Title Phenotype Contact
B6.Cg-Tg(IL3,CSF2)C42Pnc/H No overt phenotype. Contact
B6.Cg-Tg(PRNP-DNAJB2_ia)52aMec/MecH No overt phenotype noted. Contact
B6.Cg-Tg(PRNP-DNAJB2_ia)61aMec/MecH No overt phenotype. Contact
B6.Cg-Tg(RP3-340H11)29Kel/H Mild hyperglycaemia in neonates, mildly impaired glucose tolerance post weaning. Contact
B6.Cg-Tg(Slc16a1-Luc)50Rttr/H When expressed in pancreatic beta cells it renders insulin secretion sensitive to pyruvate and prevents the normal inhibition of insulin secretion induced by exercise, replicating the key features of Exercise-Induced Hyperinsulinism. Contact
B6.Cg-Tyr<c-Brd> Mir155<tm1.1Brd>/H No visible phenotype is associated with this mutation but the mice do exhibit reduced lung airway remodelling & deficient B-cell, T-cell & dendritic cell function. This mutation is on a C57BL/6<c-/c-> background and is albino in appearance. The BIC mice (EMMA ID EM:02231) have been backcrossed at least 5 times to C57BL/6, thus making them suitable for bone marrow transplantation, without rejection, to any C57BL/6 mice, regardless of coat color. Contact
B6129S8-Tc(Hsa21)1TybEmcf/H This strain displays learning abnormalities, reduced long-term potentiation in the hippocampus, heart and brain developmental defects, craniofacial dysmorphology (this strain models human Down syndrome). Contact
B6;129-Anxa6<tm1Moss> Homozygotes have altered mechanical and intracellular calcium signalling in cardiomyocytes. They display altered regulation of mitochondrial morphogenesis. Western blot studies indicate that no detectable protein is produced. Original chimaeric mouse was crossed to C57BL/6 then strain has been maintained by sib crossing for 20 generations. Contact
B6;129-Apoe<tm1Bres> Lgals3<tm1Ftl>/CljH No overt phenotype reported. Contact
B6;129-Brca1<tm1Aash>/Aash No visible phenotype. Contact
B6;129-Ccr9<tm1Dgen>/H MGI report that homozygotes have impaired coordination. Contact
B6;129-Flrt2<tm1c(EUCOMM)Wtsi>/RobH Both heterozygotes and homozygotes have no overt phenotype. Contact
B6;129-Fshr<tm1Mha>/H Homozygous males are fertile, but testis weight is reduced (~50% of normal). Homozygous females are infertile, ovulation does not occur. Heterozygous males are indistinguishable from wild type. Contact
B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH The Fucci system was developed by fusing red- and green-emitting fluorescent proteins to the E3 ligase substrates, Cdt1 and Geminin. These fluorescent probes make it possible to distinguish between cells in the G1 or S/G2/M phases of the cell cycle in live cells/tissue (Sakaue-Sawano al 2008). Fucci2a is a bicistronic version of Fucci2 allowing Cre-mediated tissue-specific expression in mice (Mort, R et al 2014). Contact
B6;129-Khdrbs3<tm1Dell>/DellH These mice do not express T-STAR protein by Western blotting Contact
B6;129-Nek6<tm1Dgen>/H No visible phenotype. Contact
B6;129-P2ry12<tm1Dgen>/H None Contact
B6;129-Ptprc<tm1Holm>/H Defective lymphocyte development, more severe in T lineage, severe combined immunodeficiency. Contact
B6;129-Reg2<tm1Lchr>/H Viable, normal breeding pattern, no obvious phenotype. Contact
B6;129-Scn10a<tm3(cre/ERT2)Jnw>/H None observed (heterozygous Nav1.8-CreERT2 can express enough Cre to delete the floxed fragment, but it does not affect the expression of Nav1.8 in Nav1.8 positive neurons in DRG). Contact