A Portfolio of MND mouse mutants

As part of a project funded by the Motor Neurone Disease Association (MNDA) we are screening the Harwell ENU archive for mutations in genes related to motor neurone disease (MND, ALS). Strains listed below are currently stocked as sperm samples. They will be shipped as live animals/frozen embryos after In vitro fertilization (IVF) at a cost recovery price subject to a standard MRC MTA agreement. For further information, please contact Abraham Acevedo Arozena

GeneMutation Alignment
Senataxin
V44E
M401K
V1058I
K1261E
V1307A
L2137S
S2124P
Progranulin
Q47H
C227S
I330F