, Mir370, Mir136, AF357426, Mir134, Mir410, AF357425, Mir434, Mir431, Rian, Begain
dist 12 PatDp(dist12) T52H ter (Del75H, T31H) late embryonic lethality, & growth enhancement Dlk1, Meg3, Rtl1, AF357428, AF357341, Dio3, Mir376b, Mir154, Mir337, Mir433, Mir411, Mir127, Mir380, Mir370, Mir136, AF357426, Mir134, Mir410, AF357425, Mir434, Mir431, Rian, Begain
prox 17 PatDp(prox17) 17A3.1 17A3.3 neonatal lethality (Tme) Slc22a3, Slc22a2, Airn, Igf2r, Pde10a
cent 18 MatDp(18) cent ter foetal growth retardation? Impact
cent 18 PatDp(18) cent ter foetal growth retardation? Impact