AllEmbryo onlySperm onlyCre onlyTet only
Strain NameGene/Allele SymbolChrPhenotypeAvailability
(beta)-globin (mu)MT
<-/->
(mu)MT<-/-> produces IgM H-chains.Order
B6J.129-Kcnj16<tm1Sj
tu>/H
Kcnj16 11Disrupted Kir 5.1 Potassium Channel. Phenotype not known at this point.Order
101/H Inbred strain.Order
102/H Wild type, inbred strain.Order
10Bob Affected mice head-bob, circle and walk backwards.Order
129S9/SvEvH-Nodal<tm
1Rob>/H
Nodal<tm1Rob> 10Heterozygote viable. Homozygote early developmental lethal (does not gastrulate).Order
129P2/OlaHsd The mice have yellow coats and late onset severe vacuolation in brain (700+ days).Order
129P2/OlaHsd-Prnp<tm
2Edin>/H
Prnp<tm2Edin> 2No expression of the Prnp gene. Abnormalities in synaptic transmission, circadian rhythm and sleep. Increased susceptability to oxidative stress and copper toxicity. Cellular phenotypes in T cell activation.Order From EMMA
129S/SvEvNimrH Inbred strain.Order
129S9/SvEvH Wildtype.Order
129/terSv - TgN(Hbb-
b) 83Clo/Ws
Tg(Hbb-b1)83Clo UNReiterated transgene is detectable by DNA in situ hybridisation.Order
129/terSv-TgN(Hbb-b1
)83Clo, Pax6<Sey/+>/Ws
Pax6<Sey> 2Reiterated transgene is detectable by DNA in situ hybridisation.Order From EMMA
Tg(Hbb-b1)83Clo UN
129S9/SvEvH.B6-a/H a 2Black coat colour. The non-agouti locus from C57BL/6J has been bred to congenicity on a 129S9/SvEvH background. This stock is homozygous for non-agouti (a/a).Order
129-Fgfr3<tm1.1Aomw>
/Aomw
Fgfr3<tm1.1Aomw> 5All homozygous males, some homozygous females and some heterozygous males develop an abnormal skull phenotype sometimes with malocclusion, and may be smaller in size. The phenotype is not fully penetrant. Refer to publication for further information: PMID:19086028. Order From EMMA
A/JH Inbred strain.Order
A.129P2-Nat2<tm1Esim
>/H
Nat2<tm1Esim> 8No overt phenotype.Order From EMMA
C3H101H-a<13H>/H a<13H> UN(hair - colour) non-agouti-13-Harwell, umbrous effect.Order
C3H101H-a<16H>a<l>/H a<16H> 2(coat colour) black back and pinna hairs and agouti belly and flanks. Homozygotes die prenatally.Order
a<l> 2
C3H101H-a<17H>/H a<17H> UN(hair - colour) non-agouti-17-Harwell.Order
C3H101H-a<18H>/H a<18H> 2Homozygotes are non-agouti with very dark pinna hairs. A/a<18H> looks wild-type. a/a<18H> look umbrous i.e. non-agouti with agouti hairs along side of body and on the belly. Order From EMMA
C3H101H-a<19H>/H a<19H> UN(hair - colour) non-agouti-19-Harwell, black pinna hairs.Order
C3H101H-a<20H>/H a<20H> UN(hair - colour) non-agouti-20-Harwell.Order
C3H101H-a<da>/H a<da> 2(hair - colour) Non-agouti with dark agouti belly.Order
C3H101H-a<t-2H>/H a<t-2H> 2(hair - colour) black and tan.Order
C3H101H-a<tl>/H a<tl> UNResembles a<t> but there is no clear dividing line between black on the back and tan on the belly. Additionally, the tan colour is present on face spreading above the eyes.Order
C3H101H-a<u>/H a<u> 2(hair - colour) agouti-umbrous.Order
STOCK A<y>/H A<y> 2(hair - colour, eye - colour, size - obesity, sterile) heterozygotes all the hair pigment is yellow and the eyes are black; they usually become obese and sterile after the first few months.Order
B6.Cg-Tg(ACTFLPe)920
5Dym/H
Tg(ACTFLPe)9205Dym UNNo overt phenotype. Order From EMMA
C3H101H-Ada<b>/H Ada<b> UNOrder
C3H101H-Ada<c>/H Ada<c> UNOrder
Ada<a> UN
B6;129P2-Adamts1<tm1
Dgen>/H
Adamts1 16No overt phenotype.Order From EMMA
B6;129P2-Adamts2<tm1
Dgen>/H
Adamts2 11No overt phenotype.Order From EMMA
B6;129P2-Adcyap1r1<t
m1Dgen>/H
Adcyap1r1 6No visible phenotype.Order From EMMA
129P2/OlaHsd-Fbxl3<G
t(CB0226)Wtsi>/H
Fbxl3 14Order
C3H.Cg-Fbxl3<Afh>/H Fbxl3<Afh> 14Identified in circadian rhythm screen. Mutants have a long circadian period 24.23hr (a) and 24.12hr (b).Order From EMMA
Akt2<tm1Wtsi> Akt2 7None.Order
Tg(DSPMKP3)Ox(Albert
)
Order
Ananisi An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. Order From EMMA
Anaya An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. Order From EMMA
Andromeda An ENU-induced mutation causing heritable anti-nuclear antibodies with variable penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry. Order From EMMA
TgN(DSPMKP3)Ox(Angel
a)
Order
Ann Boleyn Anb UNHeterozygotes have polydactyly of the hind limbs. Homozygotes have polydactyly of all four limbs.Order
TgN(DSPMKP3)Ox(Annek
a)
Order
Antonia An ENU-induced mutation causing heritable anti-nuclear antibodies and variable proliferative and membranous glomerulonephritis with partial dominant phenotype and penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry and immunoglobulin levels.Order From EMMA
C57BL/6J-Apc<Min>/5H Apc<Min> 18Mice develop life-shortening intestinal polyposis.Order From EMMA
C57BL/6J-Apc<Min>/2H Apc<Min> 18(adenoma - anaemia) multiple intestinal neoplasia.Order From EMMA
ApoE/PAI-1 Apoe<tm1Bres> 7Shortened life span.Order From EMMA
ApoE/PLGN Apoe<tm1Bres> 7Rectal prolapse. Shortened life span in homozygotes.Order From EMMA
apoE tPA Apoe<tm1Bres> 7None. Order From EMMA
Plat<tm1Mlg> 8
apoE tTg Apoe<tm1Bres> 7None.Order From EMMA
Tgm2<tm1Gml> 2
STOCK Ar<Tfm>/H Ar<Tfm> XHemizygous males are outwardly female in appearance but internally they have testes.Order
Araf<tm1Mmc> Araf<tm1Mmc> XAraf knockout mice litters are approximately one-third to half the size of their wildtype siblings from day 3 to pre weaning and so do not normally reach breeding age. However, placing them on supplementary diet or removing competition from other siblings, allows some to survive post weaning. Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-raf protein Kinase gene.Order
Araf<tm1Mmc> Araf<tm1Mmc> XX-linked gene.Order
Araf:Beta-geo Order
Araf<tm1Mmc> Araf<tm1Mmc> XAraf knockout mice litters are approximately one-third to half the size of their wildtype siblings from day 3 to pre weaning and so do not normally reach breeding age. However, placing them on supplementary diet or removing competition from other siblings, allows some to survive post weaning. Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-raf protein Kinase gene.Order
B6;129S4-Rhog<tm1Tnr
>/H
Rhog<tm1Tnr> 7Mild hyper reactivity of lymphocytes to antigen receptor engagement.Order From EMMA
Ariel Hind limb paralysis from day 12 in homozygotes.Order
C3H101H-Atp7a<Mo-10H
>/H
Atp7a<Mo-10H> X(hair - colour) mottled.Order
C3H101H-Atp7a<Mo-11H
>/H
Atp7a<Mo-11H> X(hair - colour) mottled.Order
C3H101H-Atp7a<Mo-12H
>/H
Atp7a<Mo-12H> X(hair - colour) mottled.Order
C3H101H-Atp7a<Mo-13H
>/H
Atp7a<Mo-13H> X(hair - colour) mottled.Order
C3H101H-Atp7a<Mo-14H
>/H
Atp7a<Mo-14H> X(hair - colour) mottled. Males do not survive.Order
C3H101H-Atp7a<Mo-17H
>/H
Atp7a<Mo-17H> X(hair - colour) mottled.Order
Atp7a<Mo-18H> Atp7a<Mo-18H> UNMottled coat. Hemizygous males die in utero. The coat colour of females are typical Atp7a<Mo> but Atp7a<Mo-18H> has not been studied in depth.Order
C3H101H-Atp7a<Mo-blo
>/H
Atp7a<Mo-blo> X(hair colour) blotchy.Order
C3H101H-Atp7a<Mo-ca>
/H
Atp7a<Mo-ca> X(hair colour) Mottled candy.Order
C3H101H-Atp7a<Mo-dp>
/H
Atp7a<Mo-dp> X(hair - colour, gait, skeleton) mottled dappled.Order
C3H101H-Atp7a<Mo-spt
>/H
Atp7a<Mo-spot> X(hair - colour) mottled spot.Order
C3H101H-Atp7a<Mo-to>
/H
Atp7a<Mo-to> X(hair - colour) mottled tortoiseshell.Order
C3H101H-Atp7a<Mo-vbr
>/H
Atp7a<Mo-vbr> X(hair - colour, viable brindled.Order
C3H;C-Pde6b<atrd1>/H Pde6b<atrd1> 5Eyes-slow onset retinal degeneration.Order From EMMA
C3H;C-Pde6b<atrd2>/H Pde6b<atrd2> 5Slow onset retinal degeneration.Order From EMMA
C3H;C-Pde6b<atrd3>/H Pde6b<atrd3> 5Eyes- slow onset retinal degeneration.Order From EMMA
C3H;C-Pde6b<rd1-2H>/
H
Pde6b<rd1-2H> 5Slow onset retinal degeneration.Order From EMMA
C3H;C-Pde6b<rd1-3H>/
H
Pde6b<rd1-3H> 5Slow onset retinal degeneration.Order From EMMA
C3H;C-Pde6b<rd1-4H>/
H
Pde6b<rd1-4H> 5Slow onset retinal degeneration.Order From EMMA
B(Beta)DB<tm2Ked> Dtnb 12None observed. Order
B10.L-Lsh Slc11a1<r> 1Order
B10ScSn.BXSB-(D1Mit3
-D1Mit320) Chr Y<BXSB/MpJ>/BjmjrH
Enhanced autoantibody spectrum and titre.Order From EMMA
B10ScSn.BXSB-(D1Mit3
-D1Mit235) Chr Y<BXSB/MpJ>/BjmjrH
Enhanced autoantibody spectrum and titre. Order From EMMA
B10ScSn.BXSB-(D1Mit1
23-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH
Enhanced autoantibody spectrum and titre. Glomerulonephritis susceptibility.Order From EMMA
B10ScSn.BXSB-(D1Mit2
35-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH
Glomerulonephritis susceptibility.Order From EMMA
B10ScSn.BXSB-(D1Mit3
03-D1Mit305) Chr Y<BXSB/MpJ>/BjmjrH
Glomerulonephritis susceptibility.Order From EMMA
B10ScSn.BXSB-(D1Mit3
3-D1Mit223) Chr Y<BXSB/MpJ>/BjmjrH
ANA, 75% mortality, enhanced autoantibody titre, severe glomerulonephritis.Order From EMMA
B6J.CBA-TgN(HDexon1)
61Gpb
Tg(HDexon1)61Gpb UNHuntington's disease, tremors, weight loss, movement disorders, died on average at 7 months old.Order
B6.129-Igf1r<tm1.2Mh
z>/Orl
Igf1r<tm1.2Mhz> 7Live longer; resistant to oxidative stress.Order
B6.Cg-Mir155<tm1.1Br
d>Tyr<c-Brd>/H
Mir155<tm1.1Brd> 16No visible phenotype is associated with this mutation but the mice do exhibit reduced lung airway remodelling & deficient B-cell, T-cell & dendritic cell function. This mutation is on a C57BL/6<c-/c-> background and is albino in appearance. The BIC mice (EMMA ID EM:02231) have been backcrossed at least 5 times to C57BL/6, thus making them suitable for bone marrow transplantation, without rejection, to any C57BL/6 mice, regardless of coat color.Order From EMMA
Tyr<c-Brd> 7
B6;D2-Tg(Sycp1-cre)4
Min/J
Tg(Sycp1-cre)4Min UNNone given.Order
B6CBA-Tg(HDexon1)61G
pb
Tg(HDexon1)61Gpb UNModel for Huntington's disease, tremors, weight loss, movement disorders, die on average at 7 months old.Order
BAC3 Normal.Order
BALB/c Albino.Order
BALB/cOla White coat colour.Order
C.Cg-Il1rn<tm1Nick>/
Nick
Il1rn<tm1Nick> 2Strain sporadically and independently develops rheumatoid-like arthritis, localised psoriasis-like lesions and patchy transmural destructive arteritis of the elastic vessels. Hygiene dependent (negative correlation). Different strain dependence of each disease. This strain, our SPF lab, 80% affected (each disease independently) at 200 days.Order From EMMA
CBy.129-Rag2<tm1Fwa>
/H
Rag2<tm1Fwa> 2Chronic intestinal inflammation, colitis.Order From EMMA
CBy.129-Cd44<tm1Ugu>
Rag2<tm1Fwa>/H
Cd44<tm1Ugu> 2Chronic intestinal inflammation, colitis.Order From EMMA
Rag2<tm1Fwa> 2
CBy.129-Cd44<tm2.1Ug
u> Rag2<tm1Fwa>/H
Rag2<tm1Fwa> 2Mice are homozygous for both Rag-/- and CD44v10-/- knockouts. Rag2-/-, no mature T and B cells. CD44v10-/-, strongly reduced symptoms in autoimmune diseases. Used in mouse models of experimental colitis.Order From EMMA
Cd44 2
CBy.129-Cd44<tm1.1Ug
u> Rag2<tm1Fwa>/H
Cd44<tm1.1Ugu> 2Rag2-/-: no mature T and B cells. CD44v6v7-/-: strongly reduced symptoms in autoimmune diseases.Order From EMMA
Rag2<tm1Fwa> 2
BALB/cPye Order
C3H101H A/A<w>-Bbn/H Bbn UNAffected animals are deaf and exhibit headbobbing and circling behaviour.Order From EMMA
C3H101H-Bhd/H Bhd X(head - nose) broad-headed.Order
BHV11 Abnormal craniofacial features.Order From EMMA
BHV26 The alternation score suggest this line has a potential short term working memory deficit. Order From EMMA
BHV31 High anxiety.Order From EMMA
BHV32 Hyperactivity.Order From EMMA
BHV43 Possible short-term working memory deficit indicated by reduced spontaneous alternation in the Y-maze. Order From EMMA
BHV48 Rgs18 1None apparent, in heterozygotes.Order From EMMA
C3H.Cg-Trpc3<Mwk>/H Trpc3<Mwk> 3Staggering, ataxic with limited movement in back legs. Heterozygotes are usually small.Order From EMMA
ABL Inbred strain.Order
C3H101H-Fras1<bl>/H Fras1<bl> 5(eye, feet, kidney, skin) blebbed.Order From EMMA
C57BL/6J-blst/H blst UNSpontaneous recessesive coat colour mutation - light grey coat colour. Order From EMMA
C57BL/6J-Btnt/H Btnt UNTan coat colour on belly.Order From EMMA
C3H;C-Snap25<Bdr>/H Snap25<Bdr> 2Poor sight. Blind drunk. Small at weaning. SHIRPA anomalies including reduced or absent visual placing and staggering gait. Homozygotes have not been identified.Order From EMMA
C57BL/6J-Blite/H Blite UNWhite with non-agouti patches. Some patches reverting to non-agouti are visible in a small number of offspring. Timed matings of heterozygous stock can yield oedematous embryos.Order From EMMA
BLUFF Fluffy coat, abnormal hair distribution and texture. Order
C3H101H-Papss2<bm>/H Papss2<bm> 19(skeleton) dwarfism - cleft palate brachymorphic.Order
BMD2 Low bone mineral density.Order
Bmp5<se-19H> Bmp5<se-19H> UNShort-ear.Order
Bmp5<se-20H> Bmp5<se-20H> UNShort-ear.Order
Bmp6<tm1Rob> Bmp6<tm1Rob> 13Mice show no overt phenotype.Order From EMMA
Bmp7<tm2Rob> Bmp7<tm2Rob> 2Homozygous embryonic lethal.Order From EMMA
Bmp7<tm1Rob> Bmp7<tm1Rob> 2This strain is a null allele of BMP7 generated by replacing the BMP7 coding sequence by a neomycin cassette. BMP7 is required in the metanephric mesenchyme of the developing kidney to support maintenance of this cell population during organogenesis. Homozygous lethal at birth due to kidney agenesis. Order From EMMA
Zic3<Bn>, Atp7a<Mo-b
r>
Zic3<Bn> X(coat colour) mottled brindled, Bent tail.Order
C3H101H-Nsdhl<Bpa-1H
>
Nsdhl<Bpa-1H> X(skin, size, tail ) bare patches.Order
C3H101H-Nsdhl<Bpa-3H
>
Nsdhl<Bpa-3H> X(skin - skeleton) scarring on females at 4 days old. More females than males born and some have spine abnormalities. Bare patches are clearly visible at weaning.Order
C3H101H-Nsdhl<Bpa-4H
>
Nsdhl<Bpa-4H> X(skin - skeleton) phenotype classed at 8 days but are barely visible at weaning. More females than males are born and they are prone to spinal abnormalities.Order
C3H101H-Nsdhl<Bpa-5H
>
Nsdhl<Bpa-5H> X(skin - skeleton - size) phenotype classed at 8 days some are small at birth. More females than males born and they are prone to spinal abnormalities.Order
C3H101H-Nsdhl<Bpa-6H
>
Nsdhl<Bpa-6H> X(skin) bare patches classed at 4 days and are clearly visible at weaning.Order
C3H101H-Nsdhl<Bpa8H>
/H
Nsdhl<Bpa-8H> XMale lethal. Females are classified at 8 days by scarring on the skin, small at weaning. The adult females are striped.Order From EMMA
C3H101H-Br/H Br 17(nose - mouth, kidneys - size) brachyrrine.Order
Brd7<tm1aWtsi> Brd7 8None.Order From EMMA
Brn3a Knockout Pou4f1 14Homozygote neonate lethality caused by lack of suckling due to defects in sensory and motor neurons.Order
Brn3b Knockout Pou4f2 8Homozygotes are blind due to failure of the retinal ganglia to develop.Order
B6NDen;B6N-Brpf1<tm1
a(EUCOMM)Wtsi>/H
Brpf1<tm1a(EUCOMM)Wt
si>
6 Order From EMMA
C3H101H-Gsdma3<Bsk>/
H
Gsdma3<Bsk> 11(skin, eyes) bareskin, corneal opacities.Order
Bstk (hair - colour) Affected individuals have a belly spot and light feet.Order
bv bv 5Bronx Waltzer. Recessive mutant; hyperactivity, circling, headbobbing and deafness in the homozygote.Order From EMMA
bv (Bronx Waltzer) bv 5Bronx Waltzer.Order From EMMA
C.D2-vil6 Order
C3H-nr/H nr 8Homozygotes are smaller in size and have hyperactive ataxic behaviour.Order
C3H/HeH Order
C3H;C-Chd7<Todo>/H Chd7<Todo> 4Headweaving and circling in heterozygotes. Homozygotes die at mid gestation with vascular and brain defects.Order From EMMA
C3H;C-Chd7<Edy>/H Chd7<Edy> 4Headweaving/circling.Order From EMMA
C3H;C-Chd7<Dz>/H Chd7<Dz> 4Dizzy. Heterozygote animals are small at birth with slight kink in tail and exhibit head weaving and circling behaviour. Order From EMMA
B6.Cg-Il1rn<tm1Nick>
/Nick
Il1rn<tm1Nick> 2Strain resistant to arthritis, arteritis and psoriasis (seen in BALB/c) but highly susceptible to undefined 'malaise' under conventional conditions. Order From EMMA
B6.129P2-Fgfr3<tm1.1
Aomw>/Aomw
Fgfr3<tm1.1Aomw> 5All homozygous males, some homozygous females and some heterozygous males develop an abnormal skull phenotype sometimes with malocclusion, and may be smaller in size. The phenotype is not fully penetrant.Order From EMMA
C57BL/6-Lep<ob>/H Lep<ob> 6Order
B6CBF1-Tg(ATXN3*)84.
2Cce/H
Tg(ATXN3*)84.2Cce UNSlowly progressive cerebellar defecit from 4weeks of age; wide flattened gait, clasping of all 4 limbs, neuronal loss, gliosis & neuronal intranuclear inclusions present in the pons & cerebellum, peripheral nerve demyelination.Order From EMMA
C57BL/6Apb-Ptprc<loc
>/Apb
Ptprc<loc> 1Decreased expression of CD45 on CD19+ B cells etc.Order From EMMA
C57BL/6Apb-Zap70<mur
>/Apb
Zap70<mur> 1Reduced naïve CD4+ and CD8+ T cells which are hyperactivated, reduced CD4+ cells, defect in TCR signal transduction, impaired but not severe response to anti-TCR stimulation, T cell intrinsic defect, elevated serum levels of IgG2b.Order From EMMA
C57BL/6J-A<vy>/H A<vy> 2Order
C57BL/6J-Krt25<Re>/H Krt25<Re> 11Order
C57BL/6J-Kitl<Sl-d>/
H
Kitl<Sl-d> 10Order
C57BL/6J-Ucp1<m1H>/H Ucp1<m1H> 8Homozygotes are unable to thermoregulate.Order
STOCK a<t>/H a<t> 2(hair - colour) the back is black and the belly cream or yellow.Order
C57BL/Ola-Gpi1-s<c>,
c/Ws
Gpi1<c> 7Order From EMMA
B6.AK-Gpi1<a>/Ws Gpi1<a> 7Order From EMMA
C57bl/ws-TgN(Hbb-b1)
83Clo/ws
Tg(Hbb-b1)83Clo UNNone expressed. Order From EMMA
C57BR/cd Hepatomas in 25% of males.Order
C3H101H-Krt71<Ca-2H>
/H
Ca<2H> UN(Coat - texture) caracul. Homozygotes are indistinguishable from heterozygotes. Both are fully fertile and viable. Vibrissae are curved, and hair is wavy from time of first appearance until about 4 weeks of age. After this time the waves disappear, but the hair has a plush-like look.Order
Krt71<Ca-d>, Scn8a<m
ed>
Scn8a<med> 15(Coat - texture, motor end plate).Order
Krt71<Ca-d> 15
129P2/OlaHsd-Tpcn1<G
t(XG716)Byg>/H
Tpcn1 5Order
B6;129-Capn5<tm1Nde>
/H
Capn5<tm1Nde> 7None apparent.Order From EMMA
TgN(UbiCFL)Ox(Calvin
)
Order
Candy Hyperglycaemia, glycosuria. Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. Order From EMMA
Candy2 Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. Order From EMMA
Candy3 Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age.Order From EMMA
Candy4 Elevated plasma glucose at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age. Order From EMMA
Candy5 Elevated plasma glucose and phosphate at 16 weeks of age. Glucose also detected in the urine at 24 weeks of age.Order From EMMA
B6;129P2-Capn1<tm1Dg
en>/H
Capn1 19No overt phenotype Order From EMMA
C3H.C-Casp3<I216F>/H Casp3 8Reduced apoptosis in homozygotes. Phenocopies Caspase 3 null alleles.Order From EMMA
C3H-Cat2/H Cat2 1(eye - cataract) cataract-2 dominant cataract.Order
C3H101H-Cryga<tol>/H Cryga<tol> 1Dominant cataract.Order
C3H-Cat5<To2>/H Cat5<To2> 10(eye - cataract) cataract-5 dominant cataract.Order
CBA-TgN(IL5) 1 GlX Transgenic pups have high leucocyte counts and are readily identifiable by differential leucocyte counts.Order From EMMA
CBA/CaH Xic<a> XOrder
Runx1t1<tm1Fc> Runx1t1<tm1Fc> 4Order
CCBAN3-2371 Order
CCBAN4-2513 Order
CCBAN4-2547 Order
B6;129P2-Ccr9<tm1Dge
n>/H
Ccr9 9None.Order From EMMA
CD2/NPM-ALK Mice develop tumours of haemopoietic organs within 2 years of age in approx. 10% of mice.Order From EMMA
CD45R03 Under investigation: not severely immunocompromised.Order
CD45RABC3 Under investigation, not severely immunocompromised; no obvious immunological dysfunction.Order
CD45RB2 Under investigation: not severely immunocompromised.Order
CD45RO-C817S Severe defects in B and T cell differentiation and function.Order
CD45RO9 Under investigation, not severely immunocompromised.Order
CEMO_S2 Order
CEMO_S3 Order
CEMO_S5 Order
CHANGELING Motor co-ordination problems & death before weaning age.Order
TgN(UbiCFL)Ox(Chelse
a)
Order
Chm Tyr<c-ch> 7Order
STOCK Oca2<p>Tyr<c-c
h>Myo7a<sh1>Prss8<fr>/H
Oca2<p> 7Order
Prss8<fr> 7
Tyr<c-ch> 7
Myo7a<sh1> 7
C3H101H-Flt4<Chy>/H Flt4<Chy> 11Milky abdomen shortly after birth. (abdomen, feet) chylous ascites.Order From EMMA
Chy-Ma like (abdomen, feet) chylous ascites. Milky abdomen. Small at birth and weaning. May have low fertility. Some may have coat dilution or headbobbing.Order
C3H101H-Chy2/H (abdomen, feet , tail). Typical chylous phenotype of puffy feet, swollen tail. No knowledge of fate of homozygote. Order
Chy5 Chy5<Ma1> UNmilky abdomen.Order
Chy6 Chy6<Ma2> UNmilky abdomen.Order
C3H101H-Chy7/H (abdomen, feet) chylous ascites. Milky abdomen.Order
CIRCA12 Identified in circadian rhythm screen. Has a reduced period lengthening response when subjected to constant light conditions.Order
CIRCA2 Long activity under constant dark period.Order
CIRCAD21 Order
B6.Cg-Cited2<L247P>/
H
Cited2 10Although the amino acid change occurs in a highly conserved residue. The mutant is homozygous viable and fertile, with no detectable phenotype. In trans to the Knock-out allele, it is viable and phenotypically normal. Order From EMMA
B6J.129-Cited2<tm2Bh
a>/H
Cited2<tm2Bha> 10Cre-mediated recombination throughout the entire epiblast of early embryos recapitulates the complete loss of function phenotype of Cited2, which include cardiac malformations, adrenal agenesis, fusion of cranial ganglia, abnormal cardiac neural crest migration, excencephaly and left right patterning defects.Order From EMMA
TgN(UbiCFL)Ox(Cleo) Order
CMV Gal4 None.Order
STOCK Tg(Col2a1-cre)
1Bhr/H
Tg(Col2a1-cre)1Bhr UNNo overt phenotype.Order From EMMA
C3H101H-Col4a1<Bru>/
H
Col4a1<Bru> 8(eyes - cataract - size, skin - colour) bruised.Order From EMMA
STOCK Col4a1<Raw>/H Col4a1<Raw> 8Retinal ateriolar wiring. Shiny retinal blood vessels.Order From EMMA
STOCK Col4a1<Svc>/H Col4a1<Svc> 8Small with vacuolar cataract. Also other eye abnormalities. Mutants are small and bruised at birth and tend to remain small throughout life. Variable eye findings, the most consistent of which is a vacuolar cataract. Other eye findings include enlarged eyes, corneal opacity, iris-corneal adhesions, iris-lens adhesions, retinal vascular abnormalities.Order From EMMA
CON Kitl<Sl-con> 10(coat - colour) steel. Darkly pigmented genitalia and slightly lighter coat in heterozygote. Homozygotes are grey with dark genitalia.Order
Edar<dl> 10
Connexin26-Knockout
(C3H)
Gjb2 14Heterozygotes appear wildtype and can hear, homozygous embryonic lethal.Order
C3H;C-Gjb2<E119stop>
/H
Gjb2<E119stop> 14Homozygous lethal, heterozygotes appear as wildtypes.Order
Connexin26<Har1> Wil
d type
Homozygous lethal, heterozygotes appear as wildtypes.Order
TgN(UbiCFL)Ox(Conrad
)
Order
Cookson Mouse Eng 2Order
Cordon Bleu Cobl 11None.Order
STOCK Scrib<Crc>/H Scrib<Crc> 15Neural tube defects.Order
C3H.Cg-Scrib<Crc>/H Scrib<Crc> 15Order
C3H101H-Crm/H Crm X(coat - colour) cream.Order
Cry1<tm1Jhjh> Cry1<tm1Jhjh> 10Order
129-Ctsg<tm1.1Roes>/
H
Ctsg<tm1.1Roes> 14Mice deficient in Ctsg are susceptible to fungal infections, despite normal neutrophil development and recruitment. Order From EMMA
CVBA 3'/Utrophin+/-/
mdx
CVBA 3'/Utrophin+/-/mdx mice are transgenic for the dystrophin cDNA with a deletion of exons 17-48 under the control of the MCK promoter.Order From EMMA
C3H;C-Gjb2<I128V>/H Gjb2<I128V> 14Heterozygotes appear wildtype and show normal hearing.Order From EMMA
C3H;C-Chd7<Cycn>/H Chd7<Cycn> 4Headbobbing/circling. Heterozygotes exhibit headweaving and circling behaviour. Homozygous foetuses exhibit midgestational lethality potentially due to vascular and/or anterior neural tube defects.Order From EMMA
D1ApA63(Knockin) Order
C3H;C-Dfp2/H Dfp2 4Heterozygotes have dark pigmentation on footpads and additional areas such as tail, ears etc.Order From EMMA
DBA/2 Non-agouti brown, pink eyes. Susceptible to audiogenic seizures. Spontaneous calcified heart lesions progress with age. Order
C3H101H-Dbf/H Dbf 1Many extra toes on all feet. Homozygote lethal. Dominant, digits - number, limbs - bones, size - small, reduced viability, skull, sterility, cerebrospinal fluid??Order From EMMA
C3H101H-Dct<slt>/H Dct<slt> 14Slatey.Order
DDK Order
C3H101H-Del(1)55H (size - birth - weaning) small at birth and weaning.Order
C3H101H-Del(1)57H (size - birth, anaemia) Small at birth and seemingly anaemic.Order
C3H101H-Del(1)58H (size - birth - weaning, hair - colour) small at birth and at weaning with dark coats.Order
C3H101H-Del(1)66H (size - birth - weaning, hair - colour) heterozygote milky abdomen at birth, small at weaning.Order
C3H101H-Del(1)70H (size - birth - weaning, head) small at birth and weaning sometimes with a domed head.Order
C3H101H-Del(1)6H (size - birth - weaning, head) small at birth and weaning, with domed head.Order
C3H101H-Del(1)42H (size - birth - weaning - eyes) small at birth with eyes open and small at weaning with small eyes.Order
C3H101H-Del(1)33H (size - birth - weaning, head) small at birth and weaning, with a slightly domed head.Order
C3H101H-Del(1)27H/H (size - birth weaning, hair - colour) small at birth and weaning, some have white feet. No information available about homozygotes.Order
C3H101H-Del(10)69H (size - birth - weaning, head) heterozygotes small at birth and weaning, with domed head.Order
Del(10)Mgf<Sl-28H>41
H
Kitl<Sl-28H> UNsteel.Order
C3H101H-Del(12)75H (size - birth weaning, hair - colour, behaviour) small at birth and small at weaning with head bobbing and dark coat.Order
C3H101H-Del(13)52H (size - birth - weaning, hair - colour) small at birth and weaning, sometimes with dark coats.Order
C3H101H-Del(13)80H Del(13)80H carriers are small, with small eyes and domed heads. Del(13)80H +/+ sa has the satin phenotype.Order From EMMA
C3H101H-Del(13)36H Order
Del(14)Ednrb<s-163H>
10H
Ednrb<s-163H> UNOrder
Del(14)Ednrb<s-163H>
10H
UN
Del(14)Ednrb<s-174H>
15H
Ednrb<s-174H> UNOrder
DelEdnrb<s-174H>15H UN
Del(14)Ednrb<s-175H>
14H
Ednrb<s-175H> UNOrder
DelEdnrb<s-175H>14H UN
Del(14)Ednrb<s-175H>
14H
UN
Del(14)Ednrb<s-179H>
23H
DelEdnrb<s-179H>23H UNOrder
Ednrb<s-179H> UN
Del(14)Ednrb<s-180H>
28H
DelEdnrb<s-180H>28H UNSmall at birth and weaning.Order
Ednrb<s-180H> UN
Del(14)Ednrb<s-181H>
31H
DelEdnrb<s-181H>31H UNOrder
Ednrb<s-181H> UN
Del(14)Ednrb<s-182H>
32H
Ednrb<s-182H> UNOrder
DelEdnrb<s-182H>32H UN
Del(14)Ednrb<s-184H>
29H
Dct<slt> UNOrder
DelEdnrb<s-184H>29H UN
Ednrb<s-184H> UN
Del(14)Ednrb<s-187H>
39H
DelEdnrb<s-187H>39H UN(size) small with high expression.Order
Ednrb<s-187H> UN
Del(14)Ednrb<s-198H>
60H
DelEdnrb<s-198H>60H UNOrder
Ednrb<s-198H> UN
C3H101H-Del(16)51H (size - birth - weaning, hair - colour) small at birth and weaning, some white feet.Order
C3H101H-Del(18)20H (size - weaining, hair - colour, tail, cleft palate) small at weaning, sometimes white feet, variable tail abnormalities, tail kinks to tight curling of tail, some cleft palates/lips seen in heterozygotes also exencephaly.Order
C3H101H-Del(2)59H (size - birth - weaning, genetalia - colour, head) small at birth and small at weaning with small eyes and domed/short heads and some have dark genitalia.Order
Del(2)Sey<2H>82H Pax6<Sey-2H> 2Small at birth and weaning. Small or closed eyes, white feet.Order
C3H101H-Del(2)Sey<4H
>83H/H
Pax6<Sey-4H> UNSmall eyes and sometimes small at birth.Order
Del(2)Sey<4H>83H UN
C3H101H-Del(2)35H (size - birth - weaning, hair - colour) small at birth and weaning, sometimes white feet, occasional belly spot.Order
STOCK Del(3)48H Small.Order
C3H101H-Del(3)64H (size - birth - weaning, head) small at birth and weaning, unusual shaped heads.Order
C3H101H-Del(4)17H (size - birth - weaning, behaviour - waltzing, skin - colour) small at birth and weaning, waltzer type behaviour, variable white feet.Order
C3H101H-Del(5)68H (size - birth weaning, behaviour) small at birth and weaning with erratic behaviour.Order
Del(5)Kit<W-34H>43H Kit<W-34H> UNOrder
DelKit<W-34H>43H UN
Del(5)Kit<W-35H>47H DelKit<W-35H>47H UNOrder
Kit<W-35H> UN
Del(5)Ph<2H>25H Ph<2H> UNpatch.Order
C3H101H-Del(6)26H (size - birth weaning, hair - colour) small at birth and weaning with dark (umbrous) coat.Order
C3H101H-Del(7)49H (size - birth - weaning, hair - colour) small at birth and weaning, dark coats, white toes. Phenotype and deletion may not be associated.Order
C3H101H-Del(7)56H (size - birth - weaning, hair - colour) small at weaning, some have milky abdomens.Order
C3H101H-Del(8)50H (size - birth - weaning, hair - colour) small at birth and weaning, with dark coats.Order
C3H101H-Del(8)62H (size, head, behaviour - circling) small, some with short heads, circling.Order
C3H101H-Del(8)72H (size - birth weaning, hair - colour, behaviour) small at birth and weaning, also dark coats. Some show circling behaviour.Order
C3H101H-Del(8)7H (abdomen, feet) chylous ascites.Order
C3H101H-Del(8)74H (feet, tail) milky abdomen, puffy feet and thick tail.Order
C3H101H-Del(9)4H (size - small, white spotting) low grade white head/feet tail spotting, carriers small from birth.Order
129P2/OlaHsd-Tpcn2<G
t(YHD437)Byg>/H
Tpcn2<Gt(YHD437)Byg> 7Order
C57BL/6J-H19<tm2Wrk> H19<tm2Wrk> 7Deletion of the H19 transcription start site shows no effect on imprinting expression or DNA methylation. Order From EMMA
C3H101H-Dh/H Dh 1dominant hemimelia, Classified at birth by absence of spleen. Toes not always abnormal. Het.show preaxial polydactyly or oligodactyly of the hind limbs, tibial hemimelia, & sometimes reduction of the femur & pubic element of the pelvic girdle, no. etc...Order
C3H;C-Dilp3/H Dilp3 UNDilated pupils.Order From EMMA
C3H;C-Dilp4/H Dilp4 UNMice carrying this mutation have permanently dilated pupils.Order From EMMA
C3H101H-Dkf/H (feet - colour, tail - colour, size - weaning) Darkfoot, dominant, homozygous lethal. Heterozygotes have dark foot-pads and tails, also slightly small at weaning.Order
Dl<Slk2H> Edar<Dl-Slk2H> UNGreasy coat, hairy tail.Order
C3H101H-Edar<Dl-slk>
/H
Edar<Dl-slk> 10(hair, teeth) sleek.Order
STOCK Tmc1<dn> Tmc1<dn> 19Deafness.Order From EMMA
C3H101H-Dp(1)6H Small at birth and weaning.Order
C3H101H-Dp(12)7H joined toes on hind feet.Order
C3H101H-Dp(12)9H dark coat and skin seen on ears, feet and tail with occasional domed head.Order
C3H101H-Dp(13)17H Small at birth and weaning.Order
C3H101H-Dp(14)18H small at birth and weaning, some have dark coats.Order
C3H101H-Dp(14)2H dark coat, small, white toes/feet.Order
C3H101H-Dp(15)5H Slightly small at weaning, some show erratic waltzing type behaviour, variable white feet/tail, dark coats.Order
C3H101H-Dp(16)15H Small at birth and weaning, sticky eyes, domed head.Order
C3H101H-Dp(16)8H Order
C3H101H-Dp(18)4H Small with dark coats.Order
C3H101H-Dp(2)11H (size - birth - weaning, hair - colour, behaviour) small at birth and small at weaning with dark coat and showing abnormal behavior. i.e. shaking, head bobbing and very active.Order
C3H101H-Dp(3)10H (size, head) heterozygotes are usually small with a domed head.Order
C3H101H-Dp(4)20H Small at weaning with a short domed head. Homozygous lethality. some dark coat and low grade white spotting on the feet only was seen.Order
C3H101H-Dp(7)1H Small at weaning, dark coats (some).Order
C3H101H-Dp(7)16H small at birth and small at weaning with dark coats.Order
C3H101H-Dp(7)19H Small at birth and weaning.Order
C3H101H-Dp(9)12H Small with dark coat.Order
C3H101H-Dp(9)14H Small at birth and weaning, some have dark coats, short heads and twisted jaws.Order
C3H101H-Dp(9)3H Heterozygotes small at birth and weaning, some fused toes, pointed faces.Order
STOCK Lmx1a<dr-J> Lmx1a<dr-J> 1Deafness, circling behaviour and hyperactivity in homozygotes. They have neuronal migration disorders in the cerebral cortex, cerebellum and hippocampus. White belly spots, short tails and abnormalities of the fallopian tubes (dr<2J> only)are seen in some.Order
C3H101H-Mc1r<E-tob>/
H
Mc1r<E-tob> 8Order
ecd Cartilage type defect.Order
Ednrb<s-136H> Ednrb<s-136H> UNLess spotting than Ednrb<s>.Order
C3H101H-Ednrb<s-162H
>/H
Ednrb<162H> UNOrder
C57BL-Eh/H Eh 15Hairy ears (Eh). Reduced pinna with tufts of hair on inner surface. Homozygous lethal. Breeding poor when crossed to C57BL/6J. Order
ELK6K<-/->(lambda)<-
/->
Production of rat kappa light chains on mouse lambda and kappa light chain knockout background.(or on mouse kappa-type light chain knockout only, with mouse lambda-type light chain being wild type instead of knockout.Order
B6;129P2-Eltd<tm1Dge
n>/H
Eltd1 3None.Order From EMMA
Epc1<tm1aWtsi> Epc1 18None.Order From EMMA
C3H101H-Es3<c-nH> Es3<c-nH> 11Order
Es3<c> UN
Es3<b> UN
B6;129P2-Esr2<tm1Dge
n>/H
Esr2 12No visible phenotype.Order From EMMA
129S9/SvEvH-Evta/H Evta UNWhite coat with non-agouti specking and occasional non-agouti patches.Order From EMMA
B6NDen;B6N-Slc38a10<
tm2a(EUCOMM)Wtsi>/H
Slc38a10<tm2a(EUCOMM
)Wtsi>
11Order From EMMA
TgN(FLU)Ox(Fergie) Order
C3H;C-Fer/H Fers 4Heterozygotes have abnormal hind limbs, vigourous touch escape and circling. Order From EMMA
TgN(FLU)Ox(Fiona) Order
FMLC-TM/12 Statistically elevated levels of leptin & adiponectin after overnight fasted bleeds at 12wks of age with increased bodyweight. Bodyweight & adiponectin levels still elevated after an overnight fasted bleed at 16wks of age. After DEXA analysis: statistically increased bodyweight, fat mass & % body fat.Order
C3H101H-Fnld/H Fnld XFaint lined.Order
C3H;C-Gsdma3<Fgn>/H Gsdma3<Fgn> 11Mice carrying this mutation show progressive hair loss. Weanlings show a typical ragged coat phenotype. Following this mice go through several cycles of hair loss and regrowth. Adult mice eventually become almost hairless with a small amount of hair around the snout. Order From EMMA
FNOS2 Circling, vestibular defects. Heterozygotes can be identified by mild head bobbing or circling behaviour. Mice with this behaviour usually show morphological changes in the inner ear. Order From EMMA
Foxh1<tm1Jlw> Foxh1<tm1Jlw> 15Homozygous lethal at day 8 of gestation.Order From EMMA
C3H-Foxq1<sa>/H Foxq1<sa> 13I=glossy coat when homozygous CON=glossy coat.Order
FRAG 1 Affects male fertility, males with two or more copies are sterile.Order
Frag X Order
Fragal (CEMO_A1) Order
TgN(FLU)Ox(Freddie) Order From EMMA
FT Vps33a<bf> 5Order
Fgf5<go> 5
Tht 5
FTO-I367F Fto 8Order
FTOKOB8-B6-ACTIN-FLP
E
Order
C3H101H-Axin1<Fu-kb>
/H
Axin1<Fu-kb> 17Knobbly.Order
funny feet Small, abnormal limbs (short and stick like).Order
FVB/N-Tg(ACTB-cre)2M
rt/J
Tg(ACTB-cre)2Mrt UNThis Cre recombinase strain is under the human beta actin gene promoter. This strain expresses Cre recombinase in all cells of the embryo by the blastocyst stage of development.Order
G6pd<b> Low activity of glucose 6 phosphate dehydrogenase.Order
STOCK G6pdx<a-m1Neu> G6pdx<a-m1Neu> XLow glucose-6-phosphate dehydrogenase-a activity.Order From EMMA
B6;129P2-Galr2<tm1Dg
en>/H
Galr2<tm1Dgen> 11No visible phenotype.Order From EMMA
Galr2 11
Gammy (JU) Club foot in one or both hind limbs.Order
TgN(UminiG)Ox(Gareth
)
Order
C3.C-Gars<C201R>/H Gars<C201R> 6Mice heterozygous for this dominant mutation exhibit low limb tone, low grip strength and poor wire manoeuvrability. Order From EMMA
TgN(UminiG)Ox(Gavin) Order
129-Elane<tm1(cre)Ro
es>/H
Elane<tm1(cre)Roes> 10Impaired innate immunity.Order From EMMA
129-Elane<tm1(cre)Ro
es>Ctsg<tm1.1Roes>/H
Elane<tm1(cre)Roes> 10Impaired innate immunity.Order From EMMA
Ctsg<tm1.1Roes> 14
GENA287 Heterozygotes are small at birth and maturity with striped coat. Order
GENA 29 (Cross 3) Kumba mouse can be belly spot, curly tail, or spina bifida.Order
GENA381 High Alkaline phosphatase, low cholesterols, distinguishable by blood testing. Some mutants are smaller and have a darker coat colour.Order From EMMA
GENA394 Impaired Glucose Tolerance (IGT).Order From EMMA
GENA111 Small at birth and weaning. Waddler behaviour. Rough coat.Order From EMMA
C3H;C-Emx2<Pdo>/H Emx2<Pdo> 19Mice heterozygous for this mutation carry a dominant mutation that causes syndromic hearing loss and is possibly a novel mouse model of Leopard Syndrome. Currently known defects in affected mice include conductive hearing loss due to malformation of the ossicular chain and sensineural deafness due to an extra inner and outer row of stereocillia hair cellls in the cochlea. Heart defects are also suspected but have not been confirmed.Order From EMMA
GENA187 High locomotive activity and arousal activity in heterozygotes.Order From EMMA
GENA221 Heterozygotes are smaller than wildtypes. Order From EMMA
C3H;C-Tuba1a<Jna>/H Tuba1a<Jna> 15Behavioural.High LMA. Heterozygotes are detected by measuring beam-splitting activity in LMA cages. Homozygosity has not been tested. GENA227 exhibits spontaneous hyperactivity in the absence of deafness and circling. Order From EMMA
GENA316 GENA316/+ animals have poor rota rod performance.Order From EMMA
GENA323 Large body size (+125%) and flaccid abdonimal tone.Order From EMMA
GENA339 Mice heterozygous for this mutation have cranofacial abnormalities observed as a broad head.Order From EMMA
GENA344 High pelvic elevation.Order From EMMA
GENA353 No response to touch escape.Order From EMMA
GENA357 Intermittent fits.Order From EMMA
GENA360 Low total choloesterol and HDL cholesterol.Order From EMMA
GENA370 Pmp22 11Fits and marked resting tremors. Mice heterozygous for this mutation exhibit hypomyelination abnormalities and have a marked resting tremor.Order From EMMA
GENA371 No tail.Order
GENA377 Heterozygote animals fall off the rota rod. Order From EMMA
GENA396 Mice heterozygous for this mutation have high blood glucose concentrations (hyperglycaemia).Order From EMMA
GENA397 Hypoglycaemic.Order From EMMA
C3H.C-Scn8a<Clth>/H Scn8a<Clth> 15Cloth-ears mice show reduced acoustic startle response and mild hearing loss from about 30 days old. Tests indicate that the peripheral neural auditory pathway is impaired in these mutants, but that cochlear function is normal. Both homozygotes and heterozygotes display paroxysmal tremor episodes with behavioural arrest. Homozygotes demonstrate a milder continuous tremor during movement and rest. Order From EMMA
GENA401 Late onset deafness. Order From EMMA
GENA100 Mice carrying this mutation have dark pigmentation on their footpads and additional areas such as the ears and tail. Some litter mates may also be small. Order From EMMA
GENA115 Small at birth and weaning. Small testis.Order From EMMA
GENA119 circling.Order
B6J.Cg-Bfc/H Short domed head.Order
C3H.Cg-Bfc/H Bfc 9Short broad head, dark pigmentation, abnormal gait and plevic elevation. Mice heterozygous for this mutation have abnormal facial pigmentation, cranofacial abnormalities observed as broad head and skeletal abnormalities observed as an abnormal gait and elevated pelvis. Order From EMMA
C.Cg-Bfc/H Bfc 9Short broad head, dark pigmentation, abnormal gait and plevic elevation. Mice heterozygous for this mutation have abnormal facial pigmentation, cranofacial abnormalities observed as broad head and skeletal abnormalities observed as an abnormal gait and elevated pelvis. Order
GENA127 Heterozygotes have a pigmentation defect where the coat is lighter than agouti.Order From EMMA
GENA135 Mice carrying this mutation have an abnormal gait (hunched, jerky, darting), tail rattle, evidence of aggression in arena, vigourous touch escape response and tachycardia.Order From EMMA
GENA140 Small with short head.Order
GENA143 Abnormal gait and waddling movement.Order From EMMA
GENA144 Passive.Order
GENA15 Small, extra digit.Order
GENA151 High activity.Order
GENA155 Heterozygotes are small with elevated pelvic limbs.Order From EMMA
GENA160 Head shaking , belly spot, white toes.Order From EMMA
GENA172 GENA172/+ animals have white feet and a belly spot.Order From EMMA
GENA185 Dominant behavoiural mutant with high gait, balance problems and strong grip.Order
C3H;C-Icst/H Icst 2Abnormal gait and iris corneal strands.Order From EMMA
GENA200 Heterozygotes have a reduced or absent toe pinch response and/or reduced grip strength in SHIRPA assessment.Order From EMMA
GENA203/mod GENA203 mod/+ have an extra digit on one hind limb. GENA203 mod/Spgl have extra digits on all four limbs. Both have bone abnormalities.Order
GENA214 Very active, circling, limb grasp, no toe pinch.Order
GENA217 Low ppi.Order
GENA228 Behaviour. Headweaving and Circling in heterozygotes.Order From EMMA
GENA243 Low Total and HDL cholesterol.Order From EMMA
GENA250 Low plasma alkaline phosphatase.Order From EMMA
GENA26 Low muscle tone, belly spot, white feet, short crinkly tail.Order From EMMA
C3H.Cg-Zic2<Ku>/H Zic2<Ku> 14The Kumba mouse (also known as GENA29) has three possible phenotypes, belly spot, curly tail, or spina bifida. Arose because of looped tail and or ventral spotting. Rare (~2%) instances of spina bifida were also observed. Mutation maintained by backcrosses to C3H. The C3H background seems to decrease the penetrance of the visible heterozygous phenotypes. The homozygous mutation causes mid gestation lethality, with embryos exhibiting neural tube and other defects.Order From EMMA
GENA31 Heterozygote females have a stripey coat at 8 days indicative of X-inactivation. Hemizygous males do not survive. Phenotype of heterozygous females has not been characterised in detail.Order From EMMA
GENA313 Poor righting reflex and small.Order From EMMA
GENA318 Irritable at shirpa, kinky tail, high locomotive activity.Order From EMMA
GENA321 High Startle. Heterozygotes are detected by measuring response to 110 db tones. They are hyper responsive to sudden pulses of sound. The underlying cause may be neurological or behavioural. Homozygosity has not been tested to date.Order From EMMA
GENA327 High triglycerides.Order
C3H;C-Alpl<Hpp>/H Alpl<Hpp> 4Mice with this mutation have low plasma alkaline phosphatase.Order From EMMA
GENA342 Headweaving/headbobbing and circling in heterozygotes.Order
C3H;C-Gck<Gena348>/H Gck<Gena348> 11Mice heterozygous for this mutation have high blood glucose and increased body weight. Order From EMMA
GENA350 Abnormal gait, vigorous touch escape.Order From EMMA
GENA359 GENA359/+ animals have a lower left eye, blunt nose, craniofacial defect.Order From EMMA
C3H;C-Flna<Dilp2>/H Flna<Dilp2> XDilated pupils in heterozygotes.Order From EMMA
GENA382 Animals from this stock have abnormally high levels of alanine transferase (ALT) and asparate tansferase (AST).Order
GENA383 Inherited abnormal high levels of plasma sodium and chloride.Order From EMMA
GENA391 Lipid and glucose perturbations.Order From EMMA
GENA40 Dark coat.Order From EMMA
C3H;C-Rasgrf1<enu1H>
/H
Rasgrf1<enu1H> 9Small mice when inherited through an affected male-imprinting mutation.Order From EMMA
GENA91 Tremor.Order From EMMA
C3H.Cg-Sho2/H GENA93 animals have cranofacial abnormalities observed as shorthead. Order From EMMA
TgN(UminiG)Ox(George
)
Order
TgN(UminiG)Ox(Gerald
)
Order
C3H/HeH-Gja8<No2>/H Gja8<No2> 3Cataract in lens nucleus, more severe in homozygotes. Order From EMMA
C3H101H-Gli3<Xt>/H Gli3<Xt> 13Extra toes.Order
C3H101H-Gli3<Xt-2H> Gli3<Xt-2H> 13Extra toes.Order
129S2.Cg-Gnas<tm2Kel
>/H
Gnas<tm2Kel> 2There is a behavioural phenotype: response to novel environments as measured through activity in various tasks. This targeted allele has been shown to represent a null for Nesp55 protein.Order From EMMA
B6.Cg-Gnas<tm2Kel>/H Gnas<tm2Kel> 2There is a behavioural phenotype, response to novel environments as measured through activity in various tasks.Order From EMMA
TgN(UminiG)Ox(Gordon
)
Order
C3H101H-Gpi1<c>/H Gpi1<c> 7Order
C3H101H-Gpi1<a-m1H> Gpi1<a-m1H> 7Order
Gpi1-s<TEM> Gpi1<b> UNOrder
Gpi1<a> UN
Gpi1<TEM> UN
B6;129P2-Gpr56<tm1Dg
en>/H
Gpr56 8NoneOrder From EMMA
129-Gca<tm1Roes>/H Gca<tm1Roes> 2Minimal.Order From EMMA
TgN(UminiG)Ox(Grant) Order
B6NDen;B6N-Snip1<tm1
a(EUCOMM)Wtsi>/H
Snip1<tm1a(EUCOMM)Wt
si>
4Order From EMMA
B6;129P2-Grm1<tm1Dge
n>/H
Grm1 10No visible phenotype.Order From EMMA
B6;129P2-Grm4<tm1Dge
n>/H
Grm4 17No visible phenotype.Order From EMMA
B6;129P2-Grm5<tm1Dge
n>/H
Grm5 7No visible phenotypeOrder From EMMA
B6;129P2-Grm8<tm1Dge
n>/H
Grm8 6No visible phenotypeOrder From EMMA
C3H101H-Gs/H Gs XGreasy.Order
GtRosa26LacZ<tm1Col> No obvious phenotype. Order From EMMA
B6J;C-Guth/H Huntington’s disease, enhancer of tremor onset.Order
Hba<c2> Hba<c2> UNOrder
Hba<f> UN
Hba<cm> Hba<cm> UNOrder
Hba<f> UN
Hbb<d3> Hbb<d3> UNOrder
C3H101H-Hbb<d4>/H Hbb<d4> 7Order
C3H101H-Hbb<d5>/H Hbb<d5> UNOrder
Hbb<d6> Hbb<d6> UNOrder
C3H101H-Hbb<d7>/H Hbb<d7> UNOrder
B6N-Hbp1<not yet ass
igned>/H
Hbp1 12Order From EMMA
B6N;B6N-Herc3<tm1a(E
UCOMM)Wtsi>/WtsiH
Herc3<tm1a(EUCOMM)Wt
si>
6None.Order From EMMA
C57BL/6J-Nox3<het>/H Nox3<het> 17Heterozygotes can have abnormal circling behaviour & hyperactivity. Homozygotes also exhibit a subtle head tilt.Order
Hira<neo> Early embryonic lethalityOrder
Histidinaemic GreyOrder
129-Foxa2<tm1Jrt>/H Foxa2<tm1Jrt> 2Homozygous lethal at day 8 of gestation.Order From EMMA
HNF4 cre Hnf4a 2Homozygous lethal at mid gestation due to defects in liver formation.Order From EMMA
Hox11 KO/unr5 Hox11 KO produces spleenless mice. uNR5 causes truncation (deletion of C1 and C2) of IgM H-chain.Order
Hoxa3<tm1(cre)Moon> Hoxa3<tm1(cre)Moon> 6Order
C3H101H-Gnrh1<hpg>/H Gnrh1<hpg> 14Order
Hprt Order
C3H101H-Aifm1<Hq>/H Aifm1<Hq> XOrder
C3H101H-Hr<hr>Ednrb<
s>/H
Hr<hr> 14Hairless.Order
HSA-Mini George Order
HSA-mini Grant Order
STOCK hsh/H hsh 3hind shakerOrder
HSP27 WT High Copy L
ine
No phenotype in transgenic carriers.Order From EMMA
HSP27 WT Low Copy Li
ne
No phenotype in transgenic carriers.Order From EMMA
HSP27 WT PrP Promote
r Line
No phenotype in transgenic carriersOrder From EMMA
HT Gdf5<bp> 2Order
Pldn<pa> 2
Mlph<ln> 1
Ap3b1<pe-H> UN
C3H101H-Hum/H Heterozygotes have very dark stripe down the back, homozygotes very dark all over.Order
B6NDen;B6N-Tnfaip1<t
m1a(EUCOMM)Wtsi>/H
Tnfaip1<tm1a(EUCOMM)
Wtsi>
11Order From EMMA
C3h101H-Hw/H Small at birth and weaning, waltzing and circling phenotype. Homozygotes probably die before birth. Order
Igfn1_KD1 Order
IGT/10 Double heterozygous mice have type II diabetes.Order
B6;129P2-Il8ra<tm1Dg
en>/H
Cxcr1<tm1Dgen> 1No visible phenotype.Order From EMMA
IM Prnp 2Dilute brown coat.Order
C3H101H-In(1)5H White toes and spotting. Animals tend to be smallOrder
STOCK In(2)2H A<w> 2Phenotypic effect on agouti locus.Order
As 2
STOCK In(2)5Rk Pldn<pa> 2black with a tan bellyOrder
Pax1<un> 2
a<t> 2
C3H101H-In(5)9Rk reduced fertility in both sexesOrder
STOCK In(X)IH Order
STOCK In(X)3H Eda<Ta> XOrder
Atp7a<Mo-blo> X
In(YLS)Lub(Y<m>) Order
B6NDen;B6N-Cyb561<tm
1a(EUCOMM)Wtsi>/H
Cyb561<tm1a(EUCOMM)W
tsi>
11Order From EMMA
INH/17 Trembler mutation with high stepping gait.Order From EMMA
INH/18 Trembler mutation with high stepping gait.Order From EMMA
INH/6 Heterozygous females are striped. Hemizygous males have no guard hairs, hair on tails, normal teeth, very little hair behind the ears. Homozygous females look like hemizygous males. Order From EMMA
INH/8 Trembler mutation (poor inheritance).Order From EMMA
Invs<inv> Invs<inv> 4Homozygous embryos develop situs inversus.Order From EMMA
Icst Icst 2Abnormal gait, iris-corneal strands. Heterozygotes have variable eye phenotypes - corneal opacity/bulging, iris-corneal adhesion, irregular pupil, cataracts, some appear to have secondary glaucoma. May have poor penetrance.Order
C3H101H-Is(1;13)4H/H Small at birth and weaning.Order
STOCK Is(7;1)40H males are sterile.Order
C3H101H-Is(In7;X)1Ct
/H
Order
C3H101H-Is(In7;X)1Ct
-Xce<a>/H
Xic<a> XNon-random X-inactivationOrder
C3H101H-Is(In7;X)1Ct
-Xce<b>/H
Xic<b> XOrder
Isl1<tm1(cre)Cos> Isl1<tm1(cre)Cos> 13Order
Isl1<tm1(cre)Sev> Isl1<tm1(cre)Sev> 13Order
STOCK a<18H>/H a<18H> 2Homozygotes are non-agouti with very dark pinna hairs. A/a<18H> looks wild-type. a/a<18H> look umbrous i.e. non-agouti with agouti hairs along side of body and on the belly.Order
STOCK Dnahc11<iv>/H Dnahc11<iv> 12Situs inversus viscerum.Order From EMMA
jas1 Wavy coat and curly whiskers.Order
C3H.Cg-Fbxo11<Jf>/H Fbxo11<Jf> 17Deaf.Order From EMMA
129P2/OlaHsd-Map3k1<
Gt(YTC001)Byg>/H
Map3k1 13Full description available from Europhenome Order
C3H101H-Plp1<jp>/H Plp1<jp> XOrder
JPX Glo1<b> UNOrder
Ldh2<b> UN
Hk1<b> UN
Sdh1<b> UN
B6.A-Ush1g<js>/J Ush1g<js> 11Deafness.Order
JU/FaCt-+<a> +<c> Order
Ju/FaCt-+<c> Order
C3H.Cg-Mecom<Jbo>/H Mecom<Jbo> 3Late onset deafness, extra digit, reduced body weight, craniofacial defect.Order From EMMA
K10T+/- Krt10<tm1Tmm> 11K10T mice show a phenotype in the epidermis and in tongue, esophagus and forestomach. Homozygous pups die on the first day after birth from dehydration due to generalised blistering within the epidermis. Heterozygous mice look normal at birth and develop a progressive thickening of the skin and hyperkeratosis. Their skin is scaly. Heterozygotes breed normally. Order From EMMA
B6;129P2-Kcnj15<tm1D
gen>/H
Kcnj15 16Kir4.2 potassium channel knockout. Phenotype as yet undetermined Order From EMMA
Khk-a<tm1.1Ls> Order
Khk-N<tm1(neo)Ls> Order
C3H101H-Kit<W-19H> Kit<W-19H> 5dominant spottingOrder
CBA/H-Kit<W-27H>/H Kit<W-27H> 5Dominant spotting.Order
C3H-Kit<W-28H> Kit<W-28H> 5dominant spottingOrder
C3H-Kit<W-29H> Kit<W-29H> 5dominant spottingOrder
Kit<W-30H> Kit<W-30H> UNdominant spottingOrder
C3H101H-Kit<W-31H>/H Kit<W-31H> UNDominant spotting.Order
Kit<W-32H> Kit<W-32H> UNDominant spotting.Order
Kit<W-33H> Kit<W-33H> UNdominant spottingOrder
C3H101H-Kit<W-36H> Kit<W-36H> 5Dominant spotting.Order
C3H101H-Kit<W-38H>/H Kit<W-38H> UNdominant spottingOrder
C3H101H-Kit<W-bd>/H Kit<W-bd> 5White band in trunk region.Order From EMMA
C3H101H-Kit<W-ct>/H Kit<W-ct> 5Cattanach's dominant spottingOrder
C3H.Cg-Kit<W-e>/H Kit<W-e> 5Heterozygotes have coat spots. Homozygosity is lethal.Order From EMMA
C3H101H-Kit<W-sh>/H Kit<W-sh> 5SashOrder
Kit<W-sh>l Kit<W-shl> ?? UNOrder
C57BL-Kit<W-v>/H Kit<W-v> 5Viable dominant spottingOrder
C3H;C-Kit<W-39H> Kit<W-39H> 5Heterozygotes have a white belly spot and occasionally a white head blaze. Homozygotes have not been identified and they may die in uteroOrder
C3H-Koa/H Koa 15Heterozygotes have hairy ears and muzzle, homzygotes are slightly more extreme.Order
B6NDen;B6N-Fam117b<t
m1a(EUCOMM)Wtsi>/H
Fam117b<tm1a(EUCOMM)
Wtsi>
1Order From EMMA
C3H101H-Sox<lcc>/H Sox2<lcc> 3light coat circlerOrder
C3H101H-Lct/H Light coat.Order
C3H;C-Lcl/H Lcl UNLens cloudy. Cataracts. Mice heterozygous for this mutation show progressive cataract formation, with total opacity at approximately 3 months. Mice homozygous for this mutation have small eyes and total lens opacity at 4-5 weeks.Order From EMMA
STOCK Rb(6.15)1Ald-M
ip<Cat-Lop>/H
Mip<Cat-Lop> 10Lens opacity.Order
C3H;C-Pax6<Leca1>/H Pax6<Leca1> 2Heterozygotes have a central indentation and may have small eyes, irregular pupils and lens corneal adhesionsOrder From EMMA
C3H;C-Pax6<Leca2>/H Pax6<Leca2> 2Heterozygotes have small eyes, corneal opacities and cataracts.Order From EMMA
C3H;C-Pax6<Leca3>/H Pax6<Leca3> 2Mutants may have central corneal opacity, small eyes, dilated pupils and lens-corneal adhesion. Order From EMMA
Lepr<db> Lepr<db> 4Recessive misty mutation is present. Homozygotes become obese at 3-4 weeks of age. Elevation of plasma insulin begins at 10-14 days and of blood sugar at 4-8 weeks. Homozygotes die by 10 months of age.Order
C3H101H-Li/H Li XLined.Order
LII Mcoln3<Va> 3Order
Gli3<Xt> 13
T 17
LIII Cdh23<v> 10Order
Mlph<ln> 1
Hps1<ep> 19
Sgk3<fz> 1
Lim-1 (Lhx-1) Lhx1<tm1Bhr> 11Homozygous lethal at day 10 of gestation.Order From EMMA
Line # 46 - Fused lo
be
Order
Line # 48b - Unbranc
hed
Fusion of cranal and medial lung lobes; kidneys are small, lack medulla; lacrimal glands have less epithelium branchingOrder
LIVA Tyrp1<b> 4Order
Tgfa<wa1> 6
Tyr<c-ch> 7
Myo5a<d> 9
Bmp5<se> 9
Ednrb<s> 14
a 2
LL Gdf5<bp-H> UNlimb - short legs and digits affected.Order
Pldn<pa> UN
Mlph<ln> UN
LMWP3 Low Molecular Weight Protein (LMWP) in the urine which is an indicator of proximal tubule dysfunction in the kidney.Order
Lnk -/- Order
Lo Moe None. Order From EMMA
C3H101H-Dync1h1<Loa>
/H
Dync1h1<Loa> 12Legs at odd angle.Order From EMMA
C.Cg-Lpk/H Lpk UNShort-limbed phenotype in both fore- and to a lesser extent hind-limbs. Mice have short limbs (achondroplasia). Register Interest
C3H.Cg-Lpk/H Lpk UNShort limbs (achondroplasia).Order From EMMA
Loop tail Vangl2<Lp> 1Ltap<Lp>/+ mice exhibit a tail defect. Ltap<Lp>/Ltap<Lp> mice exhibit severe neural tube defect (die at birth).Order
STOCK Lop4/H Lop4 2Lens opacity.Order
STOCK Lop6/H Lop6 UNLens opacityOrder
STOCK Lop9/H Lop9 UNOrder
B6;129P2-Lphn2<tm1Dg
en>/H
Lphn2 3NoneOrder From EMMA
LR8 Hps6<ru> 19Order
Gdf5<bp> 2
Bmp5<se> 9
Hps5<ru2> 7
Myo5a<d> 9
a 2
Oca2<p> 7
Hps1<ep> 19
ls<rrw> Edn3<ls-rrw> UNHomozygotes usually die before weaning but have a predominantly white coat with pigmental rump.Order
B6NDen;B6N-Ttll4<tm1
a(EUCOMM)Wtsi>/H
Ttll4<tm1a(EUCOMM)Wt
si>
1Order From EMMA
LVC Egfr<wa2> 11 Jerker, homozygotes exhibit jerky behaviour. Spontaneous. waved 2, homozygotes have wavy fur. Spontaneous. pe<H>, homozygotes have a light coat. Spontaneous. mahoganoid, homozygotes have a dark coat. Spontaneous.Order
Espn<je> 4
Mgrn1<md> 16
Ap3b1<pe-H> UN
LVI Kitl<Sl-gbH> UNToes fused,(8) black coat,(8) belly spots,(10) light coat,(10) behavioural (18)Order
Mc1r<E-so> UN
M1073B Embryonic lethal.Order From EMMA
M1185B Embryonic lethalOrder From EMMA
M1239B Embryonically lethalOrder From EMMA
M1616B Embryonic lethalOrder From EMMA
M1645B Embryonic lethalOrder From EMMA
M241B Embryonically lethalOrder From EMMA
M369B Embryonic lethalOrder From EMMA
M412B Embryonic lethalOrder From EMMA
M54B Embryonic lethalOrder From EMMA
M624B Embryonic lethalOrder From EMMA
M876B Embryonically lethalOrder From EMMA
C3H101H-ma-Mcoln3<Va
>/H
ma 3Mcoln3<Va> heterozygotes are deaf mice that have variegated coats, they also circle and/or headtoss. ma/ma mice have scruffy coats. Order
Mcoln3<Va> 3
C3H101H-Maf<tm1Glm>/
H
Maf<tm1Glm> 8Homozygotes have eye defects, are small and shaky, and may die before adulthood.Order
C3H-Maf<Ofl>/H Maf<Ofl> 8Heterozygotes-opaque flecks in lens; homozygotes- very small eyes, most die at birth through failure to feed, survivors small, trembly, and develop nephritis. Dominant cataractOrder
C3H101H-Maf<Ofl>/H Maf<Ofl> 8Order From EMMA
Mafb<Krml-kr>;we; (K
reisler)
we 2Order
Mafb<kr> 2
129P2/OlaHsd-Mkrn1<G
t(RRB087)Byg>/H
Mkrn1<Gt(RRB087)Byg> 6No abnormal phenotype detected. Order
TgN(DSPM36)1886OxAna
t
Order
TgN(DSPM36)1892OxAna
t
Order
MB Order
MBT1 Lack of marble burying. Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. Order From EMMA
MBT2 Low anxiety, marble mutantOrder From EMMA
MBT3 Low anxiety, marble mutant.Order From EMMA
MBTR2 Lack of marble burying.Order From EMMA
MBTR3 Lack of marble burying.Order From EMMA
MC-1 Phenotypically normalOrder
B6;129P2-Mc2r<tm1Dge
n>/H
Mc2r 18No visible phenotype.Order From EMMA
MCA/mdx Order From EMMA
B;CBACa-Dmd<mdx>Tg(C
KMM-tTA)A3Rhvh/H
Tg(CKMM-tTA)A3Rhvh UNMCK-tTA/mdx mice contain the muscle specific creatine kinase (MCK) promoter driving the tetracycline regulated transactivator (tTA).Order From EMMA
Dmd<mdx> X
Mcpt1<tm1Hrpm> Lack of Mcpt-1 expression.Order
C3H101H-Mgrn1<md-nc>
/H
Mgrn1<md-nc> 16nonagouti curlyOrder
mdx Dmd<mdx> XX-linked muscular dystrophy.Order
STOCK Dmd<mdx-3Cv>/H Dmd<mdx-3Cv> XOrder
Mesp1<tm2(cre)Ysa> Mesp1<tm2(cre)Ysa> 7Order
C3H;C-Chd7<Mt>/H Chd7<Mt> 4Heterozygotes exhibit head weaving and circling behaviour. Homozygotes exhibit midgestational lethality possibly due to vascular defects seen in the anterior neural tube.Order From EMMA
C3H101H-Kitl<Sl-10H>
/H
Kitl<Sl-10H> 10steelOrder
C3H101H-Kitl<Sl-12H>
/H
Kitl<Sl-12H> 10steelOrder
C3H101H-Kitl<Sl-13H>
/H
Kitl<Sl-13H> UNOrder
C3H101H-Kitl<Sl-14H>
/H
Kitl<Sl-14H> UNSteel.Order
C3H101H-Kitl<Sl-15H>
/H
Kitl<Sl-15H> UNSteel.Order
C3H101H-Kitl<Sl-17H>
/H
Kitl<Sl-17H> 10steelOrder
C3H101H-Kitl<Sl-18H>
/H
Kitl<Sl-18H> 10steelOrder
C3H101H-Kitl<Sl-20H>
/H
Kitl<Sl-20H> UNSteel.Order
C3H101H-Kitl<Sl-21H>
/H
Kitl<Sl-21H> UNOrder
C3H101H-Kitl<Sl-22H>
/H
Kitl<Sl-22H> UNSteel.Order
C3H101H-Kitl<Sl-23H>
/H
Kitl<Sl-23H> UNSteel.Order
C3H101H-Kitl<Sl-24H>
/H
Kitl<Sl-24H> UNSteel.Order
C3H101H-Kitl<Sl-25H>
/H
Kitl<Sl-25H> 10steelOrder
C3H101H-Kitl<Sl-26H>
/H
Kitl<Sl-26H> UNSteel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia.Order
Kitl<Sl-27H> Kitl<Sl-27H> UNSteel, greyish fur, pale feet and tail with occasional head dots and belly spots.Order
C3H101H-Kitl<Sl-29H>
/H
Kitl<Sl-29H> UNSteel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia, no survival past a few days after birth.Order
C3H101H-Kitl<Sl-30H>
/H
Kitl<Sl-30H> UNSteel, greyish fur, pale feet and tail with occasional head dots and belly spots.Order
C3H101H-Kitl<Sl-31H>
/H
Kitl<Sl-31H> UNSteel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia.Order
C3H101H-Kitl<Sl-32H>
/H
Kitl<Sl-32H> UNSteel, greyish fur, pale feet and tail with occasional head dots and belly spots, anaemia, high pre-implantation loss - homozygotes die early in development, some live foetuses were also anaemic.Order
C3H101H-Kitl<Sl-33H>
/H
Kitl<Sl-33H> UNSteel, greyish fur, pale feet and tail with occasional head dots and belly spots. Anaemia.Order
Mgf<Sl-34H>, T(19;11
)75H
Kitl<Sl-34H> UNOrder
C3H101H-Kitl<Sl-8H>/
H
Kitl<Sl-8H> 10Order
C3H101H-Kitl<Sl-9H>/
H
Kitl<Sl-9H> 10steelOrder
C3H101H-Kitl<Sl-pan>
/H
Kitl<Sl-pan> 10Steel-panda.Order
C3H101H-cw-Bmp5<se>t
k/H
cw 9Kinky tail.Order
tk 9
Bmp5<se> 9
GENA163 Mitf<Mi-H> UNMicrophthalmia. Dominant mutant with small eyes, Mi-like. Heterozygotes are paler, they have head and belly spots. Homozygotes are white with no eyes. Order
B6N;B6N-Mier1<tm1a(E
UCOMM)Wtsi>/WtsiH
Mier1<tm1a(EUCOMM)Wt
si>
4None.Order From EMMA
Mitf<Mi-wh>, px Mitf<Mi-wh> 6het. light coated & light ears & sometimes a belly spot. hom. Mitf<Mi-wh> white with slight micropthalmia, Forelimbs often affected with absence of digets & sometimes ulna. Large foramen in scapula. All feet have epidermal papillae etc.Order
Wnt7a<px> 6
MLO c<62chH>/c<62chH> homozygotes have a grey coat colour, c/c<62chH> trans-heterozygotes have a cream coat colour and ruby coloured eyes. Order From EMMA
C3H101H-Minute/H Minute 7Minute.Order
MOD Fused Toes SyndactylyOrder
TgN(DSPM36)1892OxAna
t
Order
C3H;C-Mtu/H Mtu 12Kinky tail, deaf, belly spot. Heterozygotes exhibit abnormal tail morphology, are deaf, and have belly spots that are characteristic of neural crest defects. Homozygotes, do not appear to be viable, as they have an open neural tube. Order From EMMA
C3H101H-Mdh1<am1H>/H Mdh1<am1H> 11Order
TgN(DSPM36)1327OxAna
t
Order
MR Albino, rough kinked whiskersOrder
C57BL/6Apb-Zap70<mrt
le>/Apb
Zap70<mrtle> 1Identified by severe reduction in T cell numbers in blood. Zap70 protein expression of mrt/mrt thymocytes was 25% of +/+ thymocytes. Het mice, mrt/+ have normal levels of CD4+ and CD8+ thymocytes but Zap70 protein expression is two-fold lower.Order From EMMA
B6.Cg-Mro<tm1H>/H Mro<tm1H> 18No visible phenotype.Register Interest
Mta1<tm1aWtsi> Mta1 12NoneOrder From EMMA
C3.Cg-Mfl/H Order
MUHi Long term growth selected line.Order
MULi Long term growth selected mouse line.Order
MURB125 Limbs and bones are shorter than normalOrder
MURB151 Heterozygotes have light grey coat , darker grey points on ears, nose and tail. Can be classified at 2-3 days old as the pigmentation of the skin is visibly different.Order
CAST/EiJH Order
SPRET/EiJH Order
MUT1096 Small with broad, domed head.Order
MUT1152 Homozygous post-implantation lethal. Heterozygotes are small with cranial doming, pop eyes, distal nasal bone with occasional indications of cleft.Order
MUT1154 Small at birth and small at weaning with cranial doming, variably wide between eyes and shortened nasal passage.Order From EMMA
MUT1264 Craniofacial and behavioural mutant with distal low degree tail kink. Homozygous pre-implantation lethal. Heterozygotes have a flat skull, short, blunt tails with a low degree distal kink and some have white feet. Behavioural abnormalities include head bobbing and erratic behaviour but they can swim. Small at birth and weaning with a high incidence of exencephaly in fetuses. Order From EMMA
MUT1275 ear/ tail/ white spottingOrder
MUT1293 Small at birth and weaning. Broad head, bulging eyes, some have ear problems, ie. A build up of cartilage.Order From EMMA
MUT1305 Craniofacial. Small, white feet, some domed heads, wide between eyes which may bulge.Order From EMMA
MUT1397 Tail kinks.Order From EMMA
MUT1425 Mutation causes typical chylous ascites-like symptoms - milky abdomen at birth and puffy feet and tail in older animals. Order
MUT1454 Small at birth and weaning, white feet, short kinky tail. Some have odd behaviour - swaying, leaning, head bobbingOrder
MUT1477 milky abdomen at birth, small at weaningOrder
MUT1488 Small at birth and weaning. They have small eyes, very few have domed heads, some have white toesOrder From EMMA
MUT1490 Mutation causes typical chylous ascites-like symptoms - milky abdomen at birth and puffy feet and tail in older animals.Order
MUT1544 Small at birth with bruised type appearance. Bloody areas beneath the skin, most common around the belly and abdomen - some around the neck and back legs. Small at weaning, most have a domed headOrder From EMMA
MUT1556 Small with white feet, some have belly spot. Some show head bobbing and blunt and/or kinky tails.Order
MUT1602 Small at birth and weaning with white hind feet, short tail and head bobbing. Mice have shorter kinky tails. They have waltzing/head bobbing behaviour. Some are small in size and have white feet.Order From EMMA
MUT1679 Mice are small at birth and weaning, they have white feet and shorter kinky tails. Some have domed heads i.e skeletal effects and some display behavioural abnormalities i.e head bobbing. Occasional nasal cleft.Order
MUT1681 Small with white feet. Tails commonly severely shortened, kinked or curled. Some have broad, deep, short head, often with nasal stripeOrder
MUT1696 Small in size with head bobbing. Heterozygotes are small at birth and weaning with head bobbing. Size and behavioural mutation. Unlikely homozygotes survive as evidence of pre implantation loss. Best bred through the male as females behaviour makes them poor carers for their young.Order
MUT1704 Small at birth and weaning. Domed/pointy heads, some with fused toes.The original female was small at birth and weaning with fused hind toes, slightly domed head, whitish toes and tail tip. The offspring phenotype varied, many were small, the fusing of toes only involved the soft tissue not bone. These embryos were generated by IVF with MUT/1704.3d male; small with kink in tail at birth. Small and runty at weaning with dark coat, pointy face and closed eyes.Order
MUT1756 Offspring look normal until 6 weeks when fur becomes sparse, and thus classification prior to 6 weeks not possible in heterozygotes. Small at birth and weaning. Fate of homozygotes not yet determined.Order
MUT921 Key feature is a short broad head, wide between eyes, shortened nasal passage with occasional indication of cleft. White feet and belly spots also seen. Small at birth and weaning. Recovery at birth low due to prenatal loss of foetuses with more extreme head abnormality.Order From EMMA
STOCK Muted<mu>/H Muted<mu> 13Muted. Lighter coat.Order
MUTN212 Circling, limb grasp & trunk curl.Order
MUTN673 Small, deaf.Order
MUTN777 Right eye missing, very active, circlingOrder
MUTN873 Small, deep set eyes, short face, nose bends to left, upper teeth bent back, nose crooked, hunched, high gait & pelvic elevation, no abdominal tone, slow heart rate.Order
MUTS 1/14 Small eye mutationOrder From EMMA
B6NDen;B6N-Mxra7<tm1
a(EUCOMM)Wtsi>/H
Mxra7<tm1a(EUCOMM)Wt
si>
11Order From EMMA
Myl2<tm1(cre)Krc> Myl2<tm1(cre)Krc> 5Order
Myo7a<sh1-9J> Myo7a<sh1-9J> 7Shaker.Order
Myo5a<d-100H> Bmp5<se-m> UNOrder
Myo5a<d-100H> UN
Myo5a<d-50H> Bmp5<se> 9Order
Myo5a<d-50H> UN
Myo5a<d-51H> Bmp5<se> 9(fits?) opisthotonic lethalOrder
Myo5a<d-51H> UN
Myo5a<d-53H> Bmp5<se> 9(fits?) opisthotonic lethalOrder
Myo5a<d-53H> UN
Myo5a<d-82H> Bmp5<se> 9Order
Myo5a<d-83H> Bmp5<se> 9(fits?) opisthotonic lethalOrder
Myo5a<d-83H> UN
Myo5a<d-84H> Bmp5<se> 9(fits?) opisthotonic lethalOrder
Myo5a<d-84H> UN
Myo5a<d-85H> Bmp5<se> 9(fits) opisthotonic lethalOrder
Myo5a<d> 9
Myo5a<d-85H> UN
C3H101H-Myo5a<d-86H>
/H
Bmp5<se> 9(fits?) Opisthotonic lethal.Order
Myo5a<d> 9
Myo5a<d-86H> UN
Myo5a<d-88H> Myo5a<d> 9(fits?) opisthotonic lethalOrder
Bmp5<se> 9
Myo5a<d-88H> UN
Myo5a<d-89H> Myo5a<d> 9Order
Bmp5<se> 9
Myo5a<d-89H> UN
Myo5a<d-90H> Myo5a<d> 9(fits?) opisthotonic lethalOrder
Bmp5<se> 9
Myo5a<d-90H> UN
C3H101H-Myo5a<d-91H>
/H
Bmp5<se> 9Order
Myo5a<d> 9
Myo5a<d-91H> UN
Myo5a<d-92H> Bmp5<se> 9(fits?) opisthotonic lethal.Order
Myo5a<d> 9
Myo5a<d-92H> UN
Myo5a<d-93H> Myo5a<d> 9(fits?) opisthotonic lethalOrder
Bmp5<se> 9
Myo5a<d-93H> UN
C3H101H-Myo5a<d-97H>
/H
Myo5a<d> 9Order
Bmp5<se> 9
Myo5a<d-97H> UN
Myo5a<d<105H> Myo5a<d-105H> UNOrder
Myo5a<d<52H> Myo5a<d-52H> UNOrder
C3H101H-Myo5a<d-58H>
Bmp5<se>/H
Myo5a<d-58H> UNHomozygous lethal.Order
Myo5a<d<61H> Myo5a<d-61H> UNOrder
Myo5a<d<78H> Myo5a<d-78H> UNOrder
Myo5a<d<80H> Bmp5<se> 9Order
Myo5a<d-80H> UN
CBB8-Myo7a<26SB> Myo7a<26SB> 7Shaker 1 allele. Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wildtypes are indistinguishable from each other.Homozygotes show no preyer reflex. These Myo7a mutants do have severe hearing and vestibular abnormalities. While their retinas do not show any anatomical degeneration, there have been reports of retinal abnormalities. Order From EMMA
CBB8-Myo7a<3336SB> Myo7a<3336SB> 7Shaker.Order From EMMA
Myo7a<sh1-4494SB> Myo7a<4494SB> 7shakerOrder From EMMA
Myo7a<sh1-4626SB> Myo7a<4626SB> 7Shaker. Deafness, headshaking, circlingOrder From EMMA
Myo7a<sh1-6J> Myo7a<sh1-6J> 7Shaker.Order
Myo7a<sh1-8165SB> Myo7a<sh1-8165SB> UNshaker. Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wildtypes are indistinguishable from each other. Homozygotes show no preyer reflex. Homozygote females will not rear littersOrder
Myo7a<Sh1-816SB> Myo7a<816SB> 7Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wild types are not distinguishable from each other. Homozygotes show no preyer reflexOrder From EMMA
Myo7a<sh1> Myo7a<sh1> 7shakerOrder
TgN(DSPM36)1668OxAna
t
Order
C3H101H-Nan/H Nan 8neonatal anaemiaOrder
C3H;C-Nano/H Nano XHeterozygotes have small narrow faces. With aging, they develop patches of white hairs on their back. Hemizygous males are presumed to die in utero.Order From EMMA
B6.129P2-Nat2<tm1Esi
m>/H
Nat2<tm1Esim> 8None.Order From EMMA
B6;129-Scn10a<tm3(cr
e/ERT2)Jnw>/H
Scn10a<tm3(cre/ERT2)
Jnw>
9None observed (heterozygous Nav1.8-CreERT2 can express enough Cre to delete the floxed fragement, but it does not affect the expression of Nav1.8 in Nav1.8 positive neurons in DRG).Order From EMMA
B6;129P2-Nek6<tm1Dge
n>/H
Nek6 2No visible phenotype.Order From EMMA
Nephertiti No visible phenotype. Mice develop nephrotic range proteinuria at a young age and has abnormal liver histology, similar to Lafora body disease. Order From EMMA
129S/SvEvNimrH-Nespa
s<tm1Jop>/H
Nespas<tm1Jop> 2Heterozygotes with paternal inheritance of deletion die within 1-2 days of birth. Heterozygotes with maternal inheritance of deletion appear normal.Order
B6NDen;B6N-Nipsnap1<
tm1a(EUCOMM)Wtsi>/H
Nipsnap1<tm1a(EUCOMM
)Wtsi>
11Order From EMMA
Nkx2-5<tm1(cre)Rjs> Nkx2-5<tm1(cre)Rjs> 17Order
Nmnat1<tm2Cole> NoneOrder
C3H-Crygb<nop>/H Crygb<nop> 1nuclear opacity. Dominant cataractOrder
No fur Curly whiskers and progressive hair loss.Order From EMMA
C3H;102-Cryge<No3>/H Cryge<No3> 1Nuclear opacity 3. Dominant cataract.Order From EMMA
Nodal<tm3Rob> Nodal<tm3Rob> 10Het shows no phenotype, homozygous results in disrupted L/R patterning.Order
NOD Age related onset of diabetes.Order
NPA31-B4 Offspring inheriting the targeted construct paternally do not feed, are hypoactive and die within a few hours.Order
C3H-Npp/H Npp 5nuclear-posterior polar opacity. Dominant cataractOrder
B6;129P2-Npy6r<tm1Dg
en>/H
Npy6r 18No visible phenotype.Order From EMMA
B6;129P2-Nr1d2<tm1Dg
en>/H
Nr1d2 14No visible phenotype.Order From EMMA
C3H;102-Casr<Nuf>/H Casr<Nuf> 16Small flecks in lens nucleus, difficult to see in heterozygote, clearer in homozygotes. The Nuf mice also exhibit ectopic calcification.Order From EMMA
NVPD Order
Och, Re<wc> Krt27<Re-wc> 11Och, ochre. Re<wc>, wavy coat.Order
Och 4
C3H101H-Gnas<Oedsml>
/H
Gnas<Oedsml> 2When inherited through the female, the offspring are oedematous. When inherited through the male, the offspring show postnatal growth retardation.Order
C3H-Crygs<Opj>/H Crygs<Opj> 16Opaque fibre cell junctions. Dominant cataract.Order From EMMA
STOCK Opdc/H Opdc 19Optic disc coloboma. Mutants have retinal vascular abnormalities and optic discs of unusual size. Order From EMMA
B6NDen;B6N-Orc5l<tm1
a(EUCOMM)Wtsi>/H
Orc5l<tm1a(EUCOMM)Wt
si>
5Order From EMMA
C3H101H-ostes/H ostes UNMuscular dystrophy, small size and muscle wasting.Order From EMMA
C.Cg-ostes/H ostes UNSmall with muscle tremor.Order
P-Rex1 CE3/B6 Functional neutrophil deficiencyOrder
B6J.129-S100A10<tm1J
nw>/H
S100a10<tm1Jnw> 3None. Order From EMMA
B6;129P2-P2rx6<tm1Dg
en>/H
P2rx6 16No visible phenotype.Order From EMMA
B6;129P2-P2ry12<tm1D
gen>/H
P2ry12 3NoneOrder From EMMA
129-Ncf1<tm1Hbd>/H Ncf1<tm1Hbd> 5Impaired innate immunity. Order From EMMA
C3H101H-p<In(7p;Sox6
)100H>
Oca2<p-d> 7Order
In(7p;7Sox6)100H 7
p<55H> Tyr<c-ch> 7Order
p<55H> UN
C3H101H-Oca2<p-61H>/
H
p<61H> UNp<61>/p slightly darker than p/pOrder
p<65H> p<65H> UNCoat and eyes of p<65>/p darker than p/p. Coat and eyes of p<65>/p<65> only slightly lighter than wild-type.Order
C3H101H-Oca2<p-66H>/
H
p<66H> UNOrder
p<78H> p<78H> UNp<78>/p looks like b/b. Coat and eyes of p<78>/p<78> only slightly lighter than wild type.Order
Oca2<p-79H> p<79H> UNOrder
C3H101H-Oca2<p-80H>/
H
p<80H> UNOrder
C3H101H-Oca2<p-81H> Oca2<p-81H> 7Phenotype of p<81H>/p is similar to p/p, homozygotes die pre-natallyOrder
C3H101H-Oca2<p-82H> Oca2<p-82H> 7phenotype of p<82H>/p is similar to p/p, homozygotes die pre-natallyOrder
p<83H> p<83H> UNOrder
C3H101H-Oca2<p-84H> Oca2<p-84H> 7phenotype of homozygotes is similare to p/pOrder
p<85H> p<85H> UNOrder
C3H101H-Oca2<p-86H> Oca2<p-86H> 7Phenotype similar to p/pOrder
p<87H> p<87H> UNOrder
p<d> UN
C3H101H-Oca2<p-88H> Oca2<p-88H> 7phenotype of homozygotes is similar to p/pOrder
p<91H> p<91H> UNOrder
p<92H> p<92H> UNOrder
C3H101H-Oca2<p-93H>/
H
p<93H> UNOrder
p<95H> p<95H> UNOrder
C3H101H-Oca2<p-96H>/
H
p<96H> UNOrder
p<97H> p<97H> UNOrder
C3H101H-Oca2<p-98H>/
H
p<98H> UNOrder
C3H101H-Oca2<p-99H>/
H
p<99H> UNOrder
C3H101H-Oca2<p-bs>/H Oca2<p-bs> 7p-black-eyed sterileOrder
p<cp>, p<bs> Oca2<p-cp> 7Coat colour same as p/p. p-black-eyed sterile, originally p<24>H,p<bs>/p<bs> viable but smallish, have slightly jerky behaviour, usually sterile & darker in colour than p<bs>/p<cp>, p<cp>/p<cp> usually die around birth from cleft palate, few have lived.Order
Oca2<p-bs> 7
p<d>, p<25H> Oca2<p-d> 7p<d>/p<d> eyes light at birth, dark at weaning. Coat similar to b/b but less "orange"Order
Oca2<p-25H> 7
p<d>, p<6H> Oca2<p-d> 7p<d>/p<d> eyes light at birth, dark at weaning. Coat similar to b/b but less "orange"Order
Oca2<p-6H> 7
STOCK Oca2<p-dn>/H Oca2<p-dn> 7Eyes pink at birth but darken by weaning. Coat slightly darker than p/p.Order
C3H101H-Oca2<p-dn>/H Order
C3H101H-Oca2<p-un>/H Myo5a<d> 9pink-eyed unstableOrder
C3H101H-Oca2<p-x>/H Oca2<p-x> 7Eyes dark at birth and weaning, coat only slightly lighter than wild typeOrder
B6NDen;B6N-Pa2g4<tm1
a(EUCOMM)Wtsi>/H
Pa2g4<tm1a(EUCOMM)Wt
si>
10Order From EMMA
C3H-Paf/H Paf XPatchy fur.Order
B6;129P2-Pak2<tm1Dge
n>/H
Pak2 16NoneOrder From EMMA
C3H101H-Pax3<Sp-1H> Pax3<Sp-1H> 1splotchOrder
C3H101H-Pax3<Sp-2H>/
H
Pax3<Sp-2H> 1splotchOrder From EMMA
C3H101H-Pax3<Sp-4H> Pax3<Sp-4H> 1Order
C3H101H-Pax3<Sp-5H> Pax3<Sp-5H> 1splotchOrder
C3H101H-Pax3<Sp-r>/H Pax3<Sp-r> 1splotch-retarded, spottingOrder From EMMA
Pax3<Sp>, Tyrp1<b-cH
>
Pax3<Sp> 1Splotch.Order
Tyrp1<b-cH> 4
C3.D2-Pax6<Coop>/H Pax6<Coop> 2Heterozygotes have corneal opacity with iris anomaly and small eyesOrder
C3H;C-Pax6<Leca4>/H Pax6<Leca4> 2Mutants have small eyes, but not always corneal opacity (corneal opacity affects most other Pax6 mutants). Often have anterior cataract.Order From EMMA
Pax6<Sey-Neu> Pax6<Sey-Neu> 2Small eyeOrder
PC a 2Order
Oca2<p> 7
Tyr<c-ch> UN
PCE/JP a<t> 2Order
Sox18<Ra> 2
Edn3<ls> 2
Myo5a<d> 9
Egfr<wa2> 11
Wnt3a<vt> 11
C3H101H-Slc40a1<Pcm>
/H
Slc40a1<Pcm> 1Red ears and feet.Order From EMMA
B6;129P2-Pde2a<tm1Dg
en>/H
Pde2a 7No visible phenotype.Order From EMMA
B6;129P2-Pde3a<tm1Dg
en>/H
Pde3a 6No visible phenotype.Order From EMMA
B6;129P2-Pde4b<tm1Dg
en>/H
Pde4b 4No visible phenotype.Order From EMMA
B6;129P2-Pde4d<tm1Dg
en>/H
Pde4d 13No visible phenotype.Order From EMMA
B6;129P2-Pde8a<tm1Dg
en>/H
Pde8a<tm1Dgen> 7No visible phenotype.Order From EMMA
CBA/H-Pdss2<kd>/H Pdss2<kd> 10Kidney disease. Homozygotes develop nephrosis recognizable at about 10 weeks of age by drinking, loss of weight, anaemia, and death usually at 5 to 7 months. Order
PED-JP/16 Order
C3H101H-Pedc/H Pale ears, dark coat. Pre-implantation loss of homozygotes. Order
PEDM/105 Elevated plasma phosphate.Order
PEDM/14 Hyperglycaemia. Elevated plasma glucose at 16 and 24 weeks of age. No detection of glucose in the urine.Order From EMMA
PEDM/15 High anxiety, tremors, small at weaning.Order From EMMA
PEDM/25 This strain demonstrates late onset (>6 months of age) tremors and some individuals have a high nose-poking response in a behavioural test.Order From EMMA
PEDM/29 Highly active and demonstrates a high degree of anxiety Order From EMMA
PEDM/32 AlbuminuriaOrder
PEDM/35 Hyperglycaemia and glycosuria.Order From EMMA
PEDM/36 Limb grasping, walks backwards, inactiveOrder From EMMA
PEDM/41 Deformed digits shortened limbsOrder From EMMA
PEDM/42 Homozygotes have a belted white band of hair around the mouse middle. Their appearance is similar to that of the known mutation on Chromosome 15, Adamts20<bt> (Belted).Order From EMMA
PEDM/83 Short/long faces and small mis-shapen eye sockets.Order
PEDM52 Presumed homozygotes have spina bifida.Order
PEDV/118 Order
PEDV/119 Order
PEDV/128 Order
PEDV/146 Dark skin in marble like patterns, slightly darker fur.Order
PEDV/156 Headbob & head tilt.Order
Pge<1H> pge1<H> UNOrder
C3H101H-pge<2H>/H pge2<H> UNOrder
C3H101H-Pge<3H>/H pge3<H> UNOrder
Pgk1<a> Pgk1<b> UNOrder From EMMA
Pgk1<a> UN
Pgm1<n1H> Pgm1<c> UNOrder
Pgm1<n-H> UN
Pgm1<n2H> Pgm1<n2H> UNOrder
Pgm1<c> UN
Pgm1<n3H> Pgm1<n3H> UNOrder
Pgm1<c> UN
Pgm1<n4H> Pgm1<n4H> UNOrder
Pgm1<c> UN
Pgm2<am> Pgm2<am> UNOrder
Pgm2<a> UN
C3H101H-Ph/H Ph 5White 'belt'. Order
C3H101H-Ph<3H> Ph<3H> 5patchOrder
STOCK Phex<Gy>/H Gy XgyroOrder
STOCK Phex<Hyp>/H Phex<Hyp> XhypophosphatemiaOrder
Pk3<r>, Pk3<b> Pkm2<a> UNOrder
Pkm2<b> UN
Pkm2<r> UN
PKDBac Line2 Hets appear normal. Homs are small and develop hind-limb dragging at 4-6 weeks old Order
C57BL/6Apb-Ikzf1<Pls
tc>/Apb
Ikzf1<plstc> 11Embryonic lethal E15.5-17.5. Anaemia. Failure of normal erythroblast growth & differntiation in feotal liver. Expansion of myeloid cells.Order From EMMA
C3H;C-Play41/H Play41 UNIdentified in circadian rhythm screen. Mutant mice demonstrate a long circadian period (24-24.5hr), and reduced activity.Order From EMMA
C3H;C-Play50/H Play50 UNIdentified in circadian rhythm screen. Reduced bouts of wheel- running activityOrder From EMMA
C3H;C-Play63/H Reduced bouts of wheel- running activity.Order From EMMA
C3H.Cg-Play1/H These mice have a higher than normal degree of daytime activity in a 12:12 light:dark cycle.Order From EMMA
C(C3)-Play16/H No entrainment response to light pulses given at CT16.Order From EMMA
PLAY19 Identified in circadian rhythm screen. Potentially no entrainment response to light pulses given at CT16Order From EMMA
C3H.Cg-Play22/H Play22 UNMice carrying this mutation show a low endurance of wheel running activity. Wheel running activity is about 10% of control animals.Order From EMMA
C3H.Cg-Play31/H Identified in a circadian rhythm screen. Wheel turning activity is dramatically reduced in a 12:12 light:dark cycle.Order From EMMA
C3H;C-Play32/H Identified in a circadian rhythm screen. These mice have reduced bouts of wheel running activity in a 12:12 light:dark cycle. Order From EMMA
C3H;C-Play36/H Play36 UNIdentified by circadian rhythm screen. Mutant mice demonstrate an increased phase shift after light pulse.Order From EMMA
C3H;C-Play40/H Identified in circadian rhythm screen. Mutants have potentially no entrainment response to light.Order From EMMA
C3H;C-Play42/H Identified in a circadian rhythm screen. These mice have two sets of activity onsets when first exposed to constant darkness conditions.Order From EMMA
C3H;C-Play44/H Identified in circadian rhythm screen. Potentially shows a large entrainment response to light and phase advancement in a 12:12 light:dark cycle.Order From EMMA
C3H;C-Play46/H Play46 UNPoor entrainment to light in 12:12 light dark: cycle.Order From EMMA
C3H;C-Play47/H Identified in circadian rhythm screen. These mice free run in a 12:12 light:dark cycle.Order From EMMA
C3H;C-Play57/H Play57 UNIdentified in circadian rhythm screen. Mutant mice demonstrate a shorter cicadian wild type.Order From EMMA
C3H;C-Play65/H Changed period length after light pulse at CT16.Order From EMMA
C3H;C-Play72/H Reduced bouts of wheel running activity.Order From EMMA
C3H;C-Play78/H Potentially no entrainment response to light.Order From EMMA
C3H;C-Play79/H Poor entrainment response to light.Order From EMMA
C3H;C-Play81/H Long circadian period & poor entrainment responseOrder From EMMA
C3H;C-Play82/H This mutation was identified in a circadian rhythm screen. It shows reduced bouts of wheel-running activity.Order From EMMA
Plcg2<tm>-383/Bcl2-3
6Tg
Plcg2 8B cell dysfunction. Homozygotes are infertile.Order From EMMA
ple Pale.Order
C3H101H-Plp1<jp-rsh>
/H
Plp1<jp-rsh> XShivering/shaking of hind quarters.Order
GENA300 Late onset deafnessOrder From EMMA
POMC-Cre Order
Pomc-cre Z/EG Order
B6;129P2-Prep<tm1Dge
n>/H
Prep 10NoneOrder From EMMA
129P2/OlaHsd-Prnp/Pr
nd<tm1Dwm>/H
Prnp/Prnd<tm1Dwm> 2No phenotype in female mice. Male homozygotes are sterile.Order
Prnp<a(108L_189V)>
(DD)
No phenotypeOrder
Pro-Cre None.Order From EMMA
PrP Chicken-repeats Prnp<tm1Cwe> 2The octameric repeat region of the mouse prion protein was replaced with the hexameric repeat region from the domestic chicken. The mice express mouse PrP at wild-type levels with correct membrane location and orientation but have an altered metal binding region. The mice have been generated to get a better understanding of prion diseases such as CJD in humans.Order From EMMA
Ps Tyrp1<b> UNSyndactyly, extra digit, webbing of soft tissue on feet.Order
a<e> UN
PT Tyr<c-ch> 7Order
Ednrb<s> 14
Myo5a<d> 9
Tyrp1<b> 4
Bmp5<se> 9
Oca2<p> 7
PTP/H Myo5a<d> 9Order
Tyrp1<b> 4
Gpi1<a> 7
Tyr<c-ch> 7
Hbb<s> 7
Bmp5<se> 9
Ednrb<s> 14
a 2
Oca2<p> 7
Car<2b> UN
Pgm1<b> UN
Hba<f> UN
Es3<b> UN
B6;129-Ptprc<tm1Holm
>/H
Ptprc<tm1Holm> 1Defective lymphocyte development, more severe in T lineage, severe combined immunodeficiency.Order From EMMA
C3H101H-Wnt7a<px>/H Wnt7a<px> 6Sterility. Skeletal abnormalities, mainly forelimb abnormalities. Postaxial hemimelia, recessive. The forelimbs are regularly affected. There may be absence of digits 5, 4, and 3, & reduction or absence of the ulna. There is always a large oval foramen in the scapula. The hindlimbs are usually normal, but digit 5 may be absent, and occasionally the fibula is reduced. Mice with severally affected limbs tend to have an extra pair of ribs and a slight reduction in number of presacral vertebrae. Both sexes are sterile and show anomalies of the Mullerian ducts, including a partly or wholly double vagina and uncoiled oviducts in the female, and peristent Mullerian ducts in the male. Order From EMMA
Qk<qk> Qk<qk> 17Homozygotes shake and tremble when walking. Males sterile. Order
Quaver Tremors.Order
STOCK Rb(4.6)2Bnr-Rb
(4.15)4Rma-Rb(6.15)1Ald-Adamts20<bt>/H
Adamts20<bt> 15Order
STOCK Rb(4.6)2Bnr-Rb
(4.15)4Rma-Rb(6.15)1Ald-Tyrp1<B-lt>Adamts20<bt>/H
Adamts20<bt> 15Order
Tyrp1<B-lt> 4
STOCK Rb(2.8)6Rma-Rb
(6.15)1Ald-Rb(9.19)163H/H
Order
STOCK Rb(1.15)2Ct Rb
(2.18)6Rma Rb(6.13)3Rma Rb(11.16)2H/H
Order
rag1<tm1ES> Rag1 2Order
C3H;C-Rasgrf1<enu2H>
/H
Rasgrf1<enu2H> 9Small.Order From EMMA
STOCK Rb(1.10)10Bnr Order
Rb(1.15)2Ct ln Order
STOCK Rb(1.2)5H Order
STOCK Rb(1.3)1Bnr Order
STOCK Rb(10.11)8Bnr Heterozygous females give low frequencies of aneuploid fetusesOrder
STOCK Rb(11.13)4Bnr Testis weight reduced in both homozygotes and heterozygotes.Order
STOCK Rb(11.16)2H Order
C3H101H-Rb(12.13)3Ct Order
STOCK Rb(16.17)7Bnr Reduced testis weight in homozygotes.Order
STOCK Rb(16.19)1Bu/H Order
STOCK Rb(2.17)11Rma Order
STOCK Rb(2.17)4H Order
STOCK Rb(2.18)6Rma Order
C3H101H-Rb(4.14)8H Order
STOCK Rb(4.15)4Rma Order
C3H101H-Rb(4.16)10H Order
STOCK Rb(4.18)3H Order
STOCK Rb(4.6)2Bnr Order
Rb(4.6)2Bnr, Rb(9.14
)6Bnr
Bmp5<se> 9Order
Tyrp1<b> 4
Tgfa<wa1> 6
Myo5a<d> 9
Ednrb<s> 14
STOCK Rb(5.15)3Bnr/H Order
STOCK Rb(5.19)1Wh Order
STOCK Rb(6.13)1H Order
C3H101H-Rb(6.13)3Rma Order
STOCK Rb(6.15)1Ald Order
C3H101H-Rb(8.12)5Bnr testis weight are reduced in both homozygotes and heterozygotes and the sperm count for the former is significantly lowerOrder
Rb(8.19)1Ct Order
STOCK Rb(9.14)6Bnr Testis weights are reduced in both homozygotes and heterozygotes and sperm count compared to control males was approximately halved in the former.Order
STOCK Rb(9.19)163H Order
C3H101H-Rb(X.12)7H Heterozygous females are fertile but hemizygous males are sterileOrder
STOCK Rb(X.2)2Ad Order
STOCK Rb(X.9)6H Order
C3H;C-Rky/H Rky UNAt 10 weeks of age, pups show a swim phenotype described as rocky, leaning and jerky. By 18 weeks of age mice develop a head-bobbing/circling cage phenotype. Order From EMMA
REC/9 Weak limb grasp, belly spot.Order From EMMA
RECB/13 Single fetus observed with severe neural tube defect; possibly polygenic defectOrder From EMMA
C3H.Cg-Tulp3<hhkr>/H Tulp3<hhkr> 6Homozygotes have spina bifida and oedema, and die at birth.Order
Steap<Fred> Steap3<fred> 1Abnormalities in red blood cell size and shape.Order From EMMA
Redeye Homozygous mutant mice exhibit a range of eye defects including pale retinas, vascular defects & white structures present in the eye.Order
RegIII Beta knockout
noneOrder From EMMA
STOCK Mitf<Rorp>/H Mitf<Rorp> 6Dilute coat/ear/tail colour. Heterozygotes have pigment dilution, while homozygotes lack coat pigment, but retain eye(iris) pigment and do not have small eyes.Order From EMMA
STOCK Rvm/H Rvm 14Retinal vascular abnormalities.Order From EMMA
STOCK Rwhs/H Rwhs 11Retinal white spots. In heterozygotes, white spots appear on the retina from one month of age. They do not seem to reduce vision. Order From EMMA
B6;129P2-Rgs5<tm1Dge
n>/H
Rgs5<tm1Dgen> 1No visible phenotype.Order From EMMA
C3H101H-Ri/H Ringed.Order
Ricky Order
RIII/Dk Prn-i<n> UNOrder
RKS-XI No overt phenotype. Believed to be a silent mutation of Pkd111. Order
STOCK Rn/H Rn 14Rn heterozygotes have white or partly pigmented hairs throughout coat. Homozygotes are lighter than heterozygotes and are viable and fertileOrder
STOCK Rn<fkl> Rn<fkl> 14freckledOrder
B6NDen;B6N-Rnf7<tm1a
(EUCOMM)Wtsi>/H
Rnf7<tm1a(EUCOMM)Wts
i>
9Full description available in Europhenome Order From EMMA
C3H;C-Aff1<Rob>/H Aff1<Rob> 5Robotic and jerky gait. Heterozygotes exhibit small size, ataxia, adult-onset Purkinje cell loss, cataracts, reduced survival, and low fertility.Order From EMMA
ROHi Long term growth selected mouse line.Order
ROLi Long term growth selected lines.Order
C3H101H-rst/H rst UNrosetteOrder
C3H101H-Hps5<ru2> Hps5<ru2> 7ruby-eyeOrder
C3H101H-Rw/H Rw 5Rw (rump-white) is homozygote lethal. Heterozygotes have white hindlegs and tails and white fur on the posterior part of the abdomen. Order From EMMA
Rw,Kit<W-bd> Kit<W-bd> 5No pigment in rump areaOrder
Kit<W-v> 5
Rw 5
S1.2DEL Loss of Igf2 imprinting.Order From EMMA
S1.2NEO Intra-uterine growth restriction (paternal transmission).Order From EMMA
sa mu Muted<mu> 13sa: silky coat with a high sheen, mu/mu have fur of a muted brown colour.Order
Foxq1<sa> 13
sa mu pe Foxq1<sa> 13satin, muted, pearl stock.Order
Muted<mu> 13
Ap3b1<pe-H> UN
SAA2 None. Order From EMMA
C3H;C-Sagg/H Sagg 1Heterozygotes have loose skin.Order From EMMA
C57BL/6Apb-Rc3h1<san
>/Apb
Rc3h1<san> 1Autoimmune disease, ANA, lymphadenopathy, splenomegaly, hyper IgG, SLE.Order From EMMA
SB1 Reduced hearing by clickbox.Order
SB2/1 Reduced hearingOrder From EMMA
C3H101H-Sby<2H>/H Curly whiskers/absent at birth. Sporadic lack of fur growth.Some growth retardation from birthOrder From EMMA
C3H101H-scb/H scb 8Scabby.Order
STOCK Scr/H Scr 6Scruffy.Order
B6;129P2-Scube3<tm1D
gen>/H
Scube3 17No visible phenotype.Order From EMMA
SCW Severe immunodeficiency.Order
STOCK Sd/H Sd 2Urogenital abnormalitiesOrder
SDL Myo5a<d-l> 9Dilute coat. The colour of d<l>/ d<l> is identical to that of d/d but the mice develop a severe neuro-muscular disorder characterised by convulsions and opisthotonas (arching upwards of the head and tail) and they die at about 3 weeks.Order
Bmp5<se> 9
Myo5a<d> 9
C3H;C-Sbc/H Sbc 16Identified in circadian rhythm screen. These mice change their period length from normal to long after a light pulse is given at CT16 (circadian time).Order From EMMA
C3H;C-Heph<Sla>/H Heph<Sla> XHeterozygous females have striped coats. Males are small and pale at birth and most die within 1 week of birth. Females are classed at 8 days of age. Sla is an X linked dominant and classed as a harmful mutant due to lethality of males.Order From EMMA
C3H101H-Pax6<Sey-3H> Pax6<Sey-3H> 2Small at birth and weaning with small eyes, white feet and sometimes a belly spotOrder
C3H101H-Pax6<Sey-H> Pax6<Sey-H> 2Small-eye.Order From EMMA
129-Foxp3<sf>/H Foxp3<sf> Xscurfy, scaliness first of tail later other parts of body, skin tight, eyelids open late, males usually die before / shortly after weaning, survivors small & sterile, small abdominal tetsis & lack scrotum. Occasional sf females are X/O resemble sf males. Similar human disease: Ichthyosis and Male HypogonadismOrder From EMMA
C3H;C-Sfrp2<C50F>/H Sfrp2<C50F> 3Normal.Order
B6J.Cg-Sfrp2<l153N>/
H
Sfrp2<I153N> 3Order
B6J.Cg-Sfrp2<l153N>/
H
No Overt Phenotype. Full description available from Europhenome Order
B6.Cg-Sfrp2<C50F>/H Sfrp2<C50F> 3Order
B6.Cg-Sfrp5<Q27STOP>
/H
Sfrp5<Q27stop> 19Order
Sgd Small at birth and weaning, progressive hairless (from 3 weeks of age) with accompanying thickinening of the skinOrder
Shby/+ Shabby. Patchy coat, tail rough. Cyclic epilation.Order
Sherbert Order
C3H.Cg-Sfl/H Sfl 2Identified in circadian rhythm screen. Mice carrying this mutation have no phase shifting response to a light pulse given at CT16. Order From EMMA
C3H.Cg-Sci/H Sci 8Identified in circadian rhythm screen. Short circadian period of wheel-running activity (22.5 hrs rather than 23.5 hrs). Wheel running activity is about 10% of control animals.Order From EMMA
Shp2CS x DO11.10 L1 Characterisation of the phenotype is still in progress, but the line displays amplified cytokine secretion in response to antigenic challengeOrder
Shp2CS x DO11.10 L5 Characterisation of the phenotype is still in progress, but the line displays amplified cytokine secretion in response to antigenic challengeOrder
Shp2CSxB10.BR Line 1 Characterisation of phenotype still in progress but line displays defective primary immune responses to T-dependent antigen and amplified cytokine secretion in response to antgenic challenge.Order From EMMA
C3H;C-Sic/H Sic 7Sickly . Classed as harmful. Heterozygotes are small and sickly. Mutation has not been tested for homozygosity. The Sickly mice are marginally smaller than wildtype sibs at birth and dramatically smaller (<50%) at weaning. The nature of this growth defect has yet to be investigated. Heterozygous mice are also prone to infection.Order From EMMA
SIG (Position Testin
g Stock chr.6)
Grid2<Lc> 6Mitf<Mi-wh> is semidominant. The homozygotes are viable white mice, the eyes are pink at birth. The heterozygotes have light sandy coats and belly spots. Grid2<Lc> is homozygous lethal, the heterozygotes have swaying hindquarters and jerky up and down movement. Sig is homozygous lethal, the heterozygotes are blind, the eyes are open at birth, some exhibit hydrocephaly.Order
Mitf<Mi-wh> 6
Sig 6
C3H101H-skimp/H skimp 7Order
C3H;C-Jag1<Slalom>/H Jag1<Slalom> 2These mice exhibit head weaving and shaking behaviour.Order From EMMA
Slc38a4<tm2Kel>/Delt
aCG1A
None, a minor effect on term weight.Order From EMMA
B6;129P2-Slc7a10<tm1
Dgen>/H
Slc7a10<tm1Dgen> 7No visible phenotype.Order From EMMA
C3H101H-Pou3f4<Slf>/
H
Pou3f4<Slf> Xsex-linked fidgetOrder
Slip Order
C3H.Cg-Sgh/H Sgh 4Mice carrying this mutation demonstrate a low endurance of wheel running activity which is reduced to about 10% of control values.Order From EMMA
Smad 2 D2 NoneOrder From EMMA
Smad 2 FL Smad2 18Embryonic lethal at day 8.5 dpc.Order From EMMA
Smad 2 SF Smad2 18Homozygous lethal at day 8.5.Order From EMMA
Smad 2 T3 Smad2 18Approx 50% of homozygotes are embryonic lethal at 15d, remainder are viable as adults.Order From EMMA
Smad8 conditional NoneOrder From EMMA
Smad8 LacZ Smad9<tm1Rob> 3NoneOrder From EMMA
C3H101H-Sme/H Sme UNReduction in size of pinna and often irregular in shapeOrder
SMN E134K Transgenic None.Order From EMMA
SMN2 low Tg(SMN2)89Ahmb UNMice that are homozygous for the targeted mutant Smn1 allele and carry the SMN2 transgene exhibit symptoms and neuropathology similar to patients afflicted with type I proximal spinal muscular atrophy (SMA) but die at P6. (See Monani 2000 HMG 9 333-339). Mice homozygous for Smn1-/-, in the absence of SMN2 would die before birth. Heterozygotes for the knockout show no phenotype.Order
Smn1<tm1Msd> 13
SMNDelta5 None.Order From EMMA
SMNDelta5-SMN2Low Rescues post natal lethality of SMN2 low strain Order From EMMA
SOCS-6 Socs6<tm1Dlk> 1810% increased body weight & increased insulin sensitvity.Order From EMMA
sooty foot soo 2Order
Sox4<m91Ark> Sox4<m91Ark> 13Embryonically lethal.Order From EMMA
GENA203 Polydactyly.Order From EMMA
C3H.Cg-Celsr1<Scy>/H Celsr1<Scy> 15Mice carrying this mutation exhibit circling behaviour.Order From EMMA
C57BL-Spnb4<qv-3J>/H Spnb4<qv-3J> 7Heterozygotes apppear normal, homozygotes have locomotor instability, pronounced quivering, deafness. Homozygote males are sterile.Order
Ssm shaker smallOrder
Ssy small syndactylyOrder
C3H101H-Nsdhl<Str-1H
>/H
Nsdhl<Str-1H> XstriatedOrder From EMMA
C3H101H-Nsdhl<Str-2H Nsdhl<Str-2H> XstriatedOrder
C3H;C-Strg/H Strg XStriped and greasy.Order
STOCK Sts<->/H Order
STOCK Myo6<sv>/H Myo6<sv> 9Order
Svc (GENA 291) Col4a1<Svc> 8Small with vacuolar cataractOrder
C3H101H-Dync1h1<Swl>
/H
Dync1h1<Swl> 12Sprawling, abnormal posture and locomotion from defective position sense mainly affecting hind limbs, myelination deficient, deficiency of sensory receptors, spindles virtually absent from hind limbs.Order From EMMA
SWR/Ola Hsd Tyr<c> 7Order
Sxr Eda<Ta-33H> XOrder
C3H101H-Tp(Y)1Ct<Sxr
-b>/H
Tp(Y)1Ct<Sxr-b> YOrder
sy<a> Shaker with syndactylism Albany. Order
B6;129-Sycn<tm1Rja>/
H
Sycn<tm1Rja> 7Pancreatic secretion compromised.Order From EMMA
C3H101H-T(10;13)199H Order
C3H101H-T(10;18)18H Order
T(10;18)18Hdl Order
C3H101H-T(11;13)41Ad Order
T(11;13)41Ad cross 2 Order
C3H101H-T(11;13)56H Order
C3H101H-T(11;19)42H Order
C3H101H-T(13;14)69H Order
T(14;15)6Ca hr Order
CBA/H-T(14;15)6Ca Order
T(1;10)73H Order
C3H101H-T(1;12)52H Order
STOCK T(1;13)70H Order
JUN-T(1;2)5Ca Order
C3H101H-T(1;4)71H Order
C3H101H-T(1;6)42Ad Order
C3H101H-T(1;7)49H Order
C3H101H-T(1;8)63H Order
C3H101H-T(2;11)30H Order
T(2;11)30H - cross 4 Order
C3H101H-T(2;14)48H Order
C3H101H-T(2;15)45Ad/
H
Order
STOCK-T(2;16)28H Order
STOCK-T(2;19)68H Order
C3H101H-T(2;3)24H Order
C3H101H-T(2;4)13H Order
C3H101H-T(2;4)1Ca Order
T(2;4)1Go Order
STOCK T(2;4)1Sn Order
T(2;5)72H Order
C3H101H-T(2;6)7Ca Order
T(2;8)26H Order
STOCK T(2;8)2Wa/H Order From EMMA
T(2;9)11H Order
C3H101H-T(3;10)61H Order
C3H101H-T(3;12)58H Order
C3H101H-T(3;19)25Ad Order
C3H101H-T(3;8)56Ad Order
C3H101H-T(4;10)Hsc76
H/H
Head shaker, circling.Order
C3H101H-T(4;12)47H Order
C3H101H-T(4;5)46H Order
C3H101H-T(4;6)77H/H Homozygotes are sometimes infertile.Order
C3H101H-T(4;6)77H-Mi
tf<Mi-wh>/H
Mitf<Mi-wh> 6Homozygotes sometimes infertile.Order
T(4;8s)36H Order
STOCK T(4;9)45H Order
C3H101H-T(5;11)57H Semi-sterile.Order
C3H101H-T(5;12)31H Order
STOCK T(5;13)264Ca Order
C3H101H-T(5;7)30Ad Order
C3H101H-T(6;12)32H Order
C3H101H-T(6;13)6Ad Order
T(6;14)39H Order
STOCK T(6;7)51H Order
C3H101H-T(6;8)2Ad Order
STOCK T(7;11)40Ad/H Order
STOCK T(7;11)65H Reciprocal translocationOrder
C3H101H-T(7;13)7Ad Order
C3H101H-T(7;15)9H Heterozygotes are semi-sterile.Order
C3H101H-T(7;16)67H Order
STOCK T(7;19)145H Male sterile.Order From EMMA
C3H101H-T(9;10)62H Order
STOCK T(9;17)138Ca Order
C3H101H-T(In1;5)44H Order
C3H101H-T(X;11)38H Order
C3H101H-T(X;4)37H Order
STOCK T(X;7)3Neu Order
C57BL/6Apb-Lcp2<twm>
/Apb
Lcp2<twm> 11Few naïve CD4+ and CD8+ T cells, autoimmunity, 5fold decrease in DP Tcells. Defects in positive selection & reduced negative thymocyte selection, hypergammaglobulinemia and hyper-IgE.Order From EMMA
STOCK T<21H>/H T<21H> 17Effects like brachyuryOrder From EMMA
C3H101H-T<22H> T<22H> 17T<22H>/t<6> males have enhanced transmission ratioOrder
C3H101H-T<24H>/H T<24H> UNBrachyury.Order
C3H101H-T<25H>/H T<25H> UNbrachyury, sometimes slightly small mice with shortened, kinky tails. Males breed satisfactorily but females show impaired transmission producing few T<25H> offspring which have low viability. Homozygote presumed lethal.Order
T<26H> T<26H> UNbrachyuryOrder
C3H101H-T<29H> T<29H> 17Order
C3H101H-T<30H> T<30H> 17Order
C3H101H-T<31H> T<31H> 17Short tailsOrder
C3H101H-T<32H>/H T<32H> 17Heterozygotes - short tail, homozygotes - lethal.Order
C3H101H-T<33H> T<33H> 17short tails. Homozygotes lethal.Order
C3H101H-T<34H> T<34H> 17Heterozygotes - short tail, Homozygotes - lethal.Order
C3H101H-T<36H> T<36H> 17Short tailsOrder
STOCK t<6>/H t<6> 17Taillessness with TOrder
C3H101H-T<c-2H> T<c-2H> 17taillessOrder
C3H101H-T<c>/H T<c> 17T<c>/+ and T<c>/t<h7> tailless. T<c>/T<c> lethal, like T/T but more severely affectedOrder From EMMA
C3H101H-t<h17> t<h17> 17Order
t<h18> t<h2> t<h18> 17Gives tailless with T. Homozygotes for t<h18> are lethal. t<h18> carries distal distortion D2 and t<h2> carries responder R.Order
t<h2> 17
STOCK t<h20> t<h20> 17Order
STOCK t<h44> t<h44> 17T/t<h44> taillessOrder
STOCK t<h49> t<h49> 17Order
STOCK t<h50> t<h50> 17Order
STOCK t<h51> t<h51> 17Order
t<h51>t<h18> t<h18> 17Lethal when homozygous.Order
t<h51> 17
t<lowH> 17
C3H101H-t<h57> t<h57> UNOrder
STOCK t<h7> t<h7> 17Order
t<h7m2> t<h7m2> UNtailess with TOrder
t<h7m> t<h7m> UNTailless with T, homozygous viable.Order
T<21H> UN
STOCK T<hp>/H T<hp> 17Order
t<hr15> t<hr15> UNTailessOrder
t<hr1> t<hr1> UNTaillessOrder
t<hr4> t<hr4> UNTaillessOrder
t<low2H> t<low2H> UNOrder
t<low3H> t<low3H> 17Order
STOCK t<lowH> t<lowH> 17Order
t<low2H> UN
STOCK t<lub2>/H t<Lub2> 17Order
STOCK t<s6>/H t<s6> 17Order
STOCK t<w32>/H t<w32> 17Order
C3H101H-t<w32m>/H t<w32m> UNOrder
t<x507> t<x507> UNTailessOrder
tf<t> UN
Ta<10H> Eda<Ta-10H> UNTabby.Order
C3H101H-Eda<Ta-23H> Eda<Ta-23H> XOrder
Ta<23H> Xce<c> Pgk1<
a>
Eda<Ta-23H> XOrder
Xic<c> X
Pgk1<a> UN
C3H101H-Eda<Ta-25H> Eda<Ta-25H> XtabbyOrder
C3H101H-Eda<Ta-26H> Eda<Ta-26H> Xtabby, has a hairy tailOrder
C3H101H-Eda<Ta-27H>/
H
Eda<Ta-27H> UNTabby. The males have hairless tails.Order
C3H101H-Ta<28H>/H Eda<Ta-28H> UNTabby. The males have hairless tails.Order
C3H101H-Eda<Ta-29H> Eda<Ta-29H> Xtabby, males have hairless tailsOrder
C3H101H-Eda<Ta-30H> Eda<Ta-30H> XtabbyOrder
C3H101H-Eda<Ta-32H> Eda<Ta-32H> XtabbyOrder
C3H101H-Eda<Ta-33H> Eda<Ta-33H> Xtabby, hairy tail and the teeth do not need cuttingOrder
C3H101H-Ta<35H>/H Eda<Ta-35H> UNTabby, males have hairless tails and are bald behind the ears.Order
C3H101H-Eda<Ta-36H>/
H
Eda<Ta-36H> UNTabby.Order
Ta<37H> Eda<Ta-37H> UNtabbyOrder
C3H101H-Eda<Ta-38H>/
H
Eda<Ta-38H> UNTabby.Order
C3H101H-Eda<Ta-39H>/
H
Eda<Ta-39H> UNTabby.Order
Ta<44H> TA<Fa> like ie heterozygous females-striped, Hemizygous males-weak teeth, no guard hairs, bald tails, very little hair behind ears.Order From EMMA
C3H101H-Tal/H Tal 14Heterozygotes cannot easily be identified at birth but can be classified at weaning. The feet are held in an abnormal position, there is soft tissue syndactylism involving digits 2,3, and to a lesser degree 4, and there is often overgrowth and twisting of the toenails. The forefeet are less obviously affected than the hindfeet. Homozygotes are more severely affected with extreme shortening of the phalanges and significant reduction to the metatarsals. The tail shows a kinking to form a hook near the tip.Order
TAS16 Curly tailOrder From EMMA
TAS2 Belly spot, head spot, white feet (variable).Order From EMMA
TAS4 Multiple white spotting over entire bodyOrder From EMMA
TAS6 Belly spot, white feet, head spotOrder From EMMA
tcl<6> tcl<6> UNOrder
Tcx Striped coats in females,greasy coat in males.Order
C3H101H-Ebp<Td>/H Ebp<Td> XTattered.Order From EMMA
tde Grxcr1<pi-tde> 5insertional mutation Tasmanian devilOrder
TERB-54 Possible modifier of Huntingdon's disease. Affected mice present with gait problems.Order
TERB-56 Possible modifier of Huntingdon's Disease. Affected mice have intermittent paralysis in one hind leg. Culled at 12 weeks Order
TERB-57 Order
C3H101H-Tesa/H Tesa UNMice carrying this mutation are deaf, have short tails and exhibit circling behaviour.Order From EMMA
TESOD-20 This stock is a model for ALS (Amyotrophic Lateral Sclerosis), a progressive, usually fatal neurogenerative disease caused by the degeneration of motor neurons. They are carrying a modifier ENU induced mutation that makes their whole phenotype more severe. Mice were dying at around 30-35 weeks of age with a severe ALS phenotype so therefore they are usually humanely killed once they get one hind limb paralysed.Order
Tesod-36 Order
TESOD-37 Order
TFH Order
TFH/H T 17Shorter tail, blunt.Order From EMMA
tf 17
TFL Order
C3H101H-Cacna1a<tg>/
H
Cacna1a<tg> 8Tottering phenotype. Homozygotes have wobbly gait from 3-4 weeks and intermittant seizures. Heterozygotes appear normal.Order
Tg(-214VpreB1-huCD12
2)F133Lmb
No known effectsOrder From EMMA
Tg(5'lambda 5-huCD25
)82Lmb
No known effectsOrder
Tg(CMV-tetO-CFTR)TC3
5CH
NoneOrder From EMMA
Tg(Leftb-cre)1Hmd Tg(Leftb-cre)1Hmd UNOrder
Tg(Nmnat1) 7104Cole None.Order
B6J;CBA-Tg(RP1-309F2
0)48Kel
Order From EMMA
Tg(RP21-340H11)29Kel Mild hyperglycaemia in neonates, mildly impaired glucose tolerance post weaning.Order From EMMA
CBB6-Tg(runx1/MTG8)I
CH10Fc/H
Order
CBB6-Tg(runx1/MTG8)I
CH11Fc/H
Order
CBB6-Tg(runx1/MTG8)I
CH12Fc/H
Order
CBB6-Tg(runx1/MTG8)I
CH7Fc/H
Order
CBB6-Tg(runx1/MTG8)I
CH8Fc/H
Order
CBB6-Tg(runx1/MTG8)I
CH9Fc/H
Order
Tg(Sox2-cre)1Amc Tg(Sox2-cre)1Amc UNOrder
Tg(T-cre)1Lwd Tg(T-cre)1Lwd UNOrder
Tg(TH1-TauV337m)T39 Tg(Thy1-MAPT*V337M)1
Godt
UNDevelopment of abnormal tau phosphorylation & aggregation within the brain, as seen in Alzheimer's & other tauopathies. Highly discrete & specific age-dependent cognitive changes including memory impairment & impaired impulse control.Order
Tg(Wnt1-cre)11Rth Tg(Wnt1-cre)11Rth UNOrder
129-Tgfbr2<tm1Roes>/
RoesH
Tgfbr2<tm1Roes> 9Order From EMMA
STOCK Epo<Tg(SV40T/E
po)134.3LCPjr>/H
Epo<Tg(SV40T/Epo)134
.3LCPjr>
UNHomozygotes have incomplete epo deficiency and are anaemic.Order From EMMA
Tg(bTGTRfs)1Vkc Order
TgN(CEB1GEN)-G NoneOrder
TgN(CEB1GEN)-H NoneOrder
TgN(CEB1GEN)-I NoneOrder
B6C3-Tg(HD82Gln)81Db
o/H
Tg(HD82Gln)81Dbo UNOnset of abnormal gait and tremors at 3 months. Fail to gain weight from 2 months.Order
B6CB-Tg(PMP22)C1Clh Tg(PMP22)C1Clh UNOrder
B6;CB-Tg(PMP22)C22Cl
h/H
Tg(PMP22)C22Clh UNShaking & unsteady gait.Order From EMMA
B6CB-TgN(PMP22)C58Cl
h
Order
B6CB-Tg(PMP22)C61Clh Order
B6CB-Tg(PMP22)JP18Cl
h
Order
(B6xCB)F2-Tg(PMP22)M
Y41Clh
Tg(Pmp22)My41Clh UNShaky & unsteady gait.Order
B6CB-Tg(pUHG16)JU2Cl
h
NoneOrder
B6CB-Tg(yCFTR)A10Clh
/H
NoneOrder
B6CB-Tg(yCFTR)T30Clh
/H
Order
B6CB-Tg(yCFTR)T57Clh
/H
None.Order
TgNmnat1 line 881 None.Order
C57BL/6S-Hnrpll<thdr
>/Apb
Hnrpll<thdr> 17A marked reduction in the no. of peripheral T cells, especially naïve CD4 & CD8 cells, and poor survival of thunder T cells upon adoptive transfer. The T cells are hyperactivated.Order From EMMA
Tiffany Mice exhibit eye defects. Sections of the lens diffract light differently.Order
C57BL/6Apb-Lig4<tiny
>/Apb
Lig4<tiny> 8Small in size, no CD8 cells or B cells, TCR Tg appears to rescue T cells. Similar to human SCID.Order From EMMA
Tis11b<tm1mt> Day 9 embryonic lethalOrder
C3H101H-Tks/H Tks 9tail kinksOrder
B6;129P2-Tln1<tm1Cri
t>/CritH
Tln1<tm1Crit> 4Order From EMMA
129/SvEv-Tln1<tm1Cri
t>/CritH
Tln1<tm1Crit> 4Order
Tlss Thymo lymph sarcoma susceptibility.Order
TM/45 Abnormal response to Intraperitoneal Glucose Tolerance Test at 24 weeks of age.Order From EMMA
TM/47 Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes. Order From EMMA
TM/58 These mice have an abnormal walking posture, appearing as though the hips are fused. Histological examination shows this to be a muscular phenotype.Order From EMMA
TM/59 Abnormal response to Intraperitoneal Glucose Tolerance Test at 12 weeks of age. Fasting hyperinsulinaemia at 16 weeks. Mice are significantly heavier than wildtype at 12 and 16 weeks of age.Order From EMMA
TM/60 Abnormal response to Intraperitoneal Glucose Tolerance Test at 12 weeks of age. Abnormal IPGTT and fasting hyperinsulinaemia at 16 weeks. Mice are significantly heavier than wildtype at 12 and 16 weeks of age.Order From EMMA
TM13 Head bobbingOrder From EMMA
TM2 Behavioural/low anxiety phenotypeOrder
TM4 High T60 in intraperitoneal glucose tolerance tests.Order From EMMA
B6;129P2-Tmem67<tm1D
gen>/H
Tmem67 4No visible phenotypeOrder From EMMA
TMR/10 Mutant mice fail to bury marbles in sawdust when left for a period of 30 minutes.Order From EMMA
Tmsb4x<tm1Tnr> Tmsb4x XB-cell defect.Order From EMMA
To Cat5<To2> 10Order
C3H101H-Lim2<To3>/H Lim2<To3> 7Total opacity, dominant cataract.Order From EMMA
B6;129P2-Tpcn1<tm1Dg
en>/H
Tpcn1 5No visible phenotype. IVF/1772.1k - short tail, IVF/1772.1m- tail kink.Order From EMMA
TPL Order
Tpm1<tm1aWtsi> Tpm1 9None.Order From EMMA
C3H.Cg-Pmp22<Tr-1H>/
H
Pmp22<Tr-1H> 11Tremors with seizures. Tremors, muscle weakness.Order From EMMA
C3H;C-Pmp22<Tr-2H>/H Pmp22<Tr-2H> 11Tremors, muscle weakness.Order From EMMA
Trembly Muscular dystrophy, small size, muscle wasting.Order
C3H101H-Trf<bm>/H Trf<bm> UNOrder
B6;129P2-Trpc4<tm1Dg
en>/H
Trpc4 3No visible phenotype.Order From EMMA
B6;129P2-Trpc6<tm1Dg
en>/H
Trpc6 9No visible phenotype.Order From EMMA
C3H101H-Tsk2/H Tsk2 1Heterozygotes can be recognised at 1 to 2 weeks of age by a tightness of the skin across the shoulders when picked up. The mice are fully viable and fertile. Order From EMMA
Tyr<c-37Hch> Tyr<c-37Hch> UN(hair - colour, eye - colour) chinchillaOrder
Tyr<c-38Hch Tyr<c-38Hch> UN(hair - colour, eye - colour) chinchillaOrder
C3H101H-Tyr<c-40H>/H a 2(hair - colour, eye - colour, behaviour - sight) albinoOrder
Tyr<c-40H UN
Tyr<c-42H> Tyr<c-ch> 7(hair - colour, eye - colour, behaviour - sight) albino.Order
Tyr<c-42H> UN
Tyr<c-43H> Tyr<c-ch> 7(hair - colour, eye - colour, behaviour - sight) albinoOrder
Tyr<c-43H> UN
C3H101H-Tyr<c-44H> Tyr<c-44H> 7(hair - colour, eye - colour, behaviour - sight) albinoOrder
C3H101H-Tyr<c-45H> Tyr<c-45H> 7(hair - colour, eye - colour, behaviour - sight) albinoOrder
C3H101H-Tyr<c-46H> Tyr<c-46H> 7(hair - colour, eye - colour, behaviour - sight) albinoOrder
C3H101H-Tyr<c-47H>/H Tyr<c-47H> UN(hair - colour, eye - colour, behaviour - sight) albinoOrder
Tyr<c-49Hch> Tyr<c-49Hch> UN(hair - colour, eye - colour, behaviour - sight) albinoOrder
Tyr<c-50H> Tyr<c-50H> UN(hair - colour, eye - colour, behaviour - sight) albinoOrder
Tyr<c-51H> Tyr<c-51H> UN(hair - colour, eye - colour, behaviour - sight) albinoOrder
Tyr<c-54Hch> Tyr<c-54Hch> UN(hair - colour, eye - colour) chinchillaOrder
Tyr<c-55H> Tyr<c-ch> 7(hair - colour, eye - colour, behaviour - sight) albinoOrder
Tyr<c-55H> UN
C3H101H-Tyr<c-em>/H Tyr<c-em> 7(hair - colour, eye - colour) chinchilla extreme mottled. Extreme dilution of coat.Order From EMMA
C3H101H-Tyr<c-m>/H Tyr<c-m> 7(hair - colour, eye - colour) chinchilla mottledOrder
C3H101H-Tyr<c-r>/H Tyr<c-r> 7(hair - colour, eye - colour) ruby-eyedOrder
C3H101H-Tyrp1<b-55H>
/H
Tyrp1<b-55H> UN(hair - colour) brown.Order
C3H101H-Tyrp1<b-65H>
/H
Tyrp1<b-65H> UN(hair - colour) brownOrder
C58-Tyrp1<B-lt>/H Tyrp1<B-lt> 4(hair - colour) heterozygotes have light underfur, homozygotes almost white hair except tipsOrder
C3H101H-Ufde/H Affected individuals have one or both ears low set and reduced in size.Order
C3H101H-Lnp<Ul>/H Lnp<Ul> 2Ulnaless.Order
UMLC-TM/12 Statistically lowered body weight & plasma levels of glucose after an overnight fast at 12 & 16 wks of age. DEXA at 14 wks: decreased body weight, lean & total tissue, BMD & BMC.Order
UMLC-TM/6 Statistically elevated body weight & plasma levels of glucose, leptin & adiponeptin after an overnight fast at 12 & 16 wks of age. In addition elevated levels of insulin at 16wks of age. DEXA at 14wks: increased fat mass & % fat.Order
C57BL/6Apb-Card11<un
m>/Apb
Card11<unm> 5The mice make poor antibody responses, and as they age they develop atopic dermatitis and hyper-IgE, with red itchy ears & weepy eyes, progressing to badly eroded skin from itching.Order From EMMA
UTR/mdx (TEX) This stock contains a tetracyclin inducible utrophin transgene when crossed with MCK-tTA mice.Order From EMMA
Utrn<+/-> Utrn<+/-> UNAbnormal neuromuscular junction morhpology.Order
Utrn<-/-> Utrn<-/-> UNAbnormal neuromuscular junction morhpologyOrder
v<ALB> Cdh23<v-Alb> 10Waltzer Albany.Order From EMMA
C3H;C-Vng/H Vng 5Small. One low ear.Order From EMMA
VANIMMA Under investigation: not severely immunocompromised.Order
B6.129P2-Vnn1<tm1Pna
>/H
Vnn1<tm1Pna> 10 Order
B6.129P2-Vnn1<tm1Pna
>/H
Vnn1<tm1Pna> 10 Order
VAV-NPM/ALK Mice develop lymphoid tumours from 6 months of age.Order From EMMA
B6;129P2-Vipr1<tm1Dg
en>/H
Vipr1 9No visible phenotypeOrder From EMMA
C3H101H-Vm/H Heterozygote males have a high probability of being sterile. Visceral myopathy. Off white coat colour, intestinal problems in some animals. Males may be sterile. Older animals develop tremors. Homozygotes die soon after birth with major kidney abnormalities.Order
VM/Dk Order
STOCK Kit<W>/H Kit<W> 5Dominant white spottingOrder
B6129-Tg(Wap-cre)117
38Mam
Tg(Wap-cre)11738Mam UNThere is no abnormal phenotype. Albino, black or white bellied Agouti.Order
Ward Wines 5 Small increase in kidney size, possible late-onset cyst formation.Order
C3H;C-Egfr<Wa5>/H Egfr<Wa5> 11Small eyes, eyes open at birth, curly whiskers and coat. Heterozygotes have open eyelids and curly whiskers at birth. The first coat has a crimped appearance and subsequent coats are wavy/rough.Order From EMMA
wavy coat Mice carrying this mutation have a wavy coat.Order From EMMA
C3H;C-Whto/H Whto 7White toes. Heterozygous Whto mice display white belly spots and/or white toes. Homozygotes would appear to be embryonic lethal.Order From EMMA
STOCK Whrn<wi>/H Whrn<wi> 4Deaf, head tossing and circling. Whirler.Order From EMMA
Wnt2b No visible phenotypeOrder
C3H101H-Wnt3a<vt>/H Wnt3a<vt> 11(1) vestigial tail (2) Homozygotes have very short tails, varying form complete absence to about half normal length.Order
STOCK Wnt3a<vt>Foxq1
<sa>Muted<mu>/H
Muted<mu> 13Vestigial tail.Order
Wnt3a<vt> 11
Foxq1<sa> 13
C3H101H-Eef1a2<wst>/
H
Eef1a2<wst> 2Wasted homozygotes can be recognised at 20 days of age by tremor and uncoordinated body movements. They develop progressive paralysis and do not survive beyond 30 days. The wasted heterozygotes have normal viability. Also contains Ra. The ragged heterozygotes have thin, ragged coats. The homozygotes are almost naked and are semi-lethal.Order
C3H101H-Xic<a> Xic<a> XOrder
Xce<a> Pgk1<a> Pgk1<a> UNOrder
Xce<a> UN
Xce<b> Atp7a<Mo-blo> Xce<b> UNOrder
Atp7a<Mo-blo> UN
Xce<b> Pgk1<a> Xce<b> UNOrder
Pgk1<a> UN
Xce<b>, Ta<Fa> Xce<b> UNOrder
Xce<c> Pgk1<b> Xce<c> UNOrder
Pgk1<b> UN
Xla Anaemia in females, seen at birth to 2 days old and may be small.Order From EMMA
XO Eda<Ta> XOrder
Atp7a<Mo-blo> X
C3H101H-Xs/H Xs 7Extra-toes spottingOrder From EMMA
Y<d-1> Order
Y<d-2> Order
Y<d-3> Order
Y<d-5> Order
Y<d-6> Order
Y<d4> Order
Y<dr1> Order
Y<dr2> Order
Y<dr3> Order
Y<dr4> Order
Y<dr5> Order
C57BL/6J-Chr Y<POS>/
H
May show XY sex reversal and hermaphroditism.Order
C3H;C-Ankrd11<Yod>/H Ankrd11<Yod> 8Craniofacial, broad face. Heterozygotes (Ankrd11<Yod>/+) have readily distinguishable craniofacial features. Further to this, abnormal bone morphology including an abnormally small growth plate, negligible chondrocyte hypertrophy and a dramatically reduced zone of woven bone formation have been detected.Order
C3H.Cg-Ankrd11<Yod>/
H
Ankrd11<Yod> 8Craniofacial, broad face. Heterozygotes (Ankrd11<Yod>/+) have readily distinguishable craniofacial features. Further to this, abnormal bone morphology including an abnormally small growth plate, negligible chondrocyte hypertrophy and a dramatically reduced zone of woven bone formation have been detected.Order From EMMA
YZ15 Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. Unlike low copy number lines, the Igf2 LacZ gene does not show appropriate reciprocal imprinting in YZ15 mice as it is expressed from both parental alleles.Order From EMMA
YZ17 Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. Deletion of the intergenic region with Cre recombinase results in partial (mesoderm specific) reactivation of Igf2 LacZ expression following maternal transmission.Order From EMMA
YZ20 Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over?expressing H19 is not fully characterised. Order From EMMA
YZ46 Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised.Order From EMMA
YZ8 Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. The imprinted H19 gene is only expressed when transmitted through the maternal germline. After paternal transmission the gene is repressed. The Igf2 LacZ gene shows appropriate reciprocal imprinted behaviour (paternal allele specific expression, maternal repression). Order From EMMA
ZA1 a<e> 2Order
Tyrp1<b> 4
Tyr<c-ch> 7
Dock7<m> 4
C3H101H-a<t>Tyrp1<b-
cH>Tyr<c-ch>/H
a<t> 2Order
Tyr<c-ch> 7
Tyrp1<b-cH> 4

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