Title Phenotype Contact
STOCK Tecta<tm3.1Gpr>
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5527094 Tecta<tm3.1Gpr> MGI:109575 Tecta
In Tecta<tm3.1Gpr>/<tm3.1Gpr> homozygotes, the tectorial membrane has a "hump-backed" cross-sectional profile, a much reduced limbal attachment zone and the disruption of the marginal band is exacerbated relative to heterozygotes. High levels of Tecta are detected by immunofluorescence in the tectorial membrane. Mice are susceptible to audiogenic seizures at low sound pressure levels (<84 dB SPL) so should not be exposed to unnecessary noise. Mice have susceptibility to audiogenic seizure at low sound pressure level. Contact
STOCK Tg(ACTA1-Utrn)3Ked Dmd<mdx>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:1856328 Dmd<mdx> MGI:94909 Dmd
MGI:5566891 Tg(ACTA1-Utrn)3Ked MGI:5566890 Tg(ACTA1-Utrn)3Ked
Contact
STOCK Tg(BCL2)36Wehi Tg(Igh2<k>3-83)1Nemz Plcg2<tm1Jni>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3579320 H2<d> MGI:95894 H2
MGI:3052954 Tg(BCL2)36Wehi MGI:3052959 Tg(BCL2)36Wehi
MGI:3055213 Tg(Igh2<k>3-83)1Nemz MGI:3055214 Tg(Igh2<k>3-83)1Nemz
MGI:2386100 Plcg2<tm1Jni> MGI:97616 Plcg2
B cell dysfunction. Homozygotes are infertile. Contact
STOCK Tg(Col2a1-cre)1Bhr/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2176070 Tg(Col2a1-cre)1Bhr              
No overt phenotype. Contact
STOCK Tg(Igf2/LacZ,H19)YZ15Aco/AcoH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5648556 Tg(Igf2/LacZ,H19)YZ15Aco MGI:5648551 Tg(Igf2/LacZ,H19)YZ15Aco
Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. Unlike low copy number lines, the Igf2 LacZ gene does not show appropriate reciprocal imprinting in YZ15 mice as it is expressed from both parental alleles. Contact
STOCK Tg(Igf2/LacZ,H19)YZ17Aco/AcoH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5648555 Tg(Igf2/LacZ,H19)YZ17Aco MGI:5648549 Tg(Igf2/LacZ,H19)YZ17Aco
Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. Deletion of the intergenic region with Cre recombinase results in partial (mesoderm specific) reactivation of Igf2 LacZ expression following maternal transmission. Contact
STOCK Tg(Igf2/LacZ,H19)YZ20Aco/AcoH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5648554 Tg(Igf2/LacZ,H19)YZ20Aco MGI:5648548 Tg(Igf2/LacZ,H19)YZ20Aco
Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over?expressing H19 is not fully characterised. Contact
STOCK Tg(Igf2/LacZ,H19)YZ46Aco/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5648553 Tg(Igf2/LacZ,H19)YZ46Aco MGI:5648550 Tg(Igf2/LacZ,H19)YZ46Aco
Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. Contact
STOCK Tg(Igf2/LacZ,H19)YZ8Aco/AcoH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5648557 Tg(Igf2/LacZ,H19)YZ8Aco MGI:5648552 Tg(Igf2/LacZ,H19)YZ8Aco
Investigating how expression of Igf2 and H19 are regulated is of relevance to understanding Beckwith Weidemann syndrome. The physiological impact of over expressing H19 is not fully characterised. The imprinted H19 gene is only expressed when transmitted through the maternal germline. After paternal transmission the gene is repressed. The Igf2 LacZ gene shows appropriate reciprocal imprinted behaviour (paternal allele specific expression, maternal repression). Contact
STOCK Tg(PRNP*)K6M6Pcg/Pcg
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5775412 Tg(Prnp-PRNP*6OR)K6M6Pcg MGI:5775410 Tg(Prnp-PRNP*6OR)K6M6Pcg
Overexpression of transgenic kudu PrPC in brain and other tissues, in order to confer increased susceptibility to TSE diseases, including BSE, compared to wild-type mice. Contact
STOCK Tg(Prnp-HSPB1)PPks/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5775105 Tg(Prnp-HSPB1)PPks MGI:5775104 Tg(Prnp-HSPB1)PPks
Contact
STOCK Tg(Prnp-SMN)92Ahmb/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3774945 Tg(Prnp-SMN)92Ahmb              
These mice are aphenotypic Contact
STOCK Tg(SMN2)89Ahmb Smg6Tg(SMN1*delta5)1Pks Smn1<tm1Msd>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2183946 Smn1<tm1Msd> MGI:109257 Smn1
MGI:2448989 Grm7<Tg(SMN2)89Ahmb>              
MGI:5493450 Smg6<Tg(SMN1*delta5)1Pks>              
Rescues post natal lethality of SMN2 low strain. Contact
STOCK Tg(SMN2)89Ahmb Smn1<tm1Msd> Tg(SMN1*E134K)1Tlbt/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2183946 Smn1<tm1Msd> MGI:109257 Smn1
MGI:2448989 Grm7<Tg(SMN2)89Ahmb> MGI:2676918 Tg(SMN2)89Ahmb
Mice that are homozygous transgenic for SMN2 and SMN134K and heterozygous or Wt for the Smn knockout allele have no phenotype. Mice that are homozygous transgenic for SMN2 and SMN134K and homozygous deleted for the Smn knockout allele die at approximately P0. Contact
STOCK Tg(Vpreb1-IL2RB)F133Ilm/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5505492 Tg(Vpreb1-IL2RB)F133Ilm MGI:5505484 Tg(Vpreb1-IL2RB)F133Ilm
No known effects Contact
STOCK Tmc1<dn>/WtsiH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:1856845 Tmc1<dn> MGI:2151016 Tmc1
Deafness. Contact
STOCK Tmem255b<tm1a(EUCOMM)Hmgu>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4436032 Tmem255b<tm1a(EUCOMM)Hmgu> MGI:2685533 Tmem255b
To see phenotype data (when available) visit www.mousephenotype.org Contact
STOCK Tpm1<tm1a(EUCOMM)Wtsi>/WtsiH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4842867 Tpm1<tm1a(EUCOMM)Wtsi> MGI:98809 Tpm1
To see phenotype data (when available) visit www.mousephenotype.org Contact
STOCK Trpm1<tm1a(KOMP)Wtsi>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5287780 Trpm1<tm1a(KOMP)Wtsi> MGI:1330305 Trpm1
To see phenotype data (when available) visit www.mousephenotype.org Contact
STOCK Utrn<tm1Ked> Dmd<mdx> Tg(Ckm-Dmd*)11956Chmb/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:1856328 Dmd<mdx> MGI:94909 Dmd
MGI:2148589 Utrn<tm1Ked> MGI:104631 Utrn
MGI:5140820 Tg(Ckm-Dmd*)11956Chmb              
Contact

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