Title Phenotype Contact
B10ScSn.BXSB-(D1Mit33-D1Mit223) Chr Y<BXSB/MpJ>/BjmjrH ANA, 75% mortality, enhanced autoantibody titre, severe glomerulonephritis. Contact
B6(C)-Npr3<Kylb>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:6269452 Npr3<kylb>              
Homozygotes have an small and elongated body, kyphosis and long bones. Contact
B6(Cg)-Clec9a<tm1.1Crs>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5298406 Clec9a<tm1.1Crs> MGI:2444608 Clec9a
The CD8+ve family of dendritic cells lack expression of DNGR-1 (CLEC9) and are impaired in the cross-priming of T-cells. Contact
B6(Cg)-Grik4<tm1.1(cre)Slab>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4398684 Grik4<tm1.1(cre)Slab> MGI:95817 Grik4
Cre mouse with restricted expression in subregions of the hippocampus, mainly in CA3 and absent in CA1. No obvious phenotype in the absence of a target allele Contact
B6(Cg)-Klra5<tm1.1Cgbr>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4941892 Klra5<tm1.1Cgbr> MGI:101903 Klra5
Lack of expression of Ly49E. Expression of b-geo. No other known phenotype at present. Contact
B6.129-Abcc8<tm1.1Fmas>/LaakFmasH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5568409 Abcc8<tm1.1Fmas> MGI:1352629 Abcc8
Homozygous mice develop mild glucose intolerance with age due to a reduction in insulin content in the pancreatic beta-cell. Heterozygous mice are far less affected. Unlike in humans, there is no clear hyperinsulinism in the neonatal period. Contact
B6.129-Anpep<tm1Afk>/AfkH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5582781 Anpep<tm1Afk> MGI:5000466 Anpep
No overt phenotype is seen in mice homozygous for Anpep<tm1aAfk>. However, a delay in mammary development was detected. Similar knock-outs for Anpep have shown a deficiency in tumour vascularisation. This was not assessed for this mutated allele. Heterozygotes had no detectable phenotype. See PMID:22983824. Contact
B6.129-Cited2<tm2Bha>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3803778 Cited2<tm2Bha> MGI:1306784 Cited2
Cre-mediated recombination throughout the entire epiblast of early embryos recapitulates the complete loss of function phenotype of Cited2, which include cardiac malformations, adrenal agenesis, fusion of cranial ganglia, abnormal cardiac neural crest migration, excencephaly and left right patterning defects. Contact
B6.129-Flrt2<tm1Rob>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4950410 Flrt2<tm1Rob> MGI:3603594 Flrt2
Mouse embryos deficient in Flrt2 display defects in heart morphogenesis, in particular, defects in the integrity of the epicardium and disturbances to the architecture of the underlying basement membrane accompanied by a pronounced reduction in thickness of the ventricular myocardium. A small proportion of homozygous mutants survive gestation (<3%). Heterozygous mice have no overt phenotype. Contact
B6.129-Krt36<tm1Hpt>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
              MGI:109364 Krt36
Hyperkeratosis of scales (tail) and filiform papillae (tongue). The analyses are not yet complete but if present, the phenotype is very weak in heterozygotes. An obvious hyperkeratosis is however apparent in homozygous mutant animals. Contact
B6.129-Mrc2<tm1Cmi>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3722867 Mrc2<tm1Cmi> MGI:107818 Mrc2
Homozygous Endo180DeltaEx2-6/Endo180DeltaEx2-6 mice are phenotypically normal (at the gross level), healthy and fertile. Contact
B6.129-Nrxn2<tm1Sud>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3042719 Nrxn2<tm1Sud> MGI:1096362 Nrxn2
Mice homozygous for a knock-out allele show a 30-40% decrease in body weight and their inhibitory postsynaptic currents (IPSCs) are decreased in cortical slice cultures. Further phenotyping data to be published shortly. Contact
B6.129-Prdm1<tm1.1Liz>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4366868 Prdm1<tm1.1Liz> MGI:99655 Prdm1
No overt phenotype. Mice with targeted exon 1A deletion show that Prdm1 expression has been eliminated in LPS-stimulated B cells and plasma cell differentiation has been blocked. Embryonic development is not disrupted, and embryos with this deletion show modestly reduced Prdm1 expression levels. Contact
B6.129-Prdm1<tm1.1Liz>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4366868 Prdm1<tm1.1Liz> MGI:99655 Prdm1
No overt phenotype. Mice with targeted exon 1A deletion show that Prdm1 expression has been eliminated in LPS-stimulated B cells and plasma cell differentiation has been blocked. Embryonic development is not disrupted, and embryos with this deletion show modestly reduced Prdm1 expression levels. Contact
B6.129-Prdm1<tm2.1Liz>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4366869 Prdm1<tm2.1Liz> MGI:99655 Prdm1
No overt phenotype. Mice with targeted exon 1B deletion have slightly decreased expression in the yolk sac but show no other noticeable effects in embryo or adult tissues. Contact
B6.129-Prdm1<tm3.1Liz>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5491215 Prdm1<tm3.1Liz> MGI:99655 Prdm1
Homozygotes are lethal and die around E10.5 due to placental defects. Heterozygotes have no overt phenotype. Contact
B6.129-Prdm1<tm4.1Liz>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5491216 Prdm1<tm4.1Liz> MGI:99655 Prdm1
Homozygotes and heterozygotes show no overt phenotype. Contact
B6.129-Prdm4<tm2.1Liz>/RobH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5547614 Prdm4<tm2.1Liz> MGI:1920093 Prdm4
Mice with targeted deletion of the zinc finger domain have no phenotype. Heterozygotes also have no overt phenotype. Contact
B6.129-S100A10<tm1Jnw>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3665443 S100a10<tm1Jnw> MGI:1339468 S100a10
None. Contact
B6.129-Scn10a<tm2(cre)Jnw>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3053096 Scn10a<tm2(cre)Jnw> MGI:108029 Scn10a
No phenotype in heterozygotes. Some pain deficits in homozygotes. Contact

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