Title | Phenotype | Contact | |||||||||||||
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STOCK Whrn<wi>/H |
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Deaf, head tossing and circling. Whirler. | Contact | ||||||||||||
STOCK Xpo4<Gt(PT1-ATG)3EVal>/H |
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Phenotypically normal. | Contact | ||||||||||||
STOCK Yod1<tm1aNarl>/H |
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To see phenotype data (when available) visit www.mousephenotype.org Heterozygotes: males lose hair at 4 weeks of age, stated tat "recovery accompanies age". | Contact | ||||||||||||
STOCK-Rala<tm1.2Cjm>/H |
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Both floxed heterozygotes and homozygotes are healthy, fertile and have a normal life span. | Contact | ||||||||||||
STOCK-Ralb<tm1.2Cjm>/H |
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Both heterozygotes and homozygotes are fertile and have a normal life span. | Contact | ||||||||||||
STOCK-Tecta<tm4.1Gpr> |
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In Tecta<tm4.1Gpr>/<tm4.1Gpr> homozygotes the tectorial membrane is completely detached from the spiral limbus and is associated instead with the Reissner membrane. Tecta is readily detectable by immunofluorescence in the detached tectorial membrane. Heterozygotes: inner ear phenotype shows malformation of the tectorial membrane, ABR thresholds elevated by ~30 dB and an enhanced susceptibility to audiogenic seizure at low sound pressure levels. See PubMed 24363064 Legan et al Human Mol Genet 2013: Three deaf mice. | Contact | ||||||||||||
STOCK-Tg(MMTV-VEGFB*)1Sjh/SjhH |
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The offspring of hemizygous mothers, but not hemizygous fathers, die shortly after birth. The female transgenic mice have fewer blood vessels, less blood in the mammary tissue, and impaired alveolar coverage of the fat pad, and do not produce sufficient milk for nourishment of their pups. | Contact | ||||||||||||
Tardbp LCDmut (M323K) |
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Mice carry a point mutation in a gene call Tardbp (TDP43) involved in motor neurone disease and fronto-temporal dementia. | Contact | ||||||||||||
Tardbp LCDmut (M323K) |
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Mice carry a point mutation in a gene call Tardbp (TDP43) involved in motor neurone disease and fronto-temporal dementia. | Contact | ||||||||||||
Tardbp LCDmut(M323K) |
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Mice carry a point mutation in a gene call Tardbp (TDP43) involved in motor neurone disease and fronto-temporal dementia. | Contact | ||||||||||||
Tardbp RRM2mut (F210I) |
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Tardbp<Rgsc2268> mice carry a point mutation in a gene call Tardbp (TDP43) involved in motor neurone disease and fronto-temporal dementia. | Contact | ||||||||||||
Tardbp RRM2mut (F210I) |
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Tardbp<Rgsc2268> mice carry a point mutation in a gene call Tardbp (TDP43) involved in motor neurone disease and fronto-temporal dementia. | Contact | ||||||||||||
Tardbp RRM2mut (F210I) |
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Tardbp<Rgsc2268> mice carry a point mutation in a gene call Tardbp (TDP43) involved in motor neurone disease and fronto-temporal dementia. | Contact | ||||||||||||
TAS6 |
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Belly spot, white feet, head spot | Contact | ||||||||||||
TBL1XR1-Y446C-EM1-B6 |
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Contact | |||||||||||||
Tbx22<tm1Sta> |
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Heterozygotes: Males: submucous cleft palate due to reduced palatal bone formation and also display variable ankyloglossia and occasional choanal atresia. Females: normal. Homozygotes: submucous cleft palate due to reduced palatal bone formation and also display variable ankyloglossia and occasional choanal atresia. | Contact | ||||||||||||
TFH/H |
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Shorter tail, blunt. | Contact | ||||||||||||
Tg(ACTA2-TFPI/CD4/SELP)#aAdor |
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Mice express membrane tethered human TFPI-CD4 fusion protein on all alpha-SMA+ (alpha smooth muscle actin) cells. In cells with secretory granules, these will be internalised at resting state by virtue of P-selectin cytoplasmic sequence. The hTFPI (human tissue factor pathway inhibitor)inhibits tissue factor and FXa (factor Xa). | Contact | ||||||||||||
Tg(OvPrP)EF50 | Overexpression of transgenic ovine PrPC in brain and other tissues of this mouse line in order to confer increased susceptibility to TSE diseases compared to wild-type mice. | Contact | |||||||||||||
Tg(OvPrP)EM16 | A ~12 kb transgene, comprised of chimaeric DNA sequence encoding a sheep PrP (AHQ allele) coding region and mouse PrP gene promoter and 3' UTR, was used to microinject pronuclear stage FVB/N fertilised oocytes. | Contact |