Title Phenotype Contact
Acot7 tg When bred with animals expressing rtTA specifically in beta cells and, upon Doxycicline administration, the mice develop mild glucose intolerance, impaired insulin secretion in response to glucose and the islets present reduced levels of FA-CoA. Contact
Angelina Increased marginal zone size with age and activated peripheral CD8 T cells. Contact
Antonia An ENU-induced mutation causing heritable anti-nuclear antibodies and variable proliferative and membranous glomerulonephritis with partial dominant phenotype and penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry and immunoglobulin levels. Contact
Arap1-tg Overexpression of the transgene after crossing with mice expressing the reverse tetracycline transactivator and given doxycycline in drinking water (possibility of inducing overexpression in a specific tissue). Contact
B(BR)-Steap3<fred>/Apb Abnormalities in red blood cell size and shape. Contact
B.Cg-Pgk1<a>/WsH Contact
B.Cg-Tg(Hbb-b1)83Clo/WsH None expressed. Contact
B10.Cg-H2<k2> Tg(CD2-Ptpn11*C459S)1Axdr/AxdrH Characterisation of phenotype still in progress but line displays defective primary immune responses to T-dependent antigen and amplified cytokine secretion in response to antgenic challenge. Contact
B10ScSn.BXSB-(D1Mit123-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH Enhanced autoantibody spectrum and titre. Glomerulonephritis susceptibility. Contact
B10ScSn.BXSB-(D1Mit235-D1Mit1000) Chr Y<BXSB/MpJ>/BjmjrH Glomerulonephritis susceptibility. Contact
B10ScSn.BXSB-(D1Mit3-D1Mit235) Chr Y<BXSB/MpJ>/BjmjrH Enhanced autoantibody spectrum and titre. Contact
B10ScSn.BXSB-(D1Mit3-D1Mit320) Chr Y<BXSB/MpJ>/BjmjrH Enhanced autoantibody spectrum and titre. Contact
B10ScSn.BXSB-(D1Mit303-D1Mit305) Chr Y<BXSB/MpJ>/BjmjrH Glomerulonephritis susceptibility. Contact
B10ScSn.BXSB-(D1Mit33-D1Mit223) Chr Y<BXSB/MpJ>/BjmjrH ANA, 75% mortality, enhanced autoantibody titre, severe glomerulonephritis. Contact
B6(Cg)-Clec9a<tm1.1Crs>/H The CD8+ve family of dendritic cells lack expression of DNGR-1 (CLEC9) and are impaired in the cross-priming of T-cells. Contact
B6(Cg)-Grik4<tm1.1(cre)Slab>/H Cre mouse with restricted expression in subregions of the hippocampus, mainly in CA3 and absent in CA1. No obvious phenotype in the absence of a target allele Contact
B6(Cg)-Klra5<tm1.1Cgbr>/H Lack of expression of Ly49E. Expression of b-geo. No other known phenotype at present. Contact
B6.129-Abcc8<tm1.1Fmas>/LaakFmasH Homozygous mice develop mild glucose intolerance with age due to a reduction in insulin content in the pancreatic beta-cell. Heterozygous mice are far less affected. Unlike in humans, there is no clear hyperinsulinism in the neonatal period. Contact
B6.129-Anpep<tm1Afk>/AfkH No overt phenotype is seen in mice homozygous for Anpep<tm1aAfk>. However, a delay in mammary development was detected. Similar knock-outs for Anpep have shown a deficiency in tumour vascularisation. This was not assessed for this mutated allele. Heterozygotes had no detectable phenotype. See PMID:22983824. Contact
B6.129-Cited2<tm2Bha>/H Cre-mediated recombination throughout the entire epiblast of early embryos recapitulates the complete loss of function phenotype of Cited2, which include cardiac malformations, adrenal agenesis, fusion of cranial ganglia, abnormal cardiac neural crest migration, excencephaly and left right patterning defects. Contact

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