Title Phenotype Contact
B6.CAnNCrl(C3H)-Dync1li1<m1Emcf>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4950685 Dync1li1<m1Emcf> MGI:2135610 Dync1li1
Mouse not completely assessed but so far homozygotes have behavioural and neurological changes. Contact
B6.Cg-Cited2<L247P>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5646605 Cited2<m1H> MGI:1306784 Cited2
Although the amino acid change occurs in a highly conserved residue, the mutant is homozygous viable and fertile, with no detectable phenotype. In trans to the Knock-out allele, it is viable and phenotypically normal. Contact
B6.Cg-Ddx5<tm1.1Arte> Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3763211 Gt(ROSA)26Sor<tm9(cre/ESR1)Arte> MGI:104735 Gt(ROSA)26Sor
MGI:5463981 Ddx5<tm1.1Arte> MGI:105037 Ddx5
Mouse strain has no detectable phenotype in the absence of activated Cre. Tamoxifen treatment induces p68 knockout in multiple tissues; this results in hypoplastic bone marrow and alterations in tissue organisation in the large intestine of a high proportion of mice. However, we have only been able to perform short term experiments. These mice would be ideal for the generation of tissue-specific p68 knockout models. Contact
B6.Cg-Mrc2<tm1Cmi>Tg(CAG-EGFP)1Osb/CmiH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2686773 Tg(CAG-EGFP)1Osb              
MGI:3722867 Mrc2<tm1Cmi> MGI:107818 Mrc2
Homozygous transgenic mice are viable, fertile, normal in size, and do not display any gross physical or behavioral abnormalities. All of the tissues, with the exception of erythrocytes and hair, appear green under excitation light. Contact
B6.Cg-Sfrp2<I153N>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3056484 Sfrp2<I153N> MGI:108078 Sfrp2
No overt Phenotype. Full description available from Europhenome. Contact
B6.Cg-Syce1<tm1Hgu>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3840564 Syce1<tm1Hgu> MGI:1921325 Syce1
Mice homozygous for this mutation in this background can not progress to diplotene stages of meiosis and show a failure of synapsis. Heterozygous mice show close to normal fertility. Contact
B6.Cg-Syce2<Gt(FHCRC-GT-S8-7E1)Sor>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3708176 Syce2<Gt(FHCRC-GT-S8-7E1)Sor> MGI:1919096 Syce2
Mice homozygous for this mutation in this background can not progress to diplotene stages of meiosis and show a failure of synapsis. Heterozygous mice show close to normal fertility. Contact
B6.Cg-Tg(ACTFLPe)9205Dym/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2448985 Tg(ACTFLPe)9205Dym              
No overt phenotype. Contact
B6.Cg-Tg(IL3,CSF2)C42Pnc/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5620606 Tg(IL3,CSF2)C42Pnc MGI:5620622 Tg(IL3,CSF2)C42Pnc
No overt phenotype. Contact
B6.Cg-Tg(PRNP-DNAJB2_ia)52aMec/MecH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5613188 Tg(PRNP-DNAJB2_ia)52aMec MGI:5613187 Tg(PRNP-DNAJB2_ia)52aMec
No overt phenotype noted. Contact
B6.Cg-Tg(PRNP-DNAJB2_ia)61aMec/MecH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5613160 Tg(PRNP-DNAJB2_ia)61aMec MGI:5613156 Tg(PRNP-DNAJB2_ia)61aMec
No overt phenotype. Contact
B6.Cg-Tg(RP3-340H11)29Kel/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5308378 Tg(RP3-340H11)29Kel              
Mild hyperglycaemia in neonates, mildly impaired glucose tolerance post weaning. Contact
B6.Cg-Tg(Slc16a1-Luc)50Rttr/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5465430 Tg(Slc16a1-luc)50Rttr MGI:5465433 Tg(Slc16a1-luc)50Rttr
When expressed in pancreatic beta cells it renders insulin secretion sensitive to pyruvate and prevents the normal inhibition of insulin secretion induced by exercise, replicating the key features of Exercise-Induced Hyperinsulinism. Contact
B6.Cg-Tyr<c-Brd> Mir155<tm1.1Brd>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3709881 Mir155<tm1.1Brd> MGI:2676840 Mir155
MGI:3640303 Tyr<c-Brd> MGI:98880 Tyr
No visible phenotype is associated with this mutation but the mice do exhibit reduced lung airway remodelling & deficient B-cell, T-cell & dendritic cell function. This mutation is on a C57BL/6<c-/c-> background and is albino in appearance. The BIC mice (EMMA ID EM:02231) have been backcrossed at least 5 times to C57BL/6, thus making them suitable for bone marrow transplantation, without rejection, to any C57BL/6 mice, regardless of coat color. Contact
B6129S8-Tc(Hsa21)1TybEmcf/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3814712 Tc(HSA21)1TybEmcf MGI:3814702 Tc(HSA21)1TybEmcf
This strain displays learning abnormalities, reduced long-term potentiation in the hippocampus, heart and brain developmental defects, craniofacial dysmorphology (this strain models human Down syndrome). Contact
B6;129-Anxa6<tm1Moss>
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2159012 Anxa6<tm1Moss> MGI:88255 Anxa6
Homozygotes have altered mechanical and intracellular calcium signalling in cardiomyocytes. They display altered regulation of mitochondrial morphogenesis. Western blot studies indicate that no detectable protein is produced. Original chimaeric mouse was crossed to C57BL/6 then strain has been maintained by sib crossing for 20 generations. Contact
B6;129-Apoe<tm1Bres> Lgals3<tm1Ftl>/CljH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2386938 Lgals3<tm1Ftl> MGI:96778 Lgals3
MGI:2137814 Apoe<tm1Bres> MGI:88057 Apoe
No overt phenotype reported. Contact
B6;129-Brca1<tm1Aash>/Aash
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3706167 Brca1<tm1Aash> MGI:104537 Brca1
No visible phenotype. Contact
B6;129-Ccr9<tm1Dgen>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5009291 Ccr9<tm1Dgen> MGI:1341902 Ccr9
MGI report that homozygotes have impaired coordination. Contact
B6;129-Flrt2<tm1c(EUCOMM)Wtsi>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
              MGI:3603594 Flrt2
Both heterozygotes and homozygotes have no overt phenotype. Contact

Pages