Title Phenotype Contact
CBA.129S(B6)-Tectb<tm1Gpr>/H Homozygous mutant mice suffer low frequency hearing loss and have ormally attached tectorial membranes that lack striated sheet matrix. Hensen's stripe is missing and the marginal band is absent in the apical coil of the cochlea. Sharpness of high frequency tuning is enhanced. Contact
CBB10-Tg(myl2-cre)1118Tmhn/H Heart (myocardial)-specific CRE driver line (uniform expression of Cre throughout myocardial tissue) Contact
CByIco.129-Rag2<tm1Fwa> Cd44<tm1.1Ugu>/H Rag2-/-: no mature T and B cells. CD44v6v7-/-: strongly reduced symptoms in autoimmune diseases. Contact
CByIco.129-Rag2<tm1Fwa> Cd44<tm1Ugu>/H Chronic intestinal inflammation, colitis. Contact
CByIco.129-Rag2<tm1Fwa> Cd44<tm2.1Ugu>/H Mice are homozygous for both Rag-/- and CD44v10-/- knockouts. Rag2-/-, no mature T and B cells. CD44v10-/-, strongly reduced symptoms in autoimmune diseases. Used in mouse models of experimental colitis. Contact
CByIco.129S-Rag2<tm1Fwa>/H Chronic intestinal inflammation, colitis. Contact
CD1.129P2(B6)-Sox9<tm2Gsr>/H Heterozygous Sox9-neo mice are viable and fertile and display mild skeletal malformations. Homozygous Sox9-neo mice are perinatal lethal (E14-E15) and display severe skeletal defects. Contact
CD1.129P2-Zfp647<Gt(ES492)Hgs>/H No obvious phenotype in homozygotes. Contact
CD1.Cg-Fgfr2<tm4Lni> Heterozygote mice are viable and fertile with shortened face, protruding eyes, and show premature fusion of cranial sutures. Homozygous mutants display multiple joint fusions, cleft palate and trachea and lung defects, and die shortly after birth. Contact
CD1;129-Bmp6<tm1Rob>/H Mice show no overt phenotype. Contact
CD31-Hir-Tg Mice express membrane tethered hirudin-CD4 fusion protein on all CD31+ cells, which includes endothelial cells, monocytes and platelets. In all these, it is internalised within secretory granules at resting state by virtue of P-selectin cytoplasmic sequence. The fusion protein appears on the membrane on activation. The hirudin inhibits thrombin. Contact
CD31-TFPI-Tg Mice express membrane tethered human TFPI-CD4 fusion protein on all CD31+ cells, which includes endothelial cells, monocytes and platelets. In all these, it is internalised within secretory granules at resting state by virtue of P-selectin cytoplasmic sequence. The fusion protein appears on the membrane on activation. The hTFPI inhibits tissue factor and FXa. Contact
Cg.Tg-(ADCYAP1R1)4Sshe/H Homozygotes: high rate of early postnatal death. Homozygotes and heterozygotes: transgene dose-dependent hydrocephalus and/or schizophrenia like neuropathology. This is the line which can be used for X-linked chromosome inactivation, and hydrocephalus-related phenotype studies. See PMID: 16823490. Contact
CHM Flox No known phenotype. Contact
CMV Gal4 None. Contact
Col1a2-Cre-ER(T);Rosa26-floxed stop eYFP Contact
FNOS2 Circling, vestibular defects. Heterozygotes can be identified by mild head bobbing or circling behaviour. Mice with this behaviour usually show morphological changes in the inner ear. Contact
GalR1-mCherry tagged No overt phenotype. Gal1-mCherry fluorescence is associated with primary neuron somatic cell membrane. Gal1-mCherry protein expression seen in dorsal root ganglia, spinal cord and brain tissues. Contact
GalR2- hrGFP tagged No overt phenotype. Gal2 mRNA expression is much lower than Gal1 in dorsal root ganglia. Contact
Gata6cre (C57BL/6J) Gata6 is widely expressed and is an essential gene for embryonic development. The stock has to be maintained heterozygously because the CreER transgenic cassette leads to loss of functional Gata6 expression. Contact

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