AllEmbryo onlySperm onlyCre onlyTet only
| Strain Name | Gene/Allele Symbol | Chr | Phenotype | Availability |
|---|---|---|---|---|
| B6J.129-Kcnj16<tm1Sj tu>/H | Kcnj16 | 11 | Disrupted Kir 5.1 Potassium Channel. Phenotype not known at this point. | Order |
| 102/H | Wild type, inbred strain. | Order | ||
| 10Bob | Affected mice head-bob, circle and walk backwards. | Order | ||
| 129S9/SvEvH-Nodal<tm 1Rob>/H | Nodal<tm1Rob> | 10 | Heterozygote viable. Homozygote early developmental lethal (does not gastrulate). | Order |
| 129S/SvEvNimrH | Inbred strain. | Order | ||
| 129S9/SvEvH | Wildtype. | Order | ||
| 129-Fgfr3<tm1.1Aomw> /Aomw | Fgfr3<tm1.1Aomw> | 5 | All homozygous males, some homozygous females and some heterozygous males develop an abnormal skull phenotype sometimes with malocclusion, and may be smaller in size. The phenotype is not fully penetrant. Refer to publication for further information: PMID:19086028. | Order From EMMA |
| A.129P2-Nat2<tm1Esim >/H | Nat2<tm1Esim> | 8 | No overt phenotype. | Order From EMMA |
| B6;129P2-Adcyap1r1<t m1Dgen>/H | Adcyap1r1 | 6 | No visible phenotype. | Order From EMMA |
| C3H.Cg-Fbxl3<Afh>/H | Fbxl3<Afh> | 14 | Identified in circadian rhythm screen. Mutants have a long circadian period 24.23hr (a) and 24.12hr (b). | Order From EMMA |
| Tg(DSPMKP3)Ox(Albert ) | Order | |||
| Ananisi | An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. | Order From EMMA | ||
| Anaya | An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. | Order From EMMA | ||
| Andromeda | An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. | Order From EMMA | ||
| TgN(DSPMKP3)Ox(Angel a) | Order | |||
| Ann Boleyn | Anb | UN | Heterozygotes have polydactyly of the hind limbs. Homozygotes have polydactyly of all four limbs. | Order |
| TgN(DSPMKP3)Ox(Annek a) | Order | |||
| Antonia | An ENU-induced mutation causing heritable anti-nuclear antibodies and variable proliferative and membranous glomerulonephritis with partial dominant phenotype and penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry and immunoglobulin levels. | Order From EMMA | ||
| C57BL/6J-Apc<Min>/5H | Apc<Min> | 18 | Mice develop life-shortening intestinal polyposis. | Order From EMMA |
| C57BL/6J-Apc<Min>/2H | Apc<Min> | 18 | (adenoma - anaemia) multiple intestinal neoplasia. | Order From EMMA |
| ApoE/PAI-1 | Apoe<tm1Bres> | 7 | Shortened life span. | Order From EMMA |
| ApoE/PLGN | Apoe<tm1Bres> | 7 | Rectal prolapse. Shortened life span in homozygotes. | Order From EMMA |
| 129(B6)-Apoe<tm1Bres >Plat<tm1Mlg>/H | Apoe<tm1Bres> | 7 | None. | Order From EMMA |
| Plat<tm1Mlg> | 8 | |||
| apoE tTg | Apoe<tm1Bres> | 7 | None. | Order From EMMA |
| Tgm2<tm1Gml> | 2 | |||
| Ariel | Hind limb paralysis from day 12 in homozygotes. | Order | ||
| C3H;C-Pde6b<atrd1>/H | Pde6b<atrd1> | 5 | Eyes-slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<atrd2>/H | Pde6b<atrd2> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<atrd3>/H | Pde6b<atrd3> | 5 | Eyes- slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<rd1-2H>/ H | Pde6b<rd1-2H> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<rd1-3H>/ H | Pde6b<rd1-3H> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<rd1-4H>/ H | Pde6b<rd1-4H> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| B10ScSn.BXSB-(D1Mit3 -D1Mit320) Chr Y<BXSB/MpJ>/BjmjrH | Enhanced autoantibody spectrum and titre. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit3 -D1Mit235) Chr Y<BXSB/MpJ>/BjmjrH | Enhanced autoantibody spectrum and titre. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit1 23-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH | Enhanced autoantibody spectrum and titre. Glomerulonephritis susceptibility. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit2 35-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH | Glomerulonephritis susceptibility. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit3 03-D1Mit305) Chr Y<BXSB/MpJ>/BjmjrH | Glomerulonephritis susceptibility. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit3 3-D1Mit223) Chr Y<BXSB/MpJ>/BjmjrH | ANA, 75% mortality, enhanced autoantibody titre, severe glomerulonephritis. | Order From EMMA | ||
| B6;D2-Tg(Sycp1-cre)4 Min/J | Tg(Sycp1-cre)4Min | UN | None given. | Order |
| C.Cg-Il1rn<tm1Nick>/ Nick | Il1rn<tm1Nick> | 2 | Strain sporadically and independently develops rheumatoid-like arthritis, localised psoriasis-like lesions and patchy transmural destructive arteritis of the elastic vessels. Hygiene dependent (negative correlation). Different strain dependence of each disease. This strain, our SPF lab, 80% affected (each disease independently) at 200 days. | Order From EMMA |
| C3H101H A/A<w>-Bbn/H | Bbn | UN | Affected animals are deaf and exhibit headbobbing and circling behaviour. | Order From EMMA |
| STOCK-Bhv26/H | The alternation score suggest this line has a potential short term working memory deficit. | Order From EMMA | ||
| BHV43 | Possible short-term working memory deficit indicated by reduced spontaneous alternation in the Y-maze. | Order From EMMA | ||
| C3H.Cg-Trpc3<Mwk>/H | Trpc3<Mwk> | 3 | Staggering, ataxic with limited movement in back legs. Heterozygotes are usually small. | Order From EMMA |
| C57BL/6J-blst/H | blst | UN | Spontaneous recessesive coat colour mutation - light grey coat colour. | Order From EMMA |
| C3H;C-Snap25<Bdr>/H | Snap25<Bdr> | 2 | Poor sight. Blind drunk. Small at weaning. SHIRPA anomalies including reduced or absent visual placing and staggering gait. Homozygotes have not been identified. | Order From EMMA |
| C57BL/6J-Blite/H | Blite | UN | White with non-agouti patches. Some patches reverting to non-agouti are visible in a small number of offspring. Timed matings of heterozygous stock can yield oedematous embryos. | Order From EMMA |
| BLUFF | Fluffy coat, abnormal hair distribution and texture. | Order | ||
| BMD2 | Low bone mineral density. | Order | ||
| B6NDen;B6N-Brpf1<tm1 a(EUCOMM)Wtsi>/H | Brpf1<tm1a(EUCOMM)Wt si> | 6 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| bv | bv | 5 | Bronx Waltzer. Recessive mutant; hyperactivity, circling, headbobbing and deafness in the homozygote. | Order |
| C3H/HeH | Order | |||
| C3H;C-Chd7<Todo>/H | Chd7<Todo> | 4 | Headweaving and circling in heterozygotes. Homozygotes die at mid gestation with vascular and brain defects. | Order From EMMA |
| C3H;C-Chd7<Edy>/H | Chd7<Edy> | 4 | Headweaving/circling. | Order From EMMA |
| B6.Cg-Il1rn<tm1Nick> /Nick | Il1rn<tm1Nick> | 2 | Strain resistant to arthritis, arteritis and psoriasis (seen in BALB/c) but highly susceptible to undefined 'malaise' under conventional conditions. | Order From EMMA |
| B6.129P2-Fgfr3<tm1.1 Aomw>/Aomw | Fgfr3<tm1.1Aomw> | 5 | All homozygous males, some homozygous females and some heterozygous males develop an abnormal skull phenotype sometimes with malocclusion, and may be smaller in size. The phenotype is not fully penetrant. | Order From EMMA |
| B6CB-Tg(ATXN3*)84.2C ce/H | Tg(ATXN3*)84.2Cce | UN | Slowly progressive cerebellar defecit from 4weeks of age; wide flattened gait, clasping of all 4 limbs, neuronal loss, gliosis & neuronal intranuclear inclusions present in the pons & cerebellum, peripheral nerve demyelination. | Order From EMMA |
| C57BL/6J-Ucp1<m1H>/H | Ucp1<m1H> | 8 | Homozygotes are unable to thermoregulate. | Order |
| TgN(UbiCFL)Ox(Calvin ) | Order | |||
| C3H;B6-Candy/H | Hyperglycaemia, glycosuria. Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| C3H;B6-Candy2/H | Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| C3H;B6-Candy3/H | Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| C3H;B6-Candy4/H | Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| C3H;B6-Candy5/H | Elevated plasma glucose and phosphate at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| B6;129P2-Capn1<tm1Dg en>/H | Capn1 | 19 | No overt phenotype | Order From EMMA |
| C3H.Cg-Casp3<I216F>/ H | Casp3 | 8 | Reduced apoptosis in homozygotes. Phenocopies Caspase 3 null alleles. | Order From EMMA |
| CCBAN3-2371 | Order | |||
| CCBAN4-2513 | Order | |||
| CCBAN4-2547 | Order | |||
| CEMO_S2 | Order | |||
| CEMO_S3 | Order | |||
| CEMO_S5 | Order | |||
| CHANGELING | Motor co-ordination problems & death before weaning age. | Order | ||
| TgN(UbiCFL)Ox(Chelse a) | Order | |||
| C3H101H-Flt4<Chy>/H | Flt4<Chy> | 11 | Milky abdomen shortly after birth. (abdomen, feet) chylous ascites. | Order From EMMA |
| CIRCA12 | Identified in circadian rhythm screen. Has a reduced period lengthening response when subjected to constant light conditions. | Order | ||
| CIRCA2 | Long activity under constant dark period. | Order | ||
| CIRCAD21 | Order | |||
| B6.Cg-Cited2<L247P>/ H | Cited2 | 10 | Although the amino acid change occurs in a highly conserved residue, the mutant is homozygous viable and fertile, with no detectable phenotype. In trans to the Knock-out allele, it is viable and phenotypically normal. | Order From EMMA |
| B6J.129-Cited2<tm2Bh a>/H | Cited2<tm2Bha> | 10 | Cre-mediated recombination throughout the entire epiblast of early embryos recapitulates the complete loss of function phenotype of Cited2, which include cardiac malformations, adrenal agenesis, fusion of cranial ganglia, abnormal cardiac neural crest migration, excencephaly and left right patterning defects. | Order From EMMA |
| TgN(UbiCFL)Ox(Cleo) | Order | |||
| STOCK Col4a1<Raw>/H | Col4a1<Raw> | 8 | Retinal ateriolar wiring. Shiny retinal blood vessels. | Order From EMMA |
| STOCK Col4a1<Svc>/H | Col4a1<Svc> | 8 | Small with vacuolar cataract. Also other eye abnormalities. Mutants are small and bruised at birth and tend to remain small throughout life. Variable eye findings, the most consistent of which is a vacuolar cataract. Other eye findings include enlarged eyes, corneal opacity, iris-corneal adhesions, iris-lens adhesions, retinal vascular abnormalities. | Order From EMMA |
| C3H;C-Gjb2<E119stop> /H | Gjb2<E119stop> | 14 | Homozygous lethal, heterozygotes appear as wildtypes. | Order |
| Connexin26<Har1> Wil d type | Homozygous lethal, heterozygotes appear as wildtypes. | Order | ||
| TgN(UbiCFL)Ox(Conrad ) | Order | |||
| STOCK Scrib<Crc>/H | Scrib<Crc> | 15 | Neural tube defects. | Order |
| CVBA 3'/Utrophin+/-/ mdx | CVBA 3'/Utrophin+/-/mdx mice are transgenic for the dystrophin cDNA with a deletion of exons 17-48 under the control of the MCK promoter. | Order From EMMA | ||
| C3H;C-Gjb2<I128V>/H | Gjb2<I128V> | 14 | Heterozygotes appear wildtype and show normal hearing. | Order From EMMA |
| C3H;C-Chd7<Cycn>/H | Chd7<Cycn> | 4 | Headbobbing/circling. Heterozygotes exhibit headweaving and circling behaviour. Homozygous foetuses exhibit midgestational lethality potentially due to vascular and/or anterior neural tube defects. | Order From EMMA |
| C3H;C-Dfp2/H | Dfp2 | 4 | Heterozygotes have dark pigmentation on footpads and additional areas such as tail, ears etc. | Order From EMMA |
| C3H101H-Dbf/H | Dbf | 1 | Many extra toes on all feet. Homozygote lethal. Dominant, digits - number, limbs - bones, size - small, reduced viability, skull, sterility, cerebrospinal fluid?? | Order From EMMA |
| C3H101H-Del(13)36H | Order | |||
| 129P2/OlaHsd-Tpcn2<G t(YHD437)Byg>/H | Tpcn2<Gt(YHD437)Byg> | 7 | Order | |
| C3H;C-Dilp3/H | Dilp3 | UN | Dilated pupils. | Order From EMMA |
| C3H;C-Dilp4/H | Dilp4 | UN | Mice carrying this mutation have permanently dilated pupils. | Order From EMMA |
| STOCK Tmc1<dn> | Tmc1<dn> | 19 | Deafness. | Order From EMMA |
| B6;129P2-Esr2<tm1Dge n>/H | Esr2 | 12 | No visible phenotype. | Order From EMMA |
| 129S9/SvEvH-Evta/H | Evta | UN | White coat with non-agouti specking and occasional non-agouti patches. | Order From EMMA |
| B6NDen;B6N-Slc38a10< tm2a(EUCOMM)Wtsi>/H | Slc38a10<tm2a(EUCOMM )Wtsi> | 11 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| TgN(FLU)Ox(Fergie) | Order | |||
| TgN(FLU)Ox(Fiona) | Order | |||
| FMLC-TM/12 | Statistically elevated levels of leptin & adiponectin after overnight fasted bleeds at 12wks of age with increased bodyweight. Bodyweight & adiponectin levels still elevated after an overnight fasted bleed at 16wks of age. After DEXA analysis: statistically increased bodyweight, fat mass & % body fat. | Order | ||
| C3H;C-Gsdma3<Fgn>/H | Gsdma3<Fgn> | 11 | Mice carrying this mutation show progressive hair loss. Weanlings show a typical ragged coat phenotype. Following this mice go through several cycles of hair loss and regrowth. Adult mice eventually become almost hairless with a small amount of hair around the snout. | Order From EMMA |
| FNOS2 | Circling, vestibular defects. Heterozygotes can be identified by mild head bobbing or circling behaviour. Mice with this behaviour usually show morphological changes in the inner ear. | Order From EMMA | ||
| Fragal (CEMO_A1) | Order | |||
| TgN(FLU)Ox(Freddie) | Order From EMMA | |||
| FTO-I367F | Fto<I367F> | 8 | Order | |
| FTOKOB8-B6-ACTIN-FLP E | Order | |||
| funny feet | Small, abnormal limbs (short and stick like). | Order | ||
| G6pd<b> | Low activity of glucose 6 phosphate dehydrogenase. | Order | ||
| B6;129P2-Galr2<tm1Dg en>/H | Galr2<tm1Dgen> | 11 | No visible phenotype. | Order From EMMA |
| Galr2 | 11 | |||
| TgN(UminiG)Ox(Gareth ) | Order | |||
| C3H.Cg-Gars<C201R>/H | Gars<C201R> | 6 | Mice heterozygous for this dominant mutation exhibit low limb tone, low grip strength and poor wire manoeuvrability. | Order From EMMA |
| TgN(UminiG)Ox(Gavin) | Order | |||
| C3H;C-GENA381/H | High Alkaline phosphatase, low cholesterols, distinguishable by blood testing. Some mutants are smaller and have a darker coat colour. | Order From EMMA | ||
| C3H;C-GENA111/H | Small at birth and weaning. Waddler behaviour. Rough coat. | Order From EMMA | ||
| C3H;C-GENA187/H | High locomotive activity and arousal activity in heterozygotes. | Order From EMMA | ||
| C3H;C-Tuba1a<Jna>/H | Tuba1a<Jna> | 15 | Behavioural. High locomotor activity (LMA). Heterozygotes are detected by measuring beam-splitting activity in LMA cages. Homozygosity has not been tested. GENA227 exhibits spontaneous hyperactivity in the absence of deafness and circling. | Order From EMMA |
| C3H;C-GENA316/H | GENA316/+ animals have poor rota rod performance. | Order From EMMA | ||
| C3H;C-GENA323/H | Large body size (+125%) and flaccid abdonimal tone. | Order From EMMA | ||
| C3H.Cg-GENA339/H | Mice heterozygous for this mutation have cranofacial abnormalities observed as a broad head. | Order From EMMA | ||
| C3H;C-GENA344/H | High pelvic elevation. | Order From EMMA | ||
| C3H;C-GENA353/H | GENA353/+ animals have no response to touch escape. | Order From EMMA | ||
| C3H;C-GENA357/H | Intermittent fits and marked resting tremor. | Order From EMMA | ||
| C3H;C-GENA360/H | Low total choloesterol and HDL cholesterol. | Order From EMMA | ||
| C3H;C-Pmp22<Tr-3H>/H | Pmp22<Tr-3H> | 11 | Fits and marked resting tremors. Mice heterozygous for this mutation exhibit hypomyelination abnormalities and have a marked resting tremor. | Order From EMMA |
| C3H;C-GENA377/H | Heterozygote animals fall off the rota rod. | Order From EMMA | ||
| C3H;C-GENA396/H | Mice heterozygous for this mutation have high blood glucose concentrations (hyperglycaemia). | Order From EMMA | ||
| C3H;C-GENA397/H | Hypoglycaemic. | Order From EMMA | ||
| C3H.C-Scn8a<Clth>/H | Scn8a<Clth> | 15 | Cloth-ears mice show reduced acoustic startle response and mild hearing loss from about 30 days old. Tests indicate that the peripheral neural auditory pathway is impaired in these mutants, but that cochlear function is normal. Both homozygotes and heterozygotes display paroxysmal tremor episodes with behavioural arrest. Homozygotes demonstrate a milder continuous tremor during movement and rest. | Order From EMMA |
| C3H;C-GENA401/H | Mice carrying this mutation display late onset deafness after 6 months of age. Suspected homozygotes also show circling/deaf/headbobbing/hyperactive behaviour. | Order From EMMA | ||
| C3H.Cg-GENA100/H | Mice carrying this mutation have dark pigmentation on their footpads and additional areas such as the ears and tail. Some litter mates may also be small. | Order From EMMA | ||
| C3H.Cg-GENA115/H | Small at birth and weaning. Small testis. | Order From EMMA | ||
| GENA119 | circling. | Order | ||
| B6J.Cg-Bfc/H | Short domed head. | Order | ||
| C3H.Cg-Bfc/H | Bfc | 9 | Short broad head, dark pigmentation, abnormal gait and plevic elevation. Mice heterozygous for this mutation have abnormal facial pigmentation, cranofacial abnormalities observed as broad head and skeletal abnormalities observed as an abnormal gait and elevated pelvis. | Order From EMMA |
| C.Cg-Bfc/H | Bfc | 9 | Short broad head, dark pigmentation, abnormal gait and plevic elevation. Mice heterozygous for this mutation have abnormal facial pigmentation, cranofacial abnormalities observed as broad head and skeletal abnormalities observed as an abnormal gait and elevated pelvis. | Order |
| C3H;C-GENA127/H | Heterozygotes have a pigmentation defect where the coat is lighter than agouti. | Order From EMMA | ||
| C3H.Cg-GENA135/H | Mice carrying this mutation have an abnormal gait (hunched, jerky, darting), tail rattle, evidence of aggression in arena, vigourous touch escape response and tachycardia. | Order From EMMA | ||
| GENA140 | Small with short head. | Order | ||
| C3H.Cg-GENA143/H | Abnormal gait and waddling movement. | Order From EMMA | ||
| GENA144 | Passive. | Order | ||
| GENA15 | Small, extra digit. | Order | ||
| GENA151 | High activity. | Order | ||
| C3H.Cg-GENA155/H | Heterozygotes are small with elevated pelvic limbs. | Order From EMMA | ||
| C3H;C-GENA160/H | Head shaking , belly spot, white toes. | Order From EMMA | ||
| C3H.Cg-GENA172/H | GENA172/+ animals have white feet and a belly spot. | Order From EMMA | ||
| GENA185 | Dominant behavoiural mutant with high gait, balance problems and strong grip. | Order | ||
| C3H;C-Icst/H | Icst | 2 | Abnormal gait and iris corneal strands. | Order From EMMA |
| C3H.Cg-GENA200/H | Heterozygotes have a reduced or absent toe pinch response and/or reduced grip strength in SHIRPA assessment. | Order From EMMA | ||
| GENA203/mod | GENA203 mod/+ have an extra digit on one hind limb. GENA203 mod/Spgl have extra digits on all four limbs. Both have bone abnormalities. | Order | ||
| GENA214 | Very active, circling, limb grasp, no toe pinch. | Order | ||
| GENA217 | Low ppi. | Order | ||
| C3H;C-GENA228/H | Headweaving and circling in heterozygotes. | Order From EMMA | ||
| C3H;C-GENA243/H | Low Total and HDL cholesterol. | Order From EMMA | ||
| C3H;C-GENA26/H | Low muscle tone, belly spot, white feet, short crinkly tail. | Order From EMMA | ||
| C3H.Cg-GENA313/H | Heterozygote animals have a poor righting reflex and also have a small body size. | Order From EMMA | ||
| C3H;C-GENA318/H | Irritable at SHIRPA test, kinky tail, high locomotive activity. | Order From EMMA | ||
| C3H.Cg-GENA321/H | High Startle. Heterozygotes are detected by measuring response to 110 db tones. They are hyper responsive to sudden pulses of sound. The underlying cause may be neurological or behavioural. Homozygosity has not been tested to date. | Order From EMMA | ||
| GENA342 | Headweaving/headbobbing and circling in heterozygotes. | Order | ||
| C3H;C-Gck<Gena348>/H | Gck<Gena348> | 11 | Mice heterozygous for this mutation have high blood glucose and increased body weight. | Order From EMMA |
| C3H.Cg-GENA350/H | Abnormal gait, vigorous touch escape. | Order From EMMA | ||
| C3H.Cg-GENA359/H | GENA359/+ animals have a lower left eye, blunt nose, craniofacial defect. | Order From EMMA | ||
| C3H;C-GENA382/H | Animals from this stock have abnormally high levels of alanine transferase (ALT) and asparate tansferase (AST). | Order | ||
| C3H;C-GENA391/H | Lipid and glucose perturbations. | Order From EMMA | ||
| C3H;C-Rasgrf1<enu1H> /H | Rasgrf1<enu1H> | 9 | Small mice when inherited through an affected male-imprinting mutation. | Order From EMMA |
| C3H;C-GENA91/H | Tremor. | Order From EMMA | ||
| C3H.Cg-Sho2/H | Sho2 | UN | GENA93 animals have cranofacial abnormalities observed as shorthead. | Order From EMMA |
| TgN(UminiG)Ox(George ) | Order | |||
| TgN(UminiG)Ox(Gerald ) | Order | |||
| TgN(UminiG)Ox(Gordon ) | Order | |||
| TgN(UminiG)Ox(Grant) | Order | |||
| B6NDen;B6N-Snip1<tm1 a(EUCOMM)Wtsi>/H | Snip1<tm1a(EUCOMM)Wt si> | 4 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| B6;129P2-Grm1<tm1Dge n>/H | Grm1 | 10 | No visible phenotype. | Order From EMMA |
| B6;129P2-Grm4<tm1Dge n>/H | Grm4 | 17 | No visible phenotype. | Order From EMMA |
| B6;129P2-Grm5<tm1Dge n>/H | Grm5 | 7 | No visible phenotype | Order From EMMA |
| B6;129P2-Grm8<tm1Dge n>/H | Grm8 | 6 | No visible phenotype | Order From EMMA |
| B6J;C-Guth/H | Huntington’s disease, enhancer of tremor onset. | Order | ||
| Hoxa3<tm1(cre)Moon> | Hoxa3<tm1(cre)Moon> | 6 | Order | |
| HSP27 WT High Copy L ine | No phenotype in transgenic carriers. | Order From EMMA | ||
| HSP27 WT Low Copy Li ne | No phenotype in transgenic carriers. | Order From EMMA | ||
| HSP27 WT PrP Promote r Line | No phenotype in transgenic carriers | Order From EMMA | ||
| B6NDen;B6N-Tnfaip1<t m1a(EUCOMM)Wtsi>/H | Tnfaip1<tm1a(EUCOMM) Wtsi> | 11 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| Igfn1_KD1 | Order | |||
| B6;129P2-Il8ra<tm1Dg en>/H | Cxcr1<tm1Dgen> | 1 | No visible phenotype. | Order From EMMA |
| B6NDen;B6N-Cyb561<tm 1a(EUCOMM)Wtsi>/H | Cyb561<tm1a(EUCOMM)W tsi> | 11 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| INH/17 | Trembler mutation with high stepping gait. | Order From EMMA | ||
| INH/18 | Trembler mutation with high stepping gait. | Order From EMMA | ||
| INH/6 | Heterozygous females are striped. Hemizygous males have no guard hairs, hair on tails, normal teeth, very little hair behind the ears. Homozygous females look like hemizygous males. | Order From EMMA | ||
| INH/8 | Trembler mutation (poor inheritance). | Order From EMMA | ||
| Isl1<tm1(cre)Cos> | Isl1<tm1(cre)Cos> | 13 | Order | |
| Isl1<tm1(cre)Sev> | Isl1<tm1(cre)Sev> | 13 | Order | |
| STOCK Dnahc11<iv>/H | Dnahc11<iv> | 12 | Situs inversus viscerum. | Order From EMMA |
| C3H.Cg-Fbxo11<Jf>/H | Fbxo11<Jf> | 17 | Deaf. | Order From EMMA |
| 129P2/OlaHsd-Map3k1< Gt(YTC001)Byg>/H | Map3k1 | 13 | Full description available from Europhenome | Order |
| C3H.Cg-Mecom<Jbo>/H | Mecom<Jbo> | 3 | Late onset deafness, extra digit, reduced body weight, craniofacial defect. | Order From EMMA |
| K10T+/- | Krt10<tm1Tmm> | 11 | K10T mice show a phenotype in the epidermis and in tongue, esophagus and forestomach. Homozygous pups die on the first day after birth from dehydration due to generalised blistering within the epidermis. Heterozygous mice look normal at birth and develop a progressive thickening of the skin and hyperkeratosis. Their skin is scaly. Heterozygotes breed normally. | Order From EMMA |
| B6;129P2-Kcnj15<tm1D gen>/H | Kcnj15 | 16 | Kir4.2 potassium channel knockout. Phenotype as yet undetermined | Order From EMMA |
| Khk-a<tm1.1Ls> | No visible phenotype. | Order | ||
| Khk-N<tm1(neo)Ls> | Order | |||
| C3H.Cg-Kit<W-e>/H | Kit<W-e> | 5 | Heterozygotes have coat spots. Homozygosity is lethal. | Order From EMMA |
| C3H;C-Kit<W-39H> | Kit<W-39H> | 5 | Heterozygotes have a white belly spot and occasionally a white head blaze. Homozygotes have not been identified and they may die in utero | Order |
| B6NDen;B6N-Fam117b<t m1a(EUCOMM)Wtsi>/H | Fam117b<tm1a(EUCOMM) Wtsi> | 1 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| C3H;C-Lcl/H | Lcl | UN | Lens cloudy. Cataracts. Mice heterozygous for this mutation show progressive cataract formation, with total opacity at approximately 3 months. Mice homozygous for this mutation have small eyes and total lens opacity at 4-5 weeks. | Order From EMMA |
| C3H;C-Pax6<Leca3>/H | Pax6<Leca3> | 2 | Mutants may have central corneal opacity, small eyes, dilated pupils and lens-corneal adhesion. | Order From EMMA |
| LMWP3 | Low Molecular Weight Protein (LMWP) in the urine which is an indicator of proximal tubule dysfunction in the kidney. | Order | ||
| Lnk -/- | Order | |||
| Lo Moe | None. | Order From EMMA | ||
| C3H;B6-Lpk/H | Lpk | UN | Short limbs (achondroplasia). | Order From EMMA |
| C.Cg-Lpk/H | Lpk | UN | Short-limbed phenotype in both fore- and to a lesser extent hind-limbs. Mice have short limbs (achondroplasia). | Order |
| B6;129P2-Lphn2<tm1Dg en>/H | Lphn2 | 3 | None | Order From EMMA |
| B6NDen;B6N-Ttll4<tm1 a(EUCOMM)Wtsi>/H | Ttll4<tm1a(EUCOMM)Wt si> | 1 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| C3H101H-Maf<Ofl>/H | Maf<Ofl> | 8 | Order From EMMA | |
| 129P2/OlaHsd-Mkrn1<G t(RRB087)Byg>/H | Mkrn1<Gt(RRB087)Byg> | 6 | No abnormal phenotype detected. | Order |
| TgN(DSPM36)1886OxAna t | Order | |||
| TgN(DSPM36)1892OxAna t | Order | |||
| MBT1 | Lack of marble burying. Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. | Order From EMMA | ||
| MBT2 | Low anxiety, marble mutant | Order From EMMA | ||
| MBT3 | Low anxiety, marble mutant. | Order From EMMA | ||
| MBTR2 | Lack of marble burying. | Order From EMMA | ||
| MBTR3 | Lack of marble burying. | Order From EMMA | ||
| B6;129P2-Mc2r<tm1Dge n>/H | Mc2r | 18 | No visible phenotype. | Order From EMMA |
| MCA/mdx | Order From EMMA | |||
| B;CBACa-Dmd<mdx>Tg(C KMM-tTA)A3Rhvh/H | Tg(CKMM-tTA)A3Rhvh | UN | MCK-tTA/mdx mice contain the muscle specific creatine kinase (MCK) promoter driving the tetracycline regulated transactivator (tTA). | Order From EMMA |
| Dmd<mdx> | X | |||
| Mesp1<tm2(cre)Ysa> | Mesp1<tm2(cre)Ysa> | 7 | Order | |
| GENA163 | Mitf<Mi-H> | UN | Microphthalmia. Dominant mutant with small eyes, Mi-like. Heterozygotes are paler, they have head and belly spots. Homozygotes are white with no eyes. | Order |
| MLO | c<62chH>/c<62chH> homozygotes have a grey coat colour, c/c<62chH> trans-heterozygotes have a cream coat colour and ruby coloured eyes. | Order From EMMA | ||
| MOD Fused Toes | Syndactyly | Order | ||
| TgN(DSPM36)1892OxAna t | Order | |||
| C3H;C-Mtu/H | Mtu | 12 | Kinky tail, deaf, belly spot. Heterozygotes exhibit abnormal tail morphology, are deaf, and have belly spots that are characteristic of neural crest defects. Homozygotes, do not appear to be viable, as they have an open neural tube. | Order From EMMA |
| TgN(DSPM36)1327OxAna t | Order | |||
| MURB125 | Limbs and bones are shorter than normal | Order | ||
| MURB151 | Heterozygotes have light grey coat , darker grey points on ears, nose and tail. Can be classified at 2-3 days old as the pigmentation of the skin is visibly different. | Order | ||
| SPRET/EiJH | Order | |||
| C3H101H-Mut1602/H | Small at birth and weaning with white hind feet, short tail and head bobbing. Mice have shorter kinky tails. They have waltzing/head bobbing behaviour. Some are small in size and have white feet. | Order From EMMA | ||
| C3H101H-Mut1679/H | Mice are small at birth and weaning. They have white feet, shorter kinky tails. Some have domed heads i.e skeletal effects and some display behavioural abnormalities i.e head bobbing. Occasional nasal cleft. | Order | ||
| C3H101H-Mut1704/H | Small at birth and weaning. Domed/pointy heads, some with fused toes.The original female was small at birth and weaning with fused hind toes, slightly domed head, whitish toes and tail tip. The offspring phenotype varied, many were small, the fusing of toes only involved the soft tissue not bone. These embryos were generated by IVF with MUT/1704.3d male; small with kink in tail at birth. Small and runty at weaning with dark coat, pointy face and closed eyes. | Order | ||
| MUTN212 | Circling, limb grasp & trunk curl. | Order | ||
| MUTN673 | Small, deaf. | Order | ||
| MUTN777 | Right eye missing, very active, circling | Order | ||
| MUTN873 | Small, deep set eyes, short face, nose bends to left, upper teeth bent back, nose crooked, hunched, high gait & pelvic elevation, no abdominal tone, slow heart rate. | Order | ||
| MUTS 1/14 | Small eye mutation | Order From EMMA | ||
| Myl2<tm1(cre)Krc> | Myl2<tm1(cre)Krc> | 5 | Order | |
| Myo7a<sh1-9J> | Myo7a<sh1-9J> | 7 | Shaker. | Order |
| CBB8-Myo7a<26SB>/H | Myo7a<26SB> | 7 | Shaker 1 allele. Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wildtypes are indistinguishable from each other. Homozygotes show no preyer reflex. These Myo7a mutants do have severe hearing and vestibular abnormalities. While their retinas do not show any anatomical degeneration, there have been reports of retinal abnormalities. | Order From EMMA |
| CBB8-Myo7a<3336SB> | Myo7a<3336SB> | 7 | Shaker. | Order From EMMA |
| Myo7a<4494SB> | Myo7a<4494SB> | 7 | shaker | Order From EMMA |
| Myo7a<sh1-6J> | Myo7a<sh1-6J> | 7 | Shaker. | Order |
| Myo7a<sh1-8165SB> | Myo7a<sh1-8165SB> | UN | shaker. Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wildtypes are indistinguishable from each other. Homozygotes show no preyer reflex. Homozygote females will not rear litters | Order |
| Myo7a<Sh1-816SB> | Myo7a<816SB> | 7 | Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wild types are not distinguishable from each other. Homozygotes show no preyer reflex | Order From EMMA |
| Myo7a<sh1> | Myo7a<sh1> | 7 | shaker | Order |
| TgN(DSPM36)1668OxAna t | Order | |||
| B6;129-Scn10a<tm3(cr e/ERT2)Jnw>/H | Scn10a<tm3(cre/ERT2) Jnw> | 9 | None observed (heterozygous Nav1.8-CreERT2 can express enough Cre to delete the floxed fragement, but it does not affect the expression of Nav1.8 in Nav1.8 positive neurons in DRG). | Order From EMMA |
| B6;129P2-Nek6<tm1Dge n>/H | Nek6 | 2 | No visible phenotype. | Order From EMMA |
| Nephertiti | No visible phenotype. Mice develop nephrotic range proteinuria at a young age and has abnormal liver histology, similar to Lafora body disease. | Order From EMMA | ||
| B6NDen;B6N-Nipsnap1< tm1a(EUCOMM)Wtsi>/H | Nipsnap1<tm1a(EUCOMM )Wtsi> | 11 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| Nkx2-5<tm1(cre)Rjs> | Nkx2-5<tm1(cre)Rjs> | 17 | Order | |
| NPA31-B4 | Offspring inheriting the targeted construct paternally do not feed, are hypoactive and die within a few hours. | Order | ||
| B6;129P2-Npy6r<tm1Dg en>/H | Npy6r | 18 | No visible phenotype. | Order From EMMA |
| B6;129P2-Nr1d2<tm1Dg en>/H | Nr1d2 | 14 | No visible phenotype. | Order From EMMA |
| C3H101H-Gnas<Oedsml> /H | Gnas<Oedsml> | 2 | When inherited through the female, the offspring are oedematous. When inherited through the male, the offspring show postnatal growth retardation. | Order |
| STOCK Opdc/H | Opdc | 19 | Optic disc coloboma. Mutants have retinal vascular abnormalities and optic discs of unusual size. | Order From EMMA |
| B6NDen;B6N-Orc5l<tm1 a(EUCOMM)Wtsi>/H | Orc5l<tm1a(EUCOMM)Wt si> | 5 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| C.Cg-ostes/H | ostes | UN | Small with muscle tremor. | Order |
| B6;129P2-P2rx6<tm1Dg en>/H | P2rx6 | 16 | No visible phenotype. | Order From EMMA |
| B6NDen;B6N-Pa2g4<tm1 a(EUCOMM)Wtsi>/H | Pa2g4<tm1a(EUCOMM)Wt si> | 10 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| C3H;C-Pax6<Leca4>/H | Pax6<Leca4> | 2 | Mutants have small eyes, but not always corneal opacity (corneal opacity affects most other Pax6 mutants). Often have anterior cataract. | Order From EMMA |
| Pax6<Sey-Neu> | Pax6<Sey-Neu> | 2 | Small eye | Order |
| B6;129P2-Pde2a<tm1Dg en>/H | Pde2a | 7 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde3a<tm1Dg en>/H | Pde3a | 6 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde4b<tm1Dg en>/H | Pde4b | 4 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde4d<tm1Dg en>/H | Pde4d | 13 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde8a<tm1Dg en>/H | Pde8a<tm1Dgen> | 7 | No visible phenotype. | Order From EMMA |
| PED-JP/16 | Order | |||
| PEDM/105 | Elevated plasma phosphate. | Order | ||
| PEDM/14 | Hyperglycaemia. Elevated plasma glucose at 16 and 24 weeks of age. No detection of glucose in the urine. | Order From EMMA | ||
| PEDM/15 | High anxiety, tremors, small at weaning. | Order From EMMA | ||
| PEDM/25 | This strain demonstrates late onset (>6 months of age) tremors and some individuals have a high nose-poking response in a behavioural test. | Order From EMMA | ||
| PEDM/29 | Highly active and demonstrates a high degree of anxiety | Order From EMMA | ||
| PEDM/35 | Hyperglycaemia and glycosuria. | Order From EMMA | ||
| PEDM/36 | Limb grasping, walks backwards, inactive | Order From EMMA | ||
| PEDM/41 | Deformed digits shortened limbs | Order From EMMA | ||
| PEDM/42 | Homozygotes have a belted white band of hair around the mouse middle. Their appearance is similar to that of the known mutation on Chromosome 15, Adamts20<bt> (Belted). | Order From EMMA | ||
| PEDM52 | Presumed homozygotes have spina bifida. | Order | ||
| PEDM/83 | Short/long faces and small mis-shapen eye sockets. | Order | ||
| PEDV/118 | Order | |||
| PEDV/119 | Order | |||
| PEDV/128 | Order | |||
| PEDV/146 | Dark skin in marble like patterns, slightly darker fur. | Order | ||
| PEDV/156 | Headbob & head tilt. | Order | ||
| PKDBac Line2 | Hets appear normal. Homs are small and develop hind-limb dragging at 4-6 weeks old | Order | ||
| C3H;C-Play50/H | Play50 | UN | Identified in circadian rhythm screen. Reduced bouts of wheel- running activity | Order From EMMA |
| C3H;C-Play63/H | Reduced bouts of wheel- running activity. | Order From EMMA | ||
| C3H.Cg-Play1/H | These mice have a higher than normal degree of daytime activity in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play16/H | No entrainment response to light pulses given at CT16. | Order From EMMA | ||
| C3C-Play19/H | Identified in circadian rhythm screen. Potentially no entrainment response to light pulses given at CT16 | Order From EMMA | ||
| C3H.Cg-Play22/H | Play22 | UN | Mice carrying this mutation show a low endurance of wheel running activity. Wheel running activity is about 10% of control animals. | Order From EMMA |
| C3H.Cg-Play31/H | Identified in a circadian rhythm screen. Wheel turning activity is dramatically reduced in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play32/H | Identified in a circadian rhythm screen. These mice have reduced bouts of wheel running activity in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play40/H | Identified in circadian rhythm screen. Mutants have potentially no entrainment response to light. | Order From EMMA | ||
| C3H;C-Play42/H | Identified in a circadian rhythm screen. These mice have two sets of activity onsets when first exposed to constant darkness conditions. | Order From EMMA | ||
| C3H;C-Play44/H | Identified in circadian rhythm screen. Potentially shows a large entrainment response to light and phase advancement in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play46/H | Play46 | UN | Poor entrainment to light in 12:12 light dark: cycle. | Order From EMMA |
| C3H;C-Play47/H | Identified in circadian rhythm screen. These mice free run in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play65/H | Changed period length after light pulse at CT16. | Order From EMMA | ||
| C3H;C-Play72/H | Reduced bouts of wheel running activity. | Order From EMMA | ||
| C3H;C-Play78/H | Potentially no entrainment response to light. | Order From EMMA | ||
| C3H;C-Play79/H | Poor entrainment response to light. | Order From EMMA | ||
| C3H;C-Play81/H | Long circadian period & poor entrainment response | Order From EMMA | ||
| C3H;C-Play82/H | This mutation was identified in a circadian rhythm screen. It shows reduced bouts of wheel-running activity. | Order From EMMA | ||
| C3H;C-GENA300/H | Late onset deafness. | Order From EMMA | ||
| POMC-Cre | Order | |||
| Pomc-cre Z/EG | Order | |||
| C3H101H-Wnt7a<px>/H | Wnt7a<px> | 6 | Sterility. Skeletal abnormalities, mainly forelimb abnormalities. Postaxial hemimelia, recessive. The forelimbs are regularly affected. There may be absence of digits 5, 4, and 3, & reduction or absence of the ulna. There is always a large oval foramen in the scapula. The hindlimbs are usually normal, but digit 5 may be absent, and occasionally the fibula is reduced. Mice with severally affected limbs tend to have an extra pair of ribs and a slight reduction in number of presacral vertebrae. Both sexes are sterile and show anomalies of the Mullerian ducts, including a partly or wholly double vagina and uncoiled oviducts in the female, and peristent Mullerian ducts in the male. | Order From EMMA |
| Quaver | Tremors. | Order | ||
| C3H;C-Rasgrf1<enu2H> /H | Rasgrf1<enu2H> | 9 | Small. | Order From EMMA |
| C3H;C-Rky/H | Rky | UN | At 10 weeks of age, pups show a swim phenotype described as rocky, leaning and jerky. By 18 weeks of age mice develop a head-bobbing/circling cage phenotype. | Order From EMMA |
| REC/9 | Weak limb grasp, belly spot. | Order From EMMA | ||
| C3H.Cg-Tulp3<hhkr>/H | Tulp3<hhkr> | 6 | Homozygotes have spina bifida and oedema, and die at birth. | Order |
| STOCK Steap3<fred>/A pb | Steap3<fred> | 1 | Abnormalities in red blood cell size and shape. | Order From EMMA |
| Redeye | Homozygous mutant mice exhibit a range of eye defects including pale retinas, vascular defects & white structures present in the eye. | Order | ||
| Reg2<tm1Lchr> | Reg2<tm1Lchr> | 6 | none | Order From EMMA |
| STOCK Mitf<Rorp>/H | Mitf<Rorp> | 6 | Dilute coat/ear/tail colour. Heterozygotes have pigment dilution, while homozygotes lack coat pigment, but retain eye(iris) pigment and do not have small eyes. | Order From EMMA |
| B6;129P2-Rgs5<tm1Dge n>/H | Rgs5<tm1Dgen> | 1 | No visible phenotype. | Order From EMMA |
| Ricky | Order | |||
| RKS-XI | No overt phenotype. Believed to be a silent mutation of Pkd111. | Order | ||
| B6NDen;B6N-Rnf7<tm1a (EUCOMM)Wtsi>/H | Rnf7<tm1a(EUCOMM)Wts i> | 9 | Potential EUMODIC data in the Europhenome database. | Order From EMMA |
| C3H;C-Aff1<Rob>/H | Aff1<Rob> | 5 | Robotic and jerky gait. Heterozygotes exhibit small size, ataxia, adult-onset Purkinje cell loss, cataracts, reduced survival, and low fertility. | Order From EMMA |
| sa mu | Muted<mu> | 13 | sa: silky coat with a high sheen, mu/mu have fur of a muted brown colour. | Order |
| Foxq1<sa> | 13 | |||
| SAA2 | None. | Order From EMMA | ||
| C57BL/6Apb-Rc3h1<san >/Apb | Rc3h1<san> | 1 | Autoimmune disease, ANA, lymphadenopathy, splenomegaly, hyper IgG, SLE. | Order From EMMA |
| SB1 | Reduced hearing by clickbox. | Order | ||
| SB2/1 | Reduced hearing | Order From EMMA | ||
| B6;129P2-Scube3<tm1D gen>/H | Scube3 | 17 | No visible phenotype. | Order From EMMA |
| C3H;C-Sbc/H | Sbc | 16 | Identified in circadian rhythm screen. These mice change their period length from normal to long after a light pulse is given at CT16 (circadian time). | Order From EMMA |
| C3H;C-Sfrp2<C50F>/H | Sfrp2<C50F> | 3 | Normal. | Order |
| B6J.Cg-Sfrp2<l153N>/ H | Sfrp2<I153N> | 3 | Order | |
| B6J.Cg-Sfrp2<l153N>/ H | No Overt Phenotype. Full description available from Europhenome | Order | ||
| B6.Cg-Sfrp2<C50F>/H | Sfrp2<C50F> | 3 | Order | |
| B6.Cg-Sfrp5<Q27STOP> /H | Sfrp5<Q27stop> | 19 | Order | |
| Sherbert | Order | |||
| C3H.Cg-Sfl/H | Sfl | 2 | Identified in circadian rhythm screen. Mice carrying this mutation have no phase shifting response to a light pulse given at CT16. | Order From EMMA |
| C3H.Cg-Sci/H | Sci | 8 | Identified in circadian rhythm screen. Short circadian period of wheel-running activity (22.5 hrs rather than 23.5 hrs). Wheel running activity is about 10% of control animals. | Order From EMMA |
| C3H;C-Sic/H | Sic | 7 | Sickly . Classed as harmful. Heterozygotes are small and sickly. Mutation has not been tested for homozygosity. The Sickly mice are marginally smaller than wildtype sibs at birth and dramatically smaller (<50%) at weaning. The nature of this growth defect has yet to be investigated. Heterozygous mice are also prone to infection. | Order From EMMA |
| C3H;C-Jag1<Slalom>/H | Jag1<Slalom> | 2 | These mice exhibit head weaving and shaking behaviour. | Order From EMMA |
| B6;129P2-Slc7a10<tm1 Dgen>/H | Slc7a10<tm1Dgen> | 7 | No visible phenotype. | Order From EMMA |
| Slip | Order | |||
| C3H.Cg-Sgh/H | Sgh | 4 | Mice carrying this mutation demonstrate a low endurance of wheel running activity which is reduced to about 10% of control values. | Order From EMMA |
| SMN E134K Transgenic | None. | Order From EMMA | ||
| SMNDelta5 | None. | Order From EMMA | ||
| SMNDelta5-SMN2Low | Rescues post natal lethality of SMN2 low strain | Order From EMMA | ||
| C3H;C-Spgl/H | Heterozygotes have polydactyly of the hind limbs. Homozygotes have polydactyly of all four limbs. | Order From EMMA | ||
| C3H.Cg-Celsr1<Scy>/H | Celsr1<Scy> | 15 | Mice carrying this mutation exhibit circling behaviour. | Order From EMMA |
| C3H;C-Strg/H | Strg | X | Striped and greasy. | Order |
| Svc (GENA 291) | Col4a1<Svc> | 8 | Small with vacuolar cataract | Order |
| C3H101H-Dync1h1<Swl> /H | Dync1h1<Swl> | 12 | Sprawling, abnormal posture and locomotion from defective position sense mainly affecting hind limbs, myelination deficient, deficiency of sensory receptors, spindles virtually absent from hind limbs. | Order From EMMA |
| sy<a> | Shaker with syndactylism Albany. | Order | ||
| t<h51>t<h18> | t<h18> | 17 | Lethal when homozygous. | Order |
| t<h51> | 17 | |||
| t<lowH> | 17 | |||
| STOCK t<h7> | t<h7> | 17 | Order | |
| Ta<44H> | TA<Fa> like ie heterozygous females-striped, Hemizygous males-weak teeth, no guard hairs, bald tails, very little hair behind ears. | Order From EMMA | ||
| TAS2 | Belly spot, head spot, white feet (variable). | Order From EMMA | ||
| TAS4 | Multiple white spotting over entire body | Order From EMMA | ||
| tde | Grxcr1<pi-tde> | 5 | insertional mutation Tasmanian devil | Order |
| Tesod-36 | Order | |||
| TESOD-37 | Order | |||
| C3H101H-Cacna1a<tg>/ H | Cacna1a<tg> | 8 | Tottering phenotype. Homozygotes have wobbly gait from 3-4 weeks and intermittant seizures. Heterozygotes appear normal. | Order |
| Tg(Leftb-cre)1Hmd | Tg(Leftb-cre)1Hmd | UN | Order | |
| Tg(Sox2-cre)1Amc | Tg(Sox2-cre)1Amc | UN | Order | |
| Tg(T-cre)1Lwd | Tg(T-cre)1Lwd | UN | Order | |
| Tg(Wnt1-cre)11Rth | Tg(Wnt1-cre)11Rth | UN | Order | |
| B6;CB-Tg(PMP22)C22Cl h/H | Tg(PMP22)C22Clh | UN | Shaking & unsteady gait. | Order From EMMA |
| (B6xCB)F2-Tg(PMP22)M Y41Clh | Tg(Pmp22)My41Clh | UN | Shaky & unsteady gait. | Order |
| Tiffany | Mice exhibit eye defects. Sections of the lens diffract light differently. | Order | ||
| TM/45 | Abnormal response to Intraperitoneal Glucose Tolerance Test at 24 weeks of age. | Order From EMMA | ||
| TM/47 | Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. | Order From EMMA | ||
| TM/58 | These mice have an abnormal walking posture, appearing as though the hips are fused. Histological examination shows this to be a muscular phenotype. | Order From EMMA | ||
| TM/59 | Abnormal response to Intraperitoneal Glucose Tolerance Test at 12 weeks of age. Fasting hyperinsulinaemia at 16 weeks. Mice are significantly heavier than wildtype at 12 and 16 weeks of age. | Order From EMMA | ||
| TM/60 | Abnormal response to Intraperitoneal Glucose Tolerance Test at 12 weeks of age. Abnormal IPGTT and fasting hyperinsulinaemia at 16 weeks. Mice are significantly heavier than wildtype at 12 and 16 weeks of age. | Order From EMMA | ||
| TM4 | High T60 in intraperitoneal glucose tolerance tests. | Order From EMMA | ||
| B6;129P2-Tmem67<tm1D gen>/H | Tmem67 | 4 | No visible phenotype | Order From EMMA |
| TMR/10 | Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. | Order From EMMA | ||
| B6;129P2-Tpcn1<tm1Dg en>/H | Tpcn1 | 5 | No visible phenotype. IVF/1772.1k - short tail, IVF/1772.1m- tail kink. | Order From EMMA |
| C3H.Cg-Pmp22<Tr-1H>/ H | Pmp22<Tr-1H> | 11 | Tremors with seizures. Tremors, muscle weakness. | Order From EMMA |
| C3H;C-Pmp22<Tr-2H>/H | Pmp22<Tr-2H> | 11 | Tremors, muscle weakness. | Order From EMMA |
| Trembly | Muscular dystrophy, small size, muscle wasting. | Order | ||
| B6;129P2-Trpc4<tm1Dg en>/H | Trpc4 | 3 | No visible phenotype. | Order From EMMA |
| B6;129P2-Trpc6<tm1Dg en>/H | Trpc6 | 9 | No visible phenotype. | Order From EMMA |
| UMLC-TM/12 | Statistically lowered body weight & plasma levels of glucose after an overnight fast at 12 & 16 wks of age. DEXA at 14 wks: decreased body weight, lean & total tissue, BMD & BMC. | Order | ||
| UMLC-TM/6 | Statistically elevated body weight & plasma levels of glucose, leptin & adiponeptin after an overnight fast at 12 & 16 wks of age. In addition elevated levels of insulin at 16wks of age. DEXA at 14wks: increased fat mass & % fat. | Order | ||
| UTR/mdx (TEX) | This stock contains a tetracyclin inducible utrophin transgene when crossed with MCK-tTA mice. | Order From EMMA | ||
| v<ALB> | Cdh23<v-Alb> | 10 | Waltzer Albany. | Order From EMMA |
| C3H;C-Vng/H | Vng | 5 | Small. One low ear. | Order From EMMA |
| B6.129P2-Vnn1<tm1Pna >/H | Vnn1<tm1Pna> | 10 | Order | |
| B6.129P2-Vnn1<tm1Pna >/H | Vnn1<tm1Pna> | 10 | Order | |
| B6;129P2-Vipr1<tm1Dg en>/H | Vipr1 | 9 | No visible phenotype. | Order From EMMA |
| C3H101H-Vm/H | Heterozygote males have a high probability of being sterile. Visceral myopathy. Off white coat colour, intestinal problems in some animals. Males may be sterile. Older animals develop tremors. Homozygotes die soon after birth with major kidney abnormalities. | Order | ||
| C3H;C-Egfr<Wa5>/H | Egfr<Wa5> | 11 | Small eyes, eyes open at birth, curly whiskers and coat. Heterozygotes have open eyelids and curly whiskers at birth. The first coat has a crimped appearance and subsequent coats are wavy/rough. | Order From EMMA |
| wavy coat | Mice carrying this mutation have a wavy coat. | Order From EMMA | ||
| C3H;C-Whto/H | Whto | 7 | White toes. Heterozygous Whto mice display white belly spots and/or white toes. Homozygotes would appear to be embryonic lethal. | Order From EMMA |
| STOCK Whrn<wi>/H | Whrn<wi> | 4 | Deaf, head tossing and circling. Whirler. | Order From EMMA |
| C3H101H-Wnt3a<vt>/H | Wnt3a<vt> | 11 | Vestigial tail (2) Homozygotes have very short tails, varying form complete absence to about half normal length. | Order |
| C3H101H-Eef1a2<wst>/ H | Eef1a2<wst> | 2 | Wasted homozygotes can be recognised at 20 days of age by tremor and uncoordinated body movements. They develop progressive paralysis and do not survive beyond 30 days. The wasted heterozygotes have normal viability. Also contains Ra. The ragged heterozygotes have thin, ragged coats. The homozygotes are almost naked and are semi-lethal. | Order |
| C57BL/6J-Chr Y<POS>/ H | May show XY sex reversal and hermaphroditism. | Order | ||
| C3H;C-Ankrd11<Yod>/H | Ankrd11<Yod> | 8 | Craniofacial, broad face. Heterozygotes (Ankrd11<Yod>/+) have readily distinguishable craniofacial features. Further to this, abnormal bone morphology including an abnormally small growth plate, negligible chondrocyte hypertrophy and a dramatically reduced zone of woven bone formation have been detected. | Order |
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