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Imprinting Regions Publications

Imprinting Loci

Nespas

Name

neuroendocrine secretory protein antisense

Chromosome

2

Expressed parental allele: maternal (M)/ paternal (P)

P

Chromosomal Region

dist 2

Imprinting Gene Pubmed Publications

Displaying 1 - 10 of 13 Loci Publications
Pubmed ID Title Authors Journal
10 716 699 An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus. Wroe SF, Kelsey G, Skinner JA, Bodle D, Ball ST, Beechey CV, Peters J, Williamson CM Proceedings of the National Academy of Sciences of the United States of America. 2000 Mar 28;97(7):3342-6
11 056 047 Tissue-specific expression of antisense and sense transcripts at the imprinted Gnas locus. Li T, Vu TH, Zeng ZL, Nguyen BT, Hayward BE, Bonthron DT, Hu JF, Hoffman AR Genomics. 2000 Nov 1;69(3):295-304
11 118 888 The spatial and temporal expression pattern of Nesp and its antisense Nespas, in mid-gestation mouse embryos. Ball ST, Williamson CM, Hayes C, Hacker T, Peters J Mechanisms of development. 2001 Jan;100(1):79-81
11 889 554 Alternative non-coding splice variants of Nespas, an imprinted gene antisense to Nesp in the Gnas imprinting cluster. Williamson CM, Skinner JA, Kelsey G, Peters J Mammalian genome : official journal of the International Mammalian Genome Society. 2002 Feb;13(2):74-9
14 610 273 Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, Abuin A, Ramirez-Solis R, Richter LJ, Piggott J, BeltrandelRio H, Buxton EC, Edwards J, Finch RA, Friddle CJ, Gupta A, Hansen G, Hu Y, Huang W, Jaing C, Key BW Jr, Kipp P, Kohlhauff B, Ma ZQ, Markesich D, Payne R, Potter DG, Qian N, Shaw J, Schrick J, Shi ZZ, Sparks MJ, Van Sligtenhorst I, Vogel P, Walke W, Xu N, Zhu Q, Person C, Sands AT Proceedings of the National Academy of Sciences of the United States of America. 2003 Nov 25;100(24):14109-14
16 141 072 The transcriptional landscape of the mammalian genome. Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schönbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, FANTOM Consortium, RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science (New York, N.Y.). 2005 Sep 2;309(5740):1559-63
16 462 745 Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster. Williamson CM, Turner MD, Ball ST, Nottingham WT, Glenister P, Fray M, Tymowska-Lalanne Z, Plagge A, Powles-Glover N, Kelsey G, Maconochie M, Peters J Nature genetics. 2006 Mar;38(3):350-5
18 799 693 Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A Genome research. 2008 Oct;18(10):1670-9
20 427 744 Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib. Fröhlich LF, Mrakovcic M, Steinborn R, Chung UI, Bastepe M, Jüppner H Proceedings of the National Academy of Sciences of the United States of America. 2010 May 18;107(20):9275-80
21 233 130 Rex1/Zfp42 as an epigenetic regulator for genomic imprinting. Kim JD, Kim H, Ekram MB, Yu S, Faulk C, Kim J Human molecular genetics. 2011 Apr 1;20(7):1353-62

Pages

Imprinting Regions

Region Uniparental Duplication Proximal Breakpoint Distal Breakpoint Effects Loci
dist 2 MatDp(dist2) T2Wa T28H Hypoactive, lethal Nespas, Gnas
dist 2 PatDp(dist2) T2Wa T28H Hyperactive, oedematous, lethal Nespas, Gnas

Imprinting Regions Pubmed Publications

Pubmed ID Publication Title Authors Journal
648 183 Complementation studies with mouse translocations. Searle AG, Beechey CV Cytogenetics and cell genetics. 1978;20(1-6):282-303
4 000 278 Differential activity of maternally and paternally derived chromosome regions in mice. Cattanach BM, Kirk M Nature. 1985 Jun 6-12;315(6019):496-8
8 812 454 Glomerular-specific imprinting of the mouse gsalpha gene: how does this relate to hormone resistance in albright hereditary osteodystrophy? Williamson CM, Schofield J, Dutton ER, Seymour A, Beechey CV, Edwards YH, Peters J Genomics. 1996 Sep 1;36(2):280-7
9 331 332 Genetic and functional analysis of neuronatin in mice with maternal or paternal duplication of distal Chr 2. Kikyo N, Williamson CM, John RM, Barton SC, Beechey CV, Ball ST, Cattanach BM, Surani MA, Peters J Developmental biology. 1997 Oct 1;190(1):66-77
9 254 699 Peg5/Neuronatin is an imprinted gene located on sub-distal chromosome 2 in the mouse. Kagitani F, Kuroiwa Y, Wakana S, Shiroishi T, Miyoshi N, Kobayashi S, Nishida M, Kohda T, Kaneko-Ishino T, Ishino F Nucleic acids research. 1997 Sep 1;25(17):3428-32
9 691 180 Localisation of the imprinted gene neuronatin, Nnat, confirms and refines the location of a second imprinting region on mouse chromosome 2. Williamson CM, Beechey CV, Ball ST, Dutton ER, Cattanach BM, Tease C, Ishino F, Peters J Cytogenetics and cell genetics. 1998;81(1):73-8
10 036 983 Imprinting of distal mouse chromosome 2 is associated with phenotypic anomalies in utero. Williamson CM, Beechey CV, Papworth D, Wroe SF, Wells CA, Cobb L, Peters J Genetical research. 1998 Dec;72(3):255-65
15 454 552 Interactions between imprinting effects in the mouse. Cattanach BM, Beechey CV, Peters J Genetics. 2004 Sep;168(1):397-413
16 575 158 Interactions between imprinting effects: summary and review. Cattanach BM, Beechey CV, Peters J Cytogenetic and genome research. 2006;113(1-4):17-23
7 959 780 Protective protein for beta-galactosidase, Ppgb, maps to the distal imprinting region of mouse chromosome 2 but is not imprinted. Williamson CM, Dutton ER, Beechey CV, Peters J Genomics. 1994 Jul 1;22(1):240-2

Pages

Imprinting Regions Publications

Journal Authors Publication Title
(1992) Mouse Genome 90:423-424 Beechey CV et al Mapping studies of distal chromosome 2 including the imprinting region
(1997) Mouse Genome 95:687-688 Williamson CM et al