Imprinting Details for Ppp1r9a

Imprinting Loci	Chromosome	Chromosomal Region	Expressed parental allele: maternal (M)/ paternal (P)	Name
Ppp1r9a	6	prox 6	M	protein phosphatase 1, regulatory (inhibitor) subunit 9A
Gene Synonyms
Neurabin I,neurabin-I
Gene References
Hoffman BG,Zavaglia B,Witzsche J,Ruiz de Algara T,Beach M,Hoodless PA,Jones SJ,Marra MA,Helgason CD Identification of transcripts with enriched expression in the developing and adult pancreas. Genome biology. 2008();9(6):R99 PUBMED
Monk D,Wagschal A,Arnaud P,Müller PS,Parker-Katiraee L,Bourc'his D,Scherer SW,Feil R,Stanier P,Moore GE Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing. Genome research. 2008();18(8):1270-81 PUBMED
Orioli D,Colaluca IN,Stefanini M,Riva S,Dotti CG,Peverali FA Rac3-induced neuritogenesis requires binding to Neurabin I. Molecular biology of the cell. 2006();17(5):2391-400 PUBMED
Ono R,Nakamura K,Inoue K,Naruse M,Usami T,Wakisaka-Saito N,Hino T,Suzuki-Migishima R,Ogonuki N,Miki H,Kohda T,Ogura A,Yokoyama M,Kaneko-Ishino T,Ishino F Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Nature genetics. 2006();38(1):101-6 PUBMED
Carninci P,Kasukawa T,Katayama S,Gough J,Frith MC,Maeda N,Oyama R,Ravasi T,Lenhard B,Wells C,Kodzius R,Shimokawa K,Bajic VB,Brenner SE,Batalov S,Forrest AR,Zavolan M,Davis MJ,Wilming LG,Aidinis V,Allen JE,Ambesi-Impiombato A,Apweiler R,Aturaliya RN,Bailey TL,Bansal M,Baxter L,Beisel KW,Bersano T,Bono H,Chalk AM,Chiu KP,Choudhary V,Christoffels A,Clutterbuck DR,Crowe ML,Dalla E,Dalrymple BP,de Bono B,Della Gatta G,di Bernardo D,Down T,Engstrom P,Fagiolini M,Faulkner G,Fletcher CF,Fukushima T,Furuno M,Futaki S,Gariboldi M,Georgii-Hemming P,Gingeras TR,Gojobori T,Green RE,Gustincich S,Harbers M,Hayashi Y,Hensch TK,Hirokawa N,Hill D,Huminiecki L,Iacono M,Ikeo K,Iwama A,Ishikawa T,Jakt M,Kanapin A,Katoh M,Kawasawa Y,Kelso J,Kitamura H,Kitano H,Kollias G,Krishnan SP,Kruger A,Kummerfeld SK,Kurochkin IV,Lareau LF,Lazarevic D,Lipovich L,Liu J,Liuni S,McWilliam S,Madan Babu M,Madera M,Marchionni L,Matsuda H,Matsuzawa S,Miki H,Mignone F,Miyake S,Morris K,Mottagui-Tabar S,Mulder N,Nakano N,Nakauchi H,Ng P,Nilsson R,Nishiguchi S,Nishikawa S,Nori F,Ohara O,Okazaki Y,Orlando V,Pang KC,Pavan WJ,Pavesi G,Pesole G,Petrovsky N,Piazza S,Reed J,Reid JF,Ring BZ,Ringwald M,Rost B,Ruan Y,Salzberg SL,Sandelin A,Schneider C,Schönbach C,Sekiguchi K,Semple CA,Seno S,Sessa L,Sheng Y,Shibata Y,Shimada H,Shimada K,Silva D,Sinclair B,Sperling S,Stupka E,Sugiura K,Sultana R,Takenaka Y,Taki K,Tammoja K,Tan SL,Tang S,Taylor MS,Tegner J,Teichmann SA,Ueda HR,van Nimwegen E,Verardo R,Wei CL,Yagi K,Yamanishi H,Zabarovsky E,Zhu S,Zimmer A,Hide W,Bult C,Grimmond SM,Teasdale RD,Liu ET,Brusic V,Quackenbush J,Wahlestedt C,Mattick JS,Hume DA,Kai C,Sasaki D,Tomaru Y,Fukuda S,Kanamori-Katayama M,Suzuki M,Aoki J,Arakawa T,Iida J,Imamura K,Itoh M,Kato T,Kawaji H,Kawagashira N,Kawashima T,Kojima M,Kondo S,Konno H,Nakano K,Ninomiya N,Nishio T,Okada M,Plessy C,Shibata K,Shiraki T,Suzuki S,Tagami M,Waki K,Watahiki A,Okamura-Oho Y,Suzuki H,Kawai J,Hayashizaki Y, , The transcriptional landscape of the mammalian genome. Science (New York, N.Y.). 2005();309(5740):1559-63 PUBMED
Ryan XP,Alldritt J,Svenningsson P,Allen PB,Wu GY,Nairn AC,Greengard P The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology. Neuron. 2005();47(1):85-100 PUBMED
Gray PA,Fu H,Luo P,Zhao Q,Yu J,Ferrari A,Tenzen T,Yuk DI,Tsung EF,Cai Z,Alberta JA,Cheng LP,Liu Y,Stenman JM,Valerius MT,Billings N,Kim HA,Greenberg ME,McMahon AP,Rowitch DH,Stiles CD,Ma Q Mouse brain organization revealed through direct genome-scale TF expression analysis. Science (New York, N.Y.). 2004();306(5705):2255-7 PUBMED
Ono R,Shiura H,Aburatani H,Kohda T,Kaneko-Ishino T,Ishino F Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6. Genome research. 2003();13(7):1696-705 PUBMED
Okazaki N,Kikuno R,Ohara R,Inamoto S,Aizawa H,Yuasa S,Nakajima D,Nagase T,Ohara O,Koga H Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA research : an international journal for rapid publication of reports on genes and genomes. 2003();10(1):35-48 PUBMED
Show 1 more Gene References below

Okazaki Y,Furuno M,Kasukawa T,Adachi J,Bono H,Kondo S,Nikaido I,Osato N,Saito R,Suzuki H,Yamanaka I,Kiyosawa H,Yagi K,Tomaru Y,Hasegawa Y,Nogami A,Schönbach C,Gojobori T,Baldarelli R,Hill DP,Bult C,Hume DA,Quackenbush J,Schriml LM,Kanapin A,Matsuda H,Batalov S,Beisel KW,Blake JA,Bradt D,Brusic V,Chothia C,Corbani LE,Cousins S,Dalla E,Dragani TA,Fletcher CF,Forrest A,Frazer KS,Gaasterland T,Gariboldi M,Gissi C,Godzik A,Gough J,Grimmond S,Gustincich S,Hirokawa N,Jackson IJ,Jarvis ED,Kanai A,Kawaji H,Kawasawa Y,Kedzierski RM,King BL,Konagaya A,Kurochkin IV,Lee Y,Lenhard B,Lyons PA,Maglott DR,Maltais L,Marchionni L,McKenzie L,Miki H,Nagashima T,Numata K,Okido T,Pavan WJ,Pertea G,Pesole G,Petrovsky N,Pillai R,Pontius JU,Qi D,Ramachandran S,Ravasi T,Reed JC,Reed DJ,Reid J,Ring BZ,Ringwald M,Sandelin A,Schneider C,Semple CA,Setou M,Shimada K,Sultana R,Takenaka Y,Taylor MS,Teasdale RD,Tomita M,Verardo R,Wagner L,Wahlestedt C,Wang Y,Watanabe Y,Wells C,Wilming LG,Wynshaw-Boris A,Yanagisawa M,Yang I,Yang L,Yuan Z,Zavolan M,Zhu Y,Zimmer A,Carninci P,Hayatsu N,Hirozane-Kishikawa T,Konno H,Nakamura M,Sakazume N,Sato K,Shiraki T,Waki K,Kawai J,Aizawa K,Arakawa T,Fukuda S,Hara A,Hashizume W,Imotani K,Ishii Y,Itoh M,Kagawa I,Miyazaki A,Sakai K,Sasaki D,Shibata K,Shinagawa A,Yasunishi A,Yoshino M,Waterston R,Lander ES,Rogers J,Birney E,Hayashizaki Y, , Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002();420(6915):563-73 PUBMED
Kawai J,Shinagawa A,Shibata K,Yoshino M,Itoh M,Ishii Y,Arakawa T,Hara A,Fukunishi Y,Konno H,Adachi J,Fukuda S,Aizawa K,Izawa M,Nishi K,Kiyosawa H,Kondo S,Yamanaka I,Saito T,Okazaki Y,Gojobori T,Bono H,Kasukawa T,Saito R,Kadota K,Matsuda H,Ashburner M,Batalov S,Casavant T,Fleischmann W,Gaasterland T,Gissi C,King B,Kochiwa H,Kuehl P,Lewis S,Matsuo Y,Nikaido I,Pesole G,Quackenbush J,Schriml LM,Staubli F,Suzuki R,Tomita M,Wagner L,Washio T,Sakai K,Okido T,Furuno M,Aono H,Baldarelli R,Barsh G,Blake J,Boffelli D,Bojunga N,Carninci P,de Bonaldo MF,Brownstein MJ,Bult C,Fletcher C,Fujita M,Gariboldi M,Gustincich S,Hill D,Hofmann M,Hume DA,Kamiya M,Lee NH,Lyons P,Marchionni L,Mashima J,Mazzarelli J,Mombaerts P,Nordone P,Ring B,Ringwald M,Rodriguez I,Sakamoto N,Sasaki H,Sato K,Schönbach C,Seya T,Shibata Y,Storch KF,Suzuki H,Toyo-oka K,Wang KH,Weitz C,Whittaker C,Wilming L,Wynshaw-Boris A,Yoshida K,Hasegawa Y,Kawaji H,Kohtsuki S,Hayashizaki Y, Functional annotation of a full-length mouse cDNA collection. Nature. 2001();409(6821):685-90 PUBMED

Uniparental Duplication	ProxBkpt	DisBkpt	Effects
MatDp(prox6) centromere to A3.2	cent	T77H	early embryonic lethality
Region References
Beechey CV A reassessment of imprinting regions and phenotypes on mouse chromosome 6: Nap1l5 locates within the currently defined sub-proximal imprinting region. Cytogenetic and genome research. 2004();107(1-2):108-14 PUBMED
Beechey CV Peg1/Mest locates distal to the currently defined imprinting region on mouse proximal chromosome 6 and identifies a new imprinting region affecting growth. Cytogenetics and cell genetics. 2000();90(3-4):309-14 PUBMED

Allele Symbol	Allele Name		MGI ID	ENSEMBL	REFSEQ
Ppp1r9a<tm1Lex>	targeted mutation 1, Lexicon Genetics		MGI:3528920	ENSEMBL	NM_181595