| Strain Name | Gene/Allele Symbol | Chr | Phenotype | Availability |
|---|---|---|---|---|
| (beta)-globin (mu)MT <-/-> | (mu)MT<-/-> produces IgM H-chains. | Order | ||
| B6J.129-Kcnj16<tm1Sj tu>/H | Kcnj16 | 11 | Disrupted Kir 5.1 Potassium Channel. Phenotype not known at this point. | Order |
| 101/H | Inbred strain. | Order | ||
| 102/H | Wild type, inbred strain. | Order | ||
| 10Bob | Affected mice head-bob, circle and walk backwards. | Order | ||
| 129S9/SvEvH-Nodal<tm 1Rob>/H | Nodal<tm1Rob> | 10 | Heterozygote viable. Homozygote early developmental lethal (does not gastrulate). | Order |
| 129P2/OlaHsd | The mice have yellow coats and late onset severe vacuolation in brain (700+ days). | Order | ||
| 129P2/OlaHsd-Prnp<tm 2Edin>/H | Prnp<tm2Edin> | 2 | No expression of the Prnp gene. Abnormalities in synaptic transmission, circadian rhythm and sleep. Increased susceptability to oxidative stress and copper toxicity. Cellular phenotypes in T cell activation. | Order From EMMA |
| 129S/SvEvNimrH | Inbred strain. | Order | ||
| 129S9/SvEvH | Wildtype. | Order | ||
| 129/terSv - TgN(Hbb- b) 83Clo/Ws | Tg(Hbb-b1)83Clo | UN | Reiterated transgene is detectable by DNA in situ hybridisation. | Order |
| 129/terSv-TgN(Hbb-b1 )83Clo, Pax6<Sey/+>/Ws | Pax6<Sey> | 2 | Reiterated transgene is detectable by DNA in situ hybridisation. | Order From EMMA |
| Tg(Hbb-b1)83Clo | UN | |||
| 129S9/SvEvH.B6-a/H | a | 2 | Black coat colour. The non-agouti locus from C57BL/6J has been bred to congenicity on a 129S9/SvEvH background. This stock is homozygous for non-agouti (a/a). | Order |
| 129-Fgfr3<tm1.1Aomw> /Aomw | Fgfr3<tm1.1Aomw> | 5 | All homozygous males, some homozygous females and some heterozygous males develop an abnormal skull phenotype sometimes with malocclusion, and may be smaller in size. The phenotype is not fully penetrant. Refer to publication for further information: PMID:19086028. | Order From EMMA |
| A/JH | Inbred strain. | Order | ||
| A.129P2-Nat2<tm1Esim >/H | Nat2<tm1Esim> | 8 | No overt phenotype. | Order From EMMA |
| C3H101H-a<13H>/H | a<13H> | UN | (hair - colour) non-agouti-13-Harwell, umbrous effect. | Order |
| C3H101H-a<16H>a<l>/H | a<16H> | 2 | (coat colour) black back and pinna hairs and agouti belly and flanks. Homozygotes die prenatally. | Order |
| a<l> | 2 | |||
| C3H101H-a<17H>/H | a<17H> | UN | (hair - colour) non-agouti-17-Harwell. | Order |
| C3H101H-a<18H>/H | a<18H> | 2 | Homozygotes are non-agouti with very dark pinna hairs. A/a<18H> looks wild-type. a/a<18H> look umbrous i.e. non-agouti with agouti hairs along side of body and on the belly. | Order From EMMA |
| C3H101H-a<19H>/H | a<19H> | UN | (hair - colour) non-agouti-19-Harwell, black pinna hairs. | Order |
| C3H101H-a<20H>/H | a<20H> | UN | (hair - colour) non-agouti-20-Harwell. | Order |
| C3H101H-a<da>/H | a<da> | 2 | (hair - colour) Non-agouti with dark agouti belly. | Order |
| C3H101H-a<t-2H>/H | a<t-2H> | 2 | (hair - colour) black and tan. | Order |
| C3H101H-a<tl>/H | a<tl> | UN | Resembles a<t> but there is no clear dividing line between black on the back and tan on the belly. Additionally, the tan colour is present on face spreading above the eyes. | Order |
| C3H101H-a<u>/H | a<u> | 2 | (hair - colour) agouti-umbrous. | Order |
| STOCK A<y>/H | A<y> | 2 | (hair - colour, eye - colour, size - obesity, sterile) heterozygotes all the hair pigment is yellow and the eyes are black; they usually become obese and sterile after the first few months. | Order |
| B6.Cg-Tg(ACTFLPe)920 5Dym/H | Tg(ACTFLPe)9205Dym | UN | No overt phenotype. | Order From EMMA |
| C3H101H-Ada<b>/H | Ada<b> | UN | Order | |
| C3H101H-Ada<c>/H | Ada<c> | UN | Order | |
| Ada<a> | UN | |||
| B6;129P2-Adamts1<tm1 Dgen>/H | Adamts1 | 16 | No overt phenotype. | Order From EMMA |
| B6;129P2-Adamts2<tm1 Dgen>/H | Adamts2 | 11 | No overt phenotype. | Order From EMMA |
| B6;129P2-Adcyap1r1<t m1Dgen>/H | Adcyap1r1 | 6 | No visible phenotype. | Order From EMMA |
| 129P2/OlaHsd-Fbxl3<G t(CB0226)Wtsi>/H | Fbxl3 | 14 | Order | |
| C3H.Cg-Fbxl3<Afh>/H | Fbxl3<Afh> | 14 | Identified in circadian rhythm screen. Mutants have a long circadian period 24.23hr (a) and 24.12hr (b). | Order From EMMA |
| Akt2<tm1Wtsi> | Akt2 | 7 | None. | Order |
| Tg(DSPMKP3)Ox(Albert ) | Order | |||
| Ananisi | An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. | Order From EMMA | ||
| Anaya | An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. | Order From EMMA | ||
| Andromeda | An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. | Order From EMMA | ||
| TgN(DSPMKP3)Ox(Angel a) | Order | |||
| Ann Boleyn | Anb | UN | Heterozygotes have polydactyly of the hind limbs. Homozygotes have polydactyly of all four limbs. | Order |
| TgN(DSPMKP3)Ox(Annek a) | Order | |||
| Antonia | An ENU-induced mutation causing heritable anti-nuclear antibodies and variable proliferative and membranous glomerulonephritis with partial dominant phenotype and penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry and immunoglobulin levels. | Order From EMMA | ||
| C57BL/6J-Apc<Min>/5H | Apc<Min> | 18 | Mice develop life-shortening intestinal polyposis. | Order From EMMA |
| C57BL/6J-Apc<Min>/2H | Apc<Min> | 18 | (adenoma - anaemia) multiple intestinal neoplasia. | Order From EMMA |
| ApoE/PAI-1 | Apoe<tm1Bres> | 7 | Shortened life span. | Order From EMMA |
| ApoE/PLGN | Apoe<tm1Bres> | 7 | Rectal prolapse. Shortened life span in homozygotes. | Order From EMMA |
| apoE tPA | Apoe<tm1Bres> | 7 | None. | Order From EMMA |
| Plat<tm1Mlg> | 8 | |||
| apoE tTg | Apoe<tm1Bres> | 7 | None. | Order From EMMA |
| Tgm2<tm1Gml> | 2 | |||
| STOCK Ar<Tfm>/H | Ar<Tfm> | X | Hemizygous males are outwardly female in appearance but internally they have testes. | Order |
| Araf<tm1Mmc> | Araf<tm1Mmc> | X | Araf knockout mice litters are approximately one-third to half the size of their wildtype siblings from day 3 to pre weaning and so do not normally reach breeding age. However, placing them on supplementary diet or removing competition from other siblings, allows some to survive post weaning. Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-raf protein Kinase gene. | Order |
| Araf<tm1Mmc> | Araf<tm1Mmc> | X | X-linked gene. | Order |
| Araf:Beta-geo | Order | |||
| Araf<tm1Mmc> | Araf<tm1Mmc> | X | Araf knockout mice litters are approximately one-third to half the size of their wildtype siblings from day 3 to pre weaning and so do not normally reach breeding age. However, placing them on supplementary diet or removing competition from other siblings, allows some to survive post weaning. Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-raf protein Kinase gene. | Order |
| B6;129S4-Rhog<tm1Tnr >/H | Rhog<tm1Tnr> | 7 | Mild hyper reactivity of lymphocytes to antigen receptor engagement. | Order From EMMA |
| Ariel | Hind limb paralysis from day 12 in homozygotes. | Order | ||
| C3H101H-Atp7a<Mo-10H >/H | Atp7a<Mo-10H> | X | (hair - colour) mottled. | Order |
| C3H101H-Atp7a<Mo-11H >/H | Atp7a<Mo-11H> | X | (hair - colour) mottled. | Order |
| C3H101H-Atp7a<Mo-12H >/H | Atp7a<Mo-12H> | X | (hair - colour) mottled. | Order |
| C3H101H-Atp7a<Mo-13H >/H | Atp7a<Mo-13H> | X | (hair - colour) mottled. | Order |
| C3H101H-Atp7a<Mo-14H >/H | Atp7a<Mo-14H> | X | (hair - colour) mottled. Males do not survive. | Order |
| C3H101H-Atp7a<Mo-17H >/H | Atp7a<Mo-17H> | X | (hair - colour) mottled. | Order |
| Atp7a<Mo-18H> | Atp7a<Mo-18H> | UN | Mottled coat. Hemizygous males die in utero. The coat colour of females are typical Atp7a<Mo> but Atp7a<Mo-18H> has not been studied in depth. | Order |
| C3H101H-Atp7a<Mo-blo >/H | Atp7a<Mo-blo> | X | (hair colour) blotchy. | Order |
| C3H101H-Atp7a<Mo-ca> /H | Atp7a<Mo-ca> | X | (hair colour) Mottled candy. | Order |
| C3H101H-Atp7a<Mo-dp> /H | Atp7a<Mo-dp> | X | (hair - colour, gait, skeleton) mottled dappled. | Order |
| C3H101H-Atp7a<Mo-spt >/H | Atp7a<Mo-spot> | X | (hair - colour) mottled spot. | Order |
| C3H101H-Atp7a<Mo-to> /H | Atp7a<Mo-to> | X | (hair - colour) mottled tortoiseshell. | Order |
| C3H101H-Atp7a<Mo-vbr >/H | Atp7a<Mo-vbr> | X | (hair - colour, viable brindled. | Order |
| C3H;C-Pde6b<atrd1>/H | Pde6b<atrd1> | 5 | Eyes-slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<atrd2>/H | Pde6b<atrd2> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<atrd3>/H | Pde6b<atrd3> | 5 | Eyes- slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<rd1-2H>/ H | Pde6b<rd1-2H> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<rd1-3H>/ H | Pde6b<rd1-3H> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| C3H;C-Pde6b<rd1-4H>/ H | Pde6b<rd1-4H> | 5 | Slow onset retinal degeneration. | Order From EMMA |
| B(Beta)DB<tm2Ked> | Dtnb | 12 | None observed. | Order |
| B10.L-Lsh | Slc11a1<r> | 1 | Order | |
| B10ScSn.BXSB-(D1Mit3 -D1Mit320) Chr Y<BXSB/MpJ>/BjmjrH | Enhanced autoantibody spectrum and titre. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit3 -D1Mit235) Chr Y<BXSB/MpJ>/BjmjrH | Enhanced autoantibody spectrum and titre. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit1 23-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH | Enhanced autoantibody spectrum and titre. Glomerulonephritis susceptibility. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit2 35-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH | Glomerulonephritis susceptibility. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit3 03-D1Mit305) Chr Y<BXSB/MpJ>/BjmjrH | Glomerulonephritis susceptibility. | Order From EMMA | ||
| B10ScSn.BXSB-(D1Mit3 3-D1Mit223) Chr Y<BXSB/MpJ>/BjmjrH | ANA, 75% mortality, enhanced autoantibody titre, severe glomerulonephritis. | Order From EMMA | ||
| B6J.CBA-TgN(HDexon1) 61Gpb | Tg(HDexon1)61Gpb | UN | Huntington's disease, tremors, weight loss, movement disorders, died on average at 7 months old. | Order |
| B6.129-Igf1r<tm1.2Mh z>/Orl | Igf1r<tm1.2Mhz> | 7 | Live longer; resistant to oxidative stress. | Order |
| B6.Cg-Mir155<tm1.1Br d>Tyr<c-Brd>/H | Mir155<tm1.1Brd> | 16 | No visible phenotype is associated with this mutation but the mice do exhibit reduced lung airway remodelling & deficient B-cell, T-cell & dendritic cell function. This mutation is on a C57BL/6<c-/c-> background and is albino in appearance. The BIC mice (EMMA ID EM:02231) have been backcrossed at least 5 times to C57BL/6, thus making them suitable for bone marrow transplantation, without rejection, to any C57BL/6 mice, regardless of coat color. | Order From EMMA |
| Tyr<c-Brd> | 7 | |||
| B6;D2-Tg(Sycp1-cre)4 Min/J | Tg(Sycp1-cre)4Min | UN | None given. | Order |
| B6CBA-Tg(HDexon1)61G pb | Tg(HDexon1)61Gpb | UN | Model for Huntington's disease, tremors, weight loss, movement disorders, die on average at 7 months old. | Order |
| BAC3 | Normal. | Order | ||
| BALB/c | Albino. | Order | ||
| BALB/cOla | White coat colour. | Order | ||
| C.Cg-Il1rn<tm1Nick>/ Nick | Il1rn<tm1Nick> | 2 | Strain sporadically and independently develops rheumatoid-like arthritis, localised psoriasis-like lesions and patchy transmural destructive arteritis of the elastic vessels. Hygiene dependent (negative correlation). Different strain dependence of each disease. This strain, our SPF lab, 80% affected (each disease independently) at 200 days. | Order From EMMA |
| CBy.129-Rag2<tm1Fwa> /H | Rag2<tm1Fwa> | 2 | Chronic intestinal inflammation, colitis. | Order From EMMA |
| CBy.129-Cd44<tm1Ugu> Rag2<tm1Fwa>/H | Cd44<tm1Ugu> | 2 | Chronic intestinal inflammation, colitis. | Order From EMMA |
| Rag2<tm1Fwa> | 2 | |||
| CBy.129-Cd44<tm2.1Ug u> Rag2<tm1Fwa>/H | Rag2<tm1Fwa> | 2 | Mice are homozygous for both Rag-/- and CD44v10-/- knockouts. Rag2-/-, no mature T and B cells. CD44v10-/-, strongly reduced symptoms in autoimmune diseases. Used in mouse models of experimental colitis. | Order From EMMA |
| Cd44 | 2 | |||
| CBy.129-Cd44<tm1.1Ug u> Rag2<tm1Fwa>/H | Cd44<tm1.1Ugu> | 2 | Rag2-/-: no mature T and B cells. CD44v6v7-/-: strongly reduced symptoms in autoimmune diseases. | Order From EMMA |
| Rag2<tm1Fwa> | 2 | |||
| BALB/cPye | Order | |||
| C3H101H A/A<w>-Bbn/H | Bbn | UN | Affected animals are deaf and exhibit headbobbing and circling behaviour. | Order From EMMA |
| C3H101H-Bhd/H | Bhd | X | (head - nose) broad-headed. | Order |
| BHV11 | Abnormal craniofacial features. | Order From EMMA | ||
| BHV26 | The alternation score suggest this line has a potential short term working memory deficit. | Order From EMMA | ||
| BHV31 | High anxiety. | Order From EMMA | ||
| BHV32 | Hyperactivity. | Order From EMMA | ||
| BHV43 | Possible short-term working memory deficit indicated by reduced spontaneous alternation in the Y-maze. | Order From EMMA | ||
| BHV48 | Rgs18 | 1 | None apparent, in heterozygotes. | Order From EMMA |
| C3H.Cg-Trpc3<Mwk>/H | Trpc3<Mwk> | 3 | Staggering, ataxic with limited movement in back legs. Heterozygotes are usually small. | Order From EMMA |
| ABL | Inbred strain. | Order | ||
| C3H101H-Fras1<bl>/H | Fras1<bl> | 5 | (eye, feet, kidney, skin) blebbed. | Order From EMMA |
| C57BL/6J-blst/H | blst | UN | Spontaneous recessesive coat colour mutation - light grey coat colour. | Order From EMMA |
| C57BL/6J-Btnt/H | Btnt | UN | Tan coat colour on belly. | Order From EMMA |
| C3H;C-Snap25<Bdr>/H | Snap25<Bdr> | 2 | Poor sight. Blind drunk. Small at weaning. SHIRPA anomalies including reduced or absent visual placing and staggering gait. Homozygotes have not been identified. | Order From EMMA |
| C57BL/6J-Blite/H | Blite | UN | White with non-agouti patches. Some patches reverting to non-agouti are visible in a small number of offspring. Timed matings of heterozygous stock can yield oedematous embryos. | Order From EMMA |
| BLUFF | Fluffy coat, abnormal hair distribution and texture. | Order | ||
| C3H101H-Papss2<bm>/H | Papss2<bm> | 19 | (skeleton) dwarfism - cleft palate brachymorphic. | Order |
| BMD2 | Low bone mineral density. | Order | ||
| Bmp5<se-19H> | Bmp5<se-19H> | UN | Short-ear. | Order |
| Bmp5<se-20H> | Bmp5<se-20H> | UN | Short-ear. | Order |
| Bmp6<tm1Rob> | Bmp6<tm1Rob> | 13 | Mice show no overt phenotype. | Order From EMMA |
| Bmp7<tm2Rob> | Bmp7<tm2Rob> | 2 | Homozygous embryonic lethal. | Order From EMMA |
| Bmp7<tm1Rob> | Bmp7<tm1Rob> | 2 | This strain is a null allele of BMP7 generated by replacing the BMP7 coding sequence by a neomycin cassette. BMP7 is required in the metanephric mesenchyme of the developing kidney to support maintenance of this cell population during organogenesis. Homozygous lethal at birth due to kidney agenesis. | Order From EMMA |
| Zic3<Bn>, Atp7a<Mo-b r> | Zic3<Bn> | X | (coat colour) mottled brindled, Bent tail. | Order |
| C3H101H-Nsdhl<Bpa-1H > | Nsdhl<Bpa-1H> | X | (skin, size, tail ) bare patches. | Order |
| C3H101H-Nsdhl<Bpa-3H > | Nsdhl<Bpa-3H> | X | (skin - skeleton) scarring on females at 4 days old. More females than males born and some have spine abnormalities. Bare patches are clearly visible at weaning. | Order |
| C3H101H-Nsdhl<Bpa-4H > | Nsdhl<Bpa-4H> | X | (skin - skeleton) phenotype classed at 8 days but are barely visible at weaning. More females than males are born and they are prone to spinal abnormalities. | Order |
| C3H101H-Nsdhl<Bpa-5H > | Nsdhl<Bpa-5H> | X | (skin - skeleton - size) phenotype classed at 8 days some are small at birth. More females than males born and they are prone to spinal abnormalities. | Order |
| C3H101H-Nsdhl<Bpa-6H > | Nsdhl<Bpa-6H> | X | (skin) bare patches classed at 4 days and are clearly visible at weaning. | Order |
| C3H101H-Nsdhl<Bpa8H> /H | Nsdhl<Bpa-8H> | X | Male lethal. Females are classified at 8 days by scarring on the skin, small at weaning. The adult females are striped. | Order From EMMA |
| C3H101H-Br/H | Br | 17 | (nose - mouth, kidneys - size) brachyrrine. | Order |
| Brd7<tm1aWtsi> | Brd7 | 8 | None. | Order From EMMA |
| Brn3a Knockout | Pou4f1 | 14 | Homozygote neonate lethality caused by lack of suckling due to defects in sensory and motor neurons. | Order |
| Brn3b Knockout | Pou4f2 | 8 | Homozygotes are blind due to failure of the retinal ganglia to develop. | Order |
| B6NDen;B6N-Brpf1<tm1 a(EUCOMM)Wtsi>/H | Brpf1<tm1a(EUCOMM)Wt si> | 6 | Order From EMMA | |
| C3H101H-Gsdma3<Bsk>/ H | Gsdma3<Bsk> | 11 | (skin, eyes) bareskin, corneal opacities. | Order |
| Bstk | (hair - colour) Affected individuals have a belly spot and light feet. | Order | ||
| bv | bv | 5 | Bronx Waltzer. Recessive mutant; hyperactivity, circling, headbobbing and deafness in the homozygote. | Order From EMMA |
| bv (Bronx Waltzer) | bv | 5 | Bronx Waltzer. | Order From EMMA |
| C.D2-vil6 | Order | |||
| C3H-nr/H | nr | 8 | Homozygotes are smaller in size and have hyperactive ataxic behaviour. | Order |
| C3H/HeH | Order | |||
| C3H;C-Chd7<Todo>/H | Chd7<Todo> | 4 | Headweaving and circling in heterozygotes. Homozygotes die at mid gestation with vascular and brain defects. | Order From EMMA |
| C3H;C-Chd7<Edy>/H | Chd7<Edy> | 4 | Headweaving/circling. | Order From EMMA |
| C3H;C-Chd7<Dz>/H | Chd7<Dz> | 4 | Dizzy. Heterozygote animals are small at birth with slight kink in tail and exhibit head weaving and circling behaviour. | Order From EMMA |
| B6.Cg-Il1rn<tm1Nick> /Nick | Il1rn<tm1Nick> | 2 | Strain resistant to arthritis, arteritis and psoriasis (seen in BALB/c) but highly susceptible to undefined 'malaise' under conventional conditions. | Order From EMMA |
| B6.129P2-Fgfr3<tm1.1 Aomw>/Aomw | Fgfr3<tm1.1Aomw> | 5 | All homozygous males, some homozygous females and some heterozygous males develop an abnormal skull phenotype sometimes with malocclusion, and may be smaller in size. The phenotype is not fully penetrant. | Order From EMMA |
| C57BL/6-Lep<ob>/H | Lep<ob> | 6 | Order | |
| B6CBF1-Tg(ATXN3*)84. 2Cce/H | Tg(ATXN3*)84.2Cce | UN | Slowly progressive cerebellar defecit from 4weeks of age; wide flattened gait, clasping of all 4 limbs, neuronal loss, gliosis & neuronal intranuclear inclusions present in the pons & cerebellum, peripheral nerve demyelination. | Order From EMMA |
| C57BL/6Apb-Ptprc<loc >/Apb | Ptprc<loc> | 1 | Decreased expression of CD45 on CD19+ B cells etc. | Order From EMMA |
| C57BL/6Apb-Zap70<mur >/Apb | Zap70<mur> | 1 | Reduced naïve CD4+ and CD8+ T cells which are hyperactivated, reduced CD4+ cells, defect in TCR signal transduction, impaired but not severe response to anti-TCR stimulation, T cell intrinsic defect, elevated serum levels of IgG2b. | Order From EMMA |
| C57BL/6J-A<vy>/H | A<vy> | 2 | Order | |
| C57BL/6J-Krt25<Re>/H | Krt25<Re> | 11 | Order | |
| C57BL/6J-Kitl<Sl-d>/ H | Kitl<Sl-d> | 10 | Order | |
| C57BL/6J-Ucp1<m1H>/H | Ucp1<m1H> | 8 | Homozygotes are unable to thermoregulate. | Order |
| STOCK a<t>/H | a<t> | 2 | (hair - colour) the back is black and the belly cream or yellow. | Order |
| C57BL/Ola-Gpi1-s<c>, c/Ws | Gpi1<c> | 7 | Order From EMMA | |
| B6.AK-Gpi1<a>/Ws | Gpi1<a> | 7 | Order From EMMA | |
| C57bl/ws-TgN(Hbb-b1) 83Clo/ws | Tg(Hbb-b1)83Clo | UN | None expressed. | Order From EMMA |
| C57BR/cd | Hepatomas in 25% of males. | Order | ||
| C3H101H-Krt71<Ca-2H> /H | Ca<2H> | UN | (Coat - texture) caracul. Homozygotes are indistinguishable from heterozygotes. Both are fully fertile and viable. Vibrissae are curved, and hair is wavy from time of first appearance until about 4 weeks of age. After this time the waves disappear, but the hair has a plush-like look. | Order |
| Krt71<Ca-d>, Scn8a<m ed> | Scn8a<med> | 15 | (Coat - texture, motor end plate). | Order |
| Krt71<Ca-d> | 15 | |||
| 129P2/OlaHsd-Tpcn1<G t(XG716)Byg>/H | Tpcn1 | 5 | Order | |
| B6;129-Capn5<tm1Nde> /H | Capn5<tm1Nde> | 7 | None apparent. | Order From EMMA |
| TgN(UbiCFL)Ox(Calvin ) | Order | |||
| Candy | Hyperglycaemia, glycosuria. Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| Candy2 | Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| Candy3 | Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| Candy4 | Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| Candy5 | Elevated plasma glucose and phosphate at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. | Order From EMMA | ||
| B6;129P2-Capn1<tm1Dg en>/H | Capn1 | 19 | No overt phenotype | Order From EMMA |
| C3H.C-Casp3<I216F>/H | Casp3 | 8 | Reduced apoptosis in homozygotes. Phenocopies Caspase 3 null alleles. | Order From EMMA |
| C3H-Cat2/H | Cat2 | 1 | (eye - cataract) cataract-2 dominant cataract. | Order |
| C3H101H-Cryga<tol>/H | Cryga<tol> | 1 | Dominant cataract. | Order |
| C3H-Cat5<To2>/H | Cat5<To2> | 10 | (eye - cataract) cataract-5 dominant cataract. | Order |
| CBA-TgN(IL5) 1 GlX | Transgenic pups have high leucocyte counts and are readily identifiable by differential leucocyte counts. | Order From EMMA | ||
| CBA/CaH | Xic<a> | X | Order | |
| Runx1t1<tm1Fc> | Runx1t1<tm1Fc> | 4 | Order | |
| CCBAN3-2371 | Order | |||
| CCBAN4-2513 | Order | |||
| CCBAN4-2547 | Order | |||
| B6;129P2-Ccr9<tm1Dge n>/H | Ccr9 | 9 | None. | Order From EMMA |
| CD2/NPM-ALK | Mice develop tumours of haemopoietic organs within 2 years of age in approx. 10% of mice. | Order From EMMA | ||
| CD45R03 | Under investigation: not severely immunocompromised. | Order | ||
| CD45RABC3 | Under investigation, not severely immunocompromised; no obvious immunological dysfunction. | Order | ||
| CD45RB2 | Under investigation: not severely immunocompromised. | Order | ||
| CD45RO-C817S | Severe defects in B and T cell differentiation and function. | Order | ||
| CD45RO9 | Under investigation, not severely immunocompromised. | Order | ||
| CEMO_S2 | Order | |||
| CEMO_S3 | Order | |||
| CEMO_S5 | Order | |||
| CHANGELING | Motor co-ordination problems & death before weaning age. | Order | ||
| TgN(UbiCFL)Ox(Chelse a) | Order | |||
| Chm | Tyr<c-ch> | 7 | Order | |
| STOCK Oca2<p>Tyr<c-c h>Myo7a<sh1>Prss8<fr>/H | Oca2<p> | 7 | Order | |
| Prss8<fr> | 7 | |||
| Tyr<c-ch> | 7 | |||
| Myo7a<sh1> | 7 | |||
| C3H101H-Flt4<Chy>/H | Flt4<Chy> | 11 | Milky abdomen shortly after birth. (abdomen, feet) chylous ascites. | Order From EMMA |
| Chy-Ma like | (abdomen, feet) chylous ascites. Milky abdomen. Small at birth and weaning. May have low fertility. Some may have coat dilution or headbobbing. | Order | ||
| C3H101H-Chy2/H | (abdomen, feet , tail). Typical chylous phenotype of puffy feet, swollen tail. No knowledge of fate of homozygote. | Order | ||
| Chy5 | Chy5<Ma1> | UN | milky abdomen. | Order |
| Chy6 | Chy6<Ma2> | UN | milky abdomen. | Order |
| C3H101H-Chy7/H | (abdomen, feet) chylous ascites. Milky abdomen. | Order | ||
| CIRCA12 | Identified in circadian rhythm screen. Has a reduced period lengthening response when subjected to constant light conditions. | Order | ||
| CIRCA2 | Long activity under constant dark period. | Order | ||
| CIRCAD21 | Order | |||
| B6.Cg-Cited2<L247P>/ H | Cited2 | 10 | Although the amino acid change occurs in a highly conserved residue. The mutant is homozygous viable and fertile, with no detectable phenotype. In trans to the Knock-out allele, it is viable and phenotypically normal. | Order From EMMA |
| B6J.129-Cited2<tm2Bh a>/H | Cited2<tm2Bha> | 10 | Cre-mediated recombination throughout the entire epiblast of early embryos recapitulates the complete loss of function phenotype of Cited2, which include cardiac malformations, adrenal agenesis, fusion of cranial ganglia, abnormal cardiac neural crest migration, excencephaly and left right patterning defects. | Order From EMMA |
| TgN(UbiCFL)Ox(Cleo) | Order | |||
| CMV Gal4 | None. | Order | ||
| STOCK Tg(Col2a1-cre) 1Bhr/H | Tg(Col2a1-cre)1Bhr | UN | No overt phenotype. | Order From EMMA |
| C3H101H-Col4a1<Bru>/ H | Col4a1<Bru> | 8 | (eyes - cataract - size, skin - colour) bruised. | Order From EMMA |
| STOCK Col4a1<Raw>/H | Col4a1<Raw> | 8 | Retinal ateriolar wiring. Shiny retinal blood vessels. | Order From EMMA |
| STOCK Col4a1<Svc>/H | Col4a1<Svc> | 8 | Small with vacuolar cataract. Also other eye abnormalities. Mutants are small and bruised at birth and tend to remain small throughout life. Variable eye findings, the most consistent of which is a vacuolar cataract. Other eye findings include enlarged eyes, corneal opacity, iris-corneal adhesions, iris-lens adhesions, retinal vascular abnormalities. | Order From EMMA |
| CON | Kitl<Sl-con> | 10 | (coat - colour) steel. Darkly pigmented genitalia and slightly lighter coat in heterozygote. Homozygotes are grey with dark genitalia. | Order |
| Edar<dl> | 10 | |||
| Connexin26-Knockout (C3H) | Gjb2 | 14 | Heterozygotes appear wildtype and can hear, homozygous embryonic lethal. | Order |
| C3H;C-Gjb2<E119stop> /H | Gjb2<E119stop> | 14 | Homozygous lethal, heterozygotes appear as wildtypes. | Order |
| Connexin26<Har1> Wil d type | Homozygous lethal, heterozygotes appear as wildtypes. | Order | ||
| TgN(UbiCFL)Ox(Conrad ) | Order | |||
| Cookson Mouse | Eng | 2 | Order | |
| Cordon Bleu | Cobl | 11 | None. | Order |
| STOCK Scrib<Crc>/H | Scrib<Crc> | 15 | Neural tube defects. | Order |
| C3H.Cg-Scrib<Crc>/H | Scrib<Crc> | 15 | Order | |
| C3H101H-Crm/H | Crm | X | (coat - colour) cream. | Order |
| Cry1<tm1Jhjh> | Cry1<tm1Jhjh> | 10 | Order | |
| 129-Ctsg<tm1.1Roes>/ H | Ctsg<tm1.1Roes> | 14 | Mice deficient in Ctsg are susceptible to fungal infections, despite normal neutrophil development and recruitment. | Order From EMMA |
| CVBA 3'/Utrophin+/-/ mdx | CVBA 3'/Utrophin+/-/mdx mice are transgenic for the dystrophin cDNA with a deletion of exons 17-48 under the control of the MCK promoter. | Order From EMMA | ||
| C3H;C-Gjb2<I128V>/H | Gjb2<I128V> | 14 | Heterozygotes appear wildtype and show normal hearing. | Order From EMMA |
| C3H;C-Chd7<Cycn>/H | Chd7<Cycn> | 4 | Headbobbing/circling. Heterozygotes exhibit headweaving and circling behaviour. Homozygous foetuses exhibit midgestational lethality potentially due to vascular and/or anterior neural tube defects. | Order From EMMA |
| D1ApA63(Knockin) | Order | |||
| C3H;C-Dfp2/H | Dfp2 | 4 | Heterozygotes have dark pigmentation on footpads and additional areas such as tail, ears etc. | Order From EMMA |
| DBA/2 | Non-agouti brown, pink eyes. Susceptible to audiogenic seizures. Spontaneous calcified heart lesions progress with age. | Order | ||
| C3H101H-Dbf/H | Dbf | 1 | Many extra toes on all feet. Homozygote lethal. Dominant, digits - number, limbs - bones, size - small, reduced viability, skull, sterility, cerebrospinal fluid?? | Order From EMMA |
| C3H101H-Dct<slt>/H | Dct<slt> | 14 | Slatey. | Order |
| DDK | Order | |||
| C3H101H-Del(1)55H | (size - birth - weaning) small at birth and weaning. | Order | ||
| C3H101H-Del(1)57H | (size - birth, anaemia) Small at birth and seemingly anaemic. | Order | ||
| C3H101H-Del(1)58H | (size - birth - weaning, hair - colour) small at birth and at weaning with dark coats. | Order | ||
| C3H101H-Del(1)66H | (size - birth - weaning, hair - colour) heterozygote milky abdomen at birth, small at weaning. | Order | ||
| C3H101H-Del(1)70H | (size - birth - weaning, head) small at birth and weaning sometimes with a domed head. | Order | ||
| C3H101H-Del(1)6H | (size - birth - weaning, head) small at birth and weaning, with domed head. | Order | ||
| C3H101H-Del(1)42H | (size - birth - weaning - eyes) small at birth with eyes open and small at weaning with small eyes. | Order | ||
| C3H101H-Del(1)33H | (size - birth - weaning, head) small at birth and weaning, with a slightly domed head. | Order | ||
| C3H101H-Del(1)27H/H | (size - birth weaning, hair - colour) small at birth and weaning, some have white feet. No information available about homozygotes. | Order | ||
| C3H101H-Del(10)69H | (size - birth - weaning, head) heterozygotes small at birth and weaning, with domed head. | Order | ||
| Del(10)Mgf<Sl-28H>41 H | Kitl<Sl-28H> | UN | steel. | Order |
| C3H101H-Del(12)75H | (size - birth weaning, hair - colour, behaviour) small at birth and small at weaning with head bobbing and dark coat. | Order | ||
| C3H101H-Del(13)52H | (size - birth - weaning, hair - colour) small at birth and weaning, sometimes with dark coats. | Order | ||
| C3H101H-Del(13)80H | Del(13)80H carriers are small, with small eyes and domed heads. Del(13)80H +/+ sa has the satin phenotype. | Order From EMMA | ||
| C3H101H-Del(13)36H | Order | |||
| Del(14)Ednrb<s-163H> 10H | Ednrb<s-163H> | UN | Order | |
| Del(14)Ednrb<s-163H> 10H | UN | |||
| Del(14)Ednrb<s-174H> 15H | Ednrb<s-174H> | UN | Order | |
| DelEdnrb<s-174H>15H | UN | |||
| Del(14)Ednrb<s-175H> 14H | Ednrb<s-175H> | UN | Order | |
| DelEdnrb<s-175H>14H | UN | |||
| Del(14)Ednrb<s-175H> 14H | UN | |||
| Del(14)Ednrb<s-179H> 23H | DelEdnrb<s-179H>23H | UN | Order | |
| Ednrb<s-179H> | UN | |||
| Del(14)Ednrb<s-180H> 28H | DelEdnrb<s-180H>28H | UN | Small at birth and weaning. | Order |
| Ednrb<s-180H> | UN | |||
| Del(14)Ednrb<s-181H> 31H | DelEdnrb<s-181H>31H | UN | Order | |
| Ednrb<s-181H> | UN | |||
| Del(14)Ednrb<s-182H> 32H | Ednrb<s-182H> | UN | Order | |
| DelEdnrb<s-182H>32H | UN | |||
| Del(14)Ednrb<s-184H> 29H | Dct<slt> | UN | Order | |
| DelEdnrb<s-184H>29H | UN | |||
| Ednrb<s-184H> | UN | |||
| Del(14)Ednrb<s-187H> 39H | DelEdnrb<s-187H>39H | UN | (size) small with high expression. | Order |
| Ednrb<s-187H> | UN | |||
| Del(14)Ednrb<s-198H> 60H | DelEdnrb<s-198H>60H | UN | Order | |
| Ednrb<s-198H> | UN | |||
| C3H101H-Del(16)51H | (size - birth - weaning, hair - colour) small at birth and weaning, some white feet. | Order | ||
| C3H101H-Del(18)20H | (size - weaining, hair - colour, tail, cleft palate) small at weaning, sometimes white feet, variable tail abnormalities, tail kinks to tight curling of tail, some cleft palates/lips seen in heterozygotes also exencephaly. | Order | ||
| C3H101H-Del(2)59H | (size - birth - weaning, genetalia - colour, head) small at birth and small at weaning with small eyes and domed/short heads and some have dark genitalia. | Order | ||
| Del(2)Sey<2H>82H | Pax6<Sey-2H> | 2 | Small at birth and weaning. Small or closed eyes, white feet. | Order |
| C3H101H-Del(2)Sey<4H >83H/H | Pax6<Sey-4H> | UN | Small eyes and sometimes small at birth. | Order |
| Del(2)Sey<4H>83H | UN | |||
| C3H101H-Del(2)35H | (size - birth - weaning, hair - colour) small at birth and weaning, sometimes white feet, occasional belly spot. | Order | ||
| STOCK Del(3)48H | Small. | Order | ||
| C3H101H-Del(3)64H | (size - birth - weaning, head) small at birth and weaning, unusual shaped heads. | Order | ||
| C3H101H-Del(4)17H | (size - birth - weaning, behaviour - waltzing, skin - colour) small at birth and weaning, waltzer type behaviour, variable white feet. | Order | ||
| C3H101H-Del(5)68H | (size - birth weaning, behaviour) small at birth and weaning with erratic behaviour. | Order | ||
| Del(5)Kit<W-34H>43H | Kit<W-34H> | UN | Order | |
| DelKit<W-34H>43H | UN | |||
| Del(5)Kit<W-35H>47H | DelKit<W-35H>47H | UN | Order | |
| Kit<W-35H> | UN | |||
| Del(5)Ph<2H>25H | Ph<2H> | UN | patch. | Order |
| C3H101H-Del(6)26H | (size - birth weaning, hair - colour) small at birth and weaning with dark (umbrous) coat. | Order | ||
| C3H101H-Del(7)49H | (size - birth - weaning, hair - colour) small at birth and weaning, dark coats, white toes. Phenotype and deletion may not be associated. | Order | ||
| C3H101H-Del(7)56H | (size - birth - weaning, hair - colour) small at weaning, some have milky abdomens. | Order | ||
| C3H101H-Del(8)50H | (size - birth - weaning, hair - colour) small at birth and weaning, with dark coats. | Order | ||
| C3H101H-Del(8)62H | (size, head, behaviour - circling) small, some with short heads, circling. | Order | ||
| C3H101H-Del(8)72H | (size - birth weaning, hair - colour, behaviour) small at birth and weaning, also dark coats. Some show circling behaviour. | Order | ||
| C3H101H-Del(8)7H | (abdomen, feet) chylous ascites. | Order | ||
| C3H101H-Del(8)74H | (feet, tail) milky abdomen, puffy feet and thick tail. | Order | ||
| C3H101H-Del(9)4H | (size - small, white spotting) low grade white head/feet tail spotting, carriers small from birth. | Order | ||
| 129P2/OlaHsd-Tpcn2<G t(YHD437)Byg>/H | Tpcn2<Gt(YHD437)Byg> | 7 | Order | |
| C57BL/6J-H19<tm2Wrk> | H19<tm2Wrk> | 7 | Deletion of the H19 transcription start site shows no effect on imprinting expression or DNA methylation. | Order From EMMA |
| C3H101H-Dh/H | Dh | 1 | dominant hemimelia, Classified at birth by absence of spleen. Toes not always abnormal. Het.show preaxial polydactyly or oligodactyly of the hind limbs, tibial hemimelia, & sometimes reduction of the femur & pubic element of the pelvic girdle, no. etc... | Order |
| C3H;C-Dilp3/H | Dilp3 | UN | Dilated pupils. | Order From EMMA |
| C3H;C-Dilp4/H | Dilp4 | UN | Mice carrying this mutation have permanently dilated pupils. | Order From EMMA |
| C3H101H-Dkf/H | (feet - colour, tail - colour, size - weaning) Darkfoot, dominant, homozygous lethal. Heterozygotes have dark foot-pads and tails, also slightly small at weaning. | Order | ||
| Dl<Slk2H> | Edar<Dl-Slk2H> | UN | Greasy coat, hairy tail. | Order |
| C3H101H-Edar<Dl-slk> /H | Edar<Dl-slk> | 10 | (hair, teeth) sleek. | Order |
| STOCK Tmc1<dn> | Tmc1<dn> | 19 | Deafness. | Order From EMMA |
| C3H101H-Dp(1)6H | Small at birth and weaning. | Order | ||
| C3H101H-Dp(12)7H | joined toes on hind feet. | Order | ||
| C3H101H-Dp(12)9H | dark coat and skin seen on ears, feet and tail with occasional domed head. | Order | ||
| C3H101H-Dp(13)17H | Small at birth and weaning. | Order | ||
| C3H101H-Dp(14)18H | small at birth and weaning, some have dark coats. | Order | ||
| C3H101H-Dp(14)2H | dark coat, small, white toes/feet. | Order | ||
| C3H101H-Dp(15)5H | Slightly small at weaning, some show erratic waltzing type behaviour, variable white feet/tail, dark coats. | Order | ||
| C3H101H-Dp(16)15H | Small at birth and weaning, sticky eyes, domed head. | Order | ||
| C3H101H-Dp(16)8H | Order | |||
| C3H101H-Dp(18)4H | Small with dark coats. | Order | ||
| C3H101H-Dp(2)11H | (size - birth - weaning, hair - colour, behaviour) small at birth and small at weaning with dark coat and showing abnormal behavior. i.e. shaking, head bobbing and very active. | Order | ||
| C3H101H-Dp(3)10H | (size, head) heterozygotes are usually small with a domed head. | Order | ||
| C3H101H-Dp(4)20H | Small at weaning with a short domed head. Homozygous lethality. some dark coat and low grade white spotting on the feet only was seen. | Order | ||
| C3H101H-Dp(7)1H | Small at weaning, dark coats (some). | Order | ||
| C3H101H-Dp(7)16H | small at birth and small at weaning with dark coats. | Order | ||
| C3H101H-Dp(7)19H | Small at birth and weaning. | Order | ||
| C3H101H-Dp(9)12H | Small with dark coat. | Order | ||
| C3H101H-Dp(9)14H | Small at birth and weaning, some have dark coats, short heads and twisted jaws. | Order | ||
| C3H101H-Dp(9)3H | Heterozygotes small at birth and weaning, some fused toes, pointed faces. | Order | ||
| STOCK Lmx1a<dr-J> | Lmx1a<dr-J> | 1 | Deafness, circling behaviour and hyperactivity in homozygotes. They have neuronal migration disorders in the cerebral cortex, cerebellum and hippocampus. White belly spots, short tails and abnormalities of the fallopian tubes (dr<2J> only)are seen in some. | Order |
| C3H101H-Mc1r<E-tob>/ H | Mc1r<E-tob> | 8 | Order | |
| ecd | Cartilage type defect. | Order | ||
| Ednrb<s-136H> | Ednrb<s-136H> | UN | Less spotting than Ednrb<s>. | Order |
| C3H101H-Ednrb<s-162H >/H | Ednrb<162H> | UN | Order | |
| C57BL-Eh/H | Eh | 15 | Hairy ears (Eh). Reduced pinna with tufts of hair on inner surface. Homozygous lethal. Breeding poor when crossed to C57BL/6J. | Order |
| ELK6K<-/->(lambda)<- /-> | Production of rat kappa light chains on mouse lambda and kappa light chain knockout background.(or on mouse kappa-type light chain knockout only, with mouse lambda-type light chain being wild type instead of knockout. | Order | ||
| B6;129P2-Eltd<tm1Dge n>/H | Eltd1 | 3 | None. | Order From EMMA |
| Epc1<tm1aWtsi> | Epc1 | 18 | None. | Order From EMMA |
| C3H101H-Es3<c-nH> | Es3<c-nH> | 11 | Order | |
| Es3<c> | UN | |||
| Es3<b> | UN | |||
| B6;129P2-Esr2<tm1Dge n>/H | Esr2 | 12 | No visible phenotype. | Order From EMMA |
| 129S9/SvEvH-Evta/H | Evta | UN | White coat with non-agouti specking and occasional non-agouti patches. | Order From EMMA |
| B6NDen;B6N-Slc38a10< tm2a(EUCOMM)Wtsi>/H | Slc38a10<tm2a(EUCOMM )Wtsi> | 11 | Order From EMMA | |
| TgN(FLU)Ox(Fergie) | Order | |||
| C3H;C-Fer/H | Fers | 4 | Heterozygotes have abnormal hind limbs, vigourous touch escape and circling. | Order From EMMA |
| TgN(FLU)Ox(Fiona) | Order | |||
| FMLC-TM/12 | Statistically elevated levels of leptin & adiponectin after overnight fasted bleeds at 12wks of age with increased bodyweight. Bodyweight & adiponectin levels still elevated after an overnight fasted bleed at 16wks of age. After DEXA analysis: statistically increased bodyweight, fat mass & % body fat. | Order | ||
| C3H101H-Fnld/H | Fnld | X | Faint lined. | Order |
| C3H;C-Gsdma3<Fgn>/H | Gsdma3<Fgn> | 11 | Mice carrying this mutation show progressive hair loss. Weanlings show a typical ragged coat phenotype. Following this mice go through several cycles of hair loss and regrowth. Adult mice eventually become almost hairless with a small amount of hair around the snout. | Order From EMMA |
| FNOS2 | Circling, vestibular defects. Heterozygotes can be identified by mild head bobbing or circling behaviour. Mice with this behaviour usually show morphological changes in the inner ear. | Order From EMMA | ||
| Foxh1<tm1Jlw> | Foxh1<tm1Jlw> | 15 | Homozygous lethal at day 8 of gestation. | Order From EMMA |
| C3H-Foxq1<sa>/H | Foxq1<sa> | 13 | I=glossy coat when homozygous CON=glossy coat. | Order |
| FRAG 1 | Affects male fertility, males with two or more copies are sterile. | Order | ||
| Frag X | Order | |||
| Fragal (CEMO_A1) | Order | |||
| TgN(FLU)Ox(Freddie) | Order From EMMA | |||
| FT | Vps33a<bf> | 5 | Order | |
| Fgf5<go> | 5 | |||
| Tht | 5 | |||
| FTO-I367F | Fto | 8 | Order | |
| FTOKOB8-B6-ACTIN-FLP E | Order | |||
| C3H101H-Axin1<Fu-kb> /H | Axin1<Fu-kb> | 17 | Knobbly. | Order |
| funny feet | Small, abnormal limbs (short and stick like). | Order | ||
| FVB/N-Tg(ACTB-cre)2M rt/J | Tg(ACTB-cre)2Mrt | UN | This Cre recombinase strain is under the human beta actin gene promoter. This strain expresses Cre recombinase in all cells of the embryo by the blastocyst stage of development. | Order |
| G6pd<b> | Low activity of glucose 6 phosphate dehydrogenase. | Order | ||
| STOCK G6pdx<a-m1Neu> | G6pdx<a-m1Neu> | X | Low glucose-6-phosphate dehydrogenase-a activity. | Order From EMMA |
| B6;129P2-Galr2<tm1Dg en>/H | Galr2<tm1Dgen> | 11 | No visible phenotype. | Order From EMMA |
| Galr2 | 11 | |||
| Gammy (JU) | Club foot in one or both hind limbs. | Order | ||
| TgN(UminiG)Ox(Gareth ) | Order | |||
| C3.C-Gars<C201R>/H | Gars<C201R> | 6 | Mice heterozygous for this dominant mutation exhibit low limb tone, low grip strength and poor wire manoeuvrability. | Order From EMMA |
| TgN(UminiG)Ox(Gavin) | Order | |||
| 129-Elane<tm1(cre)Ro es>/H | Elane<tm1(cre)Roes> | 10 | Impaired innate immunity. | Order From EMMA |
| 129-Elane<tm1(cre)Ro es>Ctsg<tm1.1Roes>/H | Elane<tm1(cre)Roes> | 10 | Impaired innate immunity. | Order From EMMA |
| Ctsg<tm1.1Roes> | 14 | |||
| GENA287 | Heterozygotes are small at birth and maturity with striped coat. | Order | ||
| GENA 29 (Cross 3) | Kumba mouse can be belly spot, curly tail, or spina bifida. | Order | ||
| GENA381 | High Alkaline phosphatase, low cholesterols, distinguishable by blood testing. Some mutants are smaller and have a darker coat colour. | Order From EMMA | ||
| GENA394 | Impaired Glucose Tolerance (IGT). | Order From EMMA | ||
| GENA111 | Small at birth and weaning. Waddler behaviour. Rough coat. | Order From EMMA | ||
| C3H;C-Emx2<Pdo>/H | Emx2<Pdo> | 19 | Mice heterozygous for this mutation carry a dominant mutation that causes syndromic hearing loss and is possibly a novel mouse model of Leopard Syndrome. Currently known defects in affected mice include conductive hearing loss due to malformation of the ossicular chain and sensineural deafness due to an extra inner and outer row of stereocillia hair cellls in the cochlea. Heart defects are also suspected but have not been confirmed. | Order From EMMA |
| GENA187 | High locomotive activity and arousal activity in heterozygotes. | Order From EMMA | ||
| GENA221 | Heterozygotes are smaller than wildtypes. | Order From EMMA | ||
| C3H;C-Tuba1a<Jna>/H | Tuba1a<Jna> | 15 | Behavioural.High LMA. Heterozygotes are detected by measuring beam-splitting activity in LMA cages. Homozygosity has not been tested. GENA227 exhibits spontaneous hyperactivity in the absence of deafness and circling. | Order From EMMA |
| GENA316 | GENA316/+ animals have poor rota rod performance. | Order From EMMA | ||
| GENA323 | Large body size (+125%) and flaccid abdonimal tone. | Order From EMMA | ||
| GENA339 | Mice heterozygous for this mutation have cranofacial abnormalities observed as a broad head. | Order From EMMA | ||
| GENA344 | High pelvic elevation. | Order From EMMA | ||
| GENA353 | No response to touch escape. | Order From EMMA | ||
| GENA357 | Intermittent fits. | Order From EMMA | ||
| GENA360 | Low total choloesterol and HDL cholesterol. | Order From EMMA | ||
| GENA370 | Pmp22 | 11 | Fits and marked resting tremors. Mice heterozygous for this mutation exhibit hypomyelination abnormalities and have a marked resting tremor. | Order From EMMA |
| GENA371 | No tail. | Order | ||
| GENA377 | Heterozygote animals fall off the rota rod. | Order From EMMA | ||
| GENA396 | Mice heterozygous for this mutation have high blood glucose concentrations (hyperglycaemia). | Order From EMMA | ||
| GENA397 | Hypoglycaemic. | Order From EMMA | ||
| C3H.C-Scn8a<Clth>/H | Scn8a<Clth> | 15 | Cloth-ears mice show reduced acoustic startle response and mild hearing loss from about 30 days old. Tests indicate that the peripheral neural auditory pathway is impaired in these mutants, but that cochlear function is normal. Both homozygotes and heterozygotes display paroxysmal tremor episodes with behavioural arrest. Homozygotes demonstrate a milder continuous tremor during movement and rest. | Order From EMMA |
| GENA401 | Late onset deafness. | Order From EMMA | ||
| GENA100 | Mice carrying this mutation have dark pigmentation on their footpads and additional areas such as the ears and tail. Some litter mates may also be small. | Order From EMMA | ||
| GENA115 | Small at birth and weaning. Small testis. | Order From EMMA | ||
| GENA119 | circling. | Order | ||
| B6J.Cg-Bfc/H | Short domed head. | Order | ||
| C3H.Cg-Bfc/H | Bfc | 9 | Short broad head, dark pigmentation, abnormal gait and plevic elevation. Mice heterozygous for this mutation have abnormal facial pigmentation, cranofacial abnormalities observed as broad head and skeletal abnormalities observed as an abnormal gait and elevated pelvis. | Order From EMMA |
| C.Cg-Bfc/H | Bfc | 9 | Short broad head, dark pigmentation, abnormal gait and plevic elevation. Mice heterozygous for this mutation have abnormal facial pigmentation, cranofacial abnormalities observed as broad head and skeletal abnormalities observed as an abnormal gait and elevated pelvis. | Order |
| GENA127 | Heterozygotes have a pigmentation defect where the coat is lighter than agouti. | Order From EMMA | ||
| GENA135 | Mice carrying this mutation have an abnormal gait (hunched, jerky, darting), tail rattle, evidence of aggression in arena, vigourous touch escape response and tachycardia. | Order From EMMA | ||
| GENA140 | Small with short head. | Order | ||
| GENA143 | Abnormal gait and waddling movement. | Order From EMMA | ||
| GENA144 | Passive. | Order | ||
| GENA15 | Small, extra digit. | Order | ||
| GENA151 | High activity. | Order | ||
| GENA155 | Heterozygotes are small with elevated pelvic limbs. | Order From EMMA | ||
| GENA160 | Head shaking , belly spot, white toes. | Order From EMMA | ||
| GENA172 | GENA172/+ animals have white feet and a belly spot. | Order From EMMA | ||
| GENA185 | Dominant behavoiural mutant with high gait, balance problems and strong grip. | Order | ||
| C3H;C-Icst/H | Icst | 2 | Abnormal gait and iris corneal strands. | Order From EMMA |
| GENA200 | Heterozygotes have a reduced or absent toe pinch response and/or reduced grip strength in SHIRPA assessment. | Order From EMMA | ||
| GENA203/mod | GENA203 mod/+ have an extra digit on one hind limb. GENA203 mod/Spgl have extra digits on all four limbs. Both have bone abnormalities. | Order | ||
| GENA214 | Very active, circling, limb grasp, no toe pinch. | Order | ||
| GENA217 | Low ppi. | Order | ||
| GENA228 | Behaviour. Headweaving and Circling in heterozygotes. | Order From EMMA | ||
| GENA243 | Low Total and HDL cholesterol. | Order From EMMA | ||
| GENA250 | Low plasma alkaline phosphatase. | Order From EMMA | ||
| GENA26 | Low muscle tone, belly spot, white feet, short crinkly tail. | Order From EMMA | ||
| C3H.Cg-Zic2<Ku>/H | Zic2<Ku> | 14 | The Kumba mouse (also known as GENA29) has three possible phenotypes, belly spot, curly tail, or spina bifida. Arose because of looped tail and or ventral spotting. Rare (~2%) instances of spina bifida were also observed. Mutation maintained by backcrosses to C3H. The C3H background seems to decrease the penetrance of the visible heterozygous phenotypes. The homozygous mutation causes mid gestation lethality, with embryos exhibiting neural tube and other defects. | Order From EMMA |
| GENA31 | Heterozygote females have a stripey coat at 8 days indicative of X-inactivation. Hemizygous males do not survive. Phenotype of heterozygous females has not been characterised in detail. | Order From EMMA | ||
| GENA313 | Poor righting reflex and small. | Order From EMMA | ||
| GENA318 | Irritable at shirpa, kinky tail, high locomotive activity. | Order From EMMA | ||
| GENA321 | High Startle. Heterozygotes are detected by measuring response to 110 db tones. They are hyper responsive to sudden pulses of sound. The underlying cause may be neurological or behavioural. Homozygosity has not been tested to date. | Order From EMMA | ||
| GENA327 | High triglycerides. | Order | ||
| C3H;C-Alpl<Hpp>/H | Alpl<Hpp> | 4 | Mice with this mutation have low plasma alkaline phosphatase. | Order From EMMA |
| GENA342 | Headweaving/headbobbing and circling in heterozygotes. | Order | ||
| C3H;C-Gck<Gena348>/H | Gck<Gena348> | 11 | Mice heterozygous for this mutation have high blood glucose and increased body weight. | Order From EMMA |
| GENA350 | Abnormal gait, vigorous touch escape. | Order From EMMA | ||
| GENA359 | GENA359/+ animals have a lower left eye, blunt nose, craniofacial defect. | Order From EMMA | ||
| C3H;C-Flna<Dilp2>/H | Flna<Dilp2> | X | Dilated pupils in heterozygotes. | Order From EMMA |
| GENA382 | Animals from this stock have abnormally high levels of alanine transferase (ALT) and asparate tansferase (AST). | Order | ||
| GENA383 | Inherited abnormal high levels of plasma sodium and chloride. | Order From EMMA | ||
| GENA391 | Lipid and glucose perturbations. | Order From EMMA | ||
| GENA40 | Dark coat. | Order From EMMA | ||
| C3H;C-Rasgrf1<enu1H> /H | Rasgrf1<enu1H> | 9 | Small mice when inherited through an affected male-imprinting mutation. | Order From EMMA |
| GENA91 | Tremor. | Order From EMMA | ||
| C3H.Cg-Sho2/H | GENA93 animals have cranofacial abnormalities observed as shorthead. | Order From EMMA | ||
| TgN(UminiG)Ox(George ) | Order | |||
| TgN(UminiG)Ox(Gerald ) | Order | |||
| C3H/HeH-Gja8<No2>/H | Gja8<No2> | 3 | Cataract in lens nucleus, more severe in homozygotes. | Order From EMMA |
| C3H101H-Gli3<Xt>/H | Gli3<Xt> | 13 | Extra toes. | Order |
| C3H101H-Gli3<Xt-2H> | Gli3<Xt-2H> | 13 | Extra toes. | Order |
| 129S2.Cg-Gnas<tm2Kel >/H | Gnas<tm2Kel> | 2 | There is a behavioural phenotype: response to novel environments as measured through activity in various tasks. This targeted allele has been shown to represent a null for Nesp55 protein. | Order From EMMA |
| B6.Cg-Gnas<tm2Kel>/H | Gnas<tm2Kel> | 2 | There is a behavioural phenotype, response to novel environments as measured through activity in various tasks. | Order From EMMA |
| TgN(UminiG)Ox(Gordon ) | Order | |||
| C3H101H-Gpi1<c>/H | Gpi1<c> | 7 | Order | |
| C3H101H-Gpi1<a-m1H> | Gpi1<a-m1H> | 7 | Order | |
| Gpi1-s<TEM> | Gpi1<b> | UN | Order | |
| Gpi1<a> | UN | |||
| Gpi1<TEM> | UN | |||
| B6;129P2-Gpr56<tm1Dg en>/H | Gpr56 | 8 | None | Order From EMMA |
| 129-Gca<tm1Roes>/H | Gca<tm1Roes> | 2 | Minimal. | Order From EMMA |
| TgN(UminiG)Ox(Grant) | Order | |||
| B6NDen;B6N-Snip1<tm1 a(EUCOMM)Wtsi>/H | Snip1<tm1a(EUCOMM)Wt si> | 4 | Order From EMMA | |
| B6;129P2-Grm1<tm1Dge n>/H | Grm1 | 10 | No visible phenotype. | Order From EMMA |
| B6;129P2-Grm4<tm1Dge n>/H | Grm4 | 17 | No visible phenotype. | Order From EMMA |
| B6;129P2-Grm5<tm1Dge n>/H | Grm5 | 7 | No visible phenotype | Order From EMMA |
| B6;129P2-Grm8<tm1Dge n>/H | Grm8 | 6 | No visible phenotype | Order From EMMA |
| C3H101H-Gs/H | Gs | X | Greasy. | Order |
| GtRosa26LacZ<tm1Col> | No obvious phenotype. | Order From EMMA | ||
| B6J;C-Guth/H | Huntington’s disease, enhancer of tremor onset. | Order | ||
| Hba<c2> | Hba<c2> | UN | Order | |
| Hba<f> | UN | |||
| Hba<cm> | Hba<cm> | UN | Order | |
| Hba<f> | UN | |||
| Hbb<d3> | Hbb<d3> | UN | Order | |
| C3H101H-Hbb<d4>/H | Hbb<d4> | 7 | Order | |
| C3H101H-Hbb<d5>/H | Hbb<d5> | UN | Order | |
| Hbb<d6> | Hbb<d6> | UN | Order | |
| C3H101H-Hbb<d7>/H | Hbb<d7> | UN | Order | |
| B6N-Hbp1<not yet ass igned>/H | Hbp1 | 12 | Order From EMMA | |
| B6N;B6N-Herc3<tm1a(E UCOMM)Wtsi>/WtsiH | Herc3<tm1a(EUCOMM)Wt si> | 6 | None. | Order From EMMA |
| C57BL/6J-Nox3<het>/H | Nox3<het> | 17 | Heterozygotes can have abnormal circling behaviour & hyperactivity. Homozygotes also exhibit a subtle head tilt. | Order |
| Hira<neo> | Early embryonic lethality | Order | ||
| Histidinaemic | Grey | Order | ||
| 129-Foxa2<tm1Jrt>/H | Foxa2<tm1Jrt> | 2 | Homozygous lethal at day 8 of gestation. | Order From EMMA |
| HNF4 cre | Hnf4a | 2 | Homozygous lethal at mid gestation due to defects in liver formation. | Order From EMMA |
| Hox11 KO/unr5 | Hox11 KO produces spleenless mice. uNR5 causes truncation (deletion of C1 and C2) of IgM H-chain. | Order | ||
| Hoxa3<tm1(cre)Moon> | Hoxa3<tm1(cre)Moon> | 6 | Order | |
| C3H101H-Gnrh1<hpg>/H | Gnrh1<hpg> | 14 | Order | |
| Hprt | Order | |||
| C3H101H-Aifm1<Hq>/H | Aifm1<Hq> | X | Order | |
| C3H101H-Hr<hr>Ednrb< s>/H | Hr<hr> | 14 | Hairless. | Order |
| HSA-Mini George | Order | |||
| HSA-mini Grant | Order | |||
| STOCK hsh/H | hsh | 3 | hind shaker | Order |
| HSP27 WT High Copy L ine | No phenotype in transgenic carriers. | Order From EMMA | ||
| HSP27 WT Low Copy Li ne | No phenotype in transgenic carriers. | Order From EMMA | ||
| HSP27 WT PrP Promote r Line | No phenotype in transgenic carriers | Order From EMMA | ||
| HT | Gdf5<bp> | 2 | Order | |
| Pldn<pa> | 2 | |||
| Mlph<ln> | 1 | |||
| Ap3b1<pe-H> | UN | |||
| C3H101H-Hum/H | Heterozygotes have very dark stripe down the back, homozygotes very dark all over. | Order | ||
| B6NDen;B6N-Tnfaip1<t m1a(EUCOMM)Wtsi>/H | Tnfaip1<tm1a(EUCOMM) Wtsi> | 11 | Order From EMMA | |
| C3h101H-Hw/H | Small at birth and weaning, waltzing and circling phenotype. Homozygotes probably die before birth. | Order | ||
| Igfn1_KD1 | Order | |||
| IGT/10 | Double heterozygous mice have type II diabetes. | Order | ||
| B6;129P2-Il8ra<tm1Dg en>/H | Cxcr1<tm1Dgen> | 1 | No visible phenotype. | Order From EMMA |
| IM | Prnp | 2 | Dilute brown coat. | Order |
| C3H101H-In(1)5H | White toes and spotting. Animals tend to be small | Order | ||
| STOCK In(2)2H | A<w> | 2 | Phenotypic effect on agouti locus. | Order |
| As | 2 | |||
| STOCK In(2)5Rk | Pldn<pa> | 2 | black with a tan belly | Order |
| Pax1<un> | 2 | |||
| a<t> | 2 | |||
| C3H101H-In(5)9Rk | reduced fertility in both sexes | Order | ||
| STOCK In(X)IH | Order | |||
| STOCK In(X)3H | Eda<Ta> | X | Order | |
| Atp7a<Mo-blo> | X | |||
| In(YLS)Lub(Y<m>) | Order | |||
| B6NDen;B6N-Cyb561<tm 1a(EUCOMM)Wtsi>/H | Cyb561<tm1a(EUCOMM)W tsi> | 11 | Order From EMMA | |
| INH/17 | Trembler mutation with high stepping gait. | Order From EMMA | ||
| INH/18 | Trembler mutation with high stepping gait. | Order From EMMA | ||
| INH/6 | Heterozygous females are striped. Hemizygous males have no guard hairs, hair on tails, normal teeth, very little hair behind the ears. Homozygous females look like hemizygous males. | Order From EMMA | ||
| INH/8 | Trembler mutation (poor inheritance). | Order From EMMA | ||
| Invs<inv> | Invs<inv> | 4 | Homozygous embryos develop situs inversus. | Order From EMMA |
| Icst | Icst | 2 | Abnormal gait, iris-corneal strands. Heterozygotes have variable eye phenotypes - corneal opacity/bulging, iris-corneal adhesion, irregular pupil, cataracts, some appear to have secondary glaucoma. May have poor penetrance. | Order |
| C3H101H-Is(1;13)4H/H | Small at birth and weaning. | Order | ||
| STOCK Is(7;1)40H | males are sterile. | Order | ||
| C3H101H-Is(In7;X)1Ct /H | Order | |||
| C3H101H-Is(In7;X)1Ct -Xce<a>/H | Xic<a> | X | Non-random X-inactivation | Order |
| C3H101H-Is(In7;X)1Ct -Xce<b>/H | Xic<b> | X | Order | |
| Isl1<tm1(cre)Cos> | Isl1<tm1(cre)Cos> | 13 | Order | |
| Isl1<tm1(cre)Sev> | Isl1<tm1(cre)Sev> | 13 | Order | |
| STOCK a<18H>/H | a<18H> | 2 | Homozygotes are non-agouti with very dark pinna hairs. A/a<18H> looks wild-type. a/a<18H> look umbrous i.e. non-agouti with agouti hairs along side of body and on the belly. | Order |
| STOCK Dnahc11<iv>/H | Dnahc11<iv> | 12 | Situs inversus viscerum. | Order From EMMA |
| jas1 | Wavy coat and curly whiskers. | Order | ||
| C3H.Cg-Fbxo11<Jf>/H | Fbxo11<Jf> | 17 | Deaf. | Order From EMMA |
| 129P2/OlaHsd-Map3k1< Gt(YTC001)Byg>/H | Map3k1 | 13 | Full description available from Europhenome | Order |
| C3H101H-Plp1<jp>/H | Plp1<jp> | X | Order | |
| JPX | Glo1<b> | UN | Order | |
| Ldh2<b> | UN | |||
| Hk1<b> | UN | |||
| Sdh1<b> | UN | |||
| B6.A-Ush1g<js>/J | Ush1g<js> | 11 | Deafness. | Order |
| JU/FaCt-+<a> +<c> | Order | |||
| Ju/FaCt-+<c> | Order | |||
| C3H.Cg-Mecom<Jbo>/H | Mecom<Jbo> | 3 | Late onset deafness, extra digit, reduced body weight, craniofacial defect. | Order From EMMA |
| K10T+/- | Krt10<tm1Tmm> | 11 | K10T mice show a phenotype in the epidermis and in tongue, esophagus and forestomach. Homozygous pups die on the first day after birth from dehydration due to generalised blistering within the epidermis. Heterozygous mice look normal at birth and develop a progressive thickening of the skin and hyperkeratosis. Their skin is scaly. Heterozygotes breed normally. | Order From EMMA |
| B6;129P2-Kcnj15<tm1D gen>/H | Kcnj15 | 16 | Kir4.2 potassium channel knockout. Phenotype as yet undetermined | Order From EMMA |
| Khk-a<tm1.1Ls> | Order | |||
| Khk-N<tm1(neo)Ls> | Order | |||
| C3H101H-Kit<W-19H> | Kit<W-19H> | 5 | dominant spotting | Order |
| CBA/H-Kit<W-27H>/H | Kit<W-27H> | 5 | Dominant spotting. | Order |
| C3H-Kit<W-28H> | Kit<W-28H> | 5 | dominant spotting | Order |
| C3H-Kit<W-29H> | Kit<W-29H> | 5 | dominant spotting | Order |
| Kit<W-30H> | Kit<W-30H> | UN | dominant spotting | Order |
| C3H101H-Kit<W-31H>/H | Kit<W-31H> | UN | Dominant spotting. | Order |
| Kit<W-32H> | Kit<W-32H> | UN | Dominant spotting. | Order |
| Kit<W-33H> | Kit<W-33H> | UN | dominant spotting | Order |
| C3H101H-Kit<W-36H> | Kit<W-36H> | 5 | Dominant spotting. | Order |
| C3H101H-Kit<W-38H>/H | Kit<W-38H> | UN | dominant spotting | Order |
| C3H101H-Kit<W-bd>/H | Kit<W-bd> | 5 | White band in trunk region. | Order From EMMA |
| C3H101H-Kit<W-ct>/H | Kit<W-ct> | 5 | Cattanach's dominant spotting | Order |
| C3H.Cg-Kit<W-e>/H | Kit<W-e> | 5 | Heterozygotes have coat spots. Homozygosity is lethal. | Order From EMMA |
| C3H101H-Kit<W-sh>/H | Kit<W-sh> | 5 | Sash | Order |
| Kit<W-sh>l | Kit<W-shl> ?? | UN | Order | |
| C57BL-Kit<W-v>/H | Kit<W-v> | 5 | Viable dominant spotting | Order |
| C3H;C-Kit<W-39H> | Kit<W-39H> | 5 | Heterozygotes have a white belly spot and occasionally a white head blaze. Homozygotes have not been identified and they may die in utero | Order |
| C3H-Koa/H | Koa | 15 | Heterozygotes have hairy ears and muzzle, homzygotes are slightly more extreme. | Order |
| B6NDen;B6N-Fam117b<t m1a(EUCOMM)Wtsi>/H | Fam117b<tm1a(EUCOMM) Wtsi> | 1 | Order From EMMA | |
| C3H101H-Sox<lcc>/H | Sox2<lcc> | 3 | light coat circler | Order |
| C3H101H-Lct/H | Light coat. | Order | ||
| C3H;C-Lcl/H | Lcl | UN | Lens cloudy. Cataracts. Mice heterozygous for this mutation show progressive cataract formation, with total opacity at approximately 3 months. Mice homozygous for this mutation have small eyes and total lens opacity at 4-5 weeks. | Order From EMMA |
| STOCK Rb(6.15)1Ald-M ip<Cat-Lop>/H | Mip<Cat-Lop> | 10 | Lens opacity. | Order |
| C3H;C-Pax6<Leca1>/H | Pax6<Leca1> | 2 | Heterozygotes have a central indentation and may have small eyes, irregular pupils and lens corneal adhesions | Order From EMMA |
| C3H;C-Pax6<Leca2>/H | Pax6<Leca2> | 2 | Heterozygotes have small eyes, corneal opacities and cataracts. | Order From EMMA |
| C3H;C-Pax6<Leca3>/H | Pax6<Leca3> | 2 | Mutants may have central corneal opacity, small eyes, dilated pupils and lens-corneal adhesion. | Order From EMMA |
| Lepr<db> | Lepr<db> | 4 | Recessive misty mutation is present. Homozygotes become obese at 3-4 weeks of age. Elevation of plasma insulin begins at 10-14 days and of blood sugar at 4-8 weeks. Homozygotes die by 10 months of age. | Order |
| C3H101H-Li/H | Li | X | Lined. | Order |
| LII | Mcoln3<Va> | 3 | Order | |
| Gli3<Xt> | 13 | |||
| T | 17 | |||
| LIII | Cdh23<v> | 10 | Order | |
| Mlph<ln> | 1 | |||
| Hps1<ep> | 19 | |||
| Sgk3<fz> | 1 | |||
| Lim-1 (Lhx-1) | Lhx1<tm1Bhr> | 11 | Homozygous lethal at day 10 of gestation. | Order From EMMA |
| Line # 46 - Fused lo be | Order | |||
| Line # 48b - Unbranc hed | Fusion of cranal and medial lung lobes; kidneys are small, lack medulla; lacrimal glands have less epithelium branching | Order | ||
| LIVA | Tyrp1<b> | 4 | Order | |
| Tgfa<wa1> | 6 | |||
| Tyr<c-ch> | 7 | |||
| Myo5a<d> | 9 | |||
| Bmp5<se> | 9 | |||
| Ednrb<s> | 14 | |||
| a | 2 | |||
| LL | Gdf5<bp-H> | UN | limb - short legs and digits affected. | Order |
| Pldn<pa> | UN | |||
| Mlph<ln> | UN | |||
| LMWP3 | Low Molecular Weight Protein (LMWP) in the urine which is an indicator of proximal tubule dysfunction in the kidney. | Order | ||
| Lnk -/- | Order | |||
| Lo Moe | None. | Order From EMMA | ||
| C3H101H-Dync1h1<Loa> /H | Dync1h1<Loa> | 12 | Legs at odd angle. | Order From EMMA |
| C.Cg-Lpk/H | Lpk | UN | Short-limbed phenotype in both fore- and to a lesser extent hind-limbs. Mice have short limbs (achondroplasia). | Register Interest |
| C3H.Cg-Lpk/H | Lpk | UN | Short limbs (achondroplasia). | Order From EMMA |
| Loop tail | Vangl2<Lp> | 1 | Ltap<Lp>/+ mice exhibit a tail defect. Ltap<Lp>/Ltap<Lp> mice exhibit severe neural tube defect (die at birth). | Order |
| STOCK Lop4/H | Lop4 | 2 | Lens opacity. | Order |
| STOCK Lop6/H | Lop6 | UN | Lens opacity | Order |
| STOCK Lop9/H | Lop9 | UN | Order | |
| B6;129P2-Lphn2<tm1Dg en>/H | Lphn2 | 3 | None | Order From EMMA |
| LR8 | Hps6<ru> | 19 | Order | |
| Gdf5<bp> | 2 | |||
| Bmp5<se> | 9 | |||
| Hps5<ru2> | 7 | |||
| Myo5a<d> | 9 | |||
| a | 2 | |||
| Oca2<p> | 7 | |||
| Hps1<ep> | 19 | |||
| ls<rrw> | Edn3<ls-rrw> | UN | Homozygotes usually die before weaning but have a predominantly white coat with pigmental rump. | Order |
| B6NDen;B6N-Ttll4<tm1 a(EUCOMM)Wtsi>/H | Ttll4<tm1a(EUCOMM)Wt si> | 1 | Order From EMMA | |
| LVC | Egfr<wa2> | 11 | Jerker, homozygotes exhibit jerky behaviour. Spontaneous. waved 2, homozygotes have wavy fur. Spontaneous. pe<H>, homozygotes have a light coat. Spontaneous. mahoganoid, homozygotes have a dark coat. Spontaneous. | Order |
| Espn<je> | 4 | |||
| Mgrn1<md> | 16 | |||
| Ap3b1<pe-H> | UN | |||
| LVI | Kitl<Sl-gbH> | UN | Toes fused,(8) black coat,(8) belly spots,(10) light coat,(10) behavioural (18) | Order |
| Mc1r<E-so> | UN | |||
| M1073B | Embryonic lethal. | Order From EMMA | ||
| M1185B | Embryonic lethal | Order From EMMA | ||
| M1239B | Embryonically lethal | Order From EMMA | ||
| M1616B | Embryonic lethal | Order From EMMA | ||
| M1645B | Embryonic lethal | Order From EMMA | ||
| M241B | Embryonically lethal | Order From EMMA | ||
| M369B | Embryonic lethal | Order From EMMA | ||
| M412B | Embryonic lethal | Order From EMMA | ||
| M54B | Embryonic lethal | Order From EMMA | ||
| M624B | Embryonic lethal | Order From EMMA | ||
| M876B | Embryonically lethal | Order From EMMA | ||
| C3H101H-ma-Mcoln3<Va >/H | ma | 3 | Mcoln3<Va> heterozygotes are deaf mice that have variegated coats, they also circle and/or headtoss. ma/ma mice have scruffy coats. | Order |
| Mcoln3<Va> | 3 | |||
| C3H101H-Maf<tm1Glm>/ H | Maf<tm1Glm> | 8 | Homozygotes have eye defects, are small and shaky, and may die before adulthood. | Order |
| C3H-Maf<Ofl>/H | Maf<Ofl> | 8 | Heterozygotes-opaque flecks in lens; homozygotes- very small eyes, most die at birth through failure to feed, survivors small, trembly, and develop nephritis. Dominant cataract | Order |
| C3H101H-Maf<Ofl>/H | Maf<Ofl> | 8 | Order From EMMA | |
| Mafb<Krml-kr>;we; (K reisler) | we | 2 | Order | |
| Mafb<kr> | 2 | |||
| 129P2/OlaHsd-Mkrn1<G t(RRB087)Byg>/H | Mkrn1<Gt(RRB087)Byg> | 6 | No abnormal phenotype detected. | Order |
| TgN(DSPM36)1886OxAna t | Order | |||
| TgN(DSPM36)1892OxAna t | Order | |||
| MB | Order | |||
| MBT1 | Lack of marble burying. Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. | Order From EMMA | ||
| MBT2 | Low anxiety, marble mutant | Order From EMMA | ||
| MBT3 | Low anxiety, marble mutant. | Order From EMMA | ||
| MBTR2 | Lack of marble burying. | Order From EMMA | ||
| MBTR3 | Lack of marble burying. | Order From EMMA | ||
| MC-1 | Phenotypically normal | Order | ||
| B6;129P2-Mc2r<tm1Dge n>/H | Mc2r | 18 | No visible phenotype. | Order From EMMA |
| MCA/mdx | Order From EMMA | |||
| B;CBACa-Dmd<mdx>Tg(C KMM-tTA)A3Rhvh/H | Tg(CKMM-tTA)A3Rhvh | UN | MCK-tTA/mdx mice contain the muscle specific creatine kinase (MCK) promoter driving the tetracycline regulated transactivator (tTA). | Order From EMMA |
| Dmd<mdx> | X | |||
| Mcpt1<tm1Hrpm> | Lack of Mcpt-1 expression. | Order | ||
| C3H101H-Mgrn1<md-nc> /H | Mgrn1<md-nc> | 16 | nonagouti curly | Order |
| mdx | Dmd<mdx> | X | X-linked muscular dystrophy. | Order |
| STOCK Dmd<mdx-3Cv>/H | Dmd<mdx-3Cv> | X | Order | |
| Mesp1<tm2(cre)Ysa> | Mesp1<tm2(cre)Ysa> | 7 | Order | |
| C3H;C-Chd7<Mt>/H | Chd7<Mt> | 4 | Heterozygotes exhibit head weaving and circling behaviour. Homozygotes exhibit midgestational lethality possibly due to vascular defects seen in the anterior neural tube. | Order From EMMA |
| C3H101H-Kitl<Sl-10H> /H | Kitl<Sl-10H> | 10 | steel | Order |
| C3H101H-Kitl<Sl-12H> /H | Kitl<Sl-12H> | 10 | steel | Order |
| C3H101H-Kitl<Sl-13H> /H | Kitl<Sl-13H> | UN | Order | |
| C3H101H-Kitl<Sl-14H> /H | Kitl<Sl-14H> | UN | Steel. | Order |
| C3H101H-Kitl<Sl-15H> /H | Kitl<Sl-15H> | UN | Steel. | Order |
| C3H101H-Kitl<Sl-17H> /H | Kitl<Sl-17H> | 10 | steel | Order |
| C3H101H-Kitl<Sl-18H> /H | Kitl<Sl-18H> | 10 | steel | Order |
| C3H101H-Kitl<Sl-20H> /H | Kitl<Sl-20H> | UN | Steel. | Order |
| C3H101H-Kitl<Sl-21H> /H | Kitl<Sl-21H> | UN | Order | |
| C3H101H-Kitl<Sl-22H> /H | Kitl<Sl-22H> | UN | Steel. | Order |
| C3H101H-Kitl<Sl-23H> /H | Kitl<Sl-23H> | UN | Steel. | Order |
| C3H101H-Kitl<Sl-24H> /H | Kitl<Sl-24H> | UN | Steel. | Order |
| C3H101H-Kitl<Sl-25H> /H | Kitl<Sl-25H> | 10 | steel | Order |
| C3H101H-Kitl<Sl-26H> /H | Kitl<Sl-26H> | UN | Steel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia. | Order |
| Kitl<Sl-27H> | Kitl<Sl-27H> | UN | Steel, greyish fur, pale feet and tail with occasional head dots and belly spots. | Order |
| C3H101H-Kitl<Sl-29H> /H | Kitl<Sl-29H> | UN | Steel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia, no survival past a few days after birth. | Order |
| C3H101H-Kitl<Sl-30H> /H | Kitl<Sl-30H> | UN | Steel, greyish fur, pale feet and tail with occasional head dots and belly spots. | Order |
| C3H101H-Kitl<Sl-31H> /H | Kitl<Sl-31H> | UN | Steel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia. | Order |
| C3H101H-Kitl<Sl-32H> /H | Kitl<Sl-32H> | UN | Steel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia, high pre-implantation loss - homozygotes die early in development, some live foetuses were also anaemic. | Order |
| C3H101H-Kitl<Sl-33H> /H | Kitl<Sl-33H> | UN | Steel, greyish fur, pale feet and tail with occasional head dots and belly spots. Anaemia. | Order |
| Mgf<Sl-34H>, T(19;11 )75H | Kitl<Sl-34H> | UN | Order | |
| C3H101H-Kitl<Sl-8H>/ H | Kitl<Sl-8H> | 10 | Order | |
| C3H101H-Kitl<Sl-9H>/ H | Kitl<Sl-9H> | 10 | steel | Order |
| C3H101H-Kitl<Sl-pan> /H | Kitl<Sl-pan> | 10 | Steel-panda. | Order |
| C3H101H-cw-Bmp5<se>t k/H | cw | 9 | Kinky tail. | Order |
| tk | 9 | |||
| Bmp5<se> | 9 | |||
| GENA163 | Mitf<Mi-H> | UN | Microphthalmia. Dominant mutant with small eyes, Mi-like. Heterozygotes are paler, they have head and belly spots. Homozygotes are white with no eyes. | Order |
| B6N;B6N-Mier1<tm1a(E UCOMM)Wtsi>/WtsiH | Mier1<tm1a(EUCOMM)Wt si> | 4 | None. | Order From EMMA |
| Mitf<Mi-wh>, px | Mitf<Mi-wh> | 6 | het. light coated & light ears & sometimes a belly spot. hom. Mitf<Mi-wh> white with slight micropthalmia, Forelimbs often affected with absence of digets & sometimes ulna. Large foramen in scapula. All feet have epidermal papillae etc. | Order |
| Wnt7a<px> | 6 | |||
| MLO | c<62chH>/c<62chH> homozygotes have a grey coat colour, c/c<62chH> trans-heterozygotes have a cream coat colour and ruby coloured eyes. | Order From EMMA | ||
| C3H101H-Minute/H | Minute | 7 | Minute. | Order |
| MOD Fused Toes | Syndactyly | Order | ||
| TgN(DSPM36)1892OxAna t | Order | |||
| C3H;C-Mtu/H | Mtu | 12 | Kinky tail, deaf, belly spot. Heterozygotes exhibit abnormal tail morphology, are deaf, and have belly spots that are characteristic of neural crest defects. Homozygotes, do not appear to be viable, as they have an open neural tube. | Order From EMMA |
| C3H101H-Mdh1<am1H>/H | Mdh1<am1H> | 11 | Order | |
| TgN(DSPM36)1327OxAna t | Order | |||
| MR | Albino, rough kinked whiskers | Order | ||
| C57BL/6Apb-Zap70<mrt le>/Apb | Zap70<mrtle> | 1 | Identified by severe reduction in T cell numbers in blood. Zap70 protein expression of mrt/mrt thymocytes was 25% of +/+ thymocytes. Het mice, mrt/+ have normal levels of CD4+ and CD8+ thymocytes but Zap70 protein expression is two-fold lower. | Order From EMMA |
| B6.Cg-Mro<tm1H>/H | Mro<tm1H> | 18 | No visible phenotype. | Register Interest |
| Mta1<tm1aWtsi> | Mta1 | 12 | None | Order From EMMA |
| C3.Cg-Mfl/H | Order | |||
| MUHi | Long term growth selected line. | Order | ||
| MULi | Long term growth selected mouse line. | Order | ||
| MURB125 | Limbs and bones are shorter than normal | Order | ||
| MURB151 | Heterozygotes have light grey coat , darker grey points on ears, nose and tail. Can be classified at 2-3 days old as the pigmentation of the skin is visibly different. | Order | ||
| CAST/EiJH | Order | |||
| SPRET/EiJH | Order | |||
| MUT1096 | Small with broad, domed head. | Order | ||
| MUT1152 | Homozygous post-implantation lethal. Heterozygotes are small with cranial doming, pop eyes, distal nasal bone with occasional indications of cleft. | Order | ||
| MUT1154 | Small at birth and small at weaning with cranial doming, variably wide between eyes and shortened nasal passage. | Order From EMMA | ||
| MUT1264 | Craniofacial and behavioural mutant with distal low degree tail kink. Homozygous pre-implantation lethal. Heterozygotes have a flat skull, short, blunt tails with a low degree distal kink and some have white feet. Behavioural abnormalities include head bobbing and erratic behaviour but they can swim. Small at birth and weaning with a high incidence of exencephaly in fetuses. | Order From EMMA | ||
| MUT1275 | ear/ tail/ white spotting | Order | ||
| MUT1293 | Small at birth and weaning. Broad head, bulging eyes, some have ear problems, ie. A build up of cartilage. | Order From EMMA | ||
| MUT1305 | Craniofacial. Small, white feet, some domed heads, wide between eyes which may bulge. | Order From EMMA | ||
| MUT1397 | Tail kinks. | Order From EMMA | ||
| MUT1425 | Mutation causes typical chylous ascites-like symptoms - milky abdomen at birth and puffy feet and tail in older animals. | Order | ||
| MUT1454 | Small at birth and weaning, white feet, short kinky tail. Some have odd behaviour - swaying, leaning, head bobbing | Order | ||
| MUT1477 | milky abdomen at birth, small at weaning | Order | ||
| MUT1488 | Small at birth and weaning. They have small eyes, very few have domed heads, some have white toes | Order From EMMA | ||
| MUT1490 | Mutation causes typical chylous ascites-like symptoms - milky abdomen at birth and puffy feet and tail in older animals. | Order | ||
| MUT1544 | Small at birth with bruised type appearance. Bloody areas beneath the skin, most common around the belly and abdomen - some around the neck and back legs. Small at weaning, most have a domed head | Order From EMMA | ||
| MUT1556 | Small with white feet, some have belly spot. Some show head bobbing and blunt and/or kinky tails. | Order | ||
| MUT1602 | Small at birth and weaning with white hind feet, short tail and head bobbing. Mice have shorter kinky tails. They have waltzing/head bobbing behaviour. Some are small in size and have white feet. | Order From EMMA | ||
| MUT1679 | Mice are small at birth and weaning, they have white feet and shorter kinky tails. Some have domed heads i.e skeletal effects and some display behavioural abnormalities i.e head bobbing. Occasional nasal cleft. | Order | ||
| MUT1681 | Small with white feet. Tails commonly severely shortened, kinked or curled. Some have broad, deep, short head, often with nasal stripe | Order | ||
| MUT1696 | Small in size with head bobbing. Heterozygotes are small at birth and weaning with head bobbing. Size and behavioural mutation. Unlikely homozygotes survive as evidence of pre implantation loss. Best bred through the male as females behaviour makes them poor carers for their young. | Order | ||
| MUT1704 | Small at birth and weaning. Domed/pointy heads, some with fused toes.The original female was small at birth and weaning with fused hind toes, slightly domed head, whitish toes and tail tip. The offspring phenotype varied, many were small, the fusing of toes only involved the soft tissue not bone. These embryos were generated by IVF with MUT/1704.3d male; small with kink in tail at birth. Small and runty at weaning with dark coat, pointy face and closed eyes. | Order | ||
| MUT1756 | Offspring look normal until 6 weeks when fur becomes sparse, and thus classification prior to 6 weeks not possible in heterozygotes. Small at birth and weaning. Fate of homozygotes not yet determined. | Order | ||
| MUT921 | Key feature is a short broad head, wide between eyes, shortened nasal passage with occasional indication of cleft. White feet and belly spots also seen. Small at birth and weaning. Recovery at birth low due to prenatal loss of foetuses with more extreme head abnormality. | Order From EMMA | ||
| STOCK Muted<mu>/H | Muted<mu> | 13 | Muted. Lighter coat. | Order |
| MUTN212 | Circling, limb grasp & trunk curl. | Order | ||
| MUTN673 | Small, deaf. | Order | ||
| MUTN777 | Right eye missing, very active, circling | Order | ||
| MUTN873 | Small, deep set eyes, short face, nose bends to left, upper teeth bent back, nose crooked, hunched, high gait & pelvic elevation, no abdominal tone, slow heart rate. | Order | ||
| MUTS 1/14 | Small eye mutation | Order From EMMA | ||
| B6NDen;B6N-Mxra7<tm1 a(EUCOMM)Wtsi>/H | Mxra7<tm1a(EUCOMM)Wt si> | 11 | Order From EMMA | |
| Myl2<tm1(cre)Krc> | Myl2<tm1(cre)Krc> | 5 | Order | |
| Myo7a<sh1-9J> | Myo7a<sh1-9J> | 7 | Shaker. | Order |
| Myo5a<d-100H> | Bmp5<se-m> | UN | Order | |
| Myo5a<d-100H> | UN | |||
| Myo5a<d-50H> | Bmp5<se> | 9 | Order | |
| Myo5a<d-50H> | UN | |||
| Myo5a<d-51H> | Bmp5<se> | 9 | (fits?) opisthotonic lethal | Order |
| Myo5a<d-51H> | UN | |||
| Myo5a<d-53H> | Bmp5<se> | 9 | (fits?) opisthotonic lethal | Order |
| Myo5a<d-53H> | UN | |||
| Myo5a<d-82H> | Bmp5<se> | 9 | Order | |
| Myo5a<d-83H> | Bmp5<se> | 9 | (fits?) opisthotonic lethal | Order |
| Myo5a<d-83H> | UN | |||
| Myo5a<d-84H> | Bmp5<se> | 9 | (fits?) opisthotonic lethal | Order |
| Myo5a<d-84H> | UN | |||
| Myo5a<d-85H> | Bmp5<se> | 9 | (fits) opisthotonic lethal | Order |
| Myo5a<d> | 9 | |||
| Myo5a<d-85H> | UN | |||
| C3H101H-Myo5a<d-86H> /H | Bmp5<se> | 9 | (fits?) Opisthotonic lethal. | Order |
| Myo5a<d> | 9 | |||
| Myo5a<d-86H> | UN | |||
| Myo5a<d-88H> | Myo5a<d> | 9 | (fits?) opisthotonic lethal | Order |
| Bmp5<se> | 9 | |||
| Myo5a<d-88H> | UN | |||
| Myo5a<d-89H> | Myo5a<d> | 9 | Order | |
| Bmp5<se> | 9 | |||
| Myo5a<d-89H> | UN | |||
| Myo5a<d-90H> | Myo5a<d> | 9 | (fits?) opisthotonic lethal | Order |
| Bmp5<se> | 9 | |||
| Myo5a<d-90H> | UN | |||
| C3H101H-Myo5a<d-91H> /H | Bmp5<se> | 9 | Order | |
| Myo5a<d> | 9 | |||
| Myo5a<d-91H> | UN | |||
| Myo5a<d-92H> | Bmp5<se> | 9 | (fits?) opisthotonic lethal. | Order |
| Myo5a<d> | 9 | |||
| Myo5a<d-92H> | UN | |||
| Myo5a<d-93H> | Myo5a<d> | 9 | (fits?) opisthotonic lethal | Order |
| Bmp5<se> | 9 | |||
| Myo5a<d-93H> | UN | |||
| C3H101H-Myo5a<d-97H> /H | Myo5a<d> | 9 | Order | |
| Bmp5<se> | 9 | |||
| Myo5a<d-97H> | UN | |||
| Myo5a<d<105H> | Myo5a<d-105H> | UN | Order | |
| Myo5a<d<52H> | Myo5a<d-52H> | UN | Order | |
| C3H101H-Myo5a<d-58H> Bmp5<se>/H | Myo5a<d-58H> | UN | Homozygous lethal. | Order |
| Myo5a<d<61H> | Myo5a<d-61H> | UN | Order | |
| Myo5a<d<78H> | Myo5a<d-78H> | UN | Order | |
| Myo5a<d<80H> | Bmp5<se> | 9 | Order | |
| Myo5a<d-80H> | UN | |||
| CBB8-Myo7a<26SB> | Myo7a<26SB> | 7 | Shaker 1 allele. Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wildtypes are indistinguishable from each other.Homozygotes show no preyer reflex. These Myo7a mutants do have severe hearing and vestibular abnormalities. While their retinas do not show any anatomical degeneration, there have been reports of retinal abnormalities. | Order From EMMA |
| CBB8-Myo7a<3336SB> | Myo7a<3336SB> | 7 | Shaker. | Order From EMMA |
| Myo7a<sh1-4494SB> | Myo7a<4494SB> | 7 | shaker | Order From EMMA |
| Myo7a<sh1-4626SB> | Myo7a<4626SB> | 7 | Shaker. Deafness, headshaking, circling | Order From EMMA |
| Myo7a<sh1-6J> | Myo7a<sh1-6J> | 7 | Shaker. | Order |
| Myo7a<sh1-8165SB> | Myo7a<sh1-8165SB> | UN | shaker. Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wildtypes are indistinguishable from each other. Homozygotes show no preyer reflex. Homozygote females will not rear litters | Order |
| Myo7a<Sh1-816SB> | Myo7a<816SB> | 7 | Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wild types are not distinguishable from each other. Homozygotes show no preyer reflex | Order From EMMA |
| Myo7a<sh1> | Myo7a<sh1> | 7 | shaker | Order |
| TgN(DSPM36)1668OxAna t | Order | |||
| C3H101H-Nan/H | Nan | 8 | neonatal anaemia | Order |
| C3H;C-Nano/H | Nano | X | Heterozygotes have small narrow faces. With aging, they develop patches of white hairs on their back. Hemizygous males are presumed to die in utero. | Order From EMMA |
| B6.129P2-Nat2<tm1Esi m>/H | Nat2<tm1Esim> | 8 | None. | Order From EMMA |
| B6;129-Scn10a<tm3(cr e/ERT2)Jnw>/H | Scn10a<tm3(cre/ERT2) Jnw> | 9 | None observed (heterozygous Nav1.8-CreERT2 can express enough Cre to delete the floxed fragement, but it does not affect the expression of Nav1.8 in Nav1.8 positive neurons in DRG). | Order From EMMA |
| B6;129P2-Nek6<tm1Dge n>/H | Nek6 | 2 | No visible phenotype. | Order From EMMA |
| Nephertiti | No visible phenotype. Mice develop nephrotic range proteinuria at a young age and has abnormal liver histology, similar to Lafora body disease. | Order From EMMA | ||
| 129S/SvEvNimrH-Nespa s<tm1Jop>/H | Nespas<tm1Jop> | 2 | Heterozygotes with paternal inheritance of deletion die within 1-2 days of birth. Heterozygotes with maternal inheritance of deletion appear normal. | Order |
| B6NDen;B6N-Nipsnap1< tm1a(EUCOMM)Wtsi>/H | Nipsnap1<tm1a(EUCOMM )Wtsi> | 11 | Order From EMMA | |
| Nkx2-5<tm1(cre)Rjs> | Nkx2-5<tm1(cre)Rjs> | 17 | Order | |
| Nmnat1<tm2Cole> | None | Order | ||
| C3H-Crygb<nop>/H | Crygb<nop> | 1 | nuclear opacity. Dominant cataract | Order |
| No fur | Curly whiskers and progressive hair loss. | Order From EMMA | ||
| C3H;102-Cryge<No3>/H | Cryge<No3> | 1 | Nuclear opacity 3. Dominant cataract. | Order From EMMA |
| Nodal<tm3Rob> | Nodal<tm3Rob> | 10 | Het shows no phenotype, homozygous results in disrupted L/R patterning. | Order |
| NOD | Age related onset of diabetes. | Order | ||
| NPA31-B4 | Offspring inheriting the targeted construct paternally do not feed, are hypoactive and die within a few hours. | Order | ||
| C3H-Npp/H | Npp | 5 | nuclear-posterior polar opacity. Dominant cataract | Order |
| B6;129P2-Npy6r<tm1Dg en>/H | Npy6r | 18 | No visible phenotype. | Order From EMMA |
| B6;129P2-Nr1d2<tm1Dg en>/H | Nr1d2 | 14 | No visible phenotype. | Order From EMMA |
| C3H;102-Casr<Nuf>/H | Casr<Nuf> | 16 | Small flecks in lens nucleus, difficult to see in heterozygote, clearer in homozygotes. The Nuf mice also exhibit ectopic calcification. | Order From EMMA |
| NVPD | Order | |||
| Och, Re<wc> | Krt27<Re-wc> | 11 | Och, ochre. Re<wc>, wavy coat. | Order |
| Och | 4 | |||
| C3H101H-Gnas<Oedsml> /H | Gnas<Oedsml> | 2 | When inherited through the female, the offspring are oedematous. When inherited through the male, the offspring show postnatal growth retardation. | Order |
| C3H-Crygs<Opj>/H | Crygs<Opj> | 16 | Opaque fibre cell junctions. Dominant cataract. | Order From EMMA |
| STOCK Opdc/H | Opdc | 19 | Optic disc coloboma. Mutants have retinal vascular abnormalities and optic discs of unusual size. | Order From EMMA |
| B6NDen;B6N-Orc5l<tm1 a(EUCOMM)Wtsi>/H | Orc5l<tm1a(EUCOMM)Wt si> | 5 | Order From EMMA | |
| C3H101H-ostes/H | ostes | UN | Muscular dystrophy, small size and muscle wasting. | Order From EMMA |
| C.Cg-ostes/H | ostes | UN | Small with muscle tremor. | Order |
| P-Rex1 CE3/B6 | Functional neutrophil deficiency | Order | ||
| B6J.129-S100A10<tm1J nw>/H | S100a10<tm1Jnw> | 3 | None. | Order From EMMA |
| B6;129P2-P2rx6<tm1Dg en>/H | P2rx6 | 16 | No visible phenotype. | Order From EMMA |
| B6;129P2-P2ry12<tm1D gen>/H | P2ry12 | 3 | None | Order From EMMA |
| 129-Ncf1<tm1Hbd>/H | Ncf1<tm1Hbd> | 5 | Impaired innate immunity. | Order From EMMA |
| C3H101H-p<In(7p;Sox6 )100H> | Oca2<p-d> | 7 | Order | |
| In(7p;7Sox6)100H | 7 | |||
| p<55H> | Tyr<c-ch> | 7 | Order | |
| p<55H> | UN | |||
| C3H101H-Oca2<p-61H>/ H | p<61H> | UN | p<61>/p slightly darker than p/p | Order |
| p<65H> | p<65H> | UN | Coat and eyes of p<65>/p darker than p/p. Coat and eyes of p<65>/p<65> only slightly lighter than wild-type. | Order |
| C3H101H-Oca2<p-66H>/ H | p<66H> | UN | Order | |
| p<78H> | p<78H> | UN | p<78>/p looks like b/b. Coat and eyes of p<78>/p<78> only slightly lighter than wild type. | Order |
| Oca2<p-79H> | p<79H> | UN | Order | |
| C3H101H-Oca2<p-80H>/ H | p<80H> | UN | Order | |
| C3H101H-Oca2<p-81H> | Oca2<p-81H> | 7 | Phenotype of p<81H>/p is similar to p/p, homozygotes die pre-natally | Order |
| C3H101H-Oca2<p-82H> | Oca2<p-82H> | 7 | phenotype of p<82H>/p is similar to p/p, homozygotes die pre-natally | Order |
| p<83H> | p<83H> | UN | Order | |
| C3H101H-Oca2<p-84H> | Oca2<p-84H> | 7 | phenotype of homozygotes is similare to p/p | Order |
| p<85H> | p<85H> | UN | Order | |
| C3H101H-Oca2<p-86H> | Oca2<p-86H> | 7 | Phenotype similar to p/p | Order |
| p<87H> | p<87H> | UN | Order | |
| p<d> | UN | |||
| C3H101H-Oca2<p-88H> | Oca2<p-88H> | 7 | phenotype of homozygotes is similar to p/p | Order |
| p<91H> | p<91H> | UN | Order | |
| p<92H> | p<92H> | UN | Order | |
| C3H101H-Oca2<p-93H>/ H | p<93H> | UN | Order | |
| p<95H> | p<95H> | UN | Order | |
| C3H101H-Oca2<p-96H>/ H | p<96H> | UN | Order | |
| p<97H> | p<97H> | UN | Order | |
| C3H101H-Oca2<p-98H>/ H | p<98H> | UN | Order | |
| C3H101H-Oca2<p-99H>/ H | p<99H> | UN | Order | |
| C3H101H-Oca2<p-bs>/H | Oca2<p-bs> | 7 | p-black-eyed sterile | Order |
| p<cp>, p<bs> | Oca2<p-cp> | 7 | Coat colour same as p/p. p-black-eyed sterile, originally p<24>H,p<bs>/p<bs> viable but smallish, have slightly jerky behaviour, usually sterile & darker in colour than p<bs>/p<cp>, p<cp>/p<cp> usually die around birth from cleft palate, few have lived. | Order |
| Oca2<p-bs> | 7 | |||
| p<d>, p<25H> | Oca2<p-d> | 7 | p<d>/p<d> eyes light at birth, dark at weaning. Coat similar to b/b but less "orange" | Order |
| Oca2<p-25H> | 7 | |||
| p<d>, p<6H> | Oca2<p-d> | 7 | p<d>/p<d> eyes light at birth, dark at weaning. Coat similar to b/b but less "orange" | Order |
| Oca2<p-6H> | 7 | |||
| STOCK Oca2<p-dn>/H | Oca2<p-dn> | 7 | Eyes pink at birth but darken by weaning. Coat slightly darker than p/p. | Order |
| C3H101H-Oca2<p-dn>/H | Order | |||
| C3H101H-Oca2<p-un>/H | Myo5a<d> | 9 | pink-eyed unstable | Order |
| C3H101H-Oca2<p-x>/H | Oca2<p-x> | 7 | Eyes dark at birth and weaning, coat only slightly lighter than wild type | Order |
| B6NDen;B6N-Pa2g4<tm1 a(EUCOMM)Wtsi>/H | Pa2g4<tm1a(EUCOMM)Wt si> | 10 | Order From EMMA | |
| C3H-Paf/H | Paf | X | Patchy fur. | Order |
| B6;129P2-Pak2<tm1Dge n>/H | Pak2 | 16 | None | Order From EMMA |
| C3H101H-Pax3<Sp-1H> | Pax3<Sp-1H> | 1 | splotch | Order |
| C3H101H-Pax3<Sp-2H>/ H | Pax3<Sp-2H> | 1 | splotch | Order From EMMA |
| C3H101H-Pax3<Sp-4H> | Pax3<Sp-4H> | 1 | Order | |
| C3H101H-Pax3<Sp-5H> | Pax3<Sp-5H> | 1 | splotch | Order |
| C3H101H-Pax3<Sp-r>/H | Pax3<Sp-r> | 1 | splotch-retarded, spotting | Order From EMMA |
| Pax3<Sp>, Tyrp1<b-cH > | Pax3<Sp> | 1 | Splotch. | Order |
| Tyrp1<b-cH> | 4 | |||
| C3.D2-Pax6<Coop>/H | Pax6<Coop> | 2 | Heterozygotes have corneal opacity with iris anomaly and small eyes | Order |
| C3H;C-Pax6<Leca4>/H | Pax6<Leca4> | 2 | Mutants have small eyes, but not always corneal opacity (corneal opacity affects most other Pax6 mutants). Often have anterior cataract. | Order From EMMA |
| Pax6<Sey-Neu> | Pax6<Sey-Neu> | 2 | Small eye | Order |
| PC | a | 2 | Order | |
| Oca2<p> | 7 | |||
| Tyr<c-ch> | UN | |||
| PCE/JP | a<t> | 2 | Order | |
| Sox18<Ra> | 2 | |||
| Edn3<ls> | 2 | |||
| Myo5a<d> | 9 | |||
| Egfr<wa2> | 11 | |||
| Wnt3a<vt> | 11 | |||
| C3H101H-Slc40a1<Pcm> /H | Slc40a1<Pcm> | 1 | Red ears and feet. | Order From EMMA |
| B6;129P2-Pde2a<tm1Dg en>/H | Pde2a | 7 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde3a<tm1Dg en>/H | Pde3a | 6 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde4b<tm1Dg en>/H | Pde4b | 4 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde4d<tm1Dg en>/H | Pde4d | 13 | No visible phenotype. | Order From EMMA |
| B6;129P2-Pde8a<tm1Dg en>/H | Pde8a<tm1Dgen> | 7 | No visible phenotype. | Order From EMMA |
| CBA/H-Pdss2<kd>/H | Pdss2<kd> | 10 | Kidney disease. Homozygotes develop nephrosis recognizable at about 10 weeks of age by drinking, loss of weight, anaemia, and death usually at 5 to 7 months. | Order |
| PED-JP/16 | Order | |||
| C3H101H-Pedc/H | Pale ears, dark coat. Pre-implantation loss of homozygotes. | Order | ||
| PEDM/105 | Elevated plasma phosphate. | Order | ||
| PEDM/14 | Hyperglycaemia. Elevated plasma glucose at 16 and 24 weeks of age. No detection of glucose in the urine. | Order From EMMA | ||
| PEDM/15 | High anxiety, tremors, small at weaning. | Order From EMMA | ||
| PEDM/25 | This strain demonstrates late onset (>6 months of age) tremors and some individuals have a high nose-poking response in a behavioural test. | Order From EMMA | ||
| PEDM/29 | Highly active and demonstrates a high degree of anxiety | Order From EMMA | ||
| PEDM/32 | Albuminuria | Order | ||
| PEDM/35 | Hyperglycaemia and glycosuria. | Order From EMMA | ||
| PEDM/36 | Limb grasping, walks backwards, inactive | Order From EMMA | ||
| PEDM/41 | Deformed digits shortened limbs | Order From EMMA | ||
| PEDM/42 | Homozygotes have a belted white band of hair around the mouse middle. Their appearance is similar to that of the known mutation on Chromosome 15, Adamts20<bt> (Belted). | Order From EMMA | ||
| PEDM/83 | Short/long faces and small mis-shapen eye sockets. | Order | ||
| PEDM52 | Presumed homozygotes have spina bifida. | Order | ||
| PEDV/118 | Order | |||
| PEDV/119 | Order | |||
| PEDV/128 | Order | |||
| PEDV/146 | Dark skin in marble like patterns, slightly darker fur. | Order | ||
| PEDV/156 | Headbob & head tilt. | Order | ||
| Pge<1H> | pge1<H> | UN | Order | |
| C3H101H-pge<2H>/H | pge2<H> | UN | Order | |
| C3H101H-Pge<3H>/H | pge3<H> | UN | Order | |
| Pgk1<a> | Pgk1<b> | UN | Order From EMMA | |
| Pgk1<a> | UN | |||
| Pgm1<n1H> | Pgm1<c> | UN | Order | |
| Pgm1<n-H> | UN | |||
| Pgm1<n2H> | Pgm1<n2H> | UN | Order | |
| Pgm1<c> | UN | |||
| Pgm1<n3H> | Pgm1<n3H> | UN | Order | |
| Pgm1<c> | UN | |||
| Pgm1<n4H> | Pgm1<n4H> | UN | Order | |
| Pgm1<c> | UN | |||
| Pgm2<am> | Pgm2<am> | UN | Order | |
| Pgm2<a> | UN | |||
| C3H101H-Ph/H | Ph | 5 | White 'belt'. | Order |
| C3H101H-Ph<3H> | Ph<3H> | 5 | patch | Order |
| STOCK Phex<Gy>/H | Gy | X | gyro | Order |
| STOCK Phex<Hyp>/H | Phex<Hyp> | X | hypophosphatemia | Order |
| Pk3<r>, Pk3<b> | Pkm2<a> | UN | Order | |
| Pkm2<b> | UN | |||
| Pkm2<r> | UN | |||
| PKDBac Line2 | Hets appear normal. Homs are small and develop hind-limb dragging at 4-6 weeks old | Order | ||
| C57BL/6Apb-Ikzf1<Pls tc>/Apb | Ikzf1<plstc> | 11 | Embryonic lethal E15.5-17.5. Anaemia. Failure of normal erythroblast growth & differntiation in feotal liver. Expansion of myeloid cells. | Order From EMMA |
| C3H;C-Play41/H | Play41 | UN | Identified in circadian rhythm screen. Mutant mice demonstrate a long circadian period (24-24.5hr), and reduced activity. | Order From EMMA |
| C3H;C-Play50/H | Play50 | UN | Identified in circadian rhythm screen. Reduced bouts of wheel- running activity | Order From EMMA |
| C3H;C-Play63/H | Reduced bouts of wheel- running activity. | Order From EMMA | ||
| C3H.Cg-Play1/H | These mice have a higher than normal degree of daytime activity in a 12:12 light:dark cycle. | Order From EMMA | ||
| C(C3)-Play16/H | No entrainment response to light pulses given at CT16. | Order From EMMA | ||
| PLAY19 | Identified in circadian rhythm screen. Potentially no entrainment response to light pulses given at CT16 | Order From EMMA | ||
| C3H.Cg-Play22/H | Play22 | UN | Mice carrying this mutation show a low endurance of wheel running activity. Wheel running activity is about 10% of control animals. | Order From EMMA |
| C3H.Cg-Play31/H | Identified in a circadian rhythm screen. Wheel turning activity is dramatically reduced in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play32/H | Identified in a circadian rhythm screen. These mice have reduced bouts of wheel running activity in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play36/H | Play36 | UN | Identified by circadian rhythm screen. Mutant mice demonstrate an increased phase shift after light pulse. | Order From EMMA |
| C3H;C-Play40/H | Identified in circadian rhythm screen. Mutants have potentially no entrainment response to light. | Order From EMMA | ||
| C3H;C-Play42/H | Identified in a circadian rhythm screen. These mice have two sets of activity onsets when first exposed to constant darkness conditions. | Order From EMMA | ||
| C3H;C-Play44/H | Identified in circadian rhythm screen. Potentially shows a large entrainment response to light and phase advancement in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play46/H | Play46 | UN | Poor entrainment to light in 12:12 light dark: cycle. | Order From EMMA |
| C3H;C-Play47/H | Identified in circadian rhythm screen. These mice free run in a 12:12 light:dark cycle. | Order From EMMA | ||
| C3H;C-Play57/H | Play57 | UN | Identified in circadian rhythm screen. Mutant mice demonstrate a shorter cicadian wild type. | Order From EMMA |
| C3H;C-Play65/H | Changed period length after light pulse at CT16. | Order From EMMA | ||
| C3H;C-Play72/H | Reduced bouts of wheel running activity. | Order From EMMA | ||
| C3H;C-Play78/H | Potentially no entrainment response to light. | Order From EMMA | ||
| C3H;C-Play79/H | Poor entrainment response to light. | Order From EMMA | ||
| C3H;C-Play81/H | Long circadian period & poor entrainment response | Order From EMMA | ||
| C3H;C-Play82/H | This mutation was identified in a circadian rhythm screen. It shows reduced bouts of wheel-running activity. | Order From EMMA | ||
| Plcg2<tm>-383/Bcl2-3 6Tg | Plcg2 | 8 | B cell dysfunction. Homozygotes are infertile. | Order From EMMA |
| ple | Pale. | Order | ||
| C3H101H-Plp1<jp-rsh> /H | Plp1<jp-rsh> | X | Shivering/shaking of hind quarters. | Order |
| GENA300 | Late onset deafness | Order From EMMA | ||
| POMC-Cre | Order | |||
| Pomc-cre Z/EG | Order | |||
| B6;129P2-Prep<tm1Dge n>/H | Prep | 10 | None | Order From EMMA |
| 129P2/OlaHsd-Prnp/Pr nd<tm1Dwm>/H | Prnp/Prnd<tm1Dwm> | 2 | No phenotype in female mice. Male homozygotes are sterile. | Order |
| Prnp<a(108L_189V)> (DD) | No phenotype | Order | ||
| Pro-Cre | None. | Order From EMMA | ||
| PrP Chicken-repeats | Prnp<tm1Cwe> | 2 | The octameric repeat region of the mouse prion protein was replaced with the hexameric repeat region from the domestic chicken. The mice express mouse PrP at wild-type levels with correct membrane location and orientation but have an altered metal binding region. The mice have been generated to get a better understanding of prion diseases such as CJD in humans. | Order From EMMA |
| Ps | Tyrp1<b> | UN | Syndactyly, extra digit, webbing of soft tissue on feet. | Order |
| a<e> | UN | |||
| PT | Tyr<c-ch> | 7 | Order | |
| Ednrb<s> | 14 | |||
| Myo5a<d> | 9 | |||
| Tyrp1<b> | 4 | |||
| Bmp5<se> | 9 | |||
| Oca2<p> | 7 | |||
| PTP/H | Myo5a<d> | 9 | Order | |
| Tyrp1<b> | 4 | |||
| Gpi1<a> | 7 | |||
| Tyr<c-ch> | 7 | |||
| Hbb<s> | 7 | |||
| Bmp5<se> | 9 | |||
| Ednrb<s> | 14 | |||
| a | 2 | |||
| Oca2<p> | 7 | |||
| Car<2b> | UN | |||
| Pgm1<b> | UN | |||
| Hba<f> | UN | |||
| Es3<b> | UN | |||
| B6;129-Ptprc<tm1Holm >/H | Ptprc<tm1Holm> | 1 | Defective lymphocyte development, more severe in T lineage, severe combined immunodeficiency. | Order From EMMA |
| C3H101H-Wnt7a<px>/H | Wnt7a<px> | 6 | Sterility. Skeletal abnormalities, mainly forelimb abnormalities. Postaxial hemimelia, recessive. The forelimbs are regularly affected. There may be absence of digits 5, 4, and 3, & reduction or absence of the ulna. There is always a large oval foramen in the scapula. The hindlimbs are usually normal, but digit 5 may be absent, and occasionally the fibula is reduced. Mice with severally affected limbs tend to have an extra pair of ribs and a slight reduction in number of presacral vertebrae. Both sexes are sterile and show anomalies of the Mullerian ducts, including a partly or wholly double vagina and uncoiled oviducts in the female, and peristent Mullerian ducts in the male. | Order From EMMA |
| Qk<qk> | Qk<qk> | 17 | Homozygotes shake and tremble when walking. Males sterile. | Order |
| Quaver | Tremors. | Order | ||
| STOCK Rb(4.6)2Bnr-Rb (4.15)4Rma-Rb(6.15)1Ald-Adamts20<bt>/H | Adamts20<bt> | 15 | Order | |
| STOCK Rb(4.6)2Bnr-Rb (4.15)4Rma-Rb(6.15)1Ald-Tyrp1<B-lt>Adamts20<bt>/H | Adamts20<bt> | 15 | Order | |
| Tyrp1<B-lt> | 4 | |||
| STOCK Rb(2.8)6Rma-Rb (6.15)1Ald-Rb(9.19)163H/H | Order | |||
| STOCK Rb(1.15)2Ct Rb (2.18)6Rma Rb(6.13)3Rma Rb(11.16)2H/H | Order | |||
| rag1<tm1ES> | Rag1 | 2 | Order | |
| C3H;C-Rasgrf1<enu2H> /H | Rasgrf1<enu2H> | 9 | Small. | Order From EMMA |
| STOCK Rb(1.10)10Bnr | Order | |||
| Rb(1.15)2Ct ln | Order | |||
| STOCK Rb(1.2)5H | Order | |||
| STOCK Rb(1.3)1Bnr | Order | |||
| STOCK Rb(10.11)8Bnr | Heterozygous females give low frequencies of aneuploid fetuses | Order | ||
| STOCK Rb(11.13)4Bnr | Testis weight reduced in both homozygotes and heterozygotes. | Order | ||
| STOCK Rb(11.16)2H | Order | |||
| C3H101H-Rb(12.13)3Ct | Order | |||
| STOCK Rb(16.17)7Bnr | Reduced testis weight in homozygotes. | Order | ||
| STOCK Rb(16.19)1Bu/H | Order | |||
| STOCK Rb(2.17)11Rma | Order | |||
| STOCK Rb(2.17)4H | Order | |||
| STOCK Rb(2.18)6Rma | Order | |||
| C3H101H-Rb(4.14)8H | Order | |||
| STOCK Rb(4.15)4Rma | Order | |||
| C3H101H-Rb(4.16)10H | Order | |||
| STOCK Rb(4.18)3H | Order | |||
| STOCK Rb(4.6)2Bnr | Order | |||
| Rb(4.6)2Bnr, Rb(9.14 )6Bnr | Bmp5<se> | 9 | Order | |
| Tyrp1<b> | 4 | |||
| Tgfa<wa1> | 6 | |||
| Myo5a<d> | 9 | |||
| Ednrb<s> | 14 | |||
| STOCK Rb(5.15)3Bnr/H | Order | |||
| STOCK Rb(5.19)1Wh | Order | |||
| STOCK Rb(6.13)1H | Order | |||
| C3H101H-Rb(6.13)3Rma | Order | |||
| STOCK Rb(6.15)1Ald | Order | |||
| C3H101H-Rb(8.12)5Bnr | testis weight are reduced in both homozygotes and heterozygotes and the sperm count for the former is significantly lower | Order | ||
| Rb(8.19)1Ct | Order | |||
| STOCK Rb(9.14)6Bnr | Testis weights are reduced in both homozygotes and heterozygotes and sperm count compared to control males was approximately halved in the former. | Order | ||
| STOCK Rb(9.19)163H | Order | |||
| C3H101H-Rb(X.12)7H | Heterozygous females are fertile but hemizygous males are sterile | Order | ||
| STOCK Rb(X.2)2Ad | Order | |||
| STOCK Rb(X.9)6H | Order | |||
| C3H;C-Rky/H | Rky | UN | At 10 weeks of age, pups show a swim phenotype described as rocky, leaning and jerky. By 18 weeks of age mice develop a head-bobbing/circling cage phenotype. | Order From EMMA |
| REC/9 | Weak limb grasp, belly spot. | Order From EMMA | ||
| RECB/13 | Single fetus observed with severe neural tube defect; possibly polygenic defect | Order From EMMA | ||
| C3H.Cg-Tulp3<hhkr>/H | Tulp3<hhkr> | 6 | Homozygotes have spina bifida and oedema, and die at birth. | Order |
| Steap<Fred> | Steap3<fred> | 1 | Abnormalities in red blood cell size and shape. | Order From EMMA |
| Redeye | Homozygous mutant mice exhibit a range of eye defects including pale retinas, vascular defects & white structures present in the eye. | Order | ||
| RegIII Beta knockout | none | Order From EMMA | ||
| STOCK Mitf<Rorp>/H | Mitf<Rorp> | 6 | Dilute coat/ear/tail colour. Heterozygotes have pigment dilution, while homozygotes lack coat pigment, but retain eye(iris) pigment and do not have small eyes. | Order From EMMA |
| STOCK Rvm/H | Rvm | 14 | Retinal vascular abnormalities. | Order From EMMA |
| STOCK Rwhs/H | Rwhs | 11 | Retinal white spots. In heterozygotes, white spots appear on the retina from one month of age. They do not seem to reduce vision. | Order From EMMA |
| B6;129P2-Rgs5<tm1Dge n>/H | Rgs5<tm1Dgen> | 1 | No visible phenotype. | Order From EMMA |
| C3H101H-Ri/H | Ringed. | Order | ||
| Ricky | Order | |||
| RIII/Dk | Prn-i<n> | UN | Order | |
| RKS-XI | No overt phenotype. Believed to be a silent mutation of Pkd111. | Order | ||
| STOCK Rn/H | Rn | 14 | Rn heterozygotes have white or partly pigmented hairs throughout coat. Homozygotes are lighter than heterozygotes and are viable and fertile | Order |
| STOCK Rn<fkl> | Rn<fkl> | 14 | freckled | Order |
| B6NDen;B6N-Rnf7<tm1a (EUCOMM)Wtsi>/H | Rnf7<tm1a(EUCOMM)Wts i> | 9 | Full description available in Europhenome | Order From EMMA |
| C3H;C-Aff1<Rob>/H | Aff1<Rob> | 5 | Robotic and jerky gait. Heterozygotes exhibit small size, ataxia, adult-onset Purkinje cell loss, cataracts, reduced survival, and low fertility. | Order From EMMA |
| ROHi | Long term growth selected mouse line. | Order | ||
| ROLi | Long term growth selected lines. | Order | ||
| C3H101H-rst/H | rst | UN | rosette | Order |
| C3H101H-Hps5<ru2> | Hps5<ru2> | 7 | ruby-eye | Order |
| C3H101H-Rw/H | Rw | 5 | Rw (rump-white) is homozygote lethal. Heterozygotes have white hindlegs and tails and white fur on the posterior part of the abdomen. | Order From EMMA |
| Rw,Kit<W-bd> | Kit<W-bd> | 5 | No pigment in rump area | Order |
| Kit<W-v> | 5 | |||
| Rw | 5 | |||
| S1.2DEL | Loss of Igf2 imprinting. | Order From EMMA | ||
| S1.2NEO | Intra-uterine growth restriction (paternal transmission). | Order From EMMA | ||
| sa mu | Muted<mu> | 13 | sa: silky coat with a high sheen, mu/mu have fur of a muted brown colour. | Order |
| Foxq1<sa> | 13 | |||
| sa mu pe | Foxq1<sa> | 13 | satin, muted, pearl stock. | Order |
| Muted<mu> | 13 | |||
| Ap3b1<pe-H> | UN | |||
| SAA2 | None. | Order From EMMA | ||
| C3H;C-Sagg/H | Sagg | 1 | Heterozygotes have loose skin. | Order From EMMA |
| C57BL/6Apb-Rc3h1<san >/Apb | Rc3h1<san> | 1 | Autoimmune disease, ANA, lymphadenopathy, splenomegaly, hyper IgG, SLE. | Order From EMMA |
| SB1 | Reduced hearing by clickbox. | Order | ||
| SB2/1 | Reduced hearing | Order From EMMA | ||
| C3H101H-Sby<2H>/H | Curly whiskers/absent at birth. Sporadic lack of fur growth.Some growth retardation from birth | Order From EMMA | ||
| C3H101H-scb/H | scb | 8 | Scabby. | Order |
| STOCK Scr/H | Scr | 6 | Scruffy. | Order |
| B6;129P2-Scube3<tm1D gen>/H | Scube3 | 17 | No visible phenotype. | Order From EMMA |
| SCW | Severe immunodeficiency. | Order | ||
| STOCK Sd/H | Sd | 2 | Urogenital abnormalities | Order |
| SDL | Myo5a<d-l> | 9 | Dilute coat. The colour of d<l>/ d<l> is identical to that of d/d but the mice develop a severe neuro-muscular disorder characterised by convulsions and opisthotonas (arching upwards of the head and tail) and they die at about 3 weeks. | Order |
| Bmp5<se> | 9 | |||
| Myo5a<d> | 9 | |||
| C3H;C-Sbc/H | Sbc | 16 | Identified in circadian rhythm screen. These mice change their period length from normal to long after a light pulse is given at CT16 (circadian time). | Order From EMMA |
| C3H;C-Heph<Sla>/H | Heph<Sla> | X | Heterozygous females have striped coats. Males are small and pale at birth and most die within 1 week of birth. Females are classed at 8 days of age. Sla is an X linked dominant and classed as a harmful mutant due to lethality of males. | Order From EMMA |
| C3H101H-Pax6<Sey-3H> | Pax6<Sey-3H> | 2 | Small at birth and weaning with small eyes, white feet and sometimes a belly spot | Order |
| C3H101H-Pax6<Sey-H> | Pax6<Sey-H> | 2 | Small-eye. | Order From EMMA |
| 129-Foxp3<sf>/H | Foxp3<sf> | X | scurfy, scaliness first of tail later other parts of body, skin tight, eyelids open late, males usually die before / shortly after weaning, survivors small & sterile, small abdominal tetsis & lack scrotum. Occasional sf females are X/O resemble sf males. Similar human disease: Ichthyosis and Male Hypogonadism | Order From EMMA |
| C3H;C-Sfrp2<C50F>/H | Sfrp2<C50F> | 3 | Normal. | Order |
| B6J.Cg-Sfrp2<l153N>/ H | Sfrp2<I153N> | 3 | Order | |
| B6J.Cg-Sfrp2<l153N>/ H | No Overt Phenotype. Full description available from Europhenome | Order | ||
| B6.Cg-Sfrp2<C50F>/H | Sfrp2<C50F> | 3 | Order | |
| B6.Cg-Sfrp5<Q27STOP> /H | Sfrp5<Q27stop> | 19 | Order | |
| Sgd | Small at birth and weaning, progressive hairless (from 3 weeks of age) with accompanying thickinening of the skin | Order | ||
| Shby/+ | Shabby. Patchy coat, tail rough. Cyclic epilation. | Order | ||
| Sherbert | Order | |||
| C3H.Cg-Sfl/H | Sfl | 2 | Identified in circadian rhythm screen. Mice carrying this mutation have no phase shifting response to a light pulse given at CT16. | Order From EMMA |
| C3H.Cg-Sci/H | Sci | 8 | Identified in circadian rhythm screen. Short circadian period of wheel-running activity (22.5 hrs rather than 23.5 hrs). Wheel running activity is about 10% of control animals. | Order From EMMA |
| Shp2CS x DO11.10 L1 | Characterisation of the phenotype is still in progress, but the line displays amplified cytokine secretion in response to antigenic challenge | Order | ||
| Shp2CS x DO11.10 L5 | Characterisation of the phenotype is still in progress, but the line displays amplified cytokine secretion in response to antigenic challenge | Order | ||
| Shp2CSxB10.BR Line 1 | Characterisation of phenotype still in progress but line displays defective primary immune responses to T-dependent antigen and amplified cytokine secretion in response to antgenic challenge. | Order From EMMA | ||
| C3H;C-Sic/H | Sic | 7 | Sickly . Classed as harmful. Heterozygotes are small and sickly. Mutation has not been tested for homozygosity. The Sickly mice are marginally smaller than wildtype sibs at birth and dramatically smaller (<50%) at weaning. The nature of this growth defect has yet to be investigated. Heterozygous mice are also prone to infection. | Order From EMMA |
| SIG (Position Testin g Stock chr.6) | Grid2<Lc> | 6 | Mitf<Mi-wh> is semidominant. The homozygotes are viable white mice, the eyes are pink at birth. The heterozygotes have light sandy coats and belly spots. Grid2<Lc> is homozygous lethal, the heterozygotes have swaying hindquarters and jerky up and down movement. Sig is homozygous lethal, the heterozygotes are blind, the eyes are open at birth, some exhibit hydrocephaly. | Order |
| Mitf<Mi-wh> | 6 | |||
| Sig | 6 | |||
| C3H101H-skimp/H | skimp | 7 | Order | |
| C3H;C-Jag1<Slalom>/H | Jag1<Slalom> | 2 | These mice exhibit head weaving and shaking behaviour. | Order From EMMA |
| Slc38a4<tm2Kel>/Delt aCG1A | None, a minor effect on term weight. | Order From EMMA | ||
| B6;129P2-Slc7a10<tm1 Dgen>/H | Slc7a10<tm1Dgen> | 7 | No visible phenotype. | Order From EMMA |
| C3H101H-Pou3f4<Slf>/ H | Pou3f4<Slf> | X | sex-linked fidget | Order |
| Slip | Order | |||
| C3H.Cg-Sgh/H | Sgh | 4 | Mice carrying this mutation demonstrate a low endurance of wheel running activity which is reduced to about 10% of control values. | Order From EMMA |
| Smad 2 D2 | None | Order From EMMA | ||
| Smad 2 FL | Smad2 | 18 | Embryonic lethal at day 8.5 dpc. | Order From EMMA |
| Smad 2 SF | Smad2 | 18 | Homozygous lethal at day 8.5. | Order From EMMA |
| Smad 2 T3 | Smad2 | 18 | Approx 50% of homozygotes are embryonic lethal at 15d, remainder are viable as adults. | Order From EMMA |
| Smad8 conditional | None | Order From EMMA | ||
| Smad8 LacZ | Smad9<tm1Rob> | 3 | None | Order From EMMA |
| C3H101H-Sme/H | Sme | UN | Reduction in size of pinna and often irregular in shape | Order |
| SMN E134K Transgenic | None. | Order From EMMA | ||
| SMN2 low | Tg(SMN2)89Ahmb | UN | Mice that are homozygous for the targeted mutant Smn1 allele and carry the SMN2 transgene exhibit symptoms and neuropathology similar to patients afflicted with type I proximal spinal muscular atrophy (SMA) but die at P6. (See Monani 2000 HMG 9 333-339). Mice homozygous for Smn1-/-, in the absence of SMN2 would die before birth. Heterozygotes for the knockout show no phenotype. | Order |
| Smn1<tm1Msd> | 13 | |||
| SMNDelta5 | None. | Order From EMMA | ||
| SMNDelta5-SMN2Low | Rescues post natal lethality of SMN2 low strain | Order From EMMA | ||
| SOCS-6 | Socs6<tm1Dlk> | 18 | 10% increased body weight & increased insulin sensitvity. | Order From EMMA |
| sooty foot | soo | 2 | Order | |
| Sox4<m91Ark> | Sox4<m91Ark> | 13 | Embryonically lethal. | Order From EMMA |
| GENA203 | Polydactyly. | Order From EMMA | ||
| C3H.Cg-Celsr1<Scy>/H | Celsr1<Scy> | 15 | Mice carrying this mutation exhibit circling behaviour. | Order From EMMA |
| C57BL-Spnb4<qv-3J>/H | Spnb4<qv-3J> | 7 | Heterozygotes apppear normal, homozygotes have locomotor instability, pronounced quivering, deafness. Homozygote males are sterile. | Order |
| Ssm | shaker small | Order | ||
| Ssy | small syndactyly | Order | ||
| C3H101H-Nsdhl<Str-1H >/H | Nsdhl<Str-1H> | X | striated | Order From EMMA |
| C3H101H-Nsdhl<Str-2H | Nsdhl<Str-2H> | X | striated | Order |
| C3H;C-Strg/H | Strg | X | Striped and greasy. | Order |
| STOCK Sts<->/H | Order | |||
| STOCK Myo6<sv>/H | Myo6<sv> | 9 | Order | |
| Svc (GENA 291) | Col4a1<Svc> | 8 | Small with vacuolar cataract | Order |
| C3H101H-Dync1h1<Swl> /H | Dync1h1<Swl> | 12 | Sprawling, abnormal posture and locomotion from defective position sense mainly affecting hind limbs, myelination deficient, deficiency of sensory receptors, spindles virtually absent from hind limbs. | Order From EMMA |
| SWR/Ola Hsd | Tyr<c> | 7 | Order | |
| Sxr | Eda<Ta-33H> | X | Order | |
| C3H101H-Tp(Y)1Ct<Sxr -b>/H | Tp(Y)1Ct<Sxr-b> | Y | Order | |
| sy<a> | Shaker with syndactylism Albany. | Order | ||
| B6;129-Sycn<tm1Rja>/ H | Sycn<tm1Rja> | 7 | Pancreatic secretion compromised. | Order From EMMA |
| C3H101H-T(10;13)199H | Order | |||
| C3H101H-T(10;18)18H | Order | |||
| T(10;18)18Hdl | Order | |||
| C3H101H-T(11;13)41Ad | Order | |||
| T(11;13)41Ad cross 2 | Order | |||
| C3H101H-T(11;13)56H | Order | |||
| C3H101H-T(11;19)42H | Order | |||
| C3H101H-T(13;14)69H | Order | |||
| T(14;15)6Ca hr | Order | |||
| CBA/H-T(14;15)6Ca | Order | |||
| T(1;10)73H | Order | |||
| C3H101H-T(1;12)52H | Order | |||
| STOCK T(1;13)70H | Order | |||
| JUN-T(1;2)5Ca | Order | |||
| C3H101H-T(1;4)71H | Order | |||
| C3H101H-T(1;6)42Ad | Order | |||
| C3H101H-T(1;7)49H | Order | |||
| C3H101H-T(1;8)63H | Order | |||
| C3H101H-T(2;11)30H | Order | |||
| T(2;11)30H - cross 4 | Order | |||
| C3H101H-T(2;14)48H | Order | |||
| C3H101H-T(2;15)45Ad/ H | Order | |||
| STOCK-T(2;16)28H | Order | |||
| STOCK-T(2;19)68H | Order | |||
| C3H101H-T(2;3)24H | Order | |||
| C3H101H-T(2;4)13H | Order | |||
| C3H101H-T(2;4)1Ca | Order | |||
| T(2;4)1Go | Order | |||
| STOCK T(2;4)1Sn | Order | |||
| T(2;5)72H | Order | |||
| C3H101H-T(2;6)7Ca | Order | |||
| T(2;8)26H | Order | |||
| STOCK T(2;8)2Wa/H | Order From EMMA | |||
| T(2;9)11H | Order | |||
| C3H101H-T(3;10)61H | Order | |||
| C3H101H-T(3;12)58H | Order | |||
| C3H101H-T(3;19)25Ad | Order | |||
| C3H101H-T(3;8)56Ad | Order | |||
| C3H101H-T(4;10)Hsc76 H/H | Head shaker, circling. | Order | ||
| C3H101H-T(4;12)47H | Order | |||
| C3H101H-T(4;5)46H | Order | |||
| C3H101H-T(4;6)77H/H | Homozygotes are sometimes infertile. | Order | ||
| C3H101H-T(4;6)77H-Mi tf<Mi-wh>/H | Mitf<Mi-wh> | 6 | Homozygotes sometimes infertile. | Order |
| T(4;8s)36H | Order | |||
| STOCK T(4;9)45H | Order | |||
| C3H101H-T(5;11)57H | Semi-sterile. | Order | ||
| C3H101H-T(5;12)31H | Order | |||
| STOCK T(5;13)264Ca | Order | |||
| C3H101H-T(5;7)30Ad | Order | |||
| C3H101H-T(6;12)32H | Order | |||
| C3H101H-T(6;13)6Ad | Order | |||
| T(6;14)39H | Order | |||
| STOCK T(6;7)51H | Order | |||
| C3H101H-T(6;8)2Ad | Order | |||
| STOCK T(7;11)40Ad/H | Order | |||
| STOCK T(7;11)65H | Reciprocal translocation | Order | ||
| C3H101H-T(7;13)7Ad | Order | |||
| C3H101H-T(7;15)9H | Heterozygotes are semi-sterile. | Order | ||
| C3H101H-T(7;16)67H | Order | |||
| STOCK T(7;19)145H | Male sterile. | Order From EMMA | ||
| C3H101H-T(9;10)62H | Order | |||
| STOCK T(9;17)138Ca | Order | |||
| C3H101H-T(In1;5)44H | Order | |||
| C3H101H-T(X;11)38H | Order | |||
| C3H101H-T(X;4)37H | Order | |||
| STOCK T(X;7)3Neu | Order | |||
| C57BL/6Apb-Lcp2<twm> /Apb | Lcp2<twm> | 11 | Few naïve CD4+ and CD8+ T cells, autoimmunity, 5fold decrease in DP Tcells. Defects in positive selection & reduced negative thymocyte selection, hypergammaglobulinemia and hyper-IgE. | Order From EMMA |
| STOCK T<21H>/H | T<21H> | 17 | Effects like brachyury | Order From EMMA |
| C3H101H-T<22H> | T<22H> | 17 | T<22H>/t<6> males have enhanced transmission ratio | Order |
| C3H101H-T<24H>/H | T<24H> | UN | Brachyury. | Order |
| C3H101H-T<25H>/H | T<25H> | UN | brachyury, sometimes slightly small mice with shortened, kinky tails. Males breed satisfactorily but females show impaired transmission producing few T<25H> offspring which have low viability. Homozygote presumed lethal. | Order |
| T<26H> | T<26H> | UN | brachyury | Order |
| C3H101H-T<29H> | T<29H> | 17 | Order | |
| C3H101H-T<30H> | T<30H> | 17 | Order | |
| C3H101H-T<31H> | T<31H> | 17 | Short tails | Order |
| C3H101H-T<32H>/H | T<32H> | 17 | Heterozygotes - short tail, homozygotes - lethal. | Order |
| C3H101H-T<33H> | T<33H> | 17 | short tails. Homozygotes lethal. | Order |
| C3H101H-T<34H> | T<34H> | 17 | Heterozygotes - short tail, Homozygotes - lethal. | Order |
| C3H101H-T<36H> | T<36H> | 17 | Short tails | Order |
| STOCK t<6>/H | t<6> | 17 | Taillessness with T | Order |
| C3H101H-T<c-2H> | T<c-2H> | 17 | tailless | Order |
| C3H101H-T<c>/H | T<c> | 17 | T<c>/+ and T<c>/t<h7> tailless. T<c>/T<c> lethal, like T/T but more severely affected | Order From EMMA |
| C3H101H-t<h17> | t<h17> | 17 | Order | |
| t<h18> t<h2> | t<h18> | 17 | Gives tailless with T. Homozygotes for t<h18> are lethal. t<h18> carries distal distortion D2 and t<h2> carries responder R. | Order |
| t<h2> | 17 | |||
| STOCK t<h20> | t<h20> | 17 | Order | |
| STOCK t<h44> | t<h44> | 17 | T/t<h44> tailless | Order |
| STOCK t<h49> | t<h49> | 17 | Order | |
| STOCK t<h50> | t<h50> | 17 | Order | |
| STOCK t<h51> | t<h51> | 17 | Order | |
| t<h51>t<h18> | t<h18> | 17 | Lethal when homozygous. | Order |
| t<h51> | 17 | |||
| t<lowH> | 17 | |||
| C3H101H-t<h57> | t<h57> | UN | Order | |
| STOCK t<h7> | t<h7> | 17 | Order | |
| t<h7m2> | t<h7m2> | UN | tailess with T | Order |
| t<h7m> | t<h7m> | UN | Tailless with T, homozygous viable. | Order |
| T<21H> | UN | |||
| STOCK T<hp>/H | T<hp> | 17 | Order | |
| t<hr15> | t<hr15> | UN | Tailess | Order |
| t<hr1> | t<hr1> | UN | Tailless | Order |
| t<hr4> | t<hr4> | UN | Tailless | Order |
| t<low2H> | t<low2H> | UN | Order | |
| t<low3H> | t<low3H> | 17 | Order | |
| STOCK t<lowH> | t<lowH> | 17 | Order | |
| t<low2H> | UN | |||
| STOCK t<lub2>/H | t<Lub2> | 17 | Order | |
| STOCK t<s6>/H | t<s6> | 17 | Order | |
| STOCK t<w32>/H | t<w32> | 17 | Order | |
| C3H101H-t<w32m>/H | t<w32m> | UN | Order | |
| t<x507> | t<x507> | UN | Tailess | Order |
| tf<t> | UN | |||
| Ta<10H> | Eda<Ta-10H> | UN | Tabby. | Order |
| C3H101H-Eda<Ta-23H> | Eda<Ta-23H> | X | Order | |
| Ta<23H> Xce<c> Pgk1< a> | Eda<Ta-23H> | X | Order | |
| Xic<c> | X | |||
| Pgk1<a> | UN | |||
| C3H101H-Eda<Ta-25H> | Eda<Ta-25H> | X | tabby | Order |
| C3H101H-Eda<Ta-26H> | Eda<Ta-26H> | X | tabby, has a hairy tail | Order |
| C3H101H-Eda<Ta-27H>/ H | Eda<Ta-27H> | UN | Tabby. The males have hairless tails. | Order |
| C3H101H-Ta<28H>/H | Eda<Ta-28H> | UN | Tabby. The males have hairless tails. | Order |
| C3H101H-Eda<Ta-29H> | Eda<Ta-29H> | X | tabby, males have hairless tails | Order |
| C3H101H-Eda<Ta-30H> | Eda<Ta-30H> | X | tabby | Order |
| C3H101H-Eda<Ta-32H> | Eda<Ta-32H> | X | tabby | Order |
| C3H101H-Eda<Ta-33H> | Eda<Ta-33H> | X | tabby, hairy tail and the teeth do not need cutting | Order |
| C3H101H-Ta<35H>/H | Eda<Ta-35H> | UN | Tabby, males have hairless tails and are bald behind the ears. | Order |
| C3H101H-Eda<Ta-36H>/ H | Eda<Ta-36H> | UN | Tabby. | Order |
| Ta<37H> | Eda<Ta-37H> | UN | tabby | Order |
| C3H101H-Eda<Ta-38H>/ H | Eda<Ta-38H> | UN | Tabby. | Order |
| C3H101H-Eda<Ta-39H>/ H | Eda<Ta-39H> | UN | Tabby. | Order |
| Ta<44H> | TA<Fa> like ie heterozygous females-striped, Hemizygous males-weak teeth, no guard hairs, bald tails, very little hair behind ears. | Order From EMMA | ||
| C3H101H-Tal/H | Tal | 14 | Heterozygotes cannot easily be identified at birth but can be classified at weaning. The feet are held in an abnormal position, there is soft tissue syndactylism involving digits 2,3, and to a lesser degree 4, and there is often overgrowth and twisting of the toenails. The forefeet are less obviously affected than the hindfeet. Homozygotes are more severely affected with extreme shortening of the phalanges and significant reduction to the metatarsals. The tail shows a kinking to form a hook near the tip. | Order |
| TAS16 | Curly tail | Order From EMMA | ||
| TAS2 | Belly spot, head spot, white feet (variable). | Order From EMMA | ||
| TAS4 | Multiple white spotting over entire body | Order From EMMA | ||
| TAS6 | Belly spot, white feet, head spot | Order From EMMA | ||
| tcl<6> | tcl<6> | UN | Order | |
| Tcx | Striped coats in females,greasy coat in males. | Order | ||
| C3H101H-Ebp<Td>/H | Ebp<Td> | X | Tattered. | Order From EMMA |
| tde | Grxcr1<pi-tde> | 5 | insertional mutation Tasmanian devil | Order |
| TERB-54 | Possible modifier of Huntingdon's disease. Affected mice present with gait problems. | Order | ||
| TERB-56 | Possible modifier of Huntingdon's Disease. Affected mice have intermittent paralysis in one hind leg. Culled at 12 weeks | Order | ||
| TERB-57 | Order | |||
| C3H101H-Tesa/H | Tesa | UN | Mice carrying this mutation are deaf, have short tails and exhibit circling behaviour. | Order From EMMA |
| TESOD-20 | This stock is a model for ALS (Amyotrophic Lateral Sclerosis), a progressive, usually fatal neurogenerative disease caused by the degeneration of motor neurons. They are carrying a modifier ENU induced mutation that makes their whole phenotype more severe. Mice were dying at around 30-35 weeks of age with a severe ALS phenotype so therefore they are usually humanely killed once they get one hind limb paralysed. | Order | ||
| Tesod-36 | Order | |||
| TESOD-37 | Order | |||
| TFH | Order | |||
| TFH/H | T | 17 | Shorter tail, blunt. | Order From EMMA |
| tf | 17 | |||
| TFL | Order | |||
| C3H101H-Cacna1a<tg>/ H | Cacna1a<tg> | 8 | Tottering phenotype. Homozygotes have wobbly gait from 3-4 weeks and intermittant seizures. Heterozygotes appear normal. | Order |
| Tg(-214VpreB1-huCD12 2)F133Lmb | No known effects | Order From EMMA | ||
| Tg(5'lambda 5-huCD25 )82Lmb | No known effects | Order | ||
| Tg(CMV-tetO-CFTR)TC3 5CH | None | Order From EMMA | ||
| Tg(Leftb-cre)1Hmd | Tg(Leftb-cre)1Hmd | UN | Order | |
| Tg(Nmnat1) 7104Cole | None. | Order | ||
| B6J;CBA-Tg(RP1-309F2 0)48Kel | Order From EMMA | |||
| Tg(RP21-340H11)29Kel | Mild hyperglycaemia in neonates, mildly impaired glucose tolerance post weaning. | Order From EMMA | ||
| CBB6-Tg(runx1/MTG8)I CH10Fc/H | Order | |||
| CBB6-Tg(runx1/MTG8)I CH11Fc/H | Order | |||
| CBB6-Tg(runx1/MTG8)I CH12Fc/H | Order | |||
| CBB6-Tg(runx1/MTG8)I CH7Fc/H | Order | |||
| CBB6-Tg(runx1/MTG8)I CH8Fc/H | Order | |||
| CBB6-Tg(runx1/MTG8)I CH9Fc/H | Order | |||
| Tg(Sox2-cre)1Amc | Tg(Sox2-cre)1Amc | UN | Order | |
| Tg(T-cre)1Lwd | Tg(T-cre)1Lwd | UN | Order | |
| Tg(TH1-TauV337m)T39 | Tg(Thy1-MAPT*V337M)1 Godt | UN | Development of abnormal tau phosphorylation & aggregation within the brain, as seen in Alzheimer's & other tauopathies. Highly discrete & specific age-dependent cognitive changes including memory impairment & impaired impulse control. | Order |
| Tg(Wnt1-cre)11Rth | Tg(Wnt1-cre)11Rth | UN | Order | |
| 129-Tgfbr2<tm1Roes>/ RoesH | Tgfbr2<tm1Roes> | 9 | Order From EMMA | |
| STOCK Epo<Tg(SV40T/E po)134.3LCPjr>/H | Epo<Tg(SV40T/Epo)134 .3LCPjr> | UN | Homozygotes have incomplete epo deficiency and are anaemic. | Order From EMMA |
| Tg(bTGTRfs)1Vkc | Order | |||
| TgN(CEB1GEN)-G | None | Order | ||
| TgN(CEB1GEN)-H | None | Order | ||
| TgN(CEB1GEN)-I | None | Order | ||
| B6C3-Tg(HD82Gln)81Db o/H | Tg(HD82Gln)81Dbo | UN | Onset of abnormal gait and tremors at 3 months. Fail to gain weight from 2 months. | Order |
| B6CB-Tg(PMP22)C1Clh | Tg(PMP22)C1Clh | UN | Order | |
| B6;CB-Tg(PMP22)C22Cl h/H | Tg(PMP22)C22Clh | UN | Shaking & unsteady gait. | Order From EMMA |
| B6CB-TgN(PMP22)C58Cl h | Order | |||
| B6CB-Tg(PMP22)C61Clh | Order | |||
| B6CB-Tg(PMP22)JP18Cl h | Order | |||
| (B6xCB)F2-Tg(PMP22)M Y41Clh | Tg(Pmp22)My41Clh | UN | Shaky & unsteady gait. | Order |
| B6CB-Tg(pUHG16)JU2Cl h | None | Order | ||
| B6CB-Tg(yCFTR)A10Clh /H | None | Order | ||
| B6CB-Tg(yCFTR)T30Clh /H | Order | |||
| B6CB-Tg(yCFTR)T57Clh /H | None. | Order | ||
| TgNmnat1 line 881 | None. | Order | ||
| C57BL/6S-Hnrpll<thdr >/Apb | Hnrpll<thdr> | 17 | A marked reduction in the no. of peripheral T cells, especially naïve CD4 & CD8 cells, and poor survival of thunder T cells upon adoptive transfer. The T cells are hyperactivated. | Order From EMMA |
| Tiffany | Mice exhibit eye defects. Sections of the lens diffract light differently. | Order | ||
| C57BL/6Apb-Lig4<tiny >/Apb | Lig4<tiny> | 8 | Small in size, no CD8 cells or B cells, TCR Tg appears to rescue T cells. Similar to human SCID. | Order From EMMA |
| Tis11b<tm1mt> | Day 9 embryonic lethal | Order | ||
| C3H101H-Tks/H | Tks | 9 | tail kinks | Order |
| B6;129P2-Tln1<tm1Cri t>/CritH | Tln1<tm1Crit> | 4 | Order From EMMA | |
| 129/SvEv-Tln1<tm1Cri t>/CritH | Tln1<tm1Crit> | 4 | Order | |
| Tlss | Thymo lymph sarcoma susceptibility. | Order | ||
| TM/45 | Abnormal response to Intraperitoneal Glucose Tolerance Test at 24 weeks of age. | Order From EMMA | ||
| TM/47 | Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. | Order From EMMA | ||
| TM/58 | These mice have an abnormal walking posture, appearing as though the hips are fused. Histological examination shows this to be a muscular phenotype. | Order From EMMA | ||
| TM/59 | Abnormal response to Intraperitoneal Glucose Tolerance Test at 12 weeks of age. Fasting hyperinsulinaemia at 16 weeks. Mice are significantly heavier than wildtype at 12 and 16 weeks of age. | Order From EMMA | ||
| TM/60 | Abnormal response to Intraperitoneal Glucose Tolerance Test at 12 weeks of age. Abnormal IPGTT and fasting hyperinsulinaemia at 16 weeks. Mice are significantly heavier than wildtype at 12 and 16 weeks of age. | Order From EMMA | ||
| TM13 | Head bobbing | Order From EMMA | ||
| TM2 | Behavioural/low anxiety phenotype | Order | ||
| TM4 | High T60 in intraperitoneal glucose tolerance tests. | Order From EMMA | ||
| B6;129P2-Tmem67<tm1D gen>/H | Tmem67 | 4 | No visible phenotype | Order From EMMA |
| TMR/10 | Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. | Order From EMMA | ||
| Tmsb4x<tm1Tnr> | Tmsb4x | X | B-cell defect. | Order From EMMA |
| To | Cat5<To2> | 10 | Order | |
| C3H101H-Lim2<To3>/H | Lim2<To3> | 7 | Total opacity, dominant cataract. | Order From EMMA |
| B6;129P2-Tpcn1<tm1Dg en>/H | Tpcn1 | 5 | No visible phenotype. IVF/1772.1k - short tail, IVF/1772.1m- tail kink. | Order From EMMA |
| TPL | Order | |||
| Tpm1<tm1aWtsi> | Tpm1 | 9 | None. | Order From EMMA |
| C3H.Cg-Pmp22<Tr-1H>/ H | Pmp22<Tr-1H> | 11 | Tremors with seizures. Tremors, muscle weakness. | Order From EMMA |
| C3H;C-Pmp22<Tr-2H>/H | Pmp22<Tr-2H> | 11 | Tremors, muscle weakness. | Order From EMMA |
| Trembly | Muscular dystrophy, small size, muscle wasting. | Order | ||
| C3H101H-Trf<bm>/H | Trf<bm> | UN | Order | |
| B6;129P2-Trpc4<tm1Dg en>/H | Trpc4 | 3 | No visible phenotype. | Order From EMMA |
| B6;129P2-Trpc6<tm1Dg en>/H | Trpc6 | 9 | No visible phenotype. | Order From EMMA |
| C3H101H-Tsk2/H | Tsk2 | 1 | Heterozygotes can be recognised at 1 to 2 weeks of age by a tightness of the skin across the shoulders when picked up. The mice are fully viable and fertile. | Order From EMMA |
| Tyr<c-37Hch> | Tyr<c-37Hch> | UN | (hair - colour, eye - colour) chinchilla | Order |
| Tyr<c-38Hch | Tyr<c-38Hch> | UN | (hair - colour, eye - colour) chinchilla | Order |
| C3H101H-Tyr<c-40H>/H | a | 2 | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| Tyr<c-40H | UN | |||
| Tyr<c-42H> | Tyr<c-ch> | 7 | (hair - colour, eye - colour, behaviour - sight) albino. | Order |
| Tyr<c-42H> | UN | |||
| Tyr<c-43H> | Tyr<c-ch> | 7 | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| Tyr<c-43H> | UN | |||
| C3H101H-Tyr<c-44H> | Tyr<c-44H> | 7 | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| C3H101H-Tyr<c-45H> | Tyr<c-45H> | 7 | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| C3H101H-Tyr<c-46H> | Tyr<c-46H> | 7 | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| C3H101H-Tyr<c-47H>/H | Tyr<c-47H> | UN | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| Tyr<c-49Hch> | Tyr<c-49Hch> | UN | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| Tyr<c-50H> | Tyr<c-50H> | UN | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| Tyr<c-51H> | Tyr<c-51H> | UN | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| Tyr<c-54Hch> | Tyr<c-54Hch> | UN | (hair - colour, eye - colour) chinchilla | Order |
| Tyr<c-55H> | Tyr<c-ch> | 7 | (hair - colour, eye - colour, behaviour - sight) albino | Order |
| Tyr<c-55H> | UN | |||
| C3H101H-Tyr<c-em>/H | Tyr<c-em> | 7 | (hair - colour, eye - colour) chinchilla extreme mottled. Extreme dilution of coat. | Order From EMMA |
| C3H101H-Tyr<c-m>/H | Tyr<c-m> | 7 | (hair - colour, eye - colour) chinchilla mottled | Order |
| C3H101H-Tyr<c-r>/H | Tyr<c-r> | 7 | (hair - colour, eye - colour) ruby-eyed | Order |
| C3H101H-Tyrp1<b-55H> /H | Tyrp1<b-55H> | UN | (hair - colour) brown. | Order |
| C3H101H-Tyrp1<b-65H> /H | Tyrp1<b-65H> | UN | (hair - colour) brown | Order |
| C58-Tyrp1<B-lt>/H | Tyrp1<B-lt> | 4 | (hair - colour) heterozygotes have light underfur, homozygotes almost white hair except tips | Order |
| C3H101H-Ufde/H | Affected individuals have one or both ears low set and reduced in size. | Order | ||
| C3H101H-Lnp<Ul>/H | Lnp<Ul> | 2 | Ulnaless. | Order |
| UMLC-TM/12 | Statistically lowered body weight & plasma levels of glucose after an overnight fast at 12 & 16 wks of age. DEXA at 14 wks: decreased body weight, lean & total tissue, BMD & BMC. | Order | ||
| UMLC-TM/6 | Statistically elevated body weight & plasma levels of glucose, leptin & adiponeptin after an overnight fast at 12 & 16 wks of age. In addition elevated levels of insulin at 16wks of age. DEXA at 14wks: increased fat mass & % fat. | Order | ||
| C57BL/6Apb-Card11<un m>/Apb | Card11<unm> | 5 | The mice make poor antibody responses, and as they age they develop atopic dermatitis and hyper-IgE, with red itchy ears & weepy eyes, progressing to badly eroded skin from itching. | Order From EMMA |
| UTR/mdx (TEX) | This stock contains a tetracyclin inducible utrophin transgene when crossed with MCK-tTA mice. | Order From EMMA | ||
| Utrn<+/-> | Utrn<+/-> | UN | Abnormal neuromuscular junction morhpology. | Order |
| Utrn<-/-> | Utrn<-/-> | UN | Abnormal neuromuscular junction morhpology | Order |
| v<ALB> | Cdh23<v-Alb> | 10 | Waltzer Albany. | Order From EMMA |
| C3H;C-Vng/H | Vng | 5 | Small. One low ear. | Order From EMMA |
| VANIMMA | Under investigation: not severely immunocompromised. | Order | ||
| B6.129P2-Vnn1<tm1Pna >/H | Vnn1<tm1Pna> | 10 | Order | |
| B6.129P2-Vnn1<tm1Pna >/H | Vnn1<tm1Pna> | 10 | Order | |
| VAV-NPM/ALK | Mice develop lymphoid tumours from 6 months of age. | Order From EMMA | ||
| B6;129P2-Vipr1<tm1Dg en>/H | Vipr1 | 9 | No visible phenotype | Order From EMMA |
| C3H101H-Vm/H | Heterozygote males have a high probability of being sterile. Visceral myopathy. Off white coat colour, intestinal problems in some animals. Males may be sterile. Older animals develop tremors. Homozygotes die soon after birth with major kidney abnormalities. | Order | ||
| VM/Dk | Order | |||
| STOCK Kit<W>/H | Kit<W> | 5 | Dominant white spotting | Order |
| B6129-Tg(Wap-cre)117 38Mam | Tg(Wap-cre)11738Mam | UN | There is no abnormal phenotype. Albino, black or white bellied Agouti. | Order |
| Ward Wines 5 | Small increase in kidney size, possible late-onset cyst formation. | Order | ||
| C3H;C-Egfr<Wa5>/H | Egfr<Wa5> | 11 | Small eyes, eyes open at birth, curly whiskers and coat. Heterozygotes have open eyelids and curly whiskers at birth. The first coat has a crimped appearance and subsequent coats are wavy/rough. | Order From EMMA |
| wavy coat | Mice carrying this mutation have a wavy coat. | Order From EMMA | ||
| C3H;C-Whto/H | Whto | 7 | White toes. Heterozygous Whto mice display white belly spots and/or white toes. Homozygotes would appear to be embryonic lethal. | Order From EMMA |
| STOCK Whrn<wi>/H | Whrn<wi> | 4 | Deaf, head tossing and circling. Whirler. | Order From EMMA |
| Wnt2b | No visible phenotype | Order | ||
| C3H101H-Wnt3a<vt>/H | Wnt3a<vt> | 11 | (1) vestigial tail (2) Homozygotes have very short tails, varying form complete absence to about half normal length. | Order |
| STOCK Wnt3a<vt>Foxq1 <sa>Muted<mu>/H | Muted<mu> | 13 | Vestigial tail. | Order |
| Wnt3a<vt> | 11 | |||
| Foxq1<sa> | 13 | |||
| C3H101H-Eef1a2<wst>/ H | Eef1a2<wst> | 2 | Wasted homozygotes can be recognised at 20 days of age by tremor and uncoordinated body movements. They develop progressive paralysis and do not survive beyond 30 days. The wasted heterozygotes have normal viability. Also contains Ra. The ragged heterozygotes have thin, ragged coats. The homozygotes are almost naked and are semi-lethal. | Order |
| C3H101H-Xic<a> | Xic<a> | X | Order | |
| Xce<a> Pgk1<a> | Pgk1<a> | UN | Order | |
| Xce<a> | UN | |||
| Xce<b> Atp7a<Mo-blo> | Xce<b> | UN | Order | |
| Atp7a<Mo-blo> | UN | |||
| Xce<b> Pgk1<a> | Xce<b> | UN | Order | |
| Pgk1<a> | UN | |||
| Xce<b>, Ta<Fa> | Xce<b> | UN | Order | |
| Xce<c> Pgk1<b> | Xce<c> | UN | Order | |
| Pgk1<b> | UN | |||
| Xla | Anaemia in females, seen at birth to 2 days old and may be small. | Order From EMMA | ||
| XO | Eda<Ta> | X | Order | |
| Atp7a<Mo-blo> | X | |||
| C3H101H-Xs/H | Xs | 7 | Extra-toes spotting | Order From EMMA |
| Y<d-1> | Order | |||
| Y<d-2> | Order | |||
| Y<d-3> | Order | |||
| Y<d-5> | Order | |||
| Y<d-6> | Order | |||
| Y<d4> | Order | |||
| Y<dr1> | Order | |||
| Y<dr2> | Order | |||
| Y<dr3> | Order | |||
| Y<dr4> | Order | |||
| Y<dr5> | Order | |||
| C57BL/6J-Chr Y<POS>/ H | May show XY sex reversal and hermaphroditism. | Order | ||
| C3H;C-Ankrd11<Yod>/H | Ankrd11<Yod> | 8 | Craniofacial, broad face. Heterozygotes (Ankrd11<Yod>/+) have readily distinguishable craniofacial features. Further to this, abnormal bone morphology including an abnormally small growth plate, negligible chondrocyte hypertrophy and a dramatically reduced zone of woven bone formation have been detected. | Order |
| C3H.Cg-Ankrd11<Yod>/ H | Ankrd11<Yod> | 8 | Craniofacial, broad face. Heterozygotes (Ankrd11<Yod>/+) have readily distinguishable craniofacial features. Further to this, abnormal bone morphology including an abnormally small growth plate, negligible chondrocyte hypertrophy and a dramatically reduced zone of woven bone formation have been detected. | Order From EMMA |
| YZ15 | Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. Unlike low copy number lines, the Igf2 LacZ gene does not show appropriate reciprocal imprinting in YZ15 mice as it is expressed from both parental alleles. | Order From EMMA | ||
| YZ17 | Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. Deletion of the intergenic region with Cre recombinase results in partial (mesoderm specific) reactivation of Igf2 LacZ expression following maternal transmission. | Order From EMMA | ||
| YZ20 | Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over?expressing H19 is not fully characterised. | Order From EMMA | ||
| YZ46 | Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. | Order From EMMA | ||
| YZ8 | Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. The imprinted H19 gene is only expressed when transmitted through the maternal germline. After paternal transmission the gene is repressed. The Igf2 LacZ gene shows appropriate reciprocal imprinted behaviour (paternal allele specific expression, maternal repression). | Order From EMMA | ||
| ZA1 | a<e> | 2 | Order | |
| Tyrp1<b> | 4 | |||
| Tyr<c-ch> | 7 | |||
| Dock7<m> | 4 | |||
| C3H101H-a<t>Tyrp1<b- cH>Tyr<c-ch>/H | a<t> | 2 | Order | |
| Tyr<c-ch> | 7 | |||
| Tyrp1<b-cH> | 4 |