Title Phenotype Contact
129P2/OlaHsdH-Prnp<tm2Edin>/H No expression of the Prnp gene. Abnormalities in synaptic transmission, circadian rhythm and sleep. Increased susceptability to oxidative stress and copper toxicity. Cellular phenotypes in T cell activation. Contact
129S(B6)-Gnas<tm2Kel>/H There is a behavioural phenotype: response to novel environments as measured through activity in various tasks. This targeted allele has been shown to represent a null for Nesp55 protein. Contact
129S(Cg)-Foxh1<tm1Jlw>/H Homozygous lethal at day 8 of gestation. Contact
129S.129P2-Cited2<tm1Bha>/H Contact
129S/SvEv-Gt(ROSA)26Sor<tm1Coll>/H No obvious phenotype. Contact
129S/SvEv-Klf13<tm1Coll>/CollH Mice show altered T, B cell & erythroblast differentiation. Contact
129S/SvEvBrd-Brd7<tm2a(EUCOMM)Wtsi>/WtsiH Potential EUMODIC data in the Europhenome database. Contact
129S/SvEvBrd-Mta1<tm1a(EUCOMM)Wtsi>/WtsiH Potential EUMODIC data in the Europhenome database. Contact
129S/SvEvBrd-Mta1<tm1a(EUCOMM)Wtsi>/WtsiH Potential EUMODIC data in the Europhenome database. Contact
129S2(B6)-Meg3<Gt(pGTi)216Gos>/H Imprinted dwarfism and thyroid hormone defects. This transgenic mouse line carries an insertional mutation with a dominant modified pattern of inheritance: heterozygous Gtl2 lacZ mice that inherited the transgene from the father show a proportionate dwarfism phenotype; whereas the penetrance and expressivity of the phenotype is strongly reduced in Gtl2 lacZ mice that inherited the transgene from the mother. On a mixed genetic background this pattern of inheritance was reversible upon transmission of the transgene through the germ line of the opposite sex whereas on a predominantly 129S2/SvPas genetic background the transgene passage through the female germ line modifies the transgene effect, such that the penetrance of the mutation was drastically reduced and the phenotype is no longer obvious after subsequent male germ line transmission. Expression of the transgene is neither affected by genetic background nor by parental legacy. It has been postulated that that the transgene insertion in Gtl2 lacZ mice affects an endogenous gene(s) required for fetal and postnatal growth and that this gene(s) is predominantly paternally expressed. Contact
129S2.129P2-Ccl6<tm1Roes>/H None mentioned. Contact
129S2.Cg-Tg(KRT10-Igfr2*)KippsGfc/H Slightly reduced overall body weight, disproportionate reduction in size of alimentary canal and uterus. Contact
129S2;129P2-Gca<tm1Roes>/H Minimal. Contact
129S5;B6N-Kdm6a<tm2a(EUCOMM)Wtsi>/WtsiH To see phenotype data (when available) visit www.mousephenotype.org Contact
129S6.129P2(Cg)-Fgfr3<tm1.1Aomw>/AomwH All homozygous males, some homozygous females and some heterozygous males develop an abnormal skull phenotype sometimes with malocclusion, and may be smaller in size. The phenotype is not fully penetrant. Refer to publication for further information: PMID:19086028. Contact
129S9.B6-a/H Black coat colour. The non-agouti locus from C57BL/6J has been bred to congenicity on a 129S9/SvEvH background. This stock is homozygous for non-agouti (a/a). Contact
129S9/SvEvH-Evta/H White coat with non-agouti specking and occasional non-agouti patches. Contact
2700049A03Rik<tm1.1Arte> Crossing talpid3 floxed mutant mice with Cre mice leads to functional inactivation of the Talpid3 gene and hence loss of cilia. Contact
A.129P2-Nat2<tm1Esim>/H No overt phenotype. Contact
ABH.Cg-Tg(CEBP-luc)15Mgls/H Bioluminescence activity in brain. Contact

Pages