Title | Phenotype | Contact | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
B6;129P2-Capn1<tm1Dgen>/H |
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No overt phenotype. | Contact | ||||||||
B6;129P2-Chd4<tm1.1Bh>/H |
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Both heterozygotes and homozygotes for the floxed allele display no visible phenotype. Heterozygotes for the deleted allele also show no overt phenotype. Homozygotes for the deleted allele die at 3.5 dpc through a failure to develop a trophectoderm and a consequent inability to implant. This strain provides insights into how Chd4 facilitates the first lineage decision making in mammalian embryogenesis. | Contact | ||||||||
B6;129P2-Cxcr1<tm1Dgen>/H |
|
No visible phenotype. | Contact | ||||||||
B6;129P2-Esr2<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Galr2<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Grm1<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Grm4<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Grm5<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Grm8<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Kcnj15<tm1Dgen>/H |
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Kir4.2 potassium channel knockout. | Contact | ||||||||
B6;129P2-Mc2r<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Mc2r<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Npy6r<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Nr1d2<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-P2rx6<tm1Dgen>/H |
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Homozygous mutant mice exhibited a significant increase in thermal response latency during hot plate testing, and required a significantly increased dose of metrazol to reach various seizure stages, when compared with age- and gender-matched wild-type control mice. There were no other significant differences detected in homozygous mutant mice when compared with age- and gender-matched wild-type control mice. | Contact | ||||||||
B6;129P2-Pak2<tm1Dgen>/H |
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None | Contact | ||||||||
B6;129P2-Pde2a<tm1Dgen>/H |
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Heterozygotes: no visible phenotype. Homozygotes: frequently do not survive to weaning age. | Contact | ||||||||
B6;129P2-Pde3a<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Pde4b<tm1Dgen>/H |
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No visible phenotype. | Contact | ||||||||
B6;129P2-Pde4d<tm1Dgen>/H |
|
No visible phenotype. | Contact |