Title Phenotype Contact
STOCK Mut1264/H Craniofacial and behavioural mutant with distal low degree tail kink. Homozygous pre-implantation lethal. Heterozygotes have a flat skull, short, blunt tails with a low degree distal kink and some have white feet. Behavioural abnormalities include head bobbing and erratic behaviour but they can swim. Heterozygotes are approximately 30% smaller than wild-type sibs at birth and weaning. High incidence of exencephaly in fetuses. Contact
STOCK Mut1293/H Heterozygotes are small at birth and weaning. Broad head, bulging eyes, some have ear problems i.e. a build up of a hard white deposit and signs of blood. Penetrance of the phenotype and viability of affected individuals to weaning is good. Homozygotes die post implantation, or survive for longer but are oedematous and have skeletal bone/cartilage abnormalities; limited intercross data suggest that they do not survive post-natally. Contact
STOCK Mut1305/H Small with white toes; sometimes with domed head. Affected heterozygotes are, on average, circa 30% smaller than normal littermates at birth, and about 20% smaller at weaning. Many have white toes; about 15% of affected mice have a noticeably domed head at weaning. Litter sizes are good, suggesting little pre/peri-natal loss of heterozygotes and thus penetrance of mutation phenotype is about 80%. Viability to weaning is about 70%. Homozygotes: data from openings strongly suggest that they die by early post implantation. Contact
STOCK Mut1397/H Heterozygotes: shortened tail with mild to severe kinking and blunt tail tip. Homozygous lethal. Heterozygotes: viability good, but reduced penetrance of phenotype on crossing to 3H1 (circa 70%), much more reduced on crossing to Mus castaneus. Opening and breeding data indicate that homozygotes are lost pre and early post-implantation. Allelism test with t<h2> (MGI:1856184) showed Mut1397 not to be an allele of T (MGI:1856184). Contact
STOCK Mut1488/H Heterozygotes are less than 75% of the weight of their wild-type sibs at birth; limited weight data at weaning suggest that there is a similar size difference at this time point. Mut1488/+ have small eyes, occasionally with domed heads, some have white toes. Breeding data indicate that there is reduced penetrance of the mutation (circa 50%) on a 3H1 background. Data from openings indicate that homozygotes are lost soon after implantation. Contact
STOCK Mut1544/H Heterozygotes have a bruised appearance at birth with bloody areas beneath the skin, most common around the belly and abdomen, some around the neck and back legs. Most also have a domed head. Penetrance of the mutation is slightly reduced, but estimated to be over 70%. Affected offspring are about 20% lighter than normal sibs at birth, and about 35% lighter than wild-type gender matched sibs at weaning. Viability of affected offspring between birth and weaning is estimated to be about 75%. Average litter size of heterozygous females is reduced (estimate: 4.9). Homozygotes: opening data indicate that they probably die by early post implantation, with a large proportion dying pre-implantation. Contact
STOCK Mut1602/H Heterozygotes are small at birth (over 40% lighter than wild-type sibs) and weaning with white hind feet, short tail and head bobbing. Breeding data suggest that penetrance of the mutation is reduced (circa 65%) and that under 60% survive between birth and weaning. Homozygotes are primarily lost post implantation. There is little or no loss of heterozygotes prior to birth. Contact
STOCK Mut921/H Key feature of heterozygotes is a short broad head, wide between eyes, shortened nasal passage with occasional indication of cleft. White feet and belly spots also seen. Small at birth and weaning (approx 30% lighter than wild-type sibs). Recovery at birth reduced due to some prenatal loss of foetuses with more extreme head abnormality. Viability from birth to weaning is circa 60%. Homozygotes are probably lethal pre-implantation. Contact
STOCK Myo7a<26SB>/NihrH Shaker 1 allele. Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wildtypes are indistinguishable from each other. Homozygotes show no preyer reflex. These Myo7a mutants do have severe hearing and vestibular abnormalities. While their retinas do not show any anatomical degeneration, there have been reports of retinal abnormalities. Contact
STOCK Myo7a<3336SB>/NihrH Shaker. Contact
STOCK Myo7a<4494SB>/NihrH shaker Contact
STOCK Myo7a<4626SB>/NihrH Shaker. Deafness, headshaking, circling Contact
STOCK Myo7a<816SB>/NihrH Homozygotes exhibit almost constant circling behaviour. Heterozygotes and wild types are not distinguishable from each other. Homozygotes show no preyer reflex Contact
STOCK Myo7a<sh1-6J>/WtsiH Homozygotes show head bobbing, circling behaviour and deafness.(hyperactivity). Contact
STOCK Ostes/H Muscular dystrophy, small size and muscle wasting. Contact
STOCK Pax2<Opdc>/H Optic disc coloboma. Mutants have retinal vascular abnormalities and optic discs of unusual size. Contact
STOCK Pcdh10<tm1aNarl>/H To see phenotype data (when available) visit www.mousephenotype.org Heterozygotes: males may show increased aggression. Contact
STOCK Pde6b<atrd2>/H Slow onset retinal degeneration. Contact
STOCK Rasgrf1<tm1aNarl>/H To see phenotype data (when available) visit www.mousephenotype.org Contact
STOCK Rsbn1<tm1a(EUCOMM)Wtsi>/H Potential EUMODIC data in the Europhenome database. Contact

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